Development of an implantable device to monitor lactate levels in blood: Monitoring the Performance of Australian athletes using Biosensor Technology. Sport is a critical area for social and economic investments. Novel medical monitoring systems using implantable biosensors will ensure optimal training programs for Australian athletes and maintain international competitiveness. Here we are developing a biosensor for real-time monitoring of lactate levels in athletes using frontier porous semicon ....Development of an implantable device to monitor lactate levels in blood: Monitoring the Performance of Australian athletes using Biosensor Technology. Sport is a critical area for social and economic investments. Novel medical monitoring systems using implantable biosensors will ensure optimal training programs for Australian athletes and maintain international competitiveness. Here we are developing a biosensor for real-time monitoring of lactate levels in athletes using frontier porous semiconductor technology and smart telemetry protocols to transfer the readings to a remote base unit. These highly innovative devices and the materials that they are made from have enormous commercial potential in biomedical engineering. There is a strong potential for Australia to have an important stake in this area by combining expertise in engineering, chemistry and nanostructured materials.Read moreRead less
Maximising Economic Returns In The NT Spanish Mackerel Fishery
Funder
Fisheries Research and Development Corporation
Funding Amount
$26,307.36
Summary
Objectives: 1. To assess the impact of bleeding , gutting and deheading on the quality of spanish mackerel 2. To determine the impact of spiking and icing on the onset of rigor in spanish mackerel 3. To evaluate the effect of storage on ice on the shelf life and sensory properties of spanish mackerel 4. To assist in the preparation of a Code of Practice for the capture, handling and packaging of chilled spanish mackerel
I am a virologist exploiting basic and applied research on hepatitis viruses to develop biotechnology innovations in diagnostics and vaccines for a broad range of infectious diseases
Investigation Of Key Factors In The Maintenance Of Quality From Catching To Consumer
Funder
Fisheries Research and Development Corporation
Summary
Objectives: 1. To maintain high quality by correct freezing procedures, 2. To understand the characteristic properties of the trawl fish of South-east Australia and of the North-west Shelf
Discovery Early Career Researcher Award - Grant ID: DE170100068
Funder
Australian Research Council
Funding Amount
$390,000.00
Summary
Bioinspired liposome-based smart sensors. This project aims to develop a liposome-based biosensor technology that mimics cell sensory systems. Selective detection of compounds is increasingly important for food, health and environmental monitoring. Biosensor development faces long-standing challenges such as response time, sensitivity, specificity, and multiplexing. On the other hand, cells can sense and discriminate multiple biomolecules in seconds with high sensitivity and specificity. This pr ....Bioinspired liposome-based smart sensors. This project aims to develop a liposome-based biosensor technology that mimics cell sensory systems. Selective detection of compounds is increasingly important for food, health and environmental monitoring. Biosensor development faces long-standing challenges such as response time, sensitivity, specificity, and multiplexing. On the other hand, cells can sense and discriminate multiple biomolecules in seconds with high sensitivity and specificity. This project aims to harness cells’ exquisite biological properties to improve current detection techniques. It will integrate liposome-based sensors with microfluidics to perform analytical tasks ranging from food safety to diagnostics.Read moreRead less
Atlantic Salmon Aquaculture Subprogram: Characterisation Of EST03G12 And Elucidation Of Its Role In Amoebic Gill Disease (AGD) Severity
Funder
Fisheries Research and Development Corporation
Funding Amount
$135,629.00
Summary
Preliminary studies of salmon EST03G12 undertaken within FRDC Project #2004/218 did not determine whether it encodes a functional protein and therefore it's biological role in AGD pathology remains largely unknown. However, some evidence was obtained that it might function as either a negative regulator of the innate immune response or a transcriptional factor driving the hyperproliferation of gill cells observed at sites of AGD lesions. Thus it might play a significant role in the development ....Preliminary studies of salmon EST03G12 undertaken within FRDC Project #2004/218 did not determine whether it encodes a functional protein and therefore it's biological role in AGD pathology remains largely unknown. However, some evidence was obtained that it might function as either a negative regulator of the innate immune response or a transcriptional factor driving the hyperproliferation of gill cells observed at sites of AGD lesions. Thus it might play a significant role in the development of AGD pathology and in progress the disease. Indeed, if EST03G12 expression impacts negatively on the innate immune response against AGD, it is an obvious target for intervention strategies. However, in order to devise such strategies there is a need to better characterise the EST to examine whether it encodes a functional protein, it's role during the progress of AGD and whether allelic differences in the gene sequence and/or its promoter amongst salmon correlate with differences in their resistance/susceptibility to AGD. Objectives: 1. Determine whether EST03G12 encodes a functional protein 2. Characterise the role of EST03G12 in AGD pathogenesis 3. Identify polymorphisms and allele frequencies of EST03G12 in Tasmanian farmed salmon 4. Determine whether different EST03G12 alleles confer resistance/susceptibility to AGD Read moreRead less
Porous silicon biosensor for rapid detection of water-borne contaminants. We have recently demonstrated the rapid degradation of porous silicon by certain transition metal complexes known as biomimetic catalysts. The catalysed degradation forms the basis of a new sensor principle where the porous layer serves as matrix, transducer and signal amplification stage. Using this mechanism, we will develop a biosensor for the rapid detection of contaminants (toxins etc.) in water resources. Reservoir w ....Porous silicon biosensor for rapid detection of water-borne contaminants. We have recently demonstrated the rapid degradation of porous silicon by certain transition metal complexes known as biomimetic catalysts. The catalysed degradation forms the basis of a new sensor principle where the porous layer serves as matrix, transducer and signal amplification stage. Using this mechanism, we will develop a biosensor for the rapid detection of contaminants (toxins etc.) in water resources. Reservoir water treatment today is reactive rather than preventive because current analysis is slow. Our biosensor can be turned into a field kit to improve water quality management and prevent acts of deliberate sabotage to the water supply.Read moreRead less
A gold-coated magnetic nanoparticle biosensor for detecting microRNA. The project aims to develop a biosensor for detecting short sequences of RNA, called microRNA (miRNA) in blood. There are about 100 miRNA sequences that are involved in most biological processes. Changes in the levels of some miRNA sequences can serve as a biomarker for many diseases including cancers. The miRNA will be detected using gold-coated magnetic nanoparticles modified with DNA sequences complementary to the miRNA of ....A gold-coated magnetic nanoparticle biosensor for detecting microRNA. The project aims to develop a biosensor for detecting short sequences of RNA, called microRNA (miRNA) in blood. There are about 100 miRNA sequences that are involved in most biological processes. Changes in the levels of some miRNA sequences can serve as a biomarker for many diseases including cancers. The miRNA will be detected using gold-coated magnetic nanoparticles modified with DNA sequences complementary to the miRNA of interest to capture the miRNA. Application of a magnetic field allows the levels of miRNA to be detected electrochemically. The expected outcome is a commercialisable biosensor for miRNA both as a diagnostic early detection device and a prognostic device for a range of miRNA biomarkers.Read moreRead less
SCRC: PhD 5.03 The Role Of Inbound Chinese Tourists In Promoting Australian Seafood Products In China (student Jasha Bowe)
Funder
Fisheries Research and Development Corporation
Summary
This PhD proposal focuses on CRC's Program 1 goals. The key focus is on increased demand for Australian seafood in China, but our research has implications for marketing to any country that has substantial tourism in Australia: i.e., US, UK, mainland Europe, southern Asia. The project aims to reduce the costs and increasing the efficiency of promotion to higher income consumers, which should result in increased profitability throughout the value chain. The long term outcome should be additional ....This PhD proposal focuses on CRC's Program 1 goals. The key focus is on increased demand for Australian seafood in China, but our research has implications for marketing to any country that has substantial tourism in Australia: i.e., US, UK, mainland Europe, southern Asia. The project aims to reduce the costs and increasing the efficiency of promotion to higher income consumers, which should result in increased profitability throughout the value chain. The long term outcome should be additional profit margins through improved market access.Read moreRead less