ORCID Profile
0000-0003-4263-9972
Current Organisation
University of Melbourne
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Research Topics
In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Top 5 Research Topics
ANZSRC Field of Research (FoR)
Electrical and Electronic Engineering | Photonics and Electro-Optical Engineering (excl. Communications) | Signal Processing | Microelectronics and Integrated Circuits | Biological Physics | Nanotechnology | Electronic and Magnetic Properties of Condensed Matter; Superconductivity | Optical Fibre Communications | Nanoelectronics | Neurocognitive Patterns and Neural Networks | Biomedical Instrumentation | Medical Devices | Condensed Matter Physics | Interdisciplinary Engineering not elsewhere classified | Biomedical Engineering | Pharmacogenomics | Wireless Communications | Nanophotonics | Nanotechnology not elsewhere classified | Decision Making | Nanomaterials | Communications Technologies | Stochastic Analysis and Modelling | Neurosciences | Central Nervous System | Quantum Optics | Photonics, Optoelectronics and Optical Communications | Nanofabrication, Growth and Self Assembly
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in Technology | Expanding Knowledge in Engineering | Integrated Circuits and Devices | Communication Networks and Services not elsewhere classified | Manufacturing not elsewhere classified | Medical Instruments | Expanding Knowledge in the Physical Sciences | Scientific Instruments | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in Psychology and Cognitive Sciences | Expanding Knowledge in the Medical and Health Sciences | Diagnostic Methods | Industrial Instruments | Industrial Chemicals and Related Products not elsewhere classified | Network Infrastructure Equipment |
Related Links
Publications
A 20 pJ/b (10 μW) digital receiver based on a new modulation (SAS) for retinal prosthesis application
Publisher: IEEE
Date: 04-2011
Decreased expression of mGluR5 within the dorsolateral prefrontal cortex in autism and increased microglial number in mGluR5 knockout mice: Pathophysiological and neurobehavioral implications
Publisher: Elsevier BV
Date: 10-2015
DOI: 10.1016/J.BBI.2015.05.009
Abstract: Metabotropic glutamate receptor 5 (mGluR5) and microglial abnormalities have been implicated in autism spectrum disorder (ASD). However, controversy exists as to whether the receptor is down or upregulated in functioning in ASD. In addition, whilst activation of mGluR5 has been shown to attenuate microglial activation, its role in maintaining microglial homeostasis during development has not been investigated. We utilised published microarray data from the dorsolateral prefrontal cortex (DLPFC) of control (n=30) and ASD (n=27) in iduals to carry out regression analysis to assess gene expression of mGluR5 downstream signalling elements. We then conducted a post-mortem brain stereological investigation of the DLPFC, to estimate the proportion of mGluR5-positive neurons and glia. Finally, we carried out stereological investigation into numbers of microglia in mGluR5 knockout mice, relative to wildtype littermates, together with assessment of changes in microglial somal size, as an indicator of activation status. We found that gene expression of mGluR5 was significantly decreased in ASD versus controls (p=0.018) as well as downstream elements SHANK3 (p=0.005) and PLCB1 (p=0.009) but that the pro-inflammatory marker NOS2 was increased (p=0.047). Intensity of staining of mGluR5-positive neurons was also significantly decreased in ASD versus controls (p=0.016). Microglial density was significantly increased in mGluR5 knockout animals versus wildtype controls (p=0.011). Our findings provide evidence for decreased expression of mGluR5 and its signalling components representing a key pathophysiological hallmark in ASD with implications for the regulation of microglial number and activation during development. This is important in the context of microglia being considered to play key roles in synaptic pruning during development, with preservation of appropriate connectivity relevant for normal brain functioning.
A method for evaporating silicon to form low dimensional Si lattice structures
Publisher: SPIE
Date: 07-12-2013
DOI: 10.1117/12.2033660
Routing and localization for extended lifetime in data collection wireless sensor networks
Publisher: IEEE
Date: 2008
Subspace-based methods for crosstalk cancellation in OFDM systems
Publisher: IEEE
Date: 2008
Enhanced thermoelectric performance of graphene nanoribbon-based devices
Publisher: AIP Publishing
Date: 24-03-2016
DOI: 10.1063/1.4944710
Abstract: There have been numerous theoretical studies on exciting thermoelectric properties of graphene nano-ribbons (GNRs) however, most of these studies are mainly based on simulations. In this work, we measure and characterize the thermoelectric properties of GNRs and compare the results with theoretical predictions. Our experimental results verify that nano-structuring and patterning graphene into nano-ribbons significantly enhance its thermoelectric power, confirming previous predictions. Although patterning results in lower conductance (G), the overall power factor (S2G) increases for nanoribbons. We demonstrate that edge roughness plays an important role in achieving such an enhanced performance and support it through first principles simulations. We show that uncontrolled edge roughness, which is considered detrimental in GNR-based electronic devices, leads to enhanced thermoelectric performance of GNR-based thermoelectric devices. The result validates previously reported theoretical studies of GNRs and demonstrates the potential of GNRs for the realization of highly efficient thermoelectric devices.
Experimental demonstration of a novel indoor optical wireless localization system for tracking multiple users
Publisher: IEEE
Date: 08-2011
A hybrid routing protocol for wireless sensor networks
Publisher: IEEE
Date: 10-2007
Design and implementation of an 11-bit 50-MS/s split SAR ADC in 65 nm CMOS
Publisher: IEEE
Date: 06-2014
Microglial activation and progressive brain changes in schizophrenia
Publisher: Wiley
Date: 08-01-2016
DOI: 10.1111/BPH.13364
A low-power, small-area and programmable bandgap reference
Publisher: IEEE
Date: 08-2012
Polarization insensitive vertical coupler for multi-layer silicon photonic integrated circuits
Publisher: IEEE
Date: 04-2015
Robust estimation of GCD with sparse coefficients
Publisher: Elsevier BV
Date: 03-2010
8×40-Gb/s optical coherent pol-mux single carrier system with frequency domain equalization and training sequences
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2012
Emergence of competitive control in a memristor-based neuromorphic circuit
Publisher: IEEE
Date: 06-0011
A GFSK demodulator for ultra-low power MICS band receiver
Publisher: IEEE
Date: 12-2010
Indoor gigabit full-duplex optical wireless communication system with SCM based multiple-user access
Publisher: IEEE
Date: 10-2011
Graphene Self Switching Diodes with high rectification ratios
Publisher: IEEE
Date: 08-2013
Experimental demonstration of indoor infrared optical wireless communications with a silicon photonic integrated circuit
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 15-01-2019
Investigation of frequency-dependent effects in inductive coils for implantable electronics
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2013
Dielectric properties of liquid phase molecular clusters using the external field method: molecular dynamics study
Publisher: Royal Society of Chemistry (RSC)
Date: 2014
DOI: 10.1039/C4CP00716F
Abstract: A method based on molecular dynamics simulations is presented to determine dielectric properties of materials under external electric fields without prior knowledge of their static dielectric constant, using reaction field approximations.
Experimental Demonstration of 3 × 10 Gbps Reconfigurable High-Speed Optical Wireless Interconnects
Publisher: OSA
Date: 2012
Training sequences in 16-QAM and QPSK coherent pol-mux single-carrier systems
Publisher: IEEE
Date: 09-2012
A ultra low power, wide input range MICS band channel selection filter on 65 nm CMOS
Publisher: IEEE
Date: 11-2010
Crosstalk current measurements using multi-electrode arrays in saline
Publisher: IEEE
Date: 08-2012
Functionalized Nanowire-Based Antigen Detection Using Frequency-Based Signals
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2012
Dual-stage frequency domain blind equalization for long-haul coherent polarization-multiplexed qpsk and 16-qam systems
Publisher: OSA
Date: 2012
Improved HLA-based prediction of coeliac disease identifies two novel HLA risk modifiers, DQ6.2 and DQ7.3
Publisher: Cold Spring Harbor Laboratory
Date: 05-03-2019
DOI: 10.1101/561308
Abstract: Human Leukocyte Antigen (HLA) testing is useful in the clinical work-up of coeliac disease (CD), with high negative but low positive predictive value. We construct a genomic risk score (GRS) using HLA risk loci to improve CD prediction and guide exclusion criteria. Imputed HLA genotypes for five European CD case-control GWAS (n ,000) were used to construct and validate an HLA based risk models ( HDQ 15 ). Conditioning on this score, we identified novel HLA interactions which modified CD risk, and integrated these novel alleles into a new risk score ( HDQ 17 ). A GRS from HLA risk allele genotypes yields performance equivalent to a state-of-the-art GRS (GRS 228 ) using 228 single nucleotide polymorphisms (SNPs) and significantly improves upon all previous HLA based risk models. Conditioning on this model, we find two novel associations, HLA-DQ6.2 and HLA-DQ7.3, that interact significantly with HLA-DQ2.5 (p = 2.51 × 10 −9 , 1.99 × 10 −7 for DQ6.2 and DQ7.3 respectively). These epistatic interactions yield the best performing risk score ( HDQ 17 ) which retains performance when implemented using 6 tag SNPs. Using the HDQ 17 model, the positive predictive value of CD testing in high risk populations increases from 17.5% to 27.1% while maintaining a negative predictive value above 99%. Our proposed HLA-based GRS achieves state-of-the-art risk prediction, helps elucidate further risk factors and improves HLA typing exclusionary criteria, which may reduce the number of patients requiring unnecessary endoscopies.
High-Q flexible spiral inductive coils
Publisher: IEEE
Date: 09-2010
Two-stage frequency domain blind equalization for coherent pol-mux 16-QAM system with CD prediction and dual-mode adaptive algorithm
Publisher: IEEE
Date: 09-2012
A tight binding and $$\overrightarrow{{\boldsymbol{k}}}\cdot \overrightarrow{{\boldsymbol{p}}}$$ study of monolayer stanene
Publisher: Springer Science and Business Media LLC
Date: 21-09-2017
DOI: 10.1038/S41598-017-12281-Y
Abstract: Stanene is a single layer of tin atoms which has been discovered as an emerging material for quantum spin Hall related applications. In this paper, we present an accurate tight-binding model for single layer stanene near the Fermi level. We parameterized the onsite and hopping energies for the nearest, second nearest, and third nearest neighbor tight-binding method, both without and with spin orbital coupling. We derived the analytical solution for the $$\\overrightarrow{{\\boldsymbol{\\Gamma }}}$$ Γ → and $$\\overrightarrow{{\\boldsymbol{K}}}$$ K → points and numerically investigated the buckling effect on the material electronic properties. In these points of the reciprocal space, we also discuss a corresponding $$\\overrightarrow{{\\boldsymbol{k}}}\\cdot \\overrightarrow{{\\boldsymbol{p}}}$$ k → ⋅ p → description, obtaining the value of the $$\\overrightarrow{{\\boldsymbol{k}}}\\cdot \\overrightarrow{{\\boldsymbol{p}}}$$ k → ⋅ p → parameters both analytically from the tight-binding ones, and numerically, fitting the ab-initio dispersion relations. Our models provide a foundation for large scale atomistic device transport calculations.
A graphene nanoribbon neuro-sensor for glycine detection and imaging
Publisher: AIP Publishing
Date: 02-06-2014
DOI: 10.1063/1.4880744
Abstract: Glycine acts as a neurotransmitter in the Central Nervous System (CNS) and plays a vital role in processing of motor and sensory information that control movement, vision, and audition. Glycine detection and imaging can lead to a greater understanding of how this information is processed in the CNS. Here, we present a neuro-sensor for the detection and imaging of Glycine molecules, based on a zigzag Graphene Nanoribbon device structure. An energetically stable Nitrogen Vacancy (NV) center is introduced in the device to enable its use in neuronal imaging applications. We demonstrate, by using the Density Functional Theory and Nonequilibrium Green's Function method, that the device detects the attachment of a single Glycine molecule to its edges by significant changes in its conductance. The attachment of Glycine induces current channels around the NV center increasing the current flow through the device. In absence of Glycine, the presence of the NV center suppresses current flow through the device, significantly reducing its power consumption, and allowing for its use in proximity of living neuron cells.
High-speed reconfigurable free-space card-to-card optical interconnects
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 10-2012
Direct Electrohydrodynamic Patterning of High-Performance All Metal Oxide Thin-Film Electronics
Publisher: American Chemical Society (ACS)
Date: 03-12-2019
Abstract: In this paper, we propose a scalable approach toward all-printed high-performance metal oxide thin-film transistors (TFTs), using a high-resolution electrohydrodynamic (EHD) printing process. Direct EHD micropatterning of metal oxide TFTs is based on erse precursor solutions to form semiconducting materials (In
A fully flexible stimulator using 65 nm CMOS process for 1024-electrode epi-retinal prosthesis
Publisher: IEEE
Date: 09-2009
Investigating enhanced thermoelectric performance of graphene-based nano-structures
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8NR00134K
Abstract: The thermoelectric performance of graphene nano-ribbons are investigated providing a route to enhance thermoelectric performance through nano-structuring.
A microstrip antenna for 60-GHz CMOS transceiver system in a package
Publisher: IEEE
Date: 05-2008
Gapped graphene nanopores with enhanced operating current and sensitivity for biological and chemical sensing applications
Publisher: AIP Publishing
Date: 21-07-2014
DOI: 10.1063/1.4890414
Abstract: Graphene nanopores (GNPs) hold great promise as sensors for biological and chemical sensing applications because of their potential in achieving ultra-high sensitivity and sizeable operating currents. However, it remains a challenging task to realize the full potential of GNP sensors in real biological and chemical environment because of strong noise and interference. Here we propose a new GNP based sensor that consists of two conduction units. Due to the opening of additional conductive channels and enhanced transmission pathways around the nanopore, the proposed gapped-GNP structure is shown to operate with significantly improved conductivity and sensitivity over standard GNPs. The proposed device shows promise in dealing with noise and interference observed in practice.
60 GHz double-balanced up-conversion mixer on 130 nm CMOS technology
Publisher: Institution of Engineering and Technology (IET)
Date: 2008
DOI: 10.1049/EL:20080718
High-speed indoor optical wireless communication system with a steering mirror based up-link receiver
Publisher: OSA
Date: 2012
Self-Organized Nanostructure Modified Microelectrode for Sensitive Electrochemical Glutamate Detection in Stem Cells-Derived Brain Organoids
Publisher: MDPI AG
Date: 05-02-2018
DOI: 10.3390/BIOS8010014
Monolayer MoS2 self-switching diodes
Publisher: AIP Publishing
Date: 27-01-2016
DOI: 10.1063/1.4940707
Abstract: This paper presents a new molybdenum disulphide (MoS2) nanodevice that acts as a two-terminal field-effect rectifier. The device is an atomically-thin two-dimensional self-switching diode (SSD) that can be realized within a single MoS2 monolayer with very minimal process steps. Quantum simulation results are presented confirming the device's operation as a diode and showing strong non-linear I-V characteristics. Interestingly, the device shows p-type behavior, in which conduction is dominated by holes as majority charge carriers and the flow of reverse current is enhanced, while the flow of forward current is suppressed, in contrast to monolayer graphene SSDs, which behave as n-type devices. The presence of a large bandgap in monolayer MoS2 results in strong control over the channel, showing complete channel pinch-off in forward conduction, which was confirmed with transmission pathways plots. The device exhibited large leakage tunnelling current through the insulating trenches, which may have been due to the lack of passivation nevertheless, reverse current remained to be 6 times higher than forward current, showing strong rectification. The effect of p-type substitutional channel doping of sulphur with phosphorus was investigated and showed that it greatly enhances the performance of the device, increasing the reverse-to-forward current rectification ratio more than an order of magnitude, up to a value of 70.
High-speed optical wireless communication system with steering-mirror based receiver for personal area applications
Publisher: IEEE
Date: 09-2012
Experimental demonstration of high-speed reconfigurable card-to-card optical interconnects with broadcast capability
Publisher: IEEE
Date: 05-2013
Ultra-broadband indoor optical wireless communication system with multimode fiber
Publisher: The Optical Society
Date: 27-04-2012
DOI: 10.1364/OL.37.001514
All-graphene planar double barrier resonant tunneling diodes
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2014
Flip-chip interconnection effects on 60-GHz microstrip antenna performance
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2009
Contactless electronic transport in a bio-molecular junction
Publisher: AIP Publishing
Date: 28-07-2014
DOI: 10.1063/1.4891857
Abstract: Molecular electronics hold promise for next generation ultra-low power, nano-scale integrated electronics. The main challenge in molecular electronics is to make a reliable interface between molecules and metal electrodes. Interfacing metals and molecules detrimentally affects the characteristics of nano-scale molecular electronic devices. It is therefore essential to investigate alternative arrangements such as contact-less tunneling gaps wherever such configurations are feasible. We conduct ab initio density functional theory and non-equilibrium Green's functions calculations to investigate the transport properties of a biocompatible glycine molecular junction. By analyzing the localized molecular orbital energy distributions and transmission probabilities in the transport-gap, we find a glycine molecule confined between two gold electrodes, without making a contact, is energetically stable and possesses high tunneling current resembling an excellent ohmic-like interface.
A complete 256-electrode retinal prosthesis chip
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 03-2014
Development of silicon optics for an integrated micro-optical system-on-a-chip
Publisher: SPIE
Date: 07-12-2013
DOI: 10.1117/12.2033695
Experimental demonstration of a full-duplex indoor optical wireless communication system
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 02-2012
Distributed source localization in wireless sensor networks
Publisher: IEEE
Date: 07-2010
Coupling invariant inductive link for wireless power delivery to a retinal prosthesis
Publisher: IEEE
Date: 07-2013
A low power MICS band phase-locked loop for high resolution retinal prosthesis
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2013
Erratum: Response to Belgard et al.
Publisher: Springer Science and Business Media LLC
Date: 18-03-2014
DOI: 10.1038/MP.2014.27
A fully integrated 200 μw, 40pJ/b wireless transmitter for implanted medical devices and neural prostheses
Publisher: IEEE
Date: 07-2013
100 Gb/s 1024-way-split 100-km long-reach PON using spectrally efficient frequency interleaved directly detected optical OFDM
Publisher: IEEE
Date: 08-2011
Fully Solution-Processed Transparent Artificial Neural Network Using Drop-On-Demand Electrohydrodynamic Printing
Publisher: American Chemical Society (ACS)
Date: 22-04-2019
Abstract: Artificial neural networks (ANN), deep learning, and neuromorphic systems are exciting new processing architectures being used to implement a wide variety of intelligent and adaptive systems. To date, these architectures have been primarily realized using traditional complementary metal-oxide-semiconductor (CMOS) processes or otherwise conventional semiconductor fabrication processes. Thus, the high cost associated with the design and fabrication of these circuits has limited the broader scientific community from applying new ideas, and arguably, has slowed research progress in this exciting new area. Solution-processed electronics offer an attractive option for providing low-cost rapid prototyping of neuromorphic devices. This article proposes a novel, wholly solution-based process used to produce low-cost transparent synaptic transistors capable of emulating biological synaptic functioning and thus used to construct ANN. We have demonstrated the fabrication process by constructing an ANN that encodes and decodes a 100 × 100 pixel image. Here, the synaptic weights were configured to achieve the desired image processing functions.
Live demonstration: An associative capacitive network based on nanoscale complementary resistive switches
Publisher: IEEE
Date: 06-2014
High-speed optical wireless communications in personal area networks
Publisher: IEEE
Date: 11-2014
A subthreshold down converter optimized for super-low-power applications in MICS band
Publisher: IEEE
Date: 11-2011
High-speed reconfigurable free-space optical interconnects with carrierless-amplitude-phase modulation and space-time-block code
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 15-01-2019
Single carrier QPSK and 16 QAM system demonstration using frequency domain equalization and training sequences
Publisher: IEEE
Date: 07-2012
An ultra low power digital receiver architecture for biomedical applications
Publisher: IEEE
Date: 11-2011
Digital signal processing for training-aided coherent optical single-carrier frequency-domain equalization systems
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 15-12-2014
Scalable and Spectrally Efficient Long-Reach Optical Access Networks Employing Frequency Interleaved Directly Detected Optical OFDM
Publisher: The Optical Society
Date: 31-10-2011
Design of a compact ultra wideband balanced-to-balanced power divider/combiner
Publisher: IEEE
Date: 11-2013
A flexible electrode driver using 65 nm CMOS process for 1024-electrode Epi-retinal prosthesis
Publisher: IEEE
Date: 2010
Impact of crosstalk on indoor WDM optical wireless communication systems
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2012
Implementation of a gigabit per second millimetre wave transceiver on CMOS
Publisher: IEEE
Date: 08-2007
Full-duplex reconfigurable card-to-card optical interconnects based on hybrid free-space and multi-mode fiber propagation
Publisher: IEEE
Date: 04-2015
Frequency domain multi-modulus blind equalization for coherent 16 QAM polarization-multiplexed system
Publisher: IEEE
Date: 07-2012
Graphene nanopore field effect transistors
Publisher: AIP Publishing
Date: 11-07-2014
DOI: 10.1063/1.4889755
Abstract: Graphene holds great promise for replacing conventional Si material in field effect transistors (FETs) due to its high carrier mobility. Previously proposed graphene FETs either suffer from low ON-state current resulting from constrained channel width or require complex fabrication processes for edge-defecting or doping. Here, we propose an alternative graphene FET structure created on intrinsic metallic armchair-edged graphene nanoribbons with uniform width, where the channel region is made semiconducting by drilling a pore in the interior, and the two ends of the nanoribbon act naturally as connecting electrodes. The proposed GNP-FETs have high ON-state currents due to seamless atomic interface between the channel and electrodes and are able to be created with arbitrarily wide ribbons. In addition, the performance of GNP-FETs can be tuned by varying pore size and ribbon width. As a result, their performance and fabrication process are more predictable and controllable in comparison to schemes based on edge-defects and doping. Using first-principle transport calculations, we show that GNP-FETs can achieve competitive leakage current of ∼70 pA, subthreshold swing of ∼60 mV/decade, and significantly improved On/Off current ratios on the order of 105 as compared with other forms of graphene FETs.
Graphene field effect nanopore glycine detector
Publisher: IEEE
Date: 08-2014
A Silk Fibroin Bio-Transient Solution Processable Memristor
Publisher: Springer Science and Business Media LLC
Date: 07-11-2017
DOI: 10.1038/S41598-017-15395-5
Abstract: Today’s electronic devices are fabricated using highly toxic materials and processes which limits their applications in environmental sensing applications and mandates complex encapsulation methods in biological and medical applications. This paper proposes a fully resorbable high density bio-compatible and environmentally friendly solution processable memristive crossbar arrays using silk fibroin protein which demonstrated bipolar resistive switching ratio of 10 4 and possesses programmable device lifetime characteristics before the device gracefully bio-degrades, minimizing impact to environment or to the implanted host. Lactate dehydrogenase assays revealed no cytotoxicity on direct exposure to the fabricated device and support their environmentally friendly and biocompatible claims. Moreover, the correlation between the oxidation state of the cations and their tendency in forming conductive filaments with respect to different active electrode materials has been investigated. The experimental results and the numerical model based on electro-thermal effect shows a tight correspondence in predicting the memristive switching process with various combinations of electrodes which provides insight into the morphological changes of conductive filaments in the silk fibroin films.
On orientations of directional antennas in wireless sensor network
Publisher: IEEE
Date: 2008
Design of 120:1 frequency divider for a 12.6 GHz phase-locked loop
Publisher: IEEE
Date: 06-2014
Performance of high-speed reconfigurable free-space card-to-card optical interconnects under air turbulence
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2013
An active 38 GHz differential power divider for automotive radar systems in 65-nm CMOS
Publisher: IEEE
Date: 06-2014
Feasibility of energy-autonomous wireless microsensors for biomedical applications: Powering and communication
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2015
Response to Robinson et al.
Publisher: Springer Science and Business Media LLC
Date: 10-03-2015
DOI: 10.1038/MP.2015.15
Design of a capacitive DAC mismatch calibrator for split SAR ADC in 65 nm CMOS
Publisher: IEEE
Date: 11-2013
Ultra-broadband and low-loss optical power splitter based on tapered silicon waveguides
Publisher: IEEE
Date: 04-2015
Modeling and Estimating Simulated DNA Nanopore Translocation Signals
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2013
A super low power MICS band receiver in 65 nrn CMOS for high resolution epi-retinal prosthesis
Publisher: IEEE
Date: 10-2009
Complex Permittivity Measurements in 1-30 GHz Using a MEMS Probe
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2015
Non-equilibrium tunneling in zigzag graphene nanoribbon break-junction results in spin filtering
Publisher: AIP Publishing
Date: 02-2016
DOI: 10.1063/1.4940018
Abstract: Spintronic devices promise new faster and lower energy-consumption electronic systems. Graphene, a versatile material and candidate for next generation electronics, is known to possess interesting spintronic properties. In this paper, by utilizing density functional theory and non-equilibrium green function formalism, we show that Fano resonance can be generated by introducing a break junction in a zigzag graphene nanoribbon (ZGNR). Using this effect, we propose a new spin filtering device that can be used for spin injection. Our theoretical results indicate that the proposed device could achieve high spin filtering efficiency (over 90%) at practical fabrication geometries. Furthermore, our results indicate that the ZGNR break junction lattice configuration can dramatically affect spin filtering efficiency and thus needs to be considered when fabricating real devices. Our device can be fabricated on top of spin transport channel and provides good integration between spin injection and spin transport.
Vertical Nanowire Electrode Arrays as Novel Electrochemical Label‐Free Immunosensors
Publisher: Wiley
Date: 11-02-2015
Abstract: A new method for the fabrication of a label-free electrochemical immunosensor based on vertical nanowires (VNWs) is proposed. The VNWs are functionalized to detect antibodies against a major astrocytic structural protein component, glial fibrillary acidic protein (GFAP). It is revealed that the interaction of GFAP-antibody with functionalized VNWs leads to a clear change in device conductance and the corresponding capacitance.
Pathway-wide association study identifies five shared pathways associated with schizophrenia in three ancestral distinct populations
Publisher: Springer Science and Business Media LLC
Date: 21-02-2017
DOI: 10.1038/TP.2017.8
Abstract: Genome-wide association studies have confirmed the polygenic nature of schizophrenia and suggest that there are hundreds or thousands of alleles associated with increased liability for the disorder. However, the generalizability of any one allelic marker of liability is remarkably low and has bred the notion that schizophrenia may be better conceptualized as a pathway(s) disorder. Here, we empirically tested this notion by conducting a pathway-wide association study (PWAS) encompassing 255 experimentally validated Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways among 5033 in iduals diagnosed with schizophrenia and 5332 unrelated healthy controls across three distinct ethnic populations European-American (EA), African-American (AA) and Han Chinese (CH). We identified 103, 74 and 87 pathways associated with schizophrenia liability in the EA, CH and AA populations, respectively. About half of these pathways were uniquely associated with schizophrenia liability in each of the three populations. Five pathways (serotonergic synapse, ubiquitin mediated proteolysis, hedgehog signaling, adipocytokine signaling and renin secretion) were shared across all three populations and the single-nucleotide polymorphism sets representing these five pathways were enriched for single-nucleotide polymorphisms with regulatory function. Our findings provide empirical support for schizophrenia as a pathway disorder and suggest schizophrenia is not only a polygenic but likely also a poly-pathway disorder characterized by both genetic and pathway heterogeneity.
A 65nm CMOS low-power, low-voltage bandgap reference with using self-biased composite cascode opamp
Publisher: ACM
Date: 18-08-2010
4 × 12.5 Gb/s WDM optical wireless communication system for indoor applications
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 07-2011
Experimental demonstration of free-space based 120 Gb/s reconfigurable card-to-card optical interconnects
Publisher: The Optical Society
Date: 30-09-2014
DOI: 10.1364/OL.39.005717
Design of the internal DAC in SAR ADCs
Publisher: IEEE
Date: 08-2012
Biological sensing using frequency based interrogation of functionalized silicon nanowires
Publisher: IEEE
Date: 10-2011
Letter: improved parsimony of genetic risk scores for coeliac disease through refined HLA modelling
Publisher: Wiley
Date: 18-02-2021
DOI: 10.1111/APT.16263
Data-aided chromatic dispersion estimation for polarization multiplexed optical systems
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 10-2012
Free-space optics for high-speed reconfigurable card-to-card optical interconnects
Publisher: SPIE
Date: 18-09-2013
DOI: 10.1117/12.2022807
High-speed indoor optical wireless communication system with single channel imaging receiver
Publisher: The Optical Society
Date: 27-03-2012
DOI: 10.1364/OE.20.008442
Asymmetrically-gated graphene self-switching diodes as negative differential resistance devices
Publisher: Royal Society of Chemistry (RSC)
Date: 2014
DOI: 10.1039/C4NR00112E
Abstract: In an asymmetrically-gated graphene self-switching diode the quantum tunnelling current is used to control a much larger channel conduction current, resulting in a very pronounced NDR effect.
Predicting the diagnosis of autism spectrum disorder using gene pathway analysis
Publisher: Springer Science and Business Media LLC
Date: 11-09-2012
DOI: 10.1038/MP.2012.126
Balanced heterodyne architecture for improving the noise performance of electro-optic probing systems
Publisher: IEEE
Date: 10-2013
Wireless power delivery for retinal prostheses
Publisher: IEEE
Date: 08-2011
Optical performance monitoring for OFDM using low bandwidth coherent receivers
Publisher: The Optical Society
Date: 11-12-2012
DOI: 10.1364/OE.20.028724
Rapid Detection of HLA-B*57:01-Expressing Cells Using a Label-Free Interdigitated Electrode Biosensor Platform for Prevention of Abacavir Hypersensitivity in HIV Treatment
Publisher: MDPI AG
Date: 14-08-2019
DOI: 10.3390/S19163543
Abstract: Pre-treatment screening of in iduals for human leukocyte antigens (HLA) HLA-B*57:01 is recommended for the prevention of life-threatening hypersensitivity reactions to abacavir, a drug widely prescribed for HIV treatment. However, the implementation of screening in clinical practice is hindered by the slow turnaround time and high cost of conventional HLA genotyping methods. We have developed a biosensor platform using interdigitated electrode (IDE) functionalized with a monoclonal antibody to detect cells expressing HLA-B*57:01. This platform was evaluated using cell lines and peripheral blood mononuclear cells expressing different HLA-B alleles. The functionalized IDE sensor was able to specifically capture HLA-B*57:01 cells, resulting in a significant change in the impedance magnitude in 20 min. This IDE platform has the potential to be further developed to enable point-of-care HLA-B*57:01 screening.
Microring-based wavelength-selective reflection/rejection filter with independently determined bandwidth and reflectance
Publisher: IEEE
Date: 09-2013
Gigabit optical wireless communication system for indoor applications
Publisher: IEEE
Date: 12-2010
Experimental demonstration of high-speed free-space reconfigurable card-to-card optical interconnects
Publisher: The Optical Society
Date: 30-01-2013
DOI: 10.1364/OE.21.002850
A 60-GHz Double-Balanced Gilbert Cell Down-Conversion Mixer on 130-nm CMOS
Publisher: IEEE
Date: 06-2007
High Performance Graphene Nano-ribbon Thermoelectric Devices by Incorporation and Dimensional Tuning of Nanopores
Publisher: Springer Science and Business Media LLC
Date: 17-06-2015
DOI: 10.1038/SREP11297
Abstract: Thermoelectric properties of Graphene nano-ribbons (GNRs) with nanopores (NPs) are explored for a range of pore dimensions in order to achieve a high performance two-dimensional nano-scale thermoelectric device. We reduce thermal conductivity of GNRs by introducing pores in them in order to enhance their thermoelectric performance. The electrical properties (Seebeck coefficient and conductivity) of the device usually degrade with pore inclusion however, we tune the pore to its optimal dimension in order to minimize this degradation, enhancing the overall thermoelectric performance (high ZT value) of our device. We observe that the side channel width plays an important role to achieve optimal performance while the effect of pore length is less pronounced. This result is consistent with the fact that electronic conduction in GNRs is dominated along its edges. Ballistic transport regime is assumed and a semi-empirical method using Huckel basis set is used to obtain the electrical properties, while the phononic system is characterized by Tersoff empirical potential model. The proposed device structure has potential applications as a nanoscale local cooler and as a thermoelectric power generator.
5–75 GHz common-gate subharmonic mixer in 65 nm CMOS
Publisher: Institution of Engineering and Technology (IET)
Date: 2010
DOI: 10.1049/EL.2010.1166
Indoor WDM optical wireless communication system with single channel imaging receiver
Publisher: IEEE
Date: 07-2012
Applying implicit training to polarization-division-multiplexed coherent optical systems
Publisher: The Optical Society
Date: 20-08-2013
DOI: 10.1364/OE.21.020187
Statistical moments-based OSNR monitoring for coherent optical systems
Publisher: The Optical Society
Date: 19-07-2012
DOI: 10.1364/OE.20.017711
High-speed indoor optical wireless communication system employing a silicon integrated photonic circuit
Publisher: The Optical Society
Date: 25-06-2018
DOI: 10.1364/OL.43.003132
Gigabit optical wireless communication system for indoor applications
Publisher: SPIE
Date: 26-12-2011
DOI: 10.1117/12.887955
Provisioning in-house mobility for FTTH customers by incorporating modifications in optical network unit (ONU)
Publisher: IEEE
Date: 10-2011
Tunneling-Limited Thermoelectric Transport in Carbon Nanotube Networks Embedded in Poly(dimethylsiloxane) Elastomer
Publisher: American Chemical Society (ACS)
Date: 15-03-2019
High-speed free-space based reconfigurable card-to-card optical interconnects with broadcast capability
Publisher: The Optical Society
Date: 20-06-2013
DOI: 10.1364/OE.21.015395
A charge-balanced 4-wire interface for the interconnections of biomedical implants
Publisher: IEEE
Date: 10-2013
Response to Belgard et al.
Publisher: Springer Science and Business Media LLC
Date: 14-01-2014
DOI: 10.1038/MP.2013.186
Micro-watt inductorless gm-boost LNA for biomedical implants
Publisher: IEEE
Date: 05-2013
120 Gb/s reconfigurable optical interconnect based on hybrid free-space and MMF propagations
Publisher: IEEE
Date: 05-0005
Closed-loop inductive link for wireless powering of a high density electrode array retinal prosthesis
Publisher: IEEE
Date: 09-2009
Ultrasensitive and label-free biosensor for the detection of Plasmodium falciparum histidine-rich protein II in saliva
Publisher: Springer Science and Business Media LLC
Date: 25-11-2019
DOI: 10.1038/S41598-019-53852-5
Abstract: Malaria elimination is a global public health priority. To fulfil the demands of elimination diagnostics, we have developed an interdigitated electrode sensor platform targeting the Plasmodium falciparum Histidine Rich Protein 2 ( Pf HRP2) protein in saliva s les. A protocol for frequency-specific Pf HRP2 detection in phosphate buffered saline was developed, yielding a sensitivity of 2.5 pg/mL based on change in impedance magnitude of the sensor. This protocol was adapted and optimized for use in saliva with a sensitivity of 25 pg/mL based on change in resistance. Further validation demonstrated detection in saliva spiked with Pf HRP2 from clinical isolates in 8 of 11 s les. With a turnaround time of ~2 hours, the label-free platform based on impedance sensors has the potential for miniaturization into a point-of-care diagnostic device for malaria elimination.
Detection of protein conformational changes with multilayer graphene nanopore sensors
Publisher: American Chemical Society (ACS)
Date: 19-09-2014
DOI: 10.1021/AM5040279
Abstract: Detecting conformational change in protein or peptide is imperative in understanding their dynamic function and diagnosing diseases. Existing techniques either rely on ensemble average that lacks the necessary sensitivity or require florescence labeling. Here we propose to discriminate between different protein conformations with multiple layers of graphene nanopore sensors by measuring the effect of protein-produced electrostatic potential (EP) on electric transport. Using conformations of the octapeptide Angiotensin II obtained through molecular dynamics simulations, we show that the EP critically depends on the geometries of constituent atoms and each conformation carries a unique EP signature. We then, using quantum transport simulations, reveal that these characteristic EP profiles cause distinctive modulation to electric charge densities of the graphene nanopores, leading to distinguishable changes in conductivity. Our results open the potential of label-free, single-molecule, and real-time detection of protein conformational changes.
Enhanced thermoelectric properties of engineered graphene nano-ribbons with nano-pores
Publisher: IEEE
Date: 08-2014
Graphene nanopores as negative differential resistance devices
Publisher: AIP Publishing
Date: 03-02-2015
DOI: 10.1063/1.4907265
Abstract: We present graphene nanopores as new negative differential resistance (NDR) devices, and study their quantum transport properties using non-equilibrium Green's function and the density functional tight binding method. The proposed device structure is created on intrinsic armchair-edged graphene nanoribbons with uniform widths, where the central scattering region has a nanopore in the interior, and the two ends of the nanoribbon act naturally as connecting electrodes. We show that nitrogen-passivated scattering regions generally result in pronounced NDR properties, while hydrogen-passivated ones do not. This NDR effect occurs at low bias voltages, below 1 V, and achieves extraordinarily high peak-to-valley current ratio, while still attaining very high peak current densities. In addition, very sharp current peaks in the μA range can occur in the I-V curves, and through varying structural dimensions of the proposed structure multiple NDR regions can be realized. These results suggest that the device has promising potential in applications such as high frequency oscillators, memory devices, and fast switches.
A CMOS track-and-hold circuit with beyond 30 GHz input bandwidth
Publisher: IEEE
Date: 12-2012
An analysis of electro-optic measurement of electric fields using Jones matrix formulation
Publisher: SPIE
Date: 30-11-2011
DOI: 10.1117/12.904488
Convergent evidence for mGluR5 in synaptic and neuroinflammatory pathways implicated in ASD
Publisher: Elsevier BV
Date: 05-2015
DOI: 10.1016/J.NEUBIOREV.2015.02.006
Abstract: The pathogenesis of Autism Spectrum Disorder (ASD), a serious neurodevelopmental disorder, is poorly understood. We review evidence for alterations in glutamatergic signalling in the aetiology of ASD, with a focus on the metabotropic glutamate receptor-5 (mGluR5). mGluR5 signalling is important for synapse formation, neuroplasticity and long term potentiation as well as neuroprotection and has been shown to have a regulatory role in neuroinflammation. Evidence for neuroinflammation in ASD is supported by increase in pro-inflammatory cytokines in the blood and cerebrospinal fluid (CSF) and increased number and activation of microglia in postmortem dorsolateral prefrontal cortex (DLPFC). mGlur5 signalling has also been shown to downregulate microglial activation. Therefore, we focus on mGluR5 as a potential unifying explanation for synapse alteration and neuroinflammation seen in ASD. Data from mGluR5 knockout mouse models, and syndromic and non syndromic forms of ASD are discussed in relation to how alterations in mGluR5 are associated with ASD symptoms. This review supports altered mGluR5 functioning as a convergent point in ASD pathogenesis and indicates more research is warranted into mGluR5 as a potential therapeutic target.
Moments-based OSNR monitoring for QPSK and QAM coherent optical systems
Publisher: IEEE
Date: 07-2012
Performance of reconfigurable free-space card-to-card optical interconnects under atmospheric turbulence
Publisher: IEEE
Date: 12-2012
A simple voltage reference with ultra supply independency
Publisher: IEEE
Date: 05-2012
Experimental demonstration of 3 × 3 10 Gb/s reconfigurable free space optical card-to-card interconnects
Publisher: The Optical Society
Date: 21-06-2012
DOI: 10.1364/OL.37.002553
Indoor gigabit optical wireless communication system for personal area networks
Publisher: IEEE
Date: 11-2010
High Performance and High Yield Solution Processed IGZO Thin Film Transistors Fabricated with Low‐Temperature Annealed Hafnium Dioxide Gate Dielectric
Publisher: Wiley
Date: 11-08-2023
Abstract: Solution‐processed microelectronics offer advantages, including cost‐effectiveness, higher energy efficiency, and compatibility with rapid prototyping compared to their counterparts fabricated through traditional semiconductor manufacturing processes. Unfortunately, solution‐processed transistors exhibit wide performance variability and low yield. In this work, a solution‐processed transparent indium gallium zinc oxide (IGZO) thin film transistor with a low temperature‐annealed hafnium oxide dielectric layer is described. Post‐annealing temperatures for the sol–gel hafnium dioxide thin film are reduced to below 200 °C, significantly expanding the range of substrates on which the metal oxide dielectric can be deposited. The fabricated devices exhibit excellent characteristics with high field‐effect mobilities of over 85 cm 2 V −1 s −1 , along with low subthreshold swing below 140 mV dec −1 , high on/off ratios, and near‐zero threshold voltages when operating stably at low‐operating voltages of 2 V. The solution processed transparent hafnium dioxide gate dielectric IGZO transistors are shown to exhibit comparatively significantly lower device variation and high yield, allowing for the reproducible fabrication of large‐area and transparent solution processed microelectronics systems.
Fast wavelength-switchable hybrid laser for energy-efficient optical interconnect
Publisher: IEEE
Date: 05-2014
Feasibility study of molecular memory device based on DNA using methylation to store information
Publisher: AIP Publishing
Date: 11-07-2016
DOI: 10.1063/1.4954219
Abstract: DNA, because of its robustness and dense information storage capability, has been proposed as a potential candidate for next-generation storage media. However, encoding information into the DNA sequence requires molecular synthesis technology, which to date is costly and prone to synthesis errors. Reading the DNA strand information is also complex. Ideally, DNA storage will provide methods for modifying stored information. Here, we conduct a feasibility study investigating the use of the DNA 5-methylcytosine (5mC) methylation state as a molecular memory to store information. We propose a new 1-bit memory device and study, based on the density functional theory and non-equilibrium Green's function method, the feasibility of electrically reading the information. Our results show that changes to methylation states lead to changes in the peak of negative differential resistance which can be used to interrogate memory state. Our work demonstrates a new memory concept based on methylation state which can be beneficial in the design of next generation DNA based molecular electronic memory devices.
A 60-GHz Double-Balanced Mixer for Direct Up-Conversion Transmitter on 130-nm CMOS
Publisher: IEEE
Date: 10-2008
Enhanced tree routing for wireless sensor networks
Publisher: Elsevier BV
Date: 05-2009
A prototype 64-electrode stimulator in 65 nm CMOS process towards a high density epi-retinal prosthesis
Publisher: IEEE
Date: 08-2011
IEEE 802.15.3C medium access controller throughput for phased array systems
Publisher: IEEE
Date: 2007
A super low power MICS band receiver front-end down converter on 65 nm CMOS
Publisher: IEEE
Date: 10-2010
A flexible biphasic pulse generating and accurate charge balancing stimulator with a 1μW neural recording amplifier
Publisher: IEEE
Date: 05-2013
Cross-ethnicity tagging SNPs for HLA alleles associated with adverse drug reaction
Publisher: Springer Science and Business Media LLC
Date: 10-08-2018
DOI: 10.1038/S41397-018-0039-Z
Abstract: Reduction of adverse drug reaction (ADR) incidence through screening of predisposing human leucocyte antigen (HLA) alleles is a promising approach for many widely used drugs. However, application of these associations has been limited by the cost burden of HLA genotyping. Use of single nucleotide polymorphisms (SNPs) that can approximate ('tag') HLA alleles of interest has been proposed as a cost-effective and simple alternative to conventional genotyping. However, most reported SNP tags have not been validated and there is concern regarding clinical utility of this approach due to tagging inconsistency across different populations. We assess the ability of 67 previously reported and 378 novel tagging SNPs, identified here in 5 HLA reference panels, to tag 15 ADR-associated HLA alleles in a panel of 955 ethnically erse s les. Tags for 8 HLA alleles of interest were identified with 100% sensitivity and >95% specificity. These SNPs may act as a reliable genotyping approach for the routine screening of patients, without the need to account for patient ethnicity.
Graphene nanopores: Electronic transport properties and design methodology
Publisher: Royal Society of Chemistry (RSC)
Date: 2014
DOI: 10.1039/C3CP53777C
Abstract: Graphene nanopores (GNPs) hold great promise as building blocks for electronic circuitry and sensors for biological and chemical sensing applications. Methods to design graphene nanopores that achieve desirable conduction performance and sensing characteristics have not been previously described. Here we present a study of the quantum transport properties of GNPs created by drilling pores in armchair and zigzag graphene ribbons. For the first time, our study reveals that the quantum transmission spectra of GNPs are highly tunable and GNPs with specific transport properties can be produced by properly designing pore shapes. Our investigation shows that the biological sensing capabilities of GNPs are transmission spectrum dependent, can vary dramatically, and are critically dependent on pore geometry. Our study provides design guidelines for creating graphene nanopores with specific transport properties to meet the needs of erse applications and for developing sensitive biological/chemical sensors with required performance characteristics.
On the analysis of using 3-coil wireless power transfer system in retinal prosthesis
Publisher: IEEE
Date: 08-2014
In-house seamless and transparent internet on the move through cordless access to FTTH
Publisher: IEEE
Date: 09-2012
PMD monitoring in 16-QAM coherent optical system using golay sequences
Publisher: IEEE
Date: 07-2012
Circular Bragg grating mirror with high reflectance and wide bandwidth for TM-polarized waves
Publisher: IEEE
Date: 05-2014
Application-driven Design
Publisher: Springer Berlin Heidelberg
Date: 2006
Wireless technologies for closed-loop retinal prostheses
Publisher: IOP Publishing
Date: 23-10-2009
DOI: 10.1088/1741-2560/6/6/065004
Abstract: In this paper, we discuss various technologies needed to develop retinal prostheses with wireless power and data telemetry operation. In addition to the need to communicate with the implanted device, supply of power to the retinal prosthesis is especially difficult. This is because, in the implanted state, the device is not fixed in position due to constant motion of the eye. Furthermore, a retinal prosthesis incorporating a high density electrode array of more than 1000 electrodes is expected to consume approximately 45 mW of power and require 300 kbps of image and stimulation data. The front end of the wireless power and data transmission, the antenna, needs to be small compared to the size of the eye. Also, the wireless module is expected to operate in the reactive near-field region due to small separation between the transmit and receive antennas compared to their size and corresponding operating wavelength. An inductive link is studied as a means to transfer power and for data telemetry between the implant and external unit. In this work, the use of integrated circuit and microfabrication technologies for implementing inductive links is discussed. A closed-loop approach is taken to improve performance and reach optimum operation condition. Design and simulation data are presented as the basis for development of viable wireless module prototypes.
High-speed reconfigurable card-to-card optical interconnects based on hybrid free-space and multi-mode fiber propagations
Publisher: The Optical Society
Date: 10-12-2013
DOI: 10.1364/OE.21.031166
Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells.
Publisher: Springer Science and Business Media LLC
Date: 12-01-2018
DOI: 10.1038/S41598-017-19093-0
Abstract: The dorsal root ganglia (DRG) consist of a multitude of sensory neuronal subtypes that function to relay sensory stimuli, including temperature, pressure, pain and position to the central nervous system. Our knowledge of DRG sensory neurons have been predominantly driven by animal studies and considerably less is known about the human DRG. Human embryonic stem cells (hESC) are valuable resource to help close this gap. Our previous studies reported an efficient system for deriving neural crest and DRG sensory neurons from hESC. Here we show that this differentiation system gives rise to heterogeneous populations of sensory neuronal subtypes as demonstrated by phenotypic and functional analyses. Furthermore, using microelectrode arrays the maturation rate of the hESC-derived sensory neuronal cultures was monitored over 8 weeks in culture, showing their spontaneous firing activities starting at about 12 days post-differentiation and reaching maximum firing at about 6 weeks. These studies are highly valuable for developing an in vitro platform to study the ersity of sensory neuronal subtypes found within the human DRG.
Flexible bandwidth DGD estimation for coherent optical OFDM system
Publisher: The Optical Society
Date: 22-10-2013
DOI: 10.1364/OE.21.025788
Development of an Ultrasensitive Impedimetric Immunosensor Platform for Detection of Plasmodium Lactate Dehydrogenase
Publisher: MDPI AG
Date: 29-05-2019
DOI: 10.3390/S19112446
Abstract: Elimination of malaria is a global health priority. Detecting an asymptomatic carrier of Plasmodium parasites to receive treatment is an important step in achieving this goal. Current available tools for detection of malaria parasites are either expensive, lacking in sensitivity for asymptomatic carriers, or low in throughput. We investigated the sensitivity of an impedimetric biosensor targeting the malaria biomarker Plasmodium lactate dehydrogenase (pLDH). Following optimization of the detection protocol, sensor performance was tested using phosphate-buffered saline (PBS), and then saliva s les spiked with pLDH at various concentrations. The presence of pLDH was determined by analyzing the sensor electrical properties before and after s le application. Through comparing percentage changes in impedance magnitude, the sensors distinguished pLDH-spiked PBS from non-spiked PBS at concentrations as low as 250 pg/mL (p = 0.0008). Percentage changes in impedance magnitude from saliva spiked with 2.5 ng/mL pLDH trended higher than those from non-spiked saliva. These results suggest that these biosensors have the potential to detect concentrations of pLDH up to two logs lower than currently available best-practice diagnostic tools. Successful optimization of this sensor platform would enable more efficient diagnosis of asymptomatic carriers, who can be targeted for treatment, contributing to the elimination of malaria.
Impact of background light induced shot noise in high-speed full-duplex indoor optical wireless communication systems
Publisher: The Optical Society
Date: 12-10-2011
DOI: 10.1364/OE.19.021321
Utility of Pan-Family Assays for Rapid Viral Screening: Reducing Delays in Public Health Responses During Pandemics
Publisher: Cold Spring Harbor Laboratory
Date: 26-05-2020
DOI: 10.1101/2020.05.24.20112318
Abstract: The SARS-CoV-2 pandemic has highlighted deficiencies in the testing capacity of many developed countries during the early stages of emerging pandemics. Here we describe the potential for pan-family viral assays to improve early accessibility of large-scale nucleic acid testing. Coronaviruses and SARS-CoV-2 were used as a case-study for investigating the utility of pan-family viral assays during the early stages of a novel pandemic. Specificity of a pan-coronavirus (Pan-CoV) assay for viral detection was assessed using the frequency of common human coronavirus (HCoV) species in key populations. A reported Pan-CoV assay was assessed to determine sensitivity to SARS-CoV-2 and 59 other coronavirus species. The resilience of the primer target regions of this assay to mutation was assessed in 8893 high quality SARS-CoV-2 genomes to predict ongoing utility during pandemic progression. Due to infection with common HCoV species, a Pan-CoV assay would return a false positive for as few as 1% of asymptomatic adults, but up to 30% of immunocompromised patients displaying symptoms of respiratory disease. Two of the four reported pan-coronavirus assays would have identified SARS-CoV-2 and we demonstrate that with small adjustments to the primers, these assays can accommodate novel variation observed in animal coronaviruses. The assay target region of one well established Pan-CoV assay is highly resistant to mutation compared to regions targeted by other widely applied SARS-CoV-2 RT-PCR assays. Pan-family assays have the potential to greatly assist management of emerging public health emergencies through prioritization of high-resolution testing or isolation measures, despite limitations in test specificity due to cross-reactivity with common pathogens. Targeting highly conserved genomic regions make pan-family assays robust and resilient to mutation of a given virus. This approach may be applicable to other viral families and has utility as part of a strategic stockpile of tests maintained to better contain spread of novel diseases prior to the widespread availability of specific assays.
An associative capacitive network based on nanoscale complementary resistive switches for memory-intensive computing
Publisher: Royal Society of Chemistry (RSC)
Date: 2013
DOI: 10.1039/C3NR00535F
Abstract: We report on the implementation of an Associative Capacitive Network (ACN) based on the nondestructive capacitive readout of two Complementary Resistive Switches (2-CRSs). ACNs are capable of performing a fully parallel search for Hamming distances (i.e. similarity) between input and stored templates. Unlike conventional associative memories where charge retention is a key function and hence, they require frequent refresh cycles, in ACNs, information is retained in a nonvolatile resistive state and normal tasks are carried out through capacitive coupling between input and output nodes. Each device consists of two CRS cells and no selective element is needed, therefore, CMOS circuitry is only required in the periphery, for addressing and read-out. Highly parallel processing, nonvolatility, wide interconnectivity and low-energy consumption are significant advantages of ACNs over conventional and emerging associative memories. These characteristics make ACNs one of the promising candidates for applications in memory-intensive and cognitive computing, switches and routers as binary and ternary Content Addressable Memories (CAMs) and intelligent data processing.
High-speed full-duplex optical wireless communication system with single channel imaging receiver for personal area networks
Publisher: Institute of Electronics, Information and Communications Engineers (IEICE)
Date: 2013
An integrated transformer balun for 60 GHz silicon RF IC design
Publisher: IEEE
Date: 07-2007
Design of co-planar waveguide-fed slot/patch antenna with wire bond for a 60-GHz complementary metal-oxide-semiconductor transceiver
Publisher: Institution of Engineering and Technology (IET)
Date: 2011
Frequency-domain blind equalization for long-haul coherent Pol-Mux 16-QAM system with CD prediction and dual-mode adaptive algorithm
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 10-2012
An interdigitated electrode biosensor platform for rapid HLA-B*15:02 genotyping for prevention of drug hypersensitivity
Publisher: Elsevier BV
Date: 07-2018
DOI: 10.1016/J.BIOS.2018.01.063
Abstract: Prevention of life threatening hypersensitivity reactions to carbamazepine is possible through pre-treatment screening of the associated HLA-B*15:02 risk allele. However, clinical implementation of screening is hindered by the high cost and slow turnaround of conventional HLA typing methods. We have developed an interdigitated electrode (IDE) biosensor platform utilizing loop mediated isothermal lification (LAMP) that can rapidly detect the HLA-B*15:02 allele. DNA lification is followed by solid-phase hybridization of LAMP licons to a DNA probe immobilized on the IDE sensor surface, resulting in a change in sensor impedance. The testing platform does not require DNA extraction or post- lification staining, achieving s le-to-answer in 1 h and 20 min. The platform was tested on 27 whole blood s les (14 HLA-B*15:02 positive and 13 negative) with sensitivity of 92.9% and specificity of 84.6% when applying a cutoff of impedance change. Based on these characters the LAMP-IDE platform has potential to be further developed into point-of-care use to help overcome barriers in HLA-B*15:02 screening.
Improved two-stage equalization for coherent Pol-Mux QPSK and 16-QAM systems
Publisher: The Optical Society
Date: 28-11-2012
DOI: 10.1364/OE.20.00B141
OFDM Versus Single Carrier Towards Spectrally Efficient 100 Gb/s Transmission With Direct Detection
Publisher: The Optical Society
Date: 27-09-2012
Rapid, Loop-Mediated Isothermal Amplification Detection of Celiac Disease Risk Alleles
Publisher: Elsevier BV
Date: 05-2018
DOI: 10.1016/J.JMOLDX.2018.01.005
Abstract: Human leukocyte antigen (HLA) genotyping has become a useful investigation in the diagnostic work-up of celiac disease (CD), with utility in risk stratification and screening. However, broad application of this technology has been hindered by the cost and time burden of conventional laboratory-based assays. We have developed and validated CD-loop-mediated isothermal lification (CD-LAMP), a LAMP assay, which enables rapid identification of the signature CD risk genotypes, HLA-DQ2.5, HLA-DQ8, HLA-DQ2.2, and HLA-DQA1*05. S le-to-answer is achieved in approximately 65 minutes without DNA purification, thermal cycling, or specialized analytical equipment. CD-LAMP genotyping of s les was 100% concordant with accredited pathology genotyping on a panel of 40 blood and 20 saliva s les. In a panel of 100 purified DNA s les, genotyping of the high-risk DQ2.5 genotype was 100% concordant with accredited pathology genotyping, with slightly reduced sensitivity for the DQ8 genotype (97.1%) and reduced specificity for the DQ8 (93.9%) and DQ2.2 (95.1%) genotypes. CD-LAMP results are easily visualized and instrument free through the addition of a DNA intercalating dye after lification. Combined with point-of-care antibody testing, CD-LAMP may enable immediate, confident CD diagnosis at a low cost in the clinical setting.
Design of hybrid resistive-capacitive DAC for SAR A/D converters
Publisher: IEEE
Date: 12-2012
Low‐Temperature Solution‐Processed Transparent QLED Using Inorganic Metal Oxide Carrier Transport Layers
Publisher: Wiley
Date: 15-09-2021
Abstract: Quantum dot light‐emitting diodes (QLEDs) represent an exciting new technology that has many desirable attributes when compared to existing organic LEDs (OLEDs) including increased brightness, contrast, and response time. Solution‐based fabrication approaches have the advantage of being able to produce large‐area electronic systems at reduced costs and critical in applications such as large display fabrication and electronics on curved surfaces including low‐profile augmented reality glasses. In this paper, for the first time, a fully solution‐processed transparent inorganic QLED is described. Traditional QLED fabrication methodologies require the use of air‐sensitive materials that make fabrication of these devices challenging and expensive. Instead of using air‐sensitive organic materials, in the approach, nickel oxide (NiO) is used as the hole transport layer and is deposited using a sol‐gel method. Copper doping of the NiO to reduce the turn‐on voltage of the QLED device is investigated. Importantly, the post‐annealing temperature of the sol‐gel process is below 275 °C, which permits the fabrication of QLEDs on a wide range of substrates. The experimental results are concordant with the COMSOL simulation data and demonstrate the feasibility of fabricating fully transparent inorganic QLED devices using a solution‐based process.
High-speed duplex optical wireless communication system for indoor personal area networks
Publisher: The Optical Society
Date: 17-11-2010
DOI: 10.1364/OE.18.025199
A flexible wide bandwidth electro-optic probing system using a recirculating frequency shifter
Publisher: IEEE
Date: 10-2014
High-speed optical wireless communication system for indoor applications
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2011
Ultra low power LNA design for biomedical implants
Publisher: IEEE
Date: 04-2013
Ultra-broadband optical wireless communication system with single channel imaging receiver and multi-mode fiber for personal area networks
Publisher: IEEE
Date: 09-2012
A compact silicon grating coupler based on hollow tapered spot-size converter
Publisher: Springer Science and Business Media LLC
Date: 07-02-2018
DOI: 10.1038/S41598-018-20875-3
Abstract: A new compact silicon grating coupler enabling fibre-to-chip light coupling at a minimized taper length is proposed. The proposed coupler, which incorporates a hollow tapered waveguide, converts the spot-size of optical modes from micro- to nano-scales by reducing the lateral dimension from 15 µm to 300 nm at a length equals to 60 µm. The incorporation of such a coupler in photonic integrated circuit causes a physical footprint as small as 81 µm × 15 µm with coupling efficiency and 3-dB coupling bandwidth as high as 72% and 69 nm respectively.
Recirculating frequency shifter-based hybrid electro-optic probing system with ultra-wide bandwidth
Publisher: Institute of Electronics, Information and Communications Engineers (IEICE)
Date: 2015
A low-power 5-75-GHz common-gate subharmonic mixer in 65-nm CMOS
Publisher: IEEE
Date: 2011
A microstrip antenna with flip-chip interconnect for millimetre wave transceiver on CMOS
Publisher: IEEE
Date: 07-2008
Quantum conductance of armchair graphene nanopores with edge impurities
Publisher: AIP Publishing
Date: 15-08-2013
DOI: 10.1063/1.4816335
Abstract: The quantum conductance of armchair graphene nanopores (aGNPs) with edge impurities is investigated using the tight-binding model and non-equilibrium Green's function method. We find that aGNPs are particularly interesting since their transmission spectra can be easily tuned by pore-edge shaping to produce a variety of electronic transport characteristics. We first examine the local density of states at in idual impurity sites. We then study the quantum conductance of aGNPs with various transmission spectra in response to perturbations to on-site energies and hopping coefficients of edge atoms. Insights into transport properties of aGNPs are provided and implications of these findings for designing aGNP devices in interconnection and sensing applications are discussed.
Indoor optical wireless localization system with height estimation for high-speed wireless communications in personal areas
Publisher: IEEE
Date: 09-2012
Detection of weak nano-biosensor signals corrupted by shot noise
Publisher: IEEE
Date: 08-2013
Data-aided OSNR estimation for QPSK and 16-QAM coherent optical system
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 10-2013
Silicon nanowire photodetector enhanced by a bow-tie antenna
Publisher: Springer Science and Business Media LLC
Date: 05-11-2013
Energy-aware small-scale optical networks
Publisher: IEEE
Date: 07-2012
Highly scalable neuromorphic hardware with 1-bit stochastic nano-synapses
Publisher: IEEE
Date: 06-2014
A single sensor based multispectral imaging camera using a narrow spectral band color mosaic integrated on the monochrome CMOS image sensor
Publisher: AIP Publishing
Date: 04-2020
DOI: 10.1063/1.5140215
Abstract: A multispectral image camera captures image data within specific wavelength ranges in narrow wavelength bands across the electromagnetic spectrum. Images from a multispectral camera can extract a additional information that the human eye or a normal camera fails to capture and thus may have important applications in precision agriculture, forestry, medicine, and object identification. Conventional multispectral cameras are made up of multiple image sensors each fitted with a narrow passband wavelength filter and optics, which makes them heavy, bulky, power hungry, and very expensive. The multiple optics also create an image co-registration problem. Here, we demonstrate a single sensor based three band multispectral camera using a narrow spectral band red–green–blue color mosaic in a Bayer pattern integrated on a monochrome CMOS sensor. The narrow band color mosaic is made of a hybrid combination of plasmonic color filters and a heterostructured dielectric multilayer. The demonstrated camera technology has reduced cost, weight, size, and power by almost n times (where n is the number of bands) compared to a conventional multispectral camera.
Erratum: High-speed indoor optical wireless communication system with single channel imaging receiver (Optics Express (2012) 20:8 (8442-8456 ))
Publisher: The Optical Society
Date: 23-10-2012
DOI: 10.1364/OE.20.025356
Indoor optical wireless localization system for high-speed personal area networks
Publisher: IEEE
Date: 07-2012
Ultra-broadband indoor full-duplex WDM optical wireless communication with multi-mode fiber
Publisher: IEEE
Date: 08-2011
A precise charge balancing and compliance voltage monitoring stimulator front-end for 1024-electrodes retinal prosthesis
Publisher: IEEE
Date: 08-2012
Distributed routing for signal detection in wireless sensor networks
Publisher: Elsevier BV
Date: 12-2013
A 400-μW 3-GHz comparator in 65-nm CMOS
Publisher: IEEE
Date: 11-2012
Enhanced performance for implicit training-aided coherent optical systems by self-interference removal
Publisher: Institution of Engineering and Technology
Date: 2013
DOI: 10.1049/CP.2013.1596
Identification of MIMO systems with sparse transfer function coefficients
Publisher: Springer Science and Business Media LLC
Date: 09-05-2012
All-Graphene Planar Self-Switching MISFEDs, Metal-Insulator-Semiconductor Field-Effect Diodes
Publisher: Springer Science and Business Media LLC
Date: 05-02-2014
DOI: 10.1038/SREP03983
Related Organisations
Related Funding Activities
Linkage Projects - Grant ID: LP160101475
Start Date: 07-2017
End Date: 07-2020
Amount: $330,000.00
Funder: Australian Research Council
View Funded ActivityLinkage Infrastructure, Equipment And Facilities - Grant ID: LE130100128
Start Date: 2013
End Date: 06-2015
Amount: $670,000.00
Funder: Australian Research Council
View Funded ActivityLinkage Projects - Grant ID: LP120100706
Start Date: 11-2012
End Date: 12-2016
Amount: $111,302.00
Funder: Australian Research Council
View Funded ActivityDiscovery Projects - Grant ID: DP170100363
Start Date: 03-2017
End Date: 03-2021
Amount: $452,000.00
Funder: Australian Research Council
View Funded ActivityLinkage Infrastructure, Equipment And Facilities - Grant ID: LE120100124
Start Date: 01-2012
End Date: 10-2013
Amount: $300,000.00
Funder: Australian Research Council
View Funded ActivityLinkage Infrastructure, Equipment And Facilities - Grant ID: LE160100203
Start Date: 2016
End Date: 12-2016
Amount: $420,000.00
Funder: Australian Research Council
View Funded ActivityLinkage Infrastructure, Equipment And Facilities - Grant ID: LE160100124
Start Date: 2016
End Date: 12-2016
Amount: $300,000.00
Funder: Australian Research Council
View Funded ActivityDiscovery Projects - Grant ID: DP140101967
Start Date: 2014
End Date: 12-2016
Amount: $303,000.00
Funder: Australian Research Council
View Funded ActivityLinkage Infrastructure, Equipment And Facilities - Grant ID: LE180100037
Start Date: 2018
End Date: 12-2018
Amount: $223,039.00
Funder: Australian Research Council
View Funded ActivityARC Centres Of Excellence - Grant ID: CE140100007
Start Date: 06-2014
End Date: 12-2021
Amount: $20,000,000.00
Funder: Australian Research Council
View Funded ActivityIndustrial Transformation Research Hubs - Grant ID: IH150100003
Start Date: 12-2015
End Date: 06-2022
Amount: $2,611,346.00
Funder: Australian Research Council
View Funded Activity