Website
http://dataportal.arc.gov.au/NCGP/API/grants/LE180100179
Funding Status
Closed
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Funded Activity Summary
Automated high resolution and high contrast cryo -TEM for three-dimensional structural biology. This project aims to establish a facility in automated, single-particle cryo-TEM and cryo-TEM tomography (Titan Krios) that will enable atomic and molecular structure research and three-dimensional subcellular and cellular imaging. The project will span all multiscale cryo-TEM modalities from the visualisation of cells, membranes and macromolecular complexes, through to near-atomic-resolution protein structure determination. Cryo-single particle analysis and tomography are recognised as revolutionary technologies in molecular structural biology and powerful enablers of future ground-breaking discovery. The project will deliver significant competitive advantage for Australia in leading-edge structure-based research, drug discovery, new opportunities for applied research and development, and showcasing science to the public.Funded Activity Details
Start Date: 03-2018
End Date: 12-2019
Funding Scheme: Linkage Infrastructure, Equipment and Facilities
Funding Amount: $3,189,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling) | Macromolecular and Materials Chemistry not elsewhere classified
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Chemical Sciences | Scientific Instruments | Expanding Knowledge in the Biological Sciences |
