Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP190100766
Funding Status
Active
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Funded Activity Summary
Whole-genome multivariate reaction norm model for complex traits. This project aims to develop a multivariate whole-genome genotype-covariate correlation and interaction model that can be applied to a wide range of existing genome-wide association study (GWAS) datasets. Genotype-covariate correlation and interaction (GCCI) are fundamental in biology but there is no standard approach to disentangle interaction from correlation in the whole-genome analyses. This project will address the key feature in biology, which relates to dissecting the complex mechanism of association and interaction. The proposed statistical model implemented in a context of a novel design based on multiple GWAS data sets is a paradigm shifting-tool with applications to multiple industries.Funded Activity Details
Start Date: 06-2019
End Date: 06-2024
Funding Scheme: Discovery Projects
Funding Amount: $404,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Animal Breeding | Genomics | Genetics | Quantitative Genetics (incl. Disease and Trait Mapping Genetics)
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Agricultural and Veterinary Sciences | Expanding Knowledge in the Biological Sciences | Application Software Packages (excl. Computer Games) |
