Bridget Vermeulen

Growth differentiating factor-15 and its association with traditional cardiovascular risk factors: The African-PREDICT study

Publisher: Elsevier BV

Date: 06-2020

DOI: 10.1016/J.NUMECD.2020.03.001

Correction to: Growth differentiating factor-15 and adiposity in young adults: The African-PREDICT study

Publisher: Springer Science and Business Media LLC

Date: 10-05-2022

DOI: 10.1038/S41366-022-01145-9

Growth differentiating factor-15 and adiposity in young adults: The African-PREDICT study

Publisher: Springer Science and Business Media LLC

Date: 22-03-2021

DOI: 10.1038/S41366-021-00803-8

Abstract: Circulating growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine that increases in older in iduals with established cardiovascular disease (CVD) and obesity. To address potential targets in primary prevention, we aimed to determine whether body weight, waist circumference, waist/height ratio, body mass index (BMI), body surface area (BSA) and leptin associate with GDF-15 in young underweight, lean and overweight/obese (ow/ob) adults. We included 1189 adults aged 20-30 years. We grouped participants as underweight (BMI ≤ 18 kg/m Our findings may suggest that in young adults with either underweight or excess adiposity, increased GDF-15 levels may contribute to the development of future cardiovascular health risks associated with pro-inflammation.

North-West University

Location: South Africa

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University Of South Africa

Location: South Africa

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University Of The Witwatersrand

Location: South Africa

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North-West University , South Africa

Location: South Africa

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