ORCID Profile
0000-0001-8648-8032
Current Organisations
Universidad Científica del Sur
,
London School of Hygiene and Tropical Medicine
,
Universidad Peruana de Ciencias Aplicadas
,
Universidad Ricardo Palma
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Publications
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
Publisher: Elsevier BV
Date: 07-2010
Réplica: Las pruebas de laboratorio para la identificación de SARS-CoV-2 en tiempos de pandemia en el Perú: Algunas precisiones acerca del «rendimiento diagnóstico»
Publisher: Instituto Nacional de Salud (Peru)
Date: 24-09-2020
DOI: 10.17843/RPMESP.2020.373.5929
Abstract: -
Evaluation of a rapid serological test for detection of IgM and igG antibodies against SARS-CoV-2 under field conditions.
Publisher: Instituto Nacional de Salud (Peru)
Date: 21-04-2020
DOI: 10.17843/RPMESP.2020.372.5534
Abstract: To determine the additional diagnostic performance of a rapid serological test for detection of IgM and IgG antibodies compared to the real-time polymerase chain reaction (RT-PCR) test for detection of SARS-CoV-2. A cross-sectional study was carried out including patients hospitalized for COVID-19 in 3 hospitals, health workers exposed to the infection and outpatients who met suspicious case criteria, all of which underwent the molecular test (RT-PCR) and the rapid serological test. The additional diagnostic performance of rapid serological test was evaluated in comparison to molecular tests. Likewise, an approximation was made to the sensitivity and specificity of the rapid serological test. 144 people were included. With the rapid test, 19.4% of positive results were obtained compared to 11.1% in the molecular test (p = 0.03). The rapid serological test detected 21 cases that had been negative by the initial (RT-PCR), providing an additional diagnostic performance of 56.8% compared to the RT-PCR. The additional diagnostic performance was 50.0% during the first week, 70.0% during the second week and 50.0% during the third week of symptom onset. The sensitivity of the rapid serological test was 43.8% and the specificity of 98.9%. The rapid serological test was able to detect a greater number of cases than those detected by the molecular test especially after the second week of onset of symptoms. It also showed high specificity. It is therefore useful as a complementary test to RT-PCR, especially during the second and third week of illness.
Related Organisations
Limburgs Universitair Centrum (University Of Hasselt)
Location: Belgium
London School Of Hygiene And Tropical Medicine
Location: United Kingdom of Great Britain and Northern Ireland
Related Funding Activities
No related grants have been discovered for Alonso Soto.