ORCID Profile
0000-0003-3176-0689
Current Organisations
Helmholtz Centre Potsdam - GFZ German Research Centre for Geosciences
,
University of Pittsburgh
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Wiley
Date: 04-05-2023
DOI: 10.1002/ESSOAR.10512815.3
Abstract: Slow, aseismic slip plays a crucial role in the initiation, propagation and arrest of large earthquakes along active faults. In addition, aseismic slip controls the budget of elastic strain in the crust, hence the amount of energy available for upcoming earthquakes. The conditions for slow slip include specific material properties of the fault zone, pore fluid pressure and geometrical complexities of the fault plane. Fine scale descriptions of aseismic slip at the surface and at depth are key to determine the factors controlling the occurrence of slow, aseismic versus rapid, seismic fault slip. We focus on the spatial and temporal distribution of aseismic slip along the North Anatolian Fault, the plate boundary accommodating the 2 cm/yr of relative motion between Anatolia and Eurasia. Along the eastern termination of the rupture trace of the 1944 M7.3 Bolu-Gerede earthquake lies a segment that slips aseismically since at least the 1950’s. We use Sentinel 1 time series of displacement and GNSS data to provide a spatio-temporal description of the kinematics of fault slip. We show that aseismic slip observed at the surface is coincident with a shallow locking depth and that slow slip events with a return period of 2.5 years are restricted to a specific section of the fault. In the light of historical measurements, we discuss potential rheological implications of our results and propose a simple alternative model to explain the local occurrence of shallow aseismic slip at this location.
Publisher: eLife Sciences Publications, Ltd
Date: 20-04-2021
DOI: 10.7554/ELIFE.61138
Abstract: Aging is accompanied by disrupted information flow, resulting from accumulation of molecular mistakes. These mistakes ultimately give rise to debilitating disorders including skeletal muscle wasting, or sarcopenia. To derive a global metric of growing ‘disorderliness’ of aging muscle, we employed a statistical physics approach to estimate the state parameter, entropy, as a function of genes associated with hallmarks of aging. Escalating network entropy reached an inflection point at old age, while structural and functional alterations progressed into oldest-old age. To probe the potential for restoration of molecular ‘order’ and reversal of the sarcopenic phenotype, we systemically overexpressed the longevity protein, Klotho, via AAV. Klotho overexpression modulated genes representing all hallmarks of aging in old and oldest-old mice, but pathway enrichment revealed directions of changes were, for many genes, age-dependent. Functional improvements were also age-dependent. Klotho improved strength in old mice, but failed to induce benefits beyond the entropic tipping point.
Publisher: Wiley
Date: 16-11-2022
Publisher: American Geophysical Union (AGU)
Date: 07-2023
DOI: 10.1029/2022JB026018
Abstract: Slow, aseismic slip plays a crucial role in the initiation, propagation, and arrest of large earthquakes along active faults. In addition, aseismic slip controls the budget of elastic strain in the crust, hence the amount of energy available for upcoming earthquakes. The conditions for slow slip include specific material properties of the fault zone, pore fluid pressure, and geometrical complexities of the fault plane. Fine scale descriptions of aseismic slip at the surface and at depth are key to determine the factors controlling the occurrence of slow, aseismic versus rapid, seismic fault slip. We focus on the spatial and temporal distribution of aseismic slip along the North Anatolian Fault, the plate boundary accommodating the 2 cm/yr of relative motion between Anatolia and Eurasia. Along the eastern termination of the rupture trace of the 1944 M7.3 Bolu‐Gerede earthquake lies a segment that slips aseismically since at least the 1950s. We use Sentinel 1 time series of displacement and GNSS data to provide a spatio‐temporal description of the kinematics of fault slip. We show that aseismic slip observed at the surface is coincident with a shallow locking depth and that slow slip events with a return period of 2.5 years are restricted to a specific section of the fault. In the light of historical measurements, we discuss potential rheological implications of our results and propose a simple alternative model to explain the local occurrence of shallow aseismic slip at this location.
Publisher: Cold Spring Harbor Laboratory
Date: 24-07-2020
DOI: 10.1101/2020.07.22.207043
Abstract: Aging is accompanied by a disrupted information flow, which results from accumulation of molecular mistakes. These mistakes ultimately give rise to debilitating disorders such as skeletal muscle wasting, or sarcopenia. To estimate the growing “disorderliness” of the aging muscle system, we employed a statistical physics approach to estimate the state parameter, entropy, as a function of genes associated with hallmarks of aging. Although the most prominent structural and functional alterations were observed in the oldest old mice (27-29 months), we found that the escalating network entropy reached an inflection point at old age (22-24 months). To probe the potential for restoration of molecular “order” and reversal of the sarcopenic phenotype, we overexpressed the longevity protein, α-Klotho. Klotho overexpression modulated genes representing all hallmarks of aging in both old and oldest-old mice. However, whereas Klotho improved strength in old mice, intervention failed to induce a benefit beyond the entropic tipping point.
Location: Germany
Location: India
Location: United States of America
No related grants have been discovered for Jorge Jara.