ORCID Profile
0000-0003-2492-653X
Current Organisations
Virginia Tech Carilion Research Institute
,
Baylor College of Medicine
,
Nanyang Technological University
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Publications
Neural Correlates of Value, Risk, and Risk Aversion Contributing to Decision Making under Risk
Publisher: Society for Neuroscience
Date: 07-10-2009
DOI: 10.1523/JNEUROSCI.2614-09.2009
Abstract: Decision making under risk is central to human behavior. Economic decision theory suggests that value, risk, and risk aversion influence choice behavior. Although previous studies identified neural correlates of decision parameters, the contribution of these correlates to actual choices is unknown. In two different experiments, participants chose between risky and safe options. We identified discrete blood oxygen level-dependent (BOLD) correlates of value and risk in the ventral striatum and anterior cingulate, respectively. Notably, increasing inferior frontal gyrus activity to low risk and safe options correlated with higher risk aversion. Importantly, the combination of these BOLD responses effectively decoded the behavioral choice. Striatal value and cingulate risk responses increased the probability of a risky choice, whereas inferior frontal gyrus responses showed the inverse relationship. These findings suggest that the BOLD correlates of decision factors are appropriate for an ideal observer to detect behavioral choices. More generally, these biological data contribute to the validity of the theoretical decision parameters for actual decisions under risk.
Health Effects of Underground Workspaces cohort: study design and baseline characteristics
Publisher: Korean Society of Epidemiology
Date: 16-08-2019
Abstract: The development of underground workspaces is a strategic effort towards healthy urban growth in cities with ever-increasing land scarcity. Despite the growth in underground workspaces, there is limited information regarding the impact of this environment on workers’ health. The Health Effects of Underground Workspaces (HEUW) study is a cohort study that was set up to examine the health effects of working in underground workspaces. In this paper, we describe the rationale for the study, study design, data collection, and baseline characteristics of participants. The HEUW study recruited 464 participants at baseline, of whom 424 (91.4%) were followed-up at 3 months and 334 (72.0%) at 12 months from baseline. We used standardized and validated questionnaires to collect information on socio-demographic and lifestyle characteristics, medical history, family history of chronic diseases, sleep quality, health-related quality of life, chronotype, psychological distress, occupational factors, and comfort levels with indoor environmental quality parameters. Clinical and anthropometric parameters including blood pressure, spirometry, height, weight, and waist and hip circumference were also measured. Biochemical tests of participants’ blood and urine s les were conducted to measure levels of glucose, lipids, and melatonin. We also conducted objective measurements of in iduals’ workplace environment, assessing air quality, light intensity, temperature, thermal comfort, and bacterial and fungal counts. The findings this study will help to identify modifiable lifestyle and environmental parameters that are negatively affecting workers’ health. The findings may be used to guide the development of more health-promoting workspaces that attempt to negate any potential deleterious health effects from working in underground workspaces.
Underground Workspaces: A Human Factors Approach
Publisher: Springer International Publishing
Date: 08-08-2018
Prevalence of and factors associated with poor sleep quality and short sleep in a working population in Singapore
Publisher: Elsevier BV
Date: 06-2020
DOI: 10.1016/J.SLEH.2019.10.008
Abstract: We aimed to examine the prevalence of poor sleep quality and short sleep and their associated factors in a working population in Singapore. This is a cross-sectional analysis. Four companies in Singapore were included in this study. Participants included 464 full-time employees (aged ≥21 years). Self-reported sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Self-administered questionnaires were used to collect data on sociodemographic characteristics, health behaviours, medical history, chronotype, psychosocial factors, health-related quality of life (HRQoL) and occupational factors. Clinical measurements were performed using standard tools and protocols. Multivariate logistic regression was used to examine the factors associated with poor sleep quality (PSQI global score >5) and short sleep (<7 hours/night). The mean age was 39.0 (SD: 11.4) years, and 79.5% were men. The prevalence of poor sleep quality was 42.5%, and 66.2% were short sleepers. Nearly three-fourths (71.3%) had at least one of these two conditions. Age, Malay ethnicity (vs. Chinese), chronic conditions, poorer mental health, stress at home or work and shift work were positively associated, and mental component summary of the HRQoL scale and work years in the current company were negatively associated with poor sleep quality. Age, Malay and Indian ethnicities (vs. Chinese), longer dinner-to-bed time, snacking between dinner and bed time, and poorer mental health were positively associated with short sleep. Poor sleep quality and short sleep were highly common in this working population in Singapore. Workplace policies should include education and intervention programmes to promote better sleep hygiene.
Related Organisations
University Of Cambridge
Location: United Kingdom of Great Britain and Northern Ireland
Virginia Tech Carilion Research Institute
Location: United States of America
Related Funding Activities
No related grants have been discovered for George Christopoulos.