ORCID Profile
0000-0002-8945-5153
Current Organisations
Victoria University of Wellington
,
Naturhistorisches Museum Wien
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Publisher: Cold Spring Harbor Laboratory
Date: 04-08-2018
DOI: 10.1101/382945
Abstract: Arthropods comprise the largest and most erse phylum on Earth and play vital roles in nearly every ecosystem. Their ersity stems in part from variations on a conserved body plan, resulting from and recorded in adaptive changes in the genome. Dissection of the genomic record of sequence change enables broad questions regarding genome evolution to be addressed, even across hyper- erse taxa within arthropods. Using 76 whole genome sequences representing 21 orders spanning more than 500 million years of arthropod evolution, we document changes in gene and protein domain content and provide temporal and phylogenetic context for interpreting these innovations. We identify many novel gene families that arose early in the evolution of arthropods and during the ersification of insects into modern orders. We reveal unexpected variation in patterns of DNA methylation across arthropods and ex les of gene family and protein domain evolution coincident with the appearance of notable phenotypic and physiological adaptations such as flight, metamorphosis, sociality and chemoperception. These analyses demonstrate how large-scale comparative genomics can provide broad new insights into the genotype to phenotype map and generate testable hypotheses about the evolution of animal ersity.
Publisher: Springer Science and Business Media LLC
Date: 23-01-2020
DOI: 10.1186/S13059-019-1925-7
Abstract: Arthropods comprise the largest and most erse phylum on Earth and play vital roles in nearly every ecosystem. Their ersity stems in part from variations on a conserved body plan, resulting from and recorded in adaptive changes in the genome. Dissection of the genomic record of sequence change enables broad questions regarding genome evolution to be addressed, even across hyper- erse taxa within arthropods. Using 76 whole genome sequences representing 21 orders spanning more than 500 million years of arthropod evolution, we document changes in gene and protein domain content and provide temporal and phylogenetic context for interpreting these innovations. We identify many novel gene families that arose early in the evolution of arthropods and during the ersification of insects into modern orders. We reveal unexpected variation in patterns of DNA methylation across arthropods and ex les of gene family and protein domain evolution coincident with the appearance of notable phenotypic and physiological adaptations such as flight, metamorphosis, sociality, and chemoperception. These analyses demonstrate how large-scale comparative genomics can provide broad new insights into the genotype to phenotype map and generate testable hypotheses about the evolution of animal ersity.
Publisher: American Association for the Advancement of Science (AAAS)
Date: 07-11-2014
Abstract: Insects are the most erse group of animals, with the largest number of species. However, many of the evolutionary relationships between insect species have been controversial and difficult to resolve. Misof et al. performed a phylogenomic analysis of protein-coding genes from all major insect orders and close relatives, resolving the placement of taxa. The authors used this resolved phylogenetic tree together with fossil analysis to date the origin of insects to ~479 million years ago and to resolve long-controversial subjects in insect phylogeny. Science , this issue p. 763
Publisher: Oxford University Press (OUP)
Date: 18-10-2013
Publisher: IOP Publishing
Date: 07-09-2023
Abstract: Superconducting electric motors offer the potential for low weight and high power in applications such as electric aircraft and high speed marine transport. Combined with renewably-sourced cryogenic fuels and advanced fuel cells they offer a path to zero-carbon mass transport. The proposed architectures of these extreme machines, operating at temperatures around 20K to 50K and employing very high alternating magnetic fields, require materials for the stator that are not electrically conducting and at the same time have good cryogenic structural performance. & #xD Additively manufactured (AM) materials can play a key role in these designs, and a collaboration between the Robinson Research Institute and AUT is studying the performance of a range of composite polymers in superconducting machine applications. There are significant challenges to be met, including understanding the effect of the build process on material properties at low temperatures, and also the effect of formulation changes on thermal properties.& #xD Additively manufactured metals can be employed in the rotor components, where the magnetic field fluctuations are very small for our synchronous designs. In this usage case, we can achieve dramatic reductions in the weight of the rotor assembly by minimising the number of joints and facilitating the design of multi-functional components in our helium cooled, vacuum cryostat architecture.& #xD Novel design solutions have been developed for several key components in our prototype machines and these are discussed, along with cryogenic testing results for selected additively manufactured polymers and composites. & #xD
No related grants have been discovered for Nikolaus Szucsich.