ORCID Profile
0000-0002-7635-6885
Current Organisation
OZM Research (Czechia)
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Publisher: IOP Publishing
Date: 10-2016
Publisher: Elsevier BV
Date: 08-2013
Publisher: Elsevier BV
Date: 09-2014
Publisher: Elsevier BV
Date: 12-2015
Publisher: Wiley
Date: 26-05-2014
Abstract: A new method for the characterisation of purified detonation nanodiamond (DND) using CZE has been developed. The influence of BGE conditions on electrophoretic mobility, peak shape and particle aggregation was investigated, with resultant observations supported by zeta potential approximations and particle size measurements. Sodium tetraborate (pH 9.3), Tris (pH 9.3) and sodium phosphate (pH 7) were used in studying the BGE concentration effect on a commercial source of chemically stabilised DND. The BGE concentration had a strong effect on the stability of DND in suspension. The formation of aggregates of various sizes was observed as BGE concentration increased. The effect of pH on the electromigration of DND was examined using sodium phosphate (pH 8 and 10). The CZE method was subsequently applied to four different DND s les, which had undergone different routes of purification following detonation synthesis. Each s le produced a unique electrophoretic peak or profile in sodium tetraborate buffer (pH 9.3), such that the actual separation of DND s les from different sources could be achieved.
Publisher: Elsevier BV
Date: 2017
Publisher: Frontiers Media SA
Date: 30-06-2021
DOI: 10.3389/FBIOE.2021.637587
Abstract: The potential biomedical applications of nanodiamond have been considered over the last few decades. However, there is still uncertainty regarding the extent to which the surface characteristics of this material can influence potential applications. The present study investigated the effects of surface characteristics alongside the prospective of improving nanodiamond production using cold plasma and microwave technologies for the surface tailoring of the nanocarbons. Numerous approaches were applied to purify, refine and modify a group of nanosized diamonds at each step of their production cycle: from the detonation soot as the initial raw material to already certified s les. The degree of surface changes were deliberately performed slowly and kept at different non-diamond carbon presence stages, non-carbon elemental content, and amount converted superficial moieties. In total, 21 treatment procedures and 35 types of nanosize diamond products were investigated. In addition cultures of human fibroblast cells showed enhanced viability in the presence of many of the processed nanodiamonds, indicating the potential for dermal applications of these remarkable nanomaterials.
Publisher: Elsevier BV
Date: 02-2018
Publisher: Elsevier BV
Date: 02-2018
Publisher: IOP Publishing
Date: 09-02-2016
Publisher: Springer Science and Business Media LLC
Date: 24-07-2017
DOI: 10.1007/S00709-017-1146-4
Abstract: Detonation nanodiamonds (DNDs) are carbon-based nanomaterials that are among the most promising nanoparticles available for biomedical applications so far. This is due to their biocompatibility, which could be contributed to their inert core and conformable surface nature. However, DNDs cytotoxicity for urothelial cells and the routes of their internalization remains an open question in the aspect of nanodiamond surface. We therefore analyzed four types of DNDs for cytotoxicity and internalization with normal urothelial cells and two types of cancer urothelial cell lines in vitro. Viability of any of the cell types we used was not compromised with any of four DNDs we evaluated after 24-, 48- and 72-h incubation in three different concentrations of DNDs. Transmission electron microscopy revealed that all four types of DNDs were endocytosed into all three types of urothelial cells tested here. We observed DNDs in endosomes, as well as in multivesicular bodies and multilamellar bodies. These results propose using of DNDs as a delivery system for urological applications in human nanomedicine.
Publisher: Elsevier BV
Date: 10-2007
Publisher: Springer Science and Business Media LLC
Date: 30-01-2014
Publisher: Elsevier BV
Date: 08-2006
DOI: 10.1016/J.JCIS.2006.03.028
Abstract: Iron oxide modified diamond blends containing different amounts of ultradispersed diamond were prepared and characterized by nitrogen physisorption, X-ray diffraction, temperature programmed reduction, Mössbauer and IR spectroscopy. The catalytic behavior of these composite materials in methanol decomposition to hydrogen, carbon monoxide, and methane has been also studied. The initial state and phase transformations of the supported highly dispersed iron oxide particles in various pretreatment media, as well as their reductive and catalytic properties, strongly depend on the ultradispersed diamond content in the diamond blends.
Publisher: Elsevier
Date: 2017
Publisher: IOP Publishing
Date: 2017
Location: Bulgaria
Location: Australia
Location: Bulgaria
Location: Bulgaria
Location: Bulgaria
Start Date: 2013
End Date: 2017
Funder: European Commission
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