ORCID Profile
0000-0002-1140-0718
Current Organisations
Instituto Gulbenkian de Ciencia
,
Centre National de la Recherche Scientifique
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Publisher: Cold Spring Harbor Laboratory
Date: 24-08-2023
DOI: 10.1101/2023.08.23.553838
Abstract: Several African mammals exhibit a phylogeographic pattern where closely related taxa are split between West/Central and East/Southern Africa, but their evolutionary relationships and histories remain controversial. Bushpigs ( Potamochoerus larvatus ) and red river hogs ( P. porcus ) are recognised as separate species due to morphological distinctions, a perceived lack of interbreeding at contact, and putatively old ergence times, but historically, they were considered conspecific. Moreover, the presence of Malagasy bushpigs as the sole large terrestrial mammal shared with the African mainland raises intriguing questions about its origin and arrival in Madagascar. Analyses of 67 whole genomes revealed a genetic continuum between the two species, with putative signatures of historical gene flow, variable F ST values, and a recent ergence time ( ,000 years). Thus, our study challenges key arguments for splitting Potamochoerus into two species and suggests their speciation might be incomplete. Our findings also indicate that Malagasy bushpigs erged from southern African populations and underwent a limited bottleneck 1,000-5,000 years ago, concurrent with human arrival in Madagascar. These results shed new light on the evolutionary history of an iconic and widespread African genus and provide insight into the longstanding biogeographic puzzle surrounding the bushpig’s presence in Madagascar.
Publisher: Wiley
Date: 28-01-2013
DOI: 10.1002/AJPA.22222
Abstract: Many lemur species are arboreal, elusive, and/or nocturnal and are consequently difficult to approach, observe and catch. In addition, most of them are endangered. For these reasons, non-invasive s ling is especially useful in primates including lemurs. A key issue in conservation and ecological studies is to identify the sex of the s led in iduals to investigate sex-biased dispersal, parentage, social organization and population sex ratio. Several molecular tests of sex are available in apes and monkeys, but only a handful of them work in the lemuriform clade. Among these tests, the co lification of the SRY gene with the amelogenin X gene using strepsirhine-specific X primers seems particularly promising, but the reliability and validity of this sexing test have not been properly assessed yet. In this study, we (i) show that this molecular sexing test works on three additional lemur species (Microcebus tavaratra, Propithecus coronatus and P. verreauxi) from two previously untested genera and one previously untested family, suggesting that these markers are likely to be universal among lemurs and other strepsirrhines (ii) provide the first evidence that this PCR-based sexing test works on degraded DNA obtained from noninvasive s les (iii) validate the approach using a large number of known-sex in iduals and a multiple-tubes approach, and show that mismatches between the field sex and the final molecular consensus sex occur in less than 10% of all the s les and that most of these mismatches were likely linked to incorrect sex determinations in the field rather than genotyping errors.
Publisher: Elsevier BV
Date: 02-1998
DOI: 10.1086/301719
Publisher: Springer Science and Business Media LLC
Date: 2014
Publisher: Wiley
Date: 02-2010
Publisher: Public Library of Science (PLoS)
Date: 15-11-2012
Publisher: Elsevier BV
Date: 06-2000
DOI: 10.1016/S1383-5742(00)00004-1
Abstract: The conservation of genetic ersity has emerged as one of the central issues in conservation biology. Although researchers in the areas of evolutionary biology, population management, and conservation biology routinely investigate genetic variability in natural populations, only a handful of studies have addressed the effects of chemical contamination on population genetics. Chemical contamination can cause population reduction by the effects of somatic and heritable mutations, as well as non-genetic modes of toxicity. Stochastic processes in small populations, increased mutation load, and the phenomenon of mutational meltdown are compounding factors that cause reduced fitness and accelerate the process of population extirpation. Although the original damage caused by chemical contaminants is at the molecular level, there are emergent effects at the level of populations, such as the loss of genetic ersity, that are not predictable based solely on knowledge of the mechanism of toxicity of the chemical contaminants. Therefore, the study of evolutionary toxicology, which encompasses the population-genetic effects of environmental contaminants, should be an important focus of ecotoxicology. This paper reviews the issues surrounding the genetic effects of pollution, summarizes the technical approaches that can be used to address these issues, and provides ex les of studies that have addressed some of them.
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: France
No related grants have been discovered for Lounes Chikhi.