ORCID Profile
0000-0002-0254-025X
Current Organisation
University of Leeds
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0GC01247E
Abstract: This tutorial bridges an important knowledge gap by providing an easily accessible introduction that enables synthetic chemists to explore synthetic electrochemistry.
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2CY00587E
Abstract: An integrated flow platform enables the electrochemical synthesis of base-metal catalysts with high-throughput screening and rapid data generation.
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D0RE00399A
Abstract: Improved synthesis through the use of alternating polarity.
Publisher: International Union of Crystallography (IUCr)
Date: 31-10-2014
DOI: 10.1107/S1600536814023423
Abstract: The title compound [Na 3 (C 11 H 6 NO 3 ) 2 (C 2 H 3 O 2 )] n , crystallized through diffusion of diethyl ether into methanol as needles. There are three crystallographically independent Na + cations present, each exhibiting a distorted octahedral coordination geometry, two through coordination by five O atoms and one N atom, and one through coordination by six O atoms. A series of intermolecular O...Na and N...Na contacts leads to the formation of chains along the a- axis direction.
Publisher: Wiley
Date: 15-04-2016
Publisher: Royal Society of Chemistry (RSC)
Date: 2012
DOI: 10.1039/C1CY00241D
Publisher: Georg Thieme Verlag KG
Date: 07-11-2017
Abstract: The direct glycosylation of ceramides in supercritical carbon dioxide (scCO2) successfully proceeded to produce β-glycolipids in high yield and with full stereoselectivity. The reaction is promoted by montmorillonite modified with a superacid (CF3SO3H). The value of this protocol was demonstrated in the efficient synthesis of isoglobotrihexosylceramide (iGB3).
Publisher: Springer Science and Business Media LLC
Date: 13-11-2020
DOI: 10.1038/S41467-020-19594-Z
Abstract: Solubility prediction remains a critical challenge in drug development, synthetic route and chemical process design, extraction and crystallisation. Here we report a successful approach to solubility prediction in organic solvents and water using a combination of machine learning (ANN, SVM, RF, ExtraTrees, Bagging and GP) and computational chemistry. Rational interpretation of dissolution process into a numerical problem led to a small set of selected descriptors and subsequent predictions which are independent of the applied machine learning method. These models gave significantly more accurate predictions compared to benchmarked open-access and commercial tools, achieving accuracy close to the expected level of noise in training data (LogS ± 0.7). Finally, they reproduced physicochemical relationship between solubility and molecular properties in different solvents, which led to rational approaches to improve the accuracy of each models.
Publisher: American Chemical Society (ACS)
Date: 23-04-2021
Publisher: Elsevier BV
Date: 12-2002
Publisher: Royal Society of Chemistry (RSC)
Date: 2012
DOI: 10.1039/C2OB07034K
Abstract: By using DABCO·(SO(2))(2), DABSO, as a solid bench-stable SO(2)-equivalent, the palladium-catalysed aminosulfonylation of aryl-, alkenyl- and heteroaryl halides has been achieved. N,N-Dialkylhydrazines are employed as the N-nucleophiles and provide N-aminosulfonamides as the products in good to excellent yields. The reactions are operationally simple to perform, requiring only a slight excess of SO(2) (1.2-2.2 equiv.), and tolerate a variety of substituents on the halide coupling partner. Variation of the hydrazine component is also demonstrated. The use of N,N-dibenzylhydrazine as the N-nucleophile delivers N-aminosulfonamide products that can be converted into the corresponding primary sulfonamides using a high-yielding, telescoped, deprotection sequence. The ability to employ hydrazine·SO(2) complexes as both the N-nucleophile and SO(2) source is also illustrated.
Publisher: American Chemical Society (ACS)
Date: 30-05-2023
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0DT01694B
Abstract: Ligand space for bidentates has been mapped, computationally, varying donors, substituents and backbones, to give a new database, LKB-bid.
Publisher: American Chemical Society (ACS)
Date: 20-07-2017
Publisher: Royal Society of Chemistry (RSC)
Date: 2008
DOI: 10.1039/B807669C
Abstract: In situ resolution of the rapidly racemising diphosphine BIPHEP and its relatives with the cationic Rh complex of (S,S)-bicyclonona-2,6-diene permits the asymmetric hydrogenation of dehydroamino esters.
Publisher: Royal Society of Chemistry (RSC)
Date: 2016
DOI: 10.1039/C6GC01601D
Abstract: A route to access the privileged imidazo[1,2- a ]pyridine scaffold in one step, 1–10 minutes using only aqueous NaOH, is reported.
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C4CC08874C
Abstract: An electrochemical flow-cell has been developed for the highly efficient and selective generation of organometallic Cu I –N-heterocyclic carbene complexes under neutral and ambient conditions.
Publisher: American Chemical Society (ACS)
Date: 28-10-2010
DOI: 10.1021/JA1081124
Abstract: The palladium-catalyzed three-component coupling of aryl iodides, sulfur dioxide, and hydrazines to deliver aryl N-aminosulfonamides is described. The colorless crystalline solid DABCO·(SO(2))(2) was used as a convenient source of sulfur dioxide. The reaction tolerates significant variation of both the aryl iodide and hydrazine coupling partners.
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C5DT02194D
Abstract: Electronically erse pyridyl-substituted Pd( ii )-NHC complexes have been employed in Suzuki–Miyaura cross-coupling to yield a sterically congested tetra- ortho -substituted biaryl product.
Publisher: Royal Society of Chemistry (RSC)
Date: 2014
DOI: 10.1039/C4CY00480A
Abstract: The first observation of guanidine–CO 2 ‘activation’ complexes in solution and their implications on the catalytic activity of guanidines are reported.
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7SC02859H
Abstract: A mechanistic investigation of Ullmann–Goldberg reactions using common bases led to the identification of pathways for catalyst deactivation. The solid form of the inorganic phase was found to have critical influence on the mechanism of the reaction.
Publisher: Wiley
Date: 28-09-2007
Publisher: Royal Society of Chemistry (RSC)
Date: 2023
DOI: 10.1039/D3CY00083D
Abstract: A novel semi-automated, high-throughput computational workflow for ligand/catalyst discovery based on the Cambridge Structural Database is reported.
Publisher: American Chemical Society (ACS)
Date: 22-09-2021
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1RE00205H
Abstract: An automated separation system is described for identifying the optimal conditions for purifying an amine from a mixture.
Publisher: International Union of Crystallography (IUCr)
Date: 10-2015
DOI: 10.1107/S1600577515016148
Abstract: The 2–4 keV energy range provides a rich window into many facets of materials science and chemistry. Within this window, P, S, Cl, K and Ca K -edges may be found along with the L -edges of industrially important elements from Y through to Sn. Yet, compared with those that cater for energies above ca. 4–5 keV, there are relatively few resources available for X-ray spectroscopy below these energies. In addition, in situ or operando studies become to varying degrees more challenging than at higher X-ray energies due to restrictions imposed by the lower energies of the X-rays upon the design and construction of appropriate s le environments. The XMaS beamline at the ESRF has recently made efforts to extend its operational energy range to include this softer end of the X-ray spectrum. In this report the resulting performance of this resource for X-ray spectroscopy is detailed with specific attention drawn to: understanding electrostatic and charge transfer effects at the S K -edge in ionic liquids quantification of dilution limits at the Cl K - and Rh L 3 -edges and structural equilibria in solution in vacuum deposition and reduction of [Rh I (CO) 2 Cl] 2 to γ-Al 2 O 3 contamination of γ-Al 2 O 3 by Cl and its potential role in determining the chemical character of supported Rh catalysts and the development of chlorinated Pd catalysts in `green' solvent systems. S le environments thus far developed are also presented, characterized and their overall performance evaluated.
Publisher: American Chemical Society (ACS)
Date: 12-03-2012
DOI: 10.1021/OM300030E
Publisher: Wiley
Date: 06-2009
Publisher: Elsevier BV
Date: 06-2014
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C5DT02104A
Abstract: Electronic structures of Pd( ii ), Pd( iii ) and Pd( iv ) complexes were examined using X-ray crystallography and absorption spectroscopy, supplemented by theoretical calculations.
Publisher: Informa UK Limited
Date: 21-02-2017
Publisher: American Chemical Society (ACS)
Date: 23-03-2018
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Start Date: 2018
End Date: 2022
Funder: Engineering and Physical Sciences Research Council
View Funded ActivityStart Date: 2019
End Date: 2022
Funder: Engineering and Physical Sciences Research Council
View Funded ActivityStart Date: 2016
End Date: 2016
Funder: Royal Society of Chemistry
View Funded ActivityStart Date: 2017
End Date: 2017
Funder: British Council
View Funded ActivityStart Date: 2011
End Date: 2012
Funder: Royal Society
View Funded Activity