ORCID Profile
0000-0001-9595-9879
Current Organisations
University of Cape Coast
,
Goethe-University Frankfurt, Unviversity Hospital
,
International Water Management Institute
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Publisher: Springer Science and Business Media LLC
Date: 05-02-2016
Publisher: Informa UK Limited
Date: 09-02-2022
Publisher: Palacky University Olomouc
Date: 14-05-2020
Publisher: Springer International Publishing
Date: 2021
Publisher: Informa UK Limited
Date: 31-01-2019
Publisher: Elsevier BV
Date: 04-2022
Publisher: MDPI AG
Date: 09-05-2022
DOI: 10.3390/SU14095715
Abstract: This paper discusses how climatic and non-climatic factors, either separately or together, shape the adaptation responses of smallholder farmers in the Raya Azebo district of Ethiopia. Their adaptation responses included adjusting planting periods, crop ersification, changing crop types, adopting improved seeds, using irrigation, conducting migration, participation in wage employment, selling local food and drinks, and owning small shops. These adaptation responses were motivated by various climatic (e.g., drought and rainfall variability) as well as non-climatic factors (e.g., market conditions, yield-related factors, land scarcity, labor shortages, soil fertility issues, crop diseases, and limited local employment options). We therefore argue (i) that successful adaptation requires a broader understanding not just of climatic factors but also of the various social-ecological factors that shape smallholder farmers’ adaptations and (ii) that the successful design and implementation of locally appropriate planned adaptation interventions require the inclusion of both climatic and non-climatic factors.
Publisher: Springer International Publishing
Date: 2021
Publisher: Elsevier BV
Date: 04-2019
Publisher: MDPI AG
Date: 05-07-2022
Abstract: Chronic obstructive pulmonary disease (COPD) is a disease with an inflammatory phenotype with increasing prevalence in the elderly. Expanded population of mutant blood cells carrying somatic mutations is termed clonal hematopoiesis of indeterminate potential (CHIP). The association between CHIP and COPD and its relevant effects on DNA methylation in aging are mainly unknown. Analyzing the deep-targeted licon sequencing from 125 COPD patients, we found enhanced incidence of CHIP mutations (~20%) with a predominance of DNMT3A CHIP-mediated hypomethylation of Phospholipase D Family Member 5 (PLD5), which in turn is positively correlated with increased levels of glycerol phosphocholine, pro-inflammatory cytokines, and deteriorating lung function.
No related grants have been discovered for Gerald Atampugre.