ORCID Profile
0000-0001-7519-977X
Current Organisation
The University of Texas at Dallas
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In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Macromolecular materials | Macromolecular and Materials Chemistry | Nanochemistry and Supramolecular Chemistry | Nanotechnology | Materials engineering | Biochemistry and cell biology | Synthesis Of Macromolecules | Nanotechnology | Organic Chemistry | Catalysis and Mechanisms of Reactions | Synthetic biology | Synthesis of Materials | Colloid And Surface Chemistry | Physical Organic Chemistry | Nanomanufacturing | Polymers and plastics | Macromolecular and materials chemistry | Functional materials | Nanomanufacturing | Nanomaterials | Microtechnology | Microbial genetics |
Expanding Knowledge in the Chemical Sciences | Diagnostic methods | Chemical sciences | Physical sciences | Expanding Knowledge in the Medical and Health Sciences | Industrial Chemicals and Related Products not elsewhere classified | Expanding Knowledge in the Physical Sciences | Expanding Knowledge in Engineering |
Publisher: Wiley
Date: 27-07-2017
Abstract: Hydrogen sulfide (H
Publisher: Wiley
Date: 10-08-2016
DOI: 10.1002/POLA.28242
Publisher: Wiley
Date: 13-03-2020
Abstract: The most pressing challenges for light‐driven hydrogel actuators include reliance on UV light, slow response, poor mechanical properties, and limited functionalities. Now, a supramolecular design strategy is used to address these issues. Key is the use of a benzylimine‐functionalized anthracene group, which red‐shifts the absorption into the visible region and also stabilizes the supramolecular network through π–π interactions. Acid–ether hydrogen bonds are incorporated for energy dissipation under mechanical deformation and maintaining hydrophilicity of the network. This double‐crosslinked supramolecular hydrogel developed via a simple synthesis exhibits a unique combination of high strength, rapid self‐healing, and fast visible‐light‐driven shape morphing both in the wet and dry state. As all of the interactions are dynamic, the design enables the structures to be recycled and reprogrammed into different 3D objects.
Publisher: American Chemical Society (ACS)
Date: 23-01-2009
DOI: 10.1021/CM803011W
Publisher: Elsevier BV
Date: 10-2009
DOI: 10.1016/J.BIOMATERIALS.2009.07.040
Abstract: Polymer capsules containing multiple liposomes, termed capsosomes, are a promising new concept toward the design of artificial cells. Herein, we report on the fundamental aspects underpinning the assembly of capsosomes. A stable and high loading of intact liposomal cargo into a polymer film was achieved by non-covalently sandwiching the liposomes between a tailor-made cholesterol-modified poly(L-lysine) (PLL(c)) precursor layer and a poly(methacrylic acid)-co-(cholesteryl methacrylate) (PMA(c)) capping layer. The film assembly, optimized on planar surfaces, was successfully transferred onto colloidal substrates, and a polymer membrane was subsequently assembled by the alternating adsorption of poly(N-vinyl pyrrolidone) (PVP) and thiol-modified poly(methacrylic acid) (PMA(SH)) onto the pre-adsorbed layer of liposomes. Upon removal of the silica template, stable capsosomes encapsulating the enzyme luciferase or beta-lactamase within their liposomal sub-compartments were obtained at both assembly (pH 4) and physiological conditions (pH 7.4). Excellent retention of the liposomes and the enzymatic cargo within the polymer carrier capsules was observed for up to 14 days. These engineered capsosomes are particularly attractive as autonomous microreactors, which can be utilized to repetitively add smaller reactants to cause successive distinct reactions within the capsosomes and simultaneously release the products to the surrounding environment, bringing these systems one step closer toward constructing artificial cells.
Publisher: American Chemical Society (ACS)
Date: 04-06-2010
DOI: 10.1021/LA100686M
Abstract: We demonstrate the synthesis and use of a spiropyran functional polymer to form highly ordered honeycomb materials by the breath figure technique, which is based on the self-assembly of water droplets. These materials undergo rapid and intense color changes both in solution and as porous films by irradiation with light (UV or visible). We also demonstrate the metal binding ability of these polymers ultimately to create hybrid organic-inorganic porous structures. Furthermore, by reduction of the metal and calcination of the organic materials, unique palladium microrings can be prepared. The methods described are general techniques that may be applied to a range of heavy metals.
Publisher: American Chemical Society (ACS)
Date: 03-2017
Publisher: Wiley
Date: 24-01-2017
Abstract: The dynamic covalent characteristics of oxime and boronate ester bonds have been explored. A small excess of a competing aldehyde under acidic conditions resulted in oxime polymer degradation from high molecular weights (30 kDa) to low molecular weight oligomers (2.2 kDa). The dynamic nature of oxime bonds imparts oxime cross-linked hydrogels with self-healing properties and the incorporation of phenyl boronic acid groups into the hydrogel network provides a platform for hydrogel functionalization. The addition of a polyphenol (tannic acid) proves a facile means to incorporate a second, dynamic covalent cross-linking network through boronate ester formation which, owing to the increase in the degree of cross-linking, is found to be nearly double the hydrogel strength (storage modulus increased from 4.6 to 8.5 kPa). Finally, the tannic acid cross-linking network is selectively degraded returning the hydrogel storage modulus to its initial value and providing a means for the synthesis of materials with tunable mechanical properties.
Publisher: American Chemical Society (ACS)
Date: 13-03-2008
DOI: 10.1021/MA7019557
Publisher: Royal Society of Chemistry (RSC)
Date: 2016
DOI: 10.1039/C5PY01915J
Abstract: Reductive amination facilitates the protecting group free post-polymerization functionalisation of a temperature responsive, aldehyde-containing polymer with histidine.
Publisher: Wiley
Date: 10-03-2023
DOI: 10.1002/POL.20230005
Abstract: Petroleum‐derived monomers are the most common building blocks for ester‐based thermosets. Bio‐derived thermoset elastomers are becoming viable alternatives to conventional thermosets. Herein, we developed a biobased vitrimer‐type thermoset elastomers using abundant and sustainable raspberry ketone as feedstock. We utilize raspberry ketone to create building blocks for dynamic oxime chemistry and crosslinked these through free radical polymerization with poly(ethylene glycol) methyl ether methacrylate as a comonomer. In contrast to other dynamic networks based on ester bonds, which need catalysts, this is undesirable since catalyst deactivation or leaching lowers its effect over time and may impair reuse. This network incorporates catalyst‐free bond exchange reactions in catalyst‐dependent polyester networks by substituting oxime‐esters for typical ester linkages. The elastomer exhibits stress relaxation, a low glass transition temperature (T g ) (−55 to −40.2°C) and tensile strength up to 5.2 ± 3.0 kPa. Furthermore, the dynamic oxime transesterification exchange mechanism allows elastomers to be reprocessed using a hot press at 160°C and 8 × 10 3 kPa pressure. After reprocessing, the tensile strength of elastomers can be recovered up to 78.1 ± 10.9%. This work integrates the principles of catalyst‐free dynamic exchange process and mechanical recycling coupled with biobased components to provide a rational solution towards conventional elastomers. In the future, these elastomers can be exploited for the development of hydrogels, recyclable elastomers, and commodity plastics.
Publisher: Wiley
Date: 24-08-2011
Publisher: Elsevier BV
Date: 03-2018
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C7PY01945A
Abstract: 3D-printable self-healing oxime gels have been reinforced by cryogelation, making these gels mechanically tuneable, macroporous, and doubly dynamic.
Publisher: Wiley
Date: 03-2018
Publisher: Wiley
Date: 12-04-2019
Abstract: Dynamic bonds have achieved significant attention for their ability to impart fascinating properties to polymeric materials, such as high mechanical strength, self-healing, shape memory, 3D printability, and conductivity. Incorporating multiple dynamic bonds into polymer systems affords an attractive and efficient approach to endow multiple functionalities. This mini-review focuses on the use of complementary dynamic interactions to control the properties of soft materials. Owing to the ersity in dynamic chemistries that can be explored, the scope of this article is restricted to polymers and does not include colloids, hiphiles, liquid crystals, or biological soft matter.
Publisher: Wiley
Date: 13-03-2020
Abstract: The most pressing challenges for light‐driven hydrogel actuators include reliance on UV light, slow response, poor mechanical properties, and limited functionalities. Now, a supramolecular design strategy is used to address these issues. Key is the use of a benzylimine‐functionalized anthracene group, which red‐shifts the absorption into the visible region and also stabilizes the supramolecular network through π–π interactions. Acid–ether hydrogen bonds are incorporated for energy dissipation under mechanical deformation and maintaining hydrophilicity of the network. This double‐crosslinked supramolecular hydrogel developed via a simple synthesis exhibits a unique combination of high strength, rapid self‐healing, and fast visible‐light‐driven shape morphing both in the wet and dry state. As all of the interactions are dynamic, the design enables the structures to be recycled and reprogrammed into different 3D objects.
Publisher: Elsevier BV
Date: 05-2021
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D1ME00111F
Abstract: Materials with multiple reversible cross-linkers will reassemble during exposure to solvent vapours altering mechanical properties even after drying.
Publisher: American Chemical Society (ACS)
Date: 13-06-2017
Publisher: American Chemical Society (ACS)
Date: 18-12-2023
Abstract: Here, we systematically study the effect of fluorination on the performance of all-polymer solar cells by employing a naphthalene diimide (NDI)-based polymer acceptor with thiophene-flanked phenyl co-monomer. Fluorination of the phenyl co-monomer with either two or four fluorine units is used to create a series of acceptor polymers with either no fluorination (PNDITPhT), bifluorination (PNDITF2T), or tetrafluorination (PNDITF4T). In blends with the donor polymer PTB7-Th, fluorination results in an increase in power conversion efficiency from 3.1 to 4.6% despite a decrease in open-circuit voltage from 0.86 V (unfluorinated) to 0.78 V (tetrafluorinated). Countering this decrease in open-circuit voltage is an increase in short-circuit current from 7.7 to 11.7 mA/cm
Publisher: Wiley
Date: 18-04-2017
Abstract: Well-defined steroid hormone dimers and organogels were produced via a facile and scalable synthesis using oxime click chemistry. The versatile synthetic procedure extends to a wide range of hormones and linker groups exemplified here through the synthesis of cortisol- and progesterone-dimers linked via hydrophobic, hydrophilic or functional groups. This method was also extended to the synthesis of cortisone-based organogels. Owing to the dynamic nature of the oxime bond, the hormone-based materials are degradable via acidic hydrolysis and transoximination representing new materials for the controlled release of steroid hormones.
Publisher: Wiley
Date: 03-02-2023
Abstract: The rapid increase in the use of plastics and the related sustainability issues, including the depletion of global petroleum reserves, have rightly sparked interest in the use of biobased polymer feedstocks. Thermosets cannot be remolded, processed, or recycled, and hence cannot be reused because of their permanent molecular architecture. Vitrimers have emerged as a novel polymer family capable of bridging the difference between thermoplastic and thermosets. Vitrimers enable unique recycling strategies, however, it is still important to understand where the raw material feedstocks originate from. Transesterification vitrimers derived from renewable resources are a massive opportunity, however, limited research has been conducted in this specific family of vitrimers. This review article provides a comprehensive overview of transesterification vitrimers produced from biobased monomers. The focus is on the biomass structural suitability with dynamic covalent chemistry, as well as the viability of the synthetic methods.
Publisher: Wiley
Date: 17-09-2017
DOI: 10.1002/POLA.28856
Publisher: Wiley
Date: 20-10-2015
DOI: 10.1002/POLA.27927
Publisher: Elsevier BV
Date: 06-2017
Publisher: CSIRO Publishing
Date: 2016
DOI: 10.1071/CH16033
Abstract: The aqueous solution self-assembly of a series of poly(2-vinyl pyridine)-block-poly(dimethylsiloxane) (P2VP-b-PDMS) diblock copolymers is reported. The particles show a phase separated interior morphology which can be tuned from onion-like sphere to axially stacked lamella with dimensions in the nanoscale. The key to this transition is the control of the interfacial properties using a mixture of two surfactants with preferential wetting to the respective blocks (P2VP or PDMS). Influence of block weights on particle morphology was investigated with results showing that the volume fraction of PDMS plays a crucial role in self-assembly, and a non-conventional structure of a prolate spheroid nanoparticle with a unique phase separated interior morphology can be synthesised.
Publisher: Elsevier BV
Date: 08-2018
Publisher: American Chemical Society (ACS)
Date: 19-07-2016
DOI: 10.1021/ACS.LANGMUIR.6B00211
Abstract: Xanthate-functional polymers represent an exciting opportunity to provide temperature-responsive materials with the ability to selectively attach to specific metals, while also modifying the lower critical solution temperature (LCST) behavior. To investigate this, random copolymers of poly(N-isopropylacrylamide) (PNIPAM) with xanthate incorporations ranging from 2 to 32% were prepared via free radical polymerization. Functionalization with 2% xanthate increased the LCST by 5 °C relative to the same polymer without xanthate. With increasing xanthate composition, the transition temperature increased and the transition range broadened until a critical composition of the hydrophilic xanthate groups (≥18%) where the transition disappeared completely. The adsorption of the polymers at room temperature onto chalcopyrite (CuFeS2) surfaces increased with xanthate composition, while adsorption onto quartz (SiO2) was negligible. These findings demonstrate the affinity of these functional smart polymers toward copper iron sulfide relative to quartz surfaces, presumably due to the interactions between xanthate and specific metal centers.
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1MA00223F
Abstract: We report a macromolecular design concept to develop humidity-responsive polymers with simultaneously improved mechanical properties and 3D printability, while still displaying fast, reversible and complex shape transformations.
Publisher: Wiley
Date: 05-08-2020
Publisher: Elsevier BV
Date: 2018
Publisher: American Chemical Society (ACS)
Date: 12-10-2016
Abstract: In this work we describe the synthesis, thermal and rheological characterization, hot-melt extrusion, and three-dimensional printing (3DP) of poly(2-vinylpyridine) (P2VP). We investigate the effect of thermal processing conditions on physical properties of produced filaments in order to achieve high quality, 3D-printable filaments for material extrusion 3DP (ME3DP). Mechanical properties and processing performances of P2VP were enhanced by addition of 12 wt % acrylonitrile-butadiene-styrene (ABS), which reinforced P2VP fibers. We 3D-print P2VP filaments using an affordable 3D printer. The pyridine moieties are cross-linked and quaternized postprinting to form 3D-printed pH-responsive hydrogels. The printed objects exhibited dynamic and reversible pH-dependent swelling. These hydrogels act as flow-regulating valves, controlling the flow rate with pH. Additionally, a macroporous P2VP membrane was 3D-printed and the coordinating ability of the pyridyl groups was employed to immobilize silver precursors on its surface. After the reduction of silver ions, the structure was used to catalyze the reduction of 4-nitrophenol to 4-aminophenol with a high efficiency. This is a facile technique to print recyclable catalytic objects.
Publisher: American Chemical Society (ACS)
Date: 20-12-2016
DOI: 10.1021/ACS.BIOMAC.6B01618
Abstract: The copolymerization of N-isopropylacrylamide (NiPAm) with aldehyde functional monomers facilitates postpolymerization functionalization with amino acids via reductive amination, negating the need for protecting groups. In reductive amination, the imine formed from the condensation reaction between an amine and an aldehyde is reduced to an amine. In this work, we categorize amino acids into four classes based on the functionality of their side chains (acidic, polar neutral, neutral, and basic) and use their amine groups in condensation reactions with aldehyde functional polymers. The dynamic nature of the imine as well as the versatility of reductive amination to functionalize a polymer with a range of amino acids is highlighted. In this manner, amino acid functional polymers are synthesized without the use of protecting groups with high yields, demonstrating the high functional group tolerance of carbonyl condensation chemistry and the subsequent reduction of the imine. Prior to the reduction of the imine bond, transimination reactions are used to demonstrate dynamic polymers that shuffle from a glycine- to a histidine-functional polymer.
Publisher: Elsevier BV
Date: 05-2017
DOI: 10.1016/J.JCIS.2017.01.067
Abstract: Temperature-responsive flocculants, such as poly(N-isopropylacrylamide) (PNIPAM), induce reversible particle aggregation upon heating above a lower critical solution temperature (LCST). The aim of this work is to investigate the aggregation of ground iron ore using PNIPAM and conventional polyacrylamide (PAM) flocculants in a continuously-sheared suspension, through in situ chord length measurements using Focused Beam Reflectance Measurement techniques and real-time imaging of the particle aggregates. In the presence of uncharged PNIPAM, particle aggregation occurs only upon heating to the LCST, and the aggregates continue to grow with further heating. Subsequent cooling re-disperses the aggregates, and repeated heating causes reformation. Unlike uncharged PNIPAM, anionic PNIPAM produces aggregates at temperatures below the LCST due to the polymer chains binding to two different particles via attractive interactions between the acrylic acid groups and the hematite surfaces, and can be added at temperatures above the LCST due to the formation of charge-stabilised micelles. Under continuous shear, the flocculant most able to resist aggregate size reduction was anionic PAM, followed by PAM, anionic PNIPAM, PNIPAM (6MDa), and PNIPAM (122kDa). Reversible aggregate breakage was found with all s les, except with PNIPAM (6MDa) after being subjected to shear rates above 550s
Publisher: Elsevier BV
Date: 05-2017
Publisher: Royal Society of Chemistry (RSC)
Date: 2016
DOI: 10.1039/C6PY00372A
Abstract: Extremely rapid step growth polymerization was achieved using an oxime click chemistry approach.
Publisher: American Association for the Advancement of Science (AAAS)
Date: 03-04-2020
Abstract: Enzyme-inspired catalysis using self-assembled hiphiles mimic and localize multiple chemical units common to hydrolases.
Publisher: Wiley
Date: 26-05-2009
Abstract: Fully loaded: Noncovalent anchoring of liposomes into polymer multilayered films with cholesterol-modified polymers allows the preparation of capsosomes-liposome-compartmentalized polymer capsules (see picture). A quantitative enzymatic reaction confirmed the presence of active cargo within the capsosomes and was used to determine the number of subcompartments within this novel biomedical carrier system.
Publisher: American Chemical Society (ACS)
Date: 22-08-2017
DOI: 10.1021/ACS.BIOCONJCHEM.7B00360
Abstract: A dual-responsive, cell capture and release surface was prepared through the incorporation of phenylboronic acid (PBA) groups into an oxime-based polyethylene glycol (PEG) hydrogel. Owing to its PEG-like properties, the unfunctionalized hydrogel was nonfouling. The use of highly efficient oxime chemistry allows the incorporation of commercially available 3,5-diformylphenyl boronic acid into the hydrogel matrix. Thus, the surface properties of the hydrogel were modified to enable reversible cell capture and release. Boronic ester formation between PBA groups and cell surface carbohydrates enabled efficient cell capture at pH 6.8. An increase to pH 7.8 resulted in cell detachment. This capture-and-release procedure was performed on MCF-7 human breast cancer cells, NIH-3T3 fibroblast cells, and primary human umbilical vein endothelial cells (HUVECs) and could be cycled with negligible loss in activity. The facile preparation of PBA-functionalized surfaces presented here has applications in biomedical fields such as cell diagnostics and cell culture.
Publisher: Royal Society of Chemistry (RSC)
Date: 2016
DOI: 10.1039/C6PY00635C
Abstract: The synthesis of new, highly functional and dynamic polymeric materials has risen dramatically since the introduction of click chemistry in 2001.
Publisher: Wiley
Date: 05-02-2021
Publisher: Society for Neuroscience
Date: 26-01-2011
DOI: 10.1523/JNEUROSCI.4085-10.2011
Abstract: There have been many attempts at explaining age-related cognitive decline on the basis of regional brain changes, with the usual but inconsistent findings being that smaller gray matter volumes in certain brain regions predict worse cognitive performance in specific domains. Additionally, compromised white matter integrity, as suggested by white matter hyperintensities or decreased regional white matter fractional anisotropy, has an adverse impact on cognitive functions. The human brain is, however, a network and it may be more appropriate to relate cognitive functions to properties of the network rather than specific brain regions. We report on graph theory-based analyses of diffusion tensor imaging tract-derived connectivity in a s le of 342 healthy in iduals aged 72–92 years. The cognitive domains included processing speed, memory, language, visuospatial, and executive functions. We examined the association of these cognitive assessments with both the connectivity of the whole brain network and in idual cortical regions. We found that the efficiency of the whole brain network of cortical fiber connections had an influence on processing speed and visuospatial and executive functions. Correlations between connectivity of specific regions and cognitive assessments were also observed, e.g., stronger connectivity in regions such as superior frontal gyrus and posterior cingulate cortex were associated with better executive function. Similar to the relationship between regional connectivity efficiency and age, greater processing speed was significantly correlated with better connectivity of nearly all the cortical regions. For the first time, regional anatomical connectivity maps related to processing speed and visuospatial and executive functions in the elderly are identified.
Publisher: Elsevier BV
Date: 10-2016
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C4PY01356E
Abstract: This review highlights antibiofouling polymer interfaces with emphasis on the latest developments using poly(ethylene glycol) and the design new polymeric structures.
Publisher: American Chemical Society (ACS)
Date: 18-01-2023
Publisher: American Chemical Society (ACS)
Date: 30-10-2018
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2CY00744D
Abstract: Self-assembling transesterification catalyst inspired by the catalytic triad.
Publisher: Elsevier BV
Date: 07-2018
Publisher: Royal Society of Chemistry (RSC)
Date: 2023
DOI: 10.1039/D3ME00132F
Start Date: 2018
End Date: 12-2020
Amount: $317,288.00
Funder: Australian Research Council
View Funded ActivityStart Date: 07-2023
End Date: 06-2027
Amount: $1,053,046.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2009
End Date: 04-2010
Amount: $86,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 07-2023
End Date: 06-2026
Amount: $674,004.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2023
End Date: 12-2025
Amount: $418,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2021
End Date: 12-2021
Amount: $289,500.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2020
End Date: 12-2022
Amount: $420,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2019
End Date: 12-2019
Amount: $368,994.00
Funder: Australian Research Council
View Funded Activity