ORCID Profile
0000-0001-9635-5807
Current Organisation
University of Adelaide
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Research Topics
In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Top 5 Research Topics
ANZSRC Field of Research (FoR)
Materials engineering | Catalytic Process Engineering | Chemical Engineering | Nanomaterials | Functional materials | Environmental Nanotechnology | Catalysis and mechanisms of reactions | Macromolecular and materials chemistry not elsewhere classified | Nanomaterials | Chemical engineering | Functional Materials | Reaction engineering (excl. nuclear reactions) | Electrochemical energy storage and conversion
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in Technology | Environmentally Sustainable Energy Activities not elsewhere classified | Expanding Knowledge in the Environmental Sciences | Expanding Knowledge in Engineering | Water Safety |
Related Links
Publications
Platinum single atoms anchored on ultra-thin carbon nitride nanosheets for photoreforming of glucose
Publisher: Elsevier BV
Date: 11-2023
Superstructures with Atomic-Level Arranged Perovskite and Oxide Layers for Advanced Oxidation with an Enhanced Non-Free Radical Pathway
Publisher: American Chemical Society (ACS)
Date: 21-01-2022
Hydroxyl radical dominated elimination of plasticizers by peroxymonosulfate on metal-free boron: Kinetics and mechanisms
Publisher: Elsevier BV
Date: 11-2020
Single platinum atoms anchored on holy carbon nitride for efficient photodegradation of sulfonylurea herbicide
Publisher: Elsevier BV
Date: 10-2022
Author Correction: Divergent mutational processes distinguish hypoxic and normoxic tumours
Publisher: Springer Science and Business Media LLC
Date: 08-12-2022
Roles of structure defect, oxygen groups and heteroatom doping on carbon in nonradical oxidation of water contaminants
Publisher: Elsevier BV
Date: 10-2020
Decorated nickel phosphide nanoparticles with nitrogen and phosphorus co-doped porous carbon for enhanced electrochemical water splitting
Publisher: Elsevier BV
Date: 05-2020
Selective recovery of Gd(III) by benzimidazole- and benzoxazole-linked 3D porous polymers
Publisher: Elsevier BV
Date: 02-2023
Facile assembly of Bi2 O3 /Bi2 S3 /MoS2 n-p heterojunction with layered n-Bi2 O3 and p-MoS2 for enhanced photocatalytic water oxidation and pollutant degradation
Publisher: Elsevier BV
Date: 2017
Crystallinity and valence states of manganese oxides in Fenton-like polymerization of phenolic pollutants for carbon recycling against degradation
Publisher: Elsevier BV
Date: 10-2022
Peroxymonosulfate activation by Fe3O4-MnO2/CNT nanohybrid electroactive filter towards ultrafast micropollutants decontamination: Performance and mechanism
Publisher: Elsevier BV
Date: 02-2022
DOI: 10.1016/J.JHAZMAT.2021.127111
Abstract: Electrocatalytic peroxymonosulfate (PMS) activation is a promising advanced oxidation process for the degradation of micropollutants. Herein, we developed an electroactive carbon nanotube (CNT) filter functionalized with Fe
Metal-free graphene-carbon nitride hybrids for photodegradation of organic pollutants in water
Publisher: Elsevier BV
Date: 12-2015
Manganese‐Based Micro/Nanomotors: Synthesis, Motion, and Applications
Publisher: Wiley
Date: 28-07-2021
Abstract: As emerging micro/nano‐scale devices, micro/nanomotors have been innovatively applied in the environmental and biomedical applications. In this paper, the recent advances of Mn‐based micro/nanomotors (Mn‐micro/nanomotors) in catalytic oxidation of organic contaminants and the mechanisms in decomposition of H 2 O 2 (e.g., the generation of O 2 bubbles and reactive oxygen species) are reviewed. The intrinsic characteristics and synthetic strategies of Mn‐based materials are discussed, aiming to gain comprehensive understandings on the asymmetric design of micro/nanomotors. Mn‐micro/nanomotors have many advantages such as flexible structures, biocompatibility, powerful motion, long lifetime, and low‐cost as compared to noble‐metal micro/nanomotors. These merits fulfil Mn‐micro/nanomotors great promises from proof‐of‐concept studies to realistic applications, including pollutant decomposition, trace detection of heavy metal ions, oil removal, drug delivery, isolation of biological targets, and killing bacteria and cancer cells. The great flexibility in fabrication enables erse and innovative strategies to address challenges for Mn‐micro/nanomotors, including high consumption of H 2 O 2 and non‐directional motion. Meanwhile, a perspective of Mn‐micro/nanomotors in water remediation by coupling the motors with other Fenton/Fenton‐like systems to enhance the catalytic activity and to yield more reactive oxygen species is presented. Directions to the design of on‐demand H 2 O 2 ‐fueled Mn‐micro/nanomotors for advanced purification of organic contaminants in aquatic systems are also proposed.
Facile synthesis of N-doped 3D graphene aerogel and its excellent performance in catalytic degradation of antibiotic contaminants in water
Publisher: Elsevier BV
Date: 04-2019
Rational Regulation of Co-N-C Coordination for High-Efficiency Generation of
Publisher: American Chemical Society (ACS)
Date: 26-05-2022
Abstract: Single oxygen-based advanced oxidation processes (
Structure-dependent catalysis of cuprous oxides in peroxymonosulfate activation via nonradical pathway with a high oxidation capacity
Publisher: Elsevier BV
Date: 03-2020
DOI: 10.1016/J.JHAZMAT.2019.121518
Abstract: Research interests have been recently thrust into the nonradical reactions in persulfate-based advanced oxidation processes (AOPs), whilst the underlying mechanism of the nonradical pathway remains ambiguous especially in metal-based AOPs systems. In this study, we investigated the reactivity of cuprous oxide (Cu
Two−dimensional nanomaterials confined single atoms: New opportunities for environmental remediation
Publisher: Elsevier BV
Date: 03-2023
Iron-doped cuprous oxides toward accelerated nonradical oxidation: Doping induced controlled facet transformation and optimized electronic structure
Publisher: Elsevier BV
Date: 03-2021
Catalytic Pollutant Upgrading to Dual-Asymmetric MnO2@polymer Nanotubes as Self-Propelled and Controlled Micromotors for H2O2 Decomposition
Publisher: Wiley
Date: 06-07-2023
Abstract: Industrial and disinfection wastewater typically contains high levels of organic pollutants and residue hydrogen peroxide, which have caused environmental concerns. In this work, dual‐asymmetric MnO 2 @polymer microreactors are synthesized via pollutant polymerization for self‐driven and controlled H 2 O 2 decomposition. A hollow and asymmetric MnO 2 nanotube is derived from MnO 2 nanorods by selective acid etching and then coated by a polymeric layer from an aqueous phenolic pollutant via catalytic peroxymonosulfate (PMS)‐induced polymerization. The evolution of particle‐like polymers is controlled by solution pH, molar ratios of PMS henol, and reaction duration. The polymer‐covered MnO 2 tubing‐structured micromotors presented a controlled motion velocity, due to the reverse torque driven by the O 2 bubbles from H 2 O 2 decomposition in the inner tunnels. In addition, the partially coated polymeric layer can regulate the exposure and population of Mn active sites to control the H 2 O 2 decomposition rate, thus avoiding violent motions and massive heat caused by vigorous H 2 O 2 decomposition. The microreactors can maintain the function of mobility in an ultra‐low H 2 O 2 environment ( .31 wt.%). This work provides a new strategy for the transformation of micropollutants to functional polymer‐based microreactors for safe and controlled hydrogen peroxide decomposition for environmental remediation.
New insights into heterogeneous generation and evolution processes of sulfate radicals for phenol degradation over one-dimensional α-MnO2 nanostructures
Publisher: Elsevier BV
Date: 04-2015
Structure-oriented conversions of plastics to carbon nanomaterials
Publisher: Springer Science and Business Media LLC
Date: 02-08-2022
DOI: 10.1007/S44246-022-00016-2
Abstract: The accumulation of waste plastics has caused serious environmental issues due to their unbiodegradable nature and hazardous additives. Converting waste plastics to different carbon nanomaterials (CNMs) is a promising approach to minimize plastic pollution and realize advanced manufacturing of CNMs. The reported plastic-derived carbons include carbon filaments (i.e. carbon nanotubes and carbon nanofibers), graphene, carbon nanosheets, carbon sphere, and porous carbon. In this review, we present the influences of different intrinsic structures of plastics on the pyrolysis intermediates. We also reveal that non-charring plastics are prone to being pyrolyzed into light hydrocarbons while charring plastics are prone to being pyrolyzed into aromatics. Subsequently, light hydrocarbons favor to form graphite while aromatics are inclined to form amorphous carbon during the carbon formation process. In addition, the conversion tendency of different plastics into various morphologies of carbon is concluded. We also discuss other impact factors during the transformation process, including catalysts, temperature, processing duration and templates, and reveal how to obtain different morphological CNMs from plastics. Finally, current technology limitations and perspectives are presented to provide future research directions in effective plastic conversion and advanced CNM synthesis.
S-scheme MIL-101(Fe) octahedrons modified Bi2WO6 microspheres for photocatalytic decontamination of Cr(VI) and tetracycline hydrochloride: Synergistic insights, reaction pathways, and toxicity analysis
Publisher: Elsevier BV
Date: 2023
Enhanced solar light driven activity of p-n heterojunction for water oxidation induced by deposition of Cu2O on Bi2O3 microplates
Publisher: Elsevier BV
Date: 04-2019
The double-edged effect of single atom metals on photocatalysis
Publisher: Elsevier BV
Date: 02-2023
Photocatalytic activation of peroxymonosulfate by carbon quantum dots: rational regulation of surface functionality and computational insights
Publisher: Elsevier BV
Date: 06-2023
Fine-Tuning Radical/Nonradical Pathways on Graphene by Porous Engineering and Doping Strategies
Publisher: American Chemical Society (ACS)
Date: 06-04-2021
Unveiling the Relationship of Surface Roughness on Superliquid-Repelling Properties with Randomly Distributed Rough Surface Structures
Publisher: American Chemical Society (ACS)
Date: 10-10-2022
DOI: 10.1021/ACS.LANGMUIR.2C01778
Abstract: Though superliquid-repelling surfaces are universally important in the fields of fundamental research and industrial production, the understanding and development of these surfaces to impacting liquid droplets remain elusive, especially the changes of wettability states. Surface roughness is required to obtain superliquid-repelling surfaces. However, the effect of surface roughness on the transition of these surfaces' wettability states is uncertain. Herein, we unveiled the relationship of surface roughness on regulating the wettability states of superliquid-repelling surfaces with randomly distributed rough structures through experiment and calculations. The roughness was controlled via regulating the size of surface rough structures, which were formed by a facile coating method. The results indicated that the surface rough structures could impact the value of the polar component (γ
The Nature of Active Sites for Plasmon‐Mediated Photothermal Catalysis and Heat‐Coupled Photocatalysis in Dry Reforming of Methane
Publisher: Wiley
Date: 30-01-2023
DOI: 10.1002/EEM2.12416
Abstract: Solar energy‐induced catalysis has been attracting intensive interests and its quantum efficiencies in plasmon‐mediated photothermal catalysis (P‐photothermal catalysis) and external heat‐coupled photocatalysis (E‐photothermal catalysis) are ultimately determined by the catalyst structure for photo‐induced energetic hot carriers. Herein, different catalysts of supported (TiO 2 ‐P25 and Al 2 O 3 ) platinum quantum dots are employed in photo, thermal, and photothermal catalytic dry reforming of methane. Integrated experimental and computational results unveil different active sites (hot zones) on the two catalysts for photo, thermal, and photothermal catalysis. The hot zones of P‐photothermal catalysis are identified to be the metal–support interface on Pt/P25 and the Pt surface on Pt/Al 2 O 3 , respectively. However, a change of the active site to the Pt surface on Pt/P25 is for the first time observed in E‐photothermal catalysis (external heating temperature of 700 °C). The hot zones contribute to the significant enhancements in photothermal catalytic reactivity against thermocatalysis. This study helps to understand the reaction mechanism of photothermal catalysis to exploit efficient catalysts for solar energy utilization and fossil fuels upgrading.
Electro-Induced Carbon Nanotube Discrete Electrodes for Sustainable Persulfate Activation
Publisher: American Chemical Society (ACS)
Date: 05-09-2022
Abstract: In electrochemical advanced oxidation processes (EAOPs), the rate-limiting step is the mass transfer of pollutants to the electrodes due to the limited active surface areas. To this end, we established a three-dimensional (3D) EAOP system by coupling conventional graphite electrodes with dispersed carbon nanotubes (CNTs). The electrodes (particularly the anode) induced electric field spontaneously polarized CNTs into dispersed reactive particle electrodes (CNT-PEs) in the solution, which remarkably promoted electrochemical activation of peroxydisulfate (PDS) to generate surface CNT-PDS* complexes and surface-bound radicals (SBRs). Based on the excited potential (
Polyaniline-decorated porous carbons with engineered meso/macrochannels for high performance capacitive deionization
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2TA07929A
Abstract: Polyaniline modified activated carbon shows outstanding capacitive deionization ability because of the synergism between electrical double layer adsorption and pseudocapacitive deionization.
Author Correction: Integrative pathway enrichment analysis of multivariate omics data
Publisher: Springer Science and Business Media LLC
Date: 08-12-2022
van der Waals type II carbon nitride homojunctions for visible light photocatalytic hydrogen evolution
Publisher: Springer Science and Business Media LLC
Date: 05-08-2021
In-plane implanting carbon rings into carbon nitride to intrigue nonradical photodegradation
Publisher: Elsevier BV
Date: 03-2024
Low temperature combustion synthesis of nitrogen-doped graphene for metal-free catalytic oxidation
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C4TA05940A
Abstract: A mild synthesis method was developed to improve metal-free catalysis of graphene in catalytic oxidation by nitrogen modification, which can be easily tailored by varying calcination temperature.
Graphitic Carbon Nitride-Based Z-Scheme Structure for Photocatalytic CO2 Reduction
Publisher: American Chemical Society (ACS)
Date: 03-11-2020
Municipal solid waste derived biochars for wastewater treatment: Production, properties and applications
Publisher: Elsevier BV
Date: 02-2022
Insights into perovskite-catalyzed peroxymonosulfate activation: Maneuverable cobalt sites for promoted evolution of sulfate radicals
Publisher: Elsevier BV
Date: 10-2011
High-Efficiency Fe (Iii)-Doped Ultrathin Vo2 Nanobelts Boosted Peroxydisulfate Activation for Actual Antibiotics Photodegradation
Publisher: Elsevier BV
Date: 2023
DOI: 10.2139/SSRN.4611821
Novel applications of perovskite oxide via catalytic peroxymonosulfate advanced oxidation in aqueous systems for trace L-cysteine detection
Publisher: Elsevier BV
Date: 06-2019
DOI: 10.1016/J.JCIS.2019.03.045
Abstract: Perovskite oxides offer new opportunities in wastewater treatment via catalytic oxidation. Herein, we report a new application of perovskite oxides for biological detection via catalytic decolourisation and colorimetric determination. The presence of trace biomolecules in an aqueous system would interfere the decolourisation process of dyes, where the decolourisation rate is quantitatively correlated to the biomolecular concentration. In this work, trace L-cysteine (Cys) detection was demonstrated on the basis of a Ag-Ba
High-performance photocatalytic peroxymonosulfate activation by carbon quantum dots via precise surface chemistry regulation: Insight into the structure–function relations
Publisher: Elsevier BV
Date: 09-2023
Molecular and kinetic insights to boron boosted Fenton-like activation of peroxymonosulfate for water decontamination
Publisher: Elsevier BV
Date: 12-2022
Graphitic nitride-catalyzed advanced oxidation processes (AOPs) for landfill leachate treatment: A mini review
Publisher: Elsevier BV
Date: 07-2020
Temperature-dependent evolution of hydroxyl radicals from peroxymonosulfate activation over nitrogen-modified carbon nanotubes
Publisher: Elsevier BV
Date: 12-2018
Visible-light activation of persulfate ions by Z-scheme perylene diimide/MIL-101(Cr) heterojunction photocatalyst towards efficient degradation of iohexol
Publisher: Elsevier BV
Date: 05-2022
Metal-free and oxidizing agent-free ultra-selective catalytic aerobic conversion of vanillyl alcohol to vanillin by carbon fiber
Publisher: Elsevier BV
Date: 11-2022
Boosting performance of lanthanide magnetism perovskite for advanced oxidation through lattice doping with catalytically inert element
Publisher: Elsevier BV
Date: 2019
Insight into the effect of lignocellulosic biomass source on the performance of biochar as persulfate activator for aqueous organic pollutants remediation: Epicarp and mesocarp of citrus peels as examples
Publisher: Elsevier BV
Date: 11-2020
Peroxymonosulfate oxidation via paralleled nonradical pathways over iron and nitrogen doped porous carbons
Publisher: Elsevier BV
Date: 08-2022
DOI: 10.1016/J.SCITOTENV.2022.155670
Abstract: Hierarchically porous iron/nitrogen-doped carbons (Fe-N-PC) were developed for the oxidation of ibuprofen (IBP) with peroxymonosulfate (PMS). The incorporation of trace-level iron and nitrogen dopants promoted the catalytic performance remarkably, leading to 4.8, 16.4 and 22.9-fold enhancement over N-doped carbon (N-PC), porous carbon (PC), and Fe-doped carbon (Fe-PC), respectively. Fe(III) was anchored in nitrogen-coordinated pots (Fe-N
Improving the Structure Stability of LiNi0.8Co0.15Al0.05O2 by Double Modification of Tantalum Surface Coating and Doping
Publisher: American Chemical Society (ACS)
Date: 10-08-2021
Surface-tailored nanodiamonds as excellent metal-free catalysts for organic oxidation
Publisher: Elsevier BV
Date: 07-2016
UV-assisted construction of 3D hierarchical rGO/Bi2 MoO6 composites for enhanced photocatalytic water oxidation
Publisher: Elsevier BV
Date: 04-2017
Functional Carbon Nitride Materials in Photo‐Fenton‐Like Catalysis for Environmental Remediation
Publisher: Wiley
Date: 12-05-2022
Abstract: Among various advanced oxidation processes, coupled photocatalysis and heterogeneous Fenton‐like catalysis (known as photo‐Fenton‐like catalysis) to generate highly reactive species for environmental remediation has attracted wide interests. As an emerging metal‐free photocatalyst, graphitic carbon nitride (g‐C 3 N 4 , CN) has been recently recognized as a promising candidate to catalyze robustly heterogeneous photo‐Fenton‐like reactions for wastewater remediation. This review summarizes recent progress in fabricating various types of CN‐based catalysts for the photo‐Fenton‐like reaction process. Innovative engineering strategies on the CN matrix are outlined, ranging from morphology control, defect engineering, nonmetal atom doping, organic molecule doping to modification by metal‐containing species. The photo‐Fenton‐like catalytic activities of CN loaded with auxiliary sub‐nanoscale (e.g., quantum dots, organometallic molecules, metal cations, and single atom metals) and nanoscale metal‐based materials are critically evaluated. Hybridization of CN with bandgap‐matching semiconductors for the construction of type‐II and Z‐scheme heterojunctions are also examined. The critical factors (e.g., morphology, dimensionality, light absorption, charge excitation/migration, catalytic sites, H 2 O 2 generation and activation) that determine the performance of CN‐based photocatalysts in Fenton‐like catalysis are systematically discussed. After examining the structure–activity relationship, research perspectives are proposed for further development of CN‐based photocatalysts toward more efficient photo‐Fenton‐like reactions and their application in practical water treatment.
Interfacial CoAl2O4 from ZIF-67@γ-Al2O3 pellets toward catalytic activation of peroxymonosulfate for metronidazole removal
Publisher: Elsevier BV
Date: 10-2020
Cobalt silicate hydroxide nanosheets in hierarchical hollow architecture with maximized cobalt active site for catalytic oxidation
Publisher: Elsevier BV
Date: 03-2019
Merits and Limitations of Radical vs. Nonradical Pathways in Persulfate-Based Advanced Oxidation Processes
Publisher: American Chemical Society (ACS)
Date: 03-08-2023
Redox-Active Polymers as Robust Electron-Shuttle Co-Catalysts for Fast Fe3+/Fe2+ Circulation and Green Fenton Oxidation
Publisher: American Chemical Society (ACS)
Date: 03-02-2023
Cobalt porphyrins supported on carbon nanotubes as model catalysts of metal-N4/C sites for oxygen electrocatalysis
Publisher: Elsevier BV
Date: 02-2020
Regulating energy band structures of triazine covalent organic frameworks with electron-donating/withdrawing substituents for visible-light-responsive photocatalytic tetracycline degradation and Cr(VI) reduction
Publisher: Elsevier BV
Date: 03-2023
New insight to the role of edges and heteroatoms in nanocarbons for oxygen reduction reaction
Publisher: Elsevier BV
Date: 12-2019
Engineered Co2AlO4/CoAl2O4@Al2O3 monolithic catalysts for peroxymonosulfate activation: Co3+/Co2+ and ODefect/OLattice ratios dependence and mechanism
Publisher: Elsevier BV
Date: 04-2021
Manganese oxide integrated catalytic ceramic membrane for degradation of organic pollutants using sulfate radicals
Publisher: Elsevier BV
Date: 12-2019
DOI: 10.1016/J.WATRES.2019.115110
Abstract: Membrane separation and advanced oxidation processes (AOPs) have been respectively demonstrated to be effective for a variety of water and/or wastewater treatments. Innovative integration of membrane with catalytic oxidation is thus expected to be more competing for more versatile applications. In this study, ceramic membranes (CMs) integrated with manganese oxide (MnO
Thermodynamic and Kinetic Behaviors of Persulfate-Based Electron-Transfer Regime in Carbocatalysis
Publisher: American Chemical Society (ACS)
Date: 20-08-2023
Synchronous removal of emulsions and soluble organic contaminants via a microalgae-based membrane system: performance and mechanisms
Publisher: Elsevier BV
Date: 11-2021
The structure-dependent mechanism of single-atom cobalt on macroporous carbon nitride in (photo-)Fenton-like reactions
Publisher: Royal Society of Chemistry (RSC)
Date: 2023
DOI: 10.1039/D3TA01926H
Abstract: Ordered macroporous carbon nitride supported single-atom Co catalysts with Co–N 1+3 /Co–N 2+2 geometric structures are developed using a spatial confinement strategy for (photo-)Fenton-like catalytic reactions.
Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer
Publisher: Springer Science and Business Media LLC
Date: 08-12-2022
Nitrogen-doped carbon nanotubes enhanced Fenton chemistry: Role of near-free iron(III) for sustainable iron(III)/iron(II) cycles
Publisher: Elsevier BV
Date: 02-2022
DOI: 10.1016/J.WATRES.2021.117984
Abstract: The sluggish kinetics of Fe(II) recovery strongly impedes the scientific progress of Fenton reaction (Fe(II)/H
Converting waste plastics into construction applications: A business perspective
Publisher: Elsevier BV
Date: 09-2022
Sub-5 nm Ultra-Fine FeP Nanodots as Efficient Co-Catalysts Modified Porous g-C3N4 for Precious-Metal-Free Photocatalytic Hydrogen Evolution under Visible Light
Publisher: American Chemical Society (ACS)
Date: 07-01-2019
Abstract: Sub-5 nm ultra-fine iron phosphide (FeP) nano-dots-modified porous graphitic carbon nitride (g-C
Nanodiamonds in sp2/sp3 configuration for radical to nonradical oxidation
Publisher: Elsevier BV
Date: 03-2018
Manipulation of n → π* electronic transitions via implanting thiophene rings into two-dimensional carbon nitride nanosheets for efficient photocatalytic water purification
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2TA04975A
Abstract: Thiophene ring implanted two-dimensional carbon nitride nanosheets (2D Th ing -CNNS) with dramatically double elevated n → π* electronic transitions were synthesized. 2D Th ing -CNNS exhibited efficient photocatalytic bisphenol-A degradation.
Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower
Publisher: Springer Science and Business Media LLC
Date: 08-12-2022
Regulation of energetic hot carriers on Pt/TiO2 with thermal energy for photothermal catalysis
Publisher: Elsevier BV
Date: 07-2022
Divergent mutational processes distinguish hypoxic and normoxic tumours
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41467-019-14052-X
Abstract: Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular hallmarks of tumour hypoxia remain poorly understood, with limited comprehension of its associations with specific mutational processes, non-coding driver genes and evolutionary features. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we quantify hypoxia in 1188 tumours spanning 27 cancer types. Elevated hypoxia associates with increased mutational load across cancer types, irrespective of underlying mutational class. The proportion of mutations attributed to several mutational signatures of unknown aetiology directly associates with the level of hypoxia, suggesting underlying mutational processes for these signatures. At the gene level, driver mutations in TP53 , MYC and PTEN are enriched in hypoxic tumours, and mutations in PTEN interact with hypoxia to direct tumour evolutionary trajectories. Overall, hypoxia plays a critical role in shaping the genomic and evolutionary landscapes of cancer.
Author Correction: Genomic basis for RNA alterations in cancer
Publisher: Springer Science and Business Media LLC
Date: 25-01-2023
Recent advances in molybdenum disulfide-based advanced oxidation processes
Publisher: Elsevier BV
Date: 03-2022
HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer
Publisher: Elsevier BV
Date: 05-2020
Single-atom co sites confined in layered double hydroxide for selective generation of surface-bound radicals via peroxymonosulfate activation
Publisher: Elsevier BV
Date: 2024
Nitrogen-doped graphene for generation and evolution of reactive radicals by metal-free catalysis
Publisher: American Chemical Society (ACS)
Date: 09-02-2015
DOI: 10.1021/AM508416N
Abstract: N-Doped graphene (NG) nanomaterials were synthesized by directly annealing graphene oxide (GO) with a novel nitrogen precursor of melamine. A high N-doping level, 8-11 at. %, was achieved at a moderate temperature. The s le of NG-700, obtained at a calcination temperature of 700 °C, showed the highest efficiency in degradation of phenol solutions by metal-free catalytic activation of peroxymonosulfate (PMS). The catalytic activity of the N-doped rGO (NG-700) was about 80 times higher than that of undoped rGO in phenol degradation. Moreover, the activity of NG-700 was 18.5 times higher than that of the most popular metal-based catalyst of nanocrystalline Co3O4 in PMS activation. Theoretical calculations using spin-unrestricted density functional theory (DFT) were carried out to probe the active sites for PMS activation on N-doped graphene. In addition, experimental detection of generated radicals using electron paramagnetic resonance (EPR) and competitive radical reactions was performed to reveal the PMS activation processes and pathways of phenol degradation on nanocarbons. It was observed that both (•)OH and SO4(•-) existed in the oxidation processes and played critical roles for phenol oxidation.
Lost in translation: Returning germline genetic results in genome-scale cancer research
Publisher: Springer Science and Business Media LLC
Date: 28-04-2017
Metal-organic frameworks (MOFs) as efficient catalysts for electro-Fenton (EF) reactions: Current progress and prospects
Publisher: Elsevier BV
Date: 05-2023
Landfill leachate treatment by persulphate related advanced oxidation technologies
Publisher: Elsevier BV
Date: 09-2021
Identification and Regulation of Active Sites on Nanodiamonds: Establishing a Highly Efficient Catalytic System for Oxidation of Organic Contaminants
Publisher: Wiley
Date: 17-01-2018
Biomass-derived functional porous carbons for adsorption and catalytic degradation of binary micropollutants in water
Publisher: Elsevier BV
Date: 05-2020
DOI: 10.1016/J.JHAZMAT.2019.121881
Abstract: The biomass, bottlebrush flower, is exploited for the preparation of functionalized porous carbons by one-pot thermal activation using NaHCO
Facet- and defect-dependent activity of perovskites in catalytic evolution of sulfate radicals
Publisher: Elsevier BV
Date: 09-2020
Graphitic biochar catalysts from anaerobic digestion sludge for nonradical degradation of micropollutants and disinfection
Publisher: Elsevier BV
Date: 03-2020
Unzipping carbon nanotubes to nanoribbons for revealing the mechanism of nonradical oxidation by carbocatalysis
Publisher: Elsevier BV
Date: 11-2020
Selective removal of ultrafine suspended solids during organic pollutant degradation by a MoS2/graphene oxide sponge
Publisher: Elsevier BV
Date: 05-2023
Photocatalytic conversion of lignocellulosic biomass to valuable products
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9GC01728C
Abstract: This review summarizes the state-of-the-art accomplishments in photocatalytic conversion of lignocellulosic biomass and its derivatives.
Tuning nanostructured CuCo2O4 on 3D macro-support for enhanced degradation of carbofuran via catalytic activation monopersulfate: Key roles of morphology and active species
Publisher: Elsevier BV
Date: 03-2023
Temperature-Induced Variations in Photocatalyst Properties and Photocatalytic Hydrogen Evolution: Differences in UV, Visible, and Infrared Radiation
Publisher: American Chemical Society (ACS)
Date: 23-04-2021
A novel electrocatalytic filtration system with carbon nanotube supported nanoscale zerovalent copper toward ultrafast oxidation of organic pollutants
Publisher: Elsevier BV
Date: 04-2021
Sustainable redox processes induced by peroxymonosulfate and metal doping on amorphous manganese dioxide for nonradical degradation of water contaminants
Publisher: Elsevier BV
Date: 06-2021
Perspectives of Wood-Inspired Electro-Fenton Catalysis for Energy-Efficient Wastewater Decontamination
Publisher: American Chemical Society (ACS)
Date: 16-10-2023
Genomic analyses identify molecular subtypes of pancreatic cancer
Publisher: Springer Science and Business Media LLC
Date: 24-02-2016
DOI: 10.1038/NATURE16965
Abstract: Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 pathways: KRAS, TGF-β, WNT, NOTCH, ROBO/SLIT signalling, G1/S transition, SWI-SNF, chromatin modification, DNA repair and RNA processing. Expression analysis defined 4 subtypes: (1) squamous (2) pancreatic progenitor (3) immunogenic and (4) aberrantly differentiated endocrine exocrine (ADEX) that correlate with histopathological characteristics. Squamous tumours are enriched for TP53 and KDM6A mutations, upregulation of the TP63∆N transcriptional network, hypermethylation of pancreatic endodermal cell-fate determining genes and have a poor prognosis. Pancreatic progenitor tumours preferentially express genes involved in early pancreatic development (FOXA2/3, PDX1 and MNX1). ADEX tumours displayed upregulation of genes that regulate networks involved in KRAS activation, exocrine (NR5A2 and RBPJL), and endocrine differentiation (NEUROD1 and NKX2-2). Immunogenic tumours contained upregulated immune networks including pathways involved in acquired immune suppression. These data infer differences in the molecular evolution of pancreatic cancer subtypes and identify opportunities for therapeutic development.
Biorenewable Nanocomposite Materials for Wastewater Treatment
Publisher: American Chemical Society
Date: 24-03-2022
Metal-free activation of persulfate by cubic mesoporous carbons for catalytic oxidation via radical and nonradical processes
Publisher: Elsevier BV
Date: 06-2018
The mechanistic difference of 1T-2H MoS2 homojunctions in persulfates activation: Structure-dependent oxidation pathways
Publisher: Elsevier BV
Date: 11-2021
Postsynthesis Oxygen Nonstoichiometric Regulation: A New Strategy for Performance Enhancement of Perovskites in Advanced Oxidation
Publisher: American Chemical Society (ACS)
Date: 11-12-2020
Biochar cathode: Reinforcing electro-Fenton pathway against four-electron reduction by controlled carbonization and surface chemistry
Publisher: Elsevier BV
Date: 02-2021
Integrative pathway enrichment analysis of multivariate omics data
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41467-019-13983-9
Abstract: Multi-omics datasets represent distinct aspects of the central dogma of molecular biology. Such high-dimensional molecular profiles pose challenges to data interpretation and hypothesis generation. ActivePathways is an integrative method that discovers significantly enriched pathways across multiple datasets using statistical data fusion, rationalizes contributing evidence and highlights associated genes. As part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumor types, we integrated genes with coding and non-coding mutations and revealed frequently mutated pathways and additional cancer genes with infrequent mutations. We also analyzed prognostic molecular pathways by integrating genomic and transcriptomic features of 1780 breast cancers and highlighted associations with immune response and anti-apoptotic signaling. Integration of ChIP-seq and RNA-seq data for master regulators of the Hippo pathway across normal human tissues identified processes of tissue regeneration and stem cell regulation. ActivePathways is a versatile method that improves systems-level understanding of cellular organization in health and disease through integration of multiple molecular datasets and pathway annotations.
Impacts and mitigation measures of plastic waste: A critical review
Publisher: Elsevier BV
Date: 09-2021
Directional and Ultrafast Charge Transfer in Oxygen‐Vacancy‐Rich ZnO@Single‐Atom Cobalt Core‐Shell Junction for Photo‐Fenton‐Like Reaction
Publisher: Wiley
Date: 20-06-2023
Abstract: In photosynthesis, solar energy is harvested by photosensitizers, and then, the excited electrons transfer via a Z‐Scheme mode to enzymatic catalytic centers to trigger redox reactions. Herein, we constructed a core–shell Z‐scheme heterojunction of semiconductor@single‐atom catalysts (SACs). The oxygen‐vacancy‐rich ZnO core and single‐atom Co−N 4 sites supported on nitrogen‐rich carbon shell (SA‐Co‐CN) act as the photosensitizer and the enzyme‐mimicking active centers, respectively. Driven by built‐in electric field across the heterojunction, photoexcited electrons could rapidly (2 ps) transfer from the n ‐type ZnO core to the p ‐type SA‐Co‐CN shell, finally boosting the catalytic performance of the surface‐exposed single‐atom Co−N 4 sites for peroxymonosulfate (PMS) activation under light irradiation. The synergies between photocatalysis and heterogeneous Fenton‐like reaction lead to phenomenally enhanced production of various reactive oxygen species for rapid degradation of various microcontaminants in water. Experimental and theoretical results validate that the interfacial coupling of SA‐Co‐CN with ZnO greatly facilitates PMS adsorption and activation by reducing the adsorption energy and enhancing the cascade electron transfer processes for the photo‐Fenton‐like reaction.
Ultrafine copper nanoclusters and single sites for Fenton-like reactions with high atom utilities
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0EN00505C
Abstract: Fenton-like degradation of p -hydroxybenzoic acid by ultrafine copper nanoclusters and single sites exhibited high atom utilities and a wide working pH range.
Origins of boron catalysis in peroxymonosulfate activation and advanced oxidation
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9TA04885E
Abstract: Amorphous boron is employed as a novel and high-performance metal-free catalyst for activation of peroxymonosulfate for degrading various organic contaminants in water.
S-scheme photocatalysis induced by ultrathin TiO2(B) nanosheets-anchored hierarchical In2S3 spheres for boosted photocatalytic activity
Publisher: Elsevier BV
Date: 08-2022
Postsynthesis Growth of CoOOH Nanostructure on SrCo0.6Ti0.4O3-δ Perovskite Surface for Enhanced Degradation of Aqueous Organic Contaminants
Publisher: American Chemical Society (ACS)
Date: 10-2018
Patterns of somatic structural variation in human cancer genomes
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41586-019-1913-9
Abstract: A key mutational process in cancer is structural variation, in which rearrangements delete, lify or reorder genomic segments that range in size from kilobases to whole chromosomes 1–7 . Here we develop methods to group, classify and describe somatic structural variants, using data from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA), which aggregated whole-genome sequencing data from 2,658 cancers across 38 tumour types 8 . Sixteen signatures of structural variation emerged. Deletions have a multimodal size distribution, assort unevenly across tumour types and patients, are enriched in late-replicating regions and correlate with inversions. Tandem duplications also have a multimodal size distribution, but are enriched in early-replicating regions—as are unbalanced translocations. Replication-based mechanisms of rearrangement generate varied chromosomal structures with low-level copy-number gains and frequent inverted rearrangements. One prominent structure consists of 2–7 templates copied from distinct regions of the genome strung together within one locus. Such cycles of templated insertions correlate with tandem duplications, and—in liver cancer—frequently activate the telomerase gene TERT . A wide variety of rearrangement processes are active in cancer, which generate complex configurations of the genome upon which selection can act.
Piezoelectric activation of peroxymonosulfate by MoS2 nanoflowers for the enhanced degradation of aqueous organic pollutants
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D0EN01237H
Abstract: MoS 2 NFs have exhibited abundant active sites in odd-number layers to piezoelectrically activate PMS for producing ˙OH and SO 4 ˙ − in order to degrade organic pollutants.
Magnetic nitrogen-doped nanocarbons for enhanced metal-free catalytic oxidation: Integrated experimental and theoretical investigations for mechanism and application
Publisher: Elsevier BV
Date: 12-2018
Three-dimensional BiOI/BiOX (X = Cl or Br) nanohybrids for enhanced visible-light photocatalytic activity
Publisher: MDPI AG
Date: 14-03-2017
DOI: 10.3390/NANO7030064
Revisiting the Graphitized Nanodiamond-Mediated Activation of Peroxymonosulfate: Singlet Oxygenation versus Electron Transfer
Publisher: American Chemical Society (ACS)
Date: 11-10-2021
Abstract: Graphitized nanodiamonds (ND) exhibit outstanding capability in activating peroxymonosulfate (PMS) for the removal of aqueous organic micropollutants (OMPs). However, controversial observation and interpretation regarding the effect of graphitization degree on ND's activity and the role of singlet oxygen (
Stratified Medicine for Pancreatic Cancer
Publisher: Elsevier
Date: 2014
Prussian blue analogues as heterogeneous catalysts for hydrogen generation from hydrolysis of sodium borohydride: a comparative study
Publisher: Springer Science and Business Media LLC
Date: 04-09-2020
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41467-019-13825-8
Abstract: In cancer, the primary tumour’s organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium , we train a deep learning classifier to predict cancer type based on patterns of somatic passenger mutations detected in whole genome sequencing (WGS) of 2606 tumours representing 24 common cancer types produced by the PCAWG Consortium. Our classifier achieves an accuracy of 91% on held-out tumor s les and 88% and 83% respectively on independent primary and metastatic s les, roughly double the accuracy of trained pathologists when presented with a metastatic tumour without knowledge of the primary. Surprisingly, adding information on driver mutations reduced accuracy. Our results have clinical applicability, underscore how patterns of somatic passenger mutations encode the state of the cell of origin, and can inform future strategies to detect the source of circulating tumour DNA.
Pancreatic cancer genomics: Where can the science take us?
Publisher: Wiley
Date: 19-01-2015
DOI: 10.1111/CGE.12536
Size-tailored porous spheres of manganese oxides for catalytic oxidation via peroxymonosulfate activation
Publisher: American Chemical Society (ACS)
Date: 19-07-2016
New insight into carbon materials enhanced Fenton oxidation: A strategy for green iron(III)/iron(II) cycles
Publisher: Elsevier BV
Date: 12-2022
Unification of hot spots and catalytic sites on isolated boron centers in porous carbon nitride nanosheets for efficient photocatalytic oxygen evolution
Publisher: Elsevier BV
Date: 11-2023
Nanocarbon-Based Catalytic Ozonation for Aqueous Oxidation: Engineering Defects for Active Sites and Tunable Reaction Pathways
Publisher: American Chemical Society (ACS)
Date: 03-11-2020
Mechanical agitation accelerated ultrasonication for wastewater treatment: Sustainable production of hydroxyl radicals
Publisher: Elsevier BV
Date: 06-2021
Synergistic Adsorption and Oxidation of Ciprofloxacin by Biochar Derived from Metal-Enriched Phytoremediation Plants: Experimental and Computational Insights
Publisher: American Chemical Society (ACS)
Date: 18-11-2020
Facile fabrication of 3D ferrous ion crosslinked graphene oxide hydrogel membranes for excellent water purification
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9EN00638A
Abstract: 3D graphene-based macrostructures have been recognized as promising candidates for adsorption and separation of water pollutants due to their well-defined porous structures and high surface areas.
Persulfate Oxidation of Sulfamethoxazole by Magnetic Iron-Char Composites via Nonradical Pathways: Fe(IV) Versus Surface-Mediated Electron Transfer
Publisher: American Chemical Society (ACS)
Date: 02-07-2021
Highly dispersive Ru confined in porous ultrathin g-C3N4 nanosheets as an efficient peroxymonosulfate activator for removal of organic pollutants
Publisher: Elsevier BV
Date: 08-2022
DOI: 10.1016/J.JHAZMAT.2022.128939
Abstract: Ru species were loaded on a two-dimensional (2D) material of graphitic carbon nitride (2D g-C
0D (MoS2 )/2D (g-C3 N4 ) heterojunctions in Z-scheme for enhanced photocatalytic and electrochemical hydrogen evolution
Publisher: Elsevier BV
Date: 07-2018
Unveiling the active sites of graphene-catalyzed peroxymonosulfate activation
Publisher: Elsevier BV
Date: 10-2016
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
Publisher: Springer Science and Business Media LLC
Date: 11-2017
DOI: 10.1038/NATURE24462
Selective Removal of Organic Pollutants in Groundwater and Surface Water by Persulfate-Assisted Advanced Oxidation: The Role of Electron-Donating Capacity
Publisher: American Chemical Society (ACS)
Date: 28-08-2023
Nonradical reactions in environmental remediation processes: Uncertainty and challenges
Publisher: Elsevier BV
Date: 05-2018
Author Correction: Patterns of somatic structural variation in human cancer genomes
Publisher: Springer Science and Business Media LLC
Date: 25-01-2023
Emerging microplastics in the environment: Properties, distributions, and impacts
Publisher: Elsevier BV
Date: 06-2022
DOI: 10.1016/J.CHEMOSPHERE.2022.134118
Abstract: Microplastics (MPs) are emerging and recalcitrant micropollutants in the environment, which have attracted soaring interests from a wide range of research disciplines. To this end, numerous technologies have been devised to understand the properties, environmental behaviors, and potential impacts/hazards of MPs. Herein, we present a review on the properties, environmental distribution and possible impacts. In this review, a comprehensive introduction of the most universal types of MPs, their shapes and characters will be first presented. Then the distributions of MPs in the environment and the impacts on microbe, plants, and human will be reported. Finally, major challenges and directions will be discussed to provide some clues to the better understanding, control and migration of MPs pollution in future studies.
Functional carbon nitride materials for water oxidation: from heteroatom doping to interface engineering
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0NR00652A
Abstract: Strategies for modifying polymeric carbon nitrides and their intrinsic structure–activity relationships for photo-, electro-, and photoelectro-chemical water oxidation are discussed.
Porous Carbons: Structure-Oriented Design and Versatile Applications
Publisher: Wiley
Date: 24-02-2020
Shape-controlled Co3O4 catalysts for advanced oxidation of phenolic contaminants in aqueous solutions
Publisher: Elsevier BV
Date: 10-2017
Oxidation of amines and their derivatives with persulfate without activation: Impact of mineral oxides and stoichiometric efficiency
Publisher: Elsevier BV
Date: 12-2021
Biomass-derived pyrolytic carbons accelerated Fe(III)/Fe(II) redox cycle for persulfate activation: Pyrolysis temperature-depended performance and mechanisms
Publisher: Elsevier BV
Date: 11-2021
Carbon-based single atom catalyst: Synthesis, characterization, DFT calculations
Publisher: Elsevier BV
Date: 02-2022
ACS ES&T Engineering’s 2022 Excellence in Review Awards
Publisher: American Chemical Society (ACS)
Date: 11-08-2023
Catalysis of a Single Transition Metal Site for Water Oxidation: From Mononuclear Molecules to Single Atoms
Publisher: Wiley
Date: 03-12-2019
Abstract: Low-cost, nonprecious transition metal (TM) catalysts toward efficient water oxidation are of critical importance to future sustainable energy technologies. The advances in structure engineering of water oxidation catalysts (WOCs) with single TM centers as active sites, for ex le, single metallic molecular complexes (SMMCs), supported SMMCs, and single-atom catalysts (SACs) in recent reports are examined. The efforts made on these configurations in terms of design principle, advanced characterization, performances and theoretical studies, are critically reviewed. A clear roadmap with the correlations between the single-TM-site-based structures (coordination and geometric structure, TM species, support), and the catalytic performances in water oxidation is provided. The insights bridging SMMCs with SACs are also given. Finally, the challenges and opportunities in the single-TM-site catalysis are proposed.
High-performance photocatalytic decomposition of PFOA by BiOX/TiO2 heterojunctions: Self-induced inner electric fields and band alignment
Publisher: Elsevier BV
Date: 05-2022
DOI: 10.1016/J.JHAZMAT.2021.128195
Abstract: BiOX (X = Cl, Br and I) and BiOX/TiO
The repertoire of mutational signatures in human cancer
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41586-020-1943-3
Abstract: Somatic mutations in cancer genomes are caused by multiple mutational processes, each of which generates a characteristic mutational signature 1 . Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium 2 of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA), we characterized mutational signatures using 84,729,690 somatic mutations from 4,645 whole-genome and 19,184 exome sequences that encompass most types of cancer. We identified 49 single-base-substitution, 11 doublet-base-substitution, 4 clustered-base-substitution and 17 small insertion-and-deletion signatures. The substantial size of our dataset, compared with previous analyses 3–15 , enabled the discovery of new signatures, the separation of overlapping signatures and the decomposition of signatures into components that may represent associated—but distinct—DNA damage, repair and/or replication mechanisms. By estimating the contribution of each signature to the mutational catalogues of in idual cancer genomes, we revealed associations of signatures to exogenous or endogenous exposures, as well as to defective DNA-maintenance processes. However, many signatures are of unknown cause. This analysis provides a systematic perspective on the repertoire of mutational processes that contribute to the development of human cancer.
Peroxydisulfate activation by positively polarized carbocatalyst for enhanced removal of aqueous organic pollutants
Publisher: Elsevier BV
Date: 12-2019
DOI: 10.1016/J.WATRES.2019.115043
Abstract: Multi-walled carbon nanotubes (MWCNTs) eroxydisulfate (PDS) is a green oxidative system for abatement of aqueous organic pollutants, while the powder form and poor cycling performance of the catalyst limit its practical application. To solve these problems, fabricating a MWCNT cathode (negative polarization) to coupling carbocatalysis-driven PDS activation with electrosorption of organic pollutant was previously demonstrated to be a possible solution to these problems. To further improve the activation efficiency of PDS, positive polarization of MWCNT electrode (anode) was adapted to activate PDS for removing acyclovir and phenol in this work. Under a working voltage of 1.2 V, the MWCNT anode was more efficient than the MWCNT cathode and the non-polarized MWCNT electrode for PDS activation and removal of organic pollutants, owing to the enhanced attraction between S
Crystal transformation of 2D tungstic acid H2 WO4 to WO3 for enhanced photocatalytic water oxidation
Publisher: Elsevier BV
Date: 03-2018
DOI: 10.1016/J.JCIS.2017.12.066
Abstract: New photocatalytic materials for stable reduction and/or oxidization of water by harvesting a wider range of visible light are indispensable to achieve high practical efficiency in artificial photosynthesis. In this work, we prepared 2D WO
Inferring structural variant cancer cell fraction
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41467-020-14351-8
Abstract: We present SVclone, a computational method for inferring the cancer cell fraction of structural variant (SV) breakpoints from whole-genome sequencing data. SVclone accurately determines the variant allele frequencies of both SV breakends, then simultaneously estimates the cancer cell fraction and SV copy number. We assess performance using in silico mixtures of real s les, at known proportions, created from two clonal metastases from the same patient. We find that SVclone’s performance is comparable to single-nucleotide variant-based methods, despite having an order of magnitude fewer data points. As part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) consortium, which aggregated whole-genome sequencing data from 2658 cancers across 38 tumour types, we use SVclone to reveal a subset of liver, ovarian and pancreatic cancers with subclonally enriched copy-number neutral rearrangements that show decreased overall survival. SVclone enables improved characterisation of SV intra-tumour heterogeneity.
Directional Electron Transfer in Single-Atom Cobalt Nanozyme for Enhanced Photo-Fenton-Like Reaction
Publisher: Elsevier BV
Date: 2023
DOI: 10.2139/SSRN.4406047
Degradation of Microplastics by a Thermal Fenton Reaction
Publisher: American Chemical Society (ACS)
Date: 24-11-2022
Nanocarbons in different structural dimensions (0-3D) for phenol adsorption and metal-free catalytic oxidation
Publisher: Elsevier BV
Date: 12-2015
Unveiling the Origins of Selective Oxidation in Single-Atom Catalysis via Co–N4–C Intensified Radical and Nonradical Pathways
Publisher: American Chemical Society (ACS)
Date: 11-07-2022
Abstract: Single-atom catalysts (SACs)-based peroxymonosulfate (PMS) systems are highly selective to the type of organic pollutants while the mechanisms remain ambiguous. In this work, we carried out experimental and theoretical investigations to reveal the origins of selectivity of radical and nonradical pathways in a designated Co-N
Author Correction: Inferring structural variant cancer cell fraction
Publisher: Springer Science and Business Media LLC
Date: 23-08-2021
Single-atom catalysts on metal-based supports for solar photoreduction catalysis
Publisher: Elsevier BV
Date: 09-2022
Ultra-sustainable Fe 78 Si 9 B 13 metallic glass as a catalyst for activation of persulfate on methylene blue degradation under UV-Vis light
Publisher: Springer Science and Business Media LLC
Date: 06-12-2016
DOI: 10.1038/SREP38520
Abstract: Stability and reusability are important characteristics of advanced catalysts for wastewater treatment. In this work, for the first time, sulfate radicals (SO 4 ∙ − ) with a high oxidative potential (E o = 2.5–3.1 V) were successfully activated from persulfate by a Fe 78 Si 9 B 13 metallic glass. This alloy exhibited a superior surface stability and reusability while activating persulfate as indicated by it being used for 30 times while maintaining an acceptable methylene blue (MB) degradation rate. The produced SiO 2 layer on the ribbon surface expanded strongly from the fresh use to the 20 th use, providing stable protection of the buried Fe. MB degradation and kinetic study revealed 100% of the dye degradation with a kinetic rate k = 0.640 within 20 min under rational parameter control. The dominant reactive species for dye molecule decomposition in the first 10 min of the reaction was hydroxyl radicals (∙OH, E o = 2.7 V) and in the last 10 min was sulfate radicals (SO 4 ∙ − ), respectively. Empirical operating variables for dye degradation in this work were under catalyst dosage 0.5 g/L, light irradiation 7.7 μW/cm 2 , and persulfate concentration 1.0 mmol/L. The amorphous Fe 78 Si 9 B 13 alloy in this work will open a new gate for wastewater remediation.
Insights into Heterogeneous Catalysis of Persulfate Activation on Dimensional-Structured Nanocarbons
Publisher: American Chemical Society (ACS)
Date: 07-07-2015
Whole-genome landscape of pancreatic neuroendocrine tumours
Publisher: Springer Science and Business Media LLC
Date: 15-02-2017
DOI: 10.1038/NATURE21063
Abstract: The diagnosis of pancreatic neuroendocrine tumours (PanNETs) is increasing owing to more sensitive detection methods, and this increase is creating challenges for clinical management. We performed whole-genome sequencing of 102 primary PanNETs and defined the genomic events that characterize their pathogenesis. Here we describe the mutational signatures they harbour, including a deficiency in G:C > T:A base excision repair due to inactivation of MUTYH, which encodes a DNA glycosylase. Clinically sporadic PanNETs contain a larger-than-expected proportion of germline mutations, including previously unreported mutations in the DNA repair genes MUTYH, CHEK2 and BRCA2. Together with mutations in MEN1 and VHL, these mutations occur in 17% of patients. Somatic mutations, including point mutations and gene fusions, were commonly found in genes involved in four main pathways: chromatin remodelling, DNA damage repair, activation of mTOR signalling (including previously undescribed EWSR1 gene fusions), and telomere maintenance. In addition, our gene expression analyses identified a subgroup of tumours associated with hypoxia and HIF signalling.
Fe containing template derived atomic Fe-N-C to boost Fenton-like reaction and charge migration analysis on highly active Fe-N4sites
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1TA02446A
Abstract: Atomic Fe–N–C materials derived from pyridine deposition on Fe containing templates transfer electrons from C to Fe via C–N–Fe bonds to highly activate PMS to generate O 2 ˙ − for AOPs.
Author Correction: The evolutionary history of 2,658 cancers
Publisher: Springer Science and Business Media LLC
Date: 25-01-2023
Facile preparation of hydrophilic In2O3 nanospheres and rods with improved performances for photocatalytic degradation of PFOA
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D0EN01216E
Abstract: This study used metal–organic-framework (MOF) derived In 2 O 3 for the photocatalytic degradation of PFOA for the first time. MOF derived In 2 O 3 demonstrated significantly enhanced performance for PFOA decomposition compared to commercial In 2 O 3 .
S-scheme photocatalysis induced by ZnIn2S4 nanoribbons-anchored hierarchical CeO2 hollow spheres for boosted hydrogen evolution
Publisher: Elsevier BV
Date: 08-2022
DOI: 10.1016/J.JCIS.2022.04.024
Abstract: Developing S-scheme systems with impressive photocatalytic performance is of huge meaning in realizing the long-term conversion of solar energy into hydrogen. Herein, ZnIn
Unveiling the dual charge modulation of built-in electric field in metal-free photocatalysts for efficient photo-Fenton-like reaction
Publisher: Elsevier BV
Date: 02-2024
Novel polyoxometalateatg-C<inf>3</inf>N<inf>4</inf> hybrid photocatalysts for degradation of dyes and phenolics
Publisher: Elsevier BV
Date: 10-2015
DOI: 10.1016/J.JCIS.2015.06.003
Abstract: Graphitic carbon nitride (g-C3N4) is an emerging metal-free catalyst, and has attracted considerate research interests in photocatalysis. For improving the low photocatalytic activity due to the polymeric nature, a variety of methods have been developed. In this study, polyoxometalate (POMs) functionalized g-C3N4 were synthesized using a facile hydrothermal method as novel photocatalysts. The photocatalysts were characterized by field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), N2 sorption isotherms, thermogravimetric analysis (TGA), and UV-vis diffusion reflectance spectroscopy (UV-vis DRS). The photocatalytic properties were evaluated in photodecomposition of aqueous methylene blue (MB) and phenol under UV-visible light irradiations. Compared to pristine g-C3N4, POMs modified s les demonstrated enhanced efficiencies in photodegradation of MB and phenol. It was suggested that increased specific surface area, porous volume and efficient charge transfer would be responsible for the improved photocatalysis. This study proves the promising role of POMs in modification of novel photocatalysts.
Nickel in hierarchically structured nitrogen-doped graphene for robust and promoted degradation of antibiotics
Publisher: Elsevier BV
Date: 05-2019
Effects of nitrogen-, boron-, and phosphorus-doping or codoping on metal-free graphene catalysis
Publisher: Elsevier BV
Date: 07-2015
The Intrinsic Nature of Persulfate Activation and N-Doping in Carbocatalysis
Publisher: American Chemical Society (ACS)
Date: 17-04-2020
Nearly zero peroxydisulfate consumption for persistent aqueous organic pollutants degradation via nonradical processes supported by in-situ sulfate radical regeneration in defective MIL-88B(Fe)
Publisher: Elsevier BV
Date: 08-2023
Preparation of a p-n heterojunction BiFeO3@TiO2 photocatalyst with a core-shell structure for visible-light photocatalytic degradation
Publisher: Elsevier BV
Date: 06-2017
Catalytic membrane-based oxidation-filtration systems for organic wastewater purification: A review
Publisher: Elsevier BV
Date: 07-2021
Boron carbide boosted Fenton-like oxidation: A novel Fe(III)/Fe(II) circulation
Publisher: Elsevier BV
Date: 10-2020
Targeting mTOR dependency in pancreatic cancer
Publisher: BMJ
Date: 09-04-2014
Insights into the role of dual reaction sites for single Ni atom Fenton-like catalyst towards degradation of various organic contaminants
Publisher: Elsevier BV
Date: 05-2022
DOI: 10.1016/J.JHAZMAT.2022.128463
Abstract: The trade-off of Fenton-like catalysts in activity and stability remains a challenge in practical remediation applications. In this work, we successfully synthesized an efficient and stable catalyst comprised of single nickel (Ni) atoms dispersed on N-doped porous carbon (named Ni-SAs@CN) through a simple micropore confinement strategy. The catalyst exhibited outstanding catalytic performance with 25.8 min
Vanadium as co-catalyst for exceptionally boosted Fenton and Fenton-like oxidation: Vanadium species mediated direct and indirect routes
Publisher: Elsevier BV
Date: 03-2023
Magnetic Ni-Co alloy encapsulated N-doped carbon nanotubes for catalytic membrane degradation of emerging contaminants
Publisher: Elsevier BV
Date: 04-2019
A General Strategy to Synthesize Fluidic Single Atom Electrodes for Selective Reactive Oxygen Species Production
Publisher: American Chemical Society (ACS)
Date: 26-06-2023
Genomic footprints of activated telomere maintenance mechanisms in cancer
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41467-019-13824-9
Abstract: Cancers require telomere maintenance mechanisms for unlimited replicative potential. They achieve this through TERT activation or alternative telomere lengthening associated with ATRX or DAXX loss. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium , we dissect whole-genome sequencing data of over 2500 matched tumor-control s les from 36 different tumor types aggregated within the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium to characterize the genomic footprints of these mechanisms. While the telomere content of tumors with ATRX or DAXX mutations (ATRX/DAXX trunc ) is increased, tumors with TERT modifications show a moderate decrease of telomere content. One quarter of all tumor s les contain somatic integrations of telomeric sequences into non-telomeric DNA. This fraction is increased to 80% prevalence in ATRX/DAXX trunc tumors, which carry an aberrant telomere variant repeat (TVR) distribution as another genomic marker. The latter feature includes enrichment or depletion of the previously undescribed singleton TVRs TTCGGG and TTTGGG, respectively. Our systematic analysis provides new insight into the recurrent genomic alterations associated with telomere maintenance mechanisms in cancer.
Microplastics remediation in aqueous systems: Strategies and technologies
Publisher: Elsevier BV
Date: 06-2021
Quasi-MOF derivative-based electrode for efficient electro-Fenton oxidation
Publisher: Elsevier BV
Date: 2021
Accelerated sulfate radical generation from peroxymonosulfate by ZIF-67-derived Co3O4 encapsulated in g-C3N4: A gift from in situ growth
Publisher: Elsevier BV
Date: 03-2023
Boride-based electrocatalysts: Emerging candidates for water splitting
Publisher: Springer Science and Business Media LLC
Date: 02-01-2020
Surface Al and Co coordination for peroxymonosulfate activation: Identification and mechanism
Publisher: Elsevier BV
Date: 07-2023
A critical review on correlating active sites, oxidative species and degradation routes with persulfate-based antibiotics oxidation
Publisher: Elsevier BV
Date: 05-2023
Enhanced light-driven water splitting by fast electron transfer in 2D/2D reduced graphene oxide/tungsten trioxide heterojunction with preferential facets
Publisher: Elsevier BV
Date: 11-2019
DOI: 10.1016/J.JCIS.2019.08.008
Abstract: In this work, 2D/2D tungsten trioxide (WO
Metal-free catalytic ozonation on surface-engineered graphene: Microwave reduction and heteroatom doping
Publisher: Elsevier BV
Date: 2019
Kinetics and mechanism of synergistic adsorption and persulfate activation by N-doped porous carbon for antibiotics removals in single and binary solutions
Publisher: Elsevier BV
Date: 02-2022
DOI: 10.1016/J.JHAZMAT.2021.127083
Abstract: Porous carbon serves as a green material for efficient wastewater purification by adsorption and advanced oxidation processes. However, a clear understanding of the simultaneous removal of multiple pollutants in water is still ambiguous. Herein, the synergistic effect of adsorption and peroxydisulfate (PS) activation on kinetics and mechanism of removing single and binary antibiotic pollutants, sulfamethoxazole (SMX) and ibuprofen (IBP), from water by biomass-derived N-doped porous carbon was investigated. Our findings suggest that adsorption contributed to efficient removals of SMX/IBP. Comparative quenching experiments and electrochemical analysis demonstrated that hydroxyl (•OH) and sulfate (SO
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41467-019-13885-W
Abstract: The impact of somatic structural variants (SVs) on gene expression in cancer is largely unknown. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole-genome sequencing data and RNA sequencing from a common set of 1220 cancer cases, we report hundreds of genes for which the presence within 100 kb of an SV breakpoint associates with altered expression. For the majority of these genes, expression increases rather than decreases with corresponding breakpoint events. Up-regulated cancer-associated genes impacted by this phenomenon include TERT , MDM2 , CDK4 , ERBB2 , CD274 , PDCD1LG2 , and IGF2 . TERT -associated breakpoints involve ~3% of cases, most frequently in liver biliary, melanoma, sarcoma, stomach, and kidney cancers. SVs associated with up-regulation of PD1 and PDL1 genes involve ~1% of non- lified cases. For many genes, SVs are significantly associated with increased numbers or greater proximity of enhancer regulatory elements near the gene. DNA methylation near the promoter is often increased with nearby SV breakpoint, which may involve inactivation of repressor elements.
V2O5 nanodot-decorated laminar C3N4 for sustainable photodegradation of amoxicillin under solar light
Publisher: Elsevier BV
Date: 04-2022
Photocatalytic activation of peroxymonosulfate by surface-tailored carbon quantum dots
Publisher: Elsevier BV
Date: 08-2020
Catalytic degradation of antibiotics by metal-free catalysis over nitrogen-doped graphene
Publisher: Elsevier BV
Date: 11-2020
Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41467-020-14352-7
Abstract: The type and genomic context of cancer mutations depend on their causes. These causes have been characterized using signatures that represent mutation types that co-occur in the same tumours. However, it remains unclear how mutation processes change during cancer evolution due to the lack of reliable methods to reconstruct evolutionary trajectories of mutational signature activity. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole-genome sequencing data from 2658 cancers across 38 tumour types, we present TrackSig, a new method that reconstructs these trajectories using optimal, joint segmentation and deconvolution of mutation type and allele frequencies from a single tumour s le. In simulations, we find TrackSig has a 3–5% activity reconstruction error, and 12% false detection rate. It outperforms an aggressive baseline in situations with branching evolution, CNA gain, and neutral mutations. Applied to data from 2658 tumours and 38 cancer types, TrackSig permits pan-cancer insight into evolutionary changes in mutational processes.
Photothermal catalytic C1 conversion on supported catalysts
Publisher: Royal Society of Chemistry (RSC)
Date: 2023
DOI: 10.1039/D3YA00315A
Progress on Cu-based metal-organic frameworks for high-efficiency electrochemical CO2 conversion
Publisher: Elsevier BV
Date: 03-2023
Carbon dots based photocatalysis for environmental applications
Publisher: Elsevier BV
Date: 04-2022
Aerobic oxidation of 5-hydroxymethylfurfural into 2,5-diformylfuran using manganese dioxide with different crystal structures: A comparative study
Publisher: Elsevier BV
Date: 06-2021
All-solid-state Z-scheme heterostructures of 1T/2H-MoS2 nanosheets coupled V-doped hierarchical TiO2 spheres for enhanced photocatalytic activity
Publisher: Elsevier BV
Date: 2022
Roles of Catalyst Structure and Gas Surface Reaction in the Generation of Hydroxyl Radicals for Photocatalytic Oxidation
Publisher: American Chemical Society (ACS)
Date: 11-02-2022
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S42003-019-0741-7
Abstract: Long non-coding RNAs (lncRNAs) are a growing focus of cancer genomics studies, creating the need for a resource of lncRNAs with validated cancer roles. Furthermore, it remains debated whether mutated lncRNAs can drive tumorigenesis, and whether such functions could be conserved during evolution. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we introduce the Cancer LncRNA Census (CLC), a compilation of 122 GENCODE lncRNAs with causal roles in cancer phenotypes. In contrast to existing databases, CLC requires strong functional or genetic evidence. CLC genes are enriched amongst driver genes predicted from somatic mutations, and display characteristic genomic features. Strikingly, CLC genes are enriched for driver mutations from unbiased, genome-wide transposon-mutagenesis screens in mice. We identified 10 tumour-causing mutations in orthologues of 8 lncRNAs, including LINC-PINT and NEAT1 , but not MALAT1 . Thus CLC represents a dataset of high-confidence cancer lncRNAs. Mutagenesis maps are a novel means for identifying deeply-conserved roles of lncRNAs in tumorigenesis.
pH-dependent generation of radical and nonradical species for sulfamethoxazole degradation in different carbon/persulfate systems
Publisher: Elsevier BV
Date: 10-2022
DOI: 10.1016/J.WATRES.2022.119113
Abstract: The impacts of pH on purification efficiency can be phenomenal in advanced oxidation processes (AOPs), because solution pH affects persulfate (PS) activation processes. However, consensus has not been reached on the regimes of pH-regulated oxidation in persulfate-based AOPs (PS-AOPs). Particularly, the impacts of pH on carbon-catalyzed generation of radical and nonradical species remain unclear. In this work, we evaluated three typical carbonaceous materials including pyrolytic carbon (PC), activated carbon (AC), and carbon nanotube (CNT) to activate PS for sulfamethoxazole (SMX) degradation within a pH range from 4 to 9. The experiment revealed pH-dependent SMX removal in PC/PS, AC/PS, and CNT/PS, and the kinetics followed an order of pH 4 > pH 7 > pH 9. Solution pH simultaneously affected SMX adsorption and degradation, but the latter was more profound. Chemical quenching experiment, electrochemical measurement, kinetics calculation, and ATR-FTIR tests collectively revealed that high pH was not favorable for both radical and nonradical oxidation. In the PC/PS system, increased pH decreased the amount of phenolic -OH on PC surface, thereby restraining the generation of SO
Challenges in radical/nonradical-based advanced oxidation processes for carbon recycling
Publisher: Elsevier BV
Date: 08-2022
Catalytic transformation of microplastics to functional carbon for catalytic peroxymonosulfate activation: Conversion mechanism and defect of scavenging
Publisher: Elsevier BV
Date: 03-2024
Role of electronic properties in partition of radical and nonradical processes of carbocatalysis toward peroxymonosulfate activation
Publisher: Elsevier BV
Date: 11-2019
Author Correction: The repertoire of mutational signatures in human cancer
Publisher: Springer Science and Business Media LLC
Date: 25-01-2023
Synthesis of the 5–6–7 Tricyclic Core of Daphnicyclidin-Type Alkaloids via a Tiffeneau–Demjanov Ring Enlargement Strategy
Publisher: American Chemical Society (ACS)
Date: 06-10-2023
Insights into the oxidation of organic contaminants by iron nanoparticles encapsulated within boron and nitrogen co-doped carbon nanoshell: Catalyzed Fenton-like reaction at natural pH
Publisher: Elsevier BV
Date: 07-2019
DOI: 10.1016/J.ENVINT.2019.04.006
Abstract: Iron nanoparticles encapsulated within boron and nitrogen co-doped carbon nanoshell (B/N-C@Fe) were synthesized through a novel and green pyrolysis process using melamine, boric acid, and ferric nitrate as the precursors. The surface morphology, structure, and composition of the B/N-C@Fe materials were thoroughly investigated. The materials were employed as novel catalysts for the activation of potassium monopersulfate triple salt (PMS) for the degradation of levofloxacin (LFX). Linear sweep voltammograms and quenching experiments were used to identify the mechanisms of PMS activation and LFX oxidation by B/N-C@Fe, where SO
Single-atom coordination-dependent catalysis for peroxymonosulfate-mediated water purification
Publisher: Elsevier BV
Date: 09-2023
Intrinsic Mechanisms of Morphological Engineering and Carbon Doping for Improved Photocatalysis of 2D/2D Carbon Nitride Van Der Waals Heterojunction
Publisher: Wiley
Date: 13-05-2022
DOI: 10.1002/EEM2.12365
Abstract: Van der Waals (VDW) heterojunctions in a 2D/2D contact provide the highest area for the separation and transfer of charge carriers. In this work, a top‐down strategy with a gas erosion process was employed to fabricate a 2D/2D carbon nitride VDW heterojunction in carbon nitride (g‐C 3 N 4 ) with carbon‐rich carbon nitride. The created 2D semiconducting channel in the VDW structure exhibits enhanced electric field exposure and radiation absorption, which facilitates the separation of the charge carriers and their mobility. Consequently, compared with bulk g‐C 3 N 4 and its nanosheets, the photocatalytic performance of the fabricated carbon nitride VDW heterojunction in the water splitting reaction to hydrogen is improved by 8.6 and 3.3 times, respectively, while maintaining satisfactory photo‐stability. Mechanistically, the finite element method (FEM) was employed to evaluate and clarify the contributions of the formation of VDW heterojunction to enhanced photocatalysis, in agreement quantitatively with experimental ones. This study provides a new and effective strategy for the modification and more insights to performance improvement on polymeric semiconductors in photocatalysis and energy conversion.
Insights into the Electron-Transfer Regime of Peroxydisulfate Activation on Carbon Nanotubes: The Role of Oxygen Functional Groups
Publisher: American Chemical Society (ACS)
Date: 17-12-2020
Abstract: Carbon-driven advanced oxidation processes are appealing in wastewater purification because of the metal-free feature of the carbocatalysts. However, the regime of the emerging nonradical pathway is ambiguous because of the intricate carbon structure. To this end, this study was dedicated to unveil the intrinsic structure-performance relationship of peroxydisulfate (PDS) activation by carbon nanotubes (CNTs) toward nonradical oxidation of organics such as phenol (PE) via electron transfer. Eighteen analogical CNTs were synthesized and functionalized with different categories and contents of oxygen species. The quenching tests and chronopotentiometry suggest that an improved reactivity of surface-regulated CNTs was attributed to the reinforced electron-transfer regime without generation of free radicals and singlet oxygen. The quantitative structure-activity relationships were established and correlated to the Tafel equation, which unveils the nature of the nonradical oxidation by CNT-activated PDS complexes (CNT-PDS*). First, a decline in the concentration of oxygen groups in CNTs will make the zeta potential of the CNT become less negative in neutral solutions, which facilitated the adsorption of PDS because of weaker electrostatic repulsion. Then, the metastable CNT-PDS* was formed, which elevated the oxidation capacity of the CNT. Finally, PE would be oxidized over CNT-PDS* via electron transfer to fulfill the redox cycle. Moreover, the nonradical oxidation rate was uncovered to be exponentially related with the potential of the complexes, suggesting that the nonradical oxidation by the CNT-PDS* undergoes a mechanism analogous to anodic oxidation.
Long-lasting performance of high-flux perovskite membrane for catalytic degradation of organic pollutants
Publisher: Elsevier BV
Date: 06-2023
Photo-Induced Bismuth Single Atoms on TiO2 for Highly Efficient Photocatalytic Defluorination of Perfluorooctanoic Acid: Ionization of the C–F Bond
Publisher: American Chemical Society (ACS)
Date: 08-2023
Synergy of nitrogen doping and structural defects on hierarchically porous carbons toward catalytic oxidation via a non-radical pathway
Publisher: Elsevier BV
Date: 12-2019
Degradation of aniline by electrochemical activation of peroxydisulfate at MWCNT cathode: The proofed concept of nonradical oxidation process
Publisher: Elsevier BV
Date: 09-2018
DOI: 10.1016/J.CHEMOSPHERE.2018.04.173
Abstract: Enhanced elimination of aniline in aqueous solution was achieved by coupling electrosorption of aniline and electrochemical activation of peroxydisulfate (PDS) at multi-walled carbon nanotube (MWCNT) cathode, in which a synergistic effect occurred. It was found that PDS could be effectively activated under a small voltage at MWCNT cathode owing to the specific pore structures of MWCNTs. A nonradical oxidation pathway instead of radical-based oxidation was proposed from the cathodic activation of PDS, wherein PDS molecules with a modified electronic structure was suggested to be the principal reactive species. Meanwhile, the influences of various operation parameters such as electrode potential, PDS concentration, presence of chloride ions on the elimination efficiency, and the stability of MWCNT electrode were also attempted. Therefore, the electrochemical activation of PDS by MWCNT cathode is a promising energy-saving method for the treatment of organic pollutants in wastewater.
Active sites and reaction mechanism for N-doped carbocatalysis of phenol removal
Publisher: Elsevier BV
Date: 10-2020
Synthesis of magnetic carbon supported manganese catalysts for phenol oxidation by activation of peroxymonosulfate
Publisher: MDPI AG
Date: 26-12-2017
DOI: 10.3390/CATAL7010003
Degradation of Cosmetic Microplastics via Functionalized Carbon Nanosprings
Publisher: Elsevier BV
Date: 09-2019
Can we move towards personalised pancreatic cancer therapy?
Publisher: Informa UK Limited
Date: 04-04-2014
Construction of catalytic ozonation synergistic photo-self-Fenton system and analysis of synergistic catalysis and reaction mechanism activated by modified carbon nitride
Publisher: Elsevier BV
Date: 03-2024
Boosting elimination of sunscreen, Tetrahydroxybenzophenone (BP-2), from water using monopersulfate activated by thorny NanoBox of Co@C prepared via the engineered etching strategy: A comparative and mechanistic investigation
Publisher: Elsevier BV
Date: 06-2023
Electro-Fenton-Based Membrane System for Organic Micropollutant Removal: New Trend and Prospect
Publisher: American Chemical Society (ACS)
Date: 20-07-2023
Heterogeneous catalysis for environmental remediation
Publisher: MDPI AG
Date: 16-08-2017
DOI: 10.3390/CATAL7080236
Abstract: The intensive human activities in chemical industry and environmental purification urge the development of advanced protocols for green production and waste management. [...]
Revealing Intrinsic Relations Between Cu Scales and Radical/Nonradical Oxidations to Regulate Nucleophilic/Electrophilic Catalysis
Publisher: Wiley
Date: 05-01-2023
Abstract: Copper/carbon catalysts under different electron‐transfer regimes can evolve both radical and nonradical pathways in peroxide activation. However, the underlying trigger to manipulate the transition in between is unclear. Herein, it is revealed that Cu species in a state of sub‐nanometre particles (SNPs, 1 nm) exhibits an electrophilic nature, which is opposite to its nucleophilic nature at a larger scale (nanoclusters, 1 nm). This switch between nucleophile/electrophile nature leads to distinct catalytic mechanisms in activating peroxymonosulfate, i.e., nonradical 1 O 2 surface‐bound upon Cu SNPs and unleashed radical • OH induced by Cu nanoclusters. The vacancy defects of biomass‐derived carbon can stabilize Cu SNPs via a CuVC configuration, circumventing the contemporary difficulties in coordinating reserving MetalNC bonding. Depth profiling, chemical probes, and charge density difference modeling support the regulable electroactive nature over modulated Cu scales. This featured system is applied for tetracycline degradation, and Cu SNPs demonstrates the highest efficacy with their better peroxymonosulfate confinement in nonradical regime (88.9% removal, nucleophilic activation). Comparatively, severe Cu leaching caused by radical erosion (44.8% removal, electron‐donation) is undesirable. Overall, a regulable heterogeneous catalysis is unraveled over carbon‐supported Cu sites through scaling modulation and defect engineering. This study illuminates a promising path for customizing biomass‐derived Cu‐based catalysts to achieve versatile catalysis.
Comment on activation of Persulfate by Graphitized Nanodiamonds for Removal of Organic Compounds
Publisher: American Chemical Society (ACS)
Date: 14-04-2017
Nitrogen- and Sulfur-Codoped Hierarchically Porous Carbon for Adsorptive and Oxidative Removal of Pharmaceutical Contaminants
Publisher: American Chemical Society (ACS)
Date: 09-03-2016
Abstract: Heteroatom (nitrogen and sulfur)-codoped porous carbons (N-S-PCs) with high surface areas and hierarchically porous structures were successfully synthesized via direct pyrolysis of a mixture of glucose, sodium bicarbonate, and thiourea. The resulting N-S-PCs exhibit excellent adsorption abilities and are highly efficient for potassium persulfate activation when employed as catalysts for the oxidative degradation of sulfachloropyridazine (SCP) solutions. The adsorption capacities of N-S-PC-2 (which contains 4.51 atom % nitrogen and 0.22 atom % sulfur and exhibits SBET of 1608 m(2) g(-1)) are 73, 7, and 3 times higher than those of graphene oxide, reduced graphene oxide, and commercial single-walled carbon nanotube, respectively. For oxidation, the reaction rate constant of N-S-PC-2 is 0.28 min(-1). This approach not only contributes to the large-scale production and application of high-quality catalysts in water remediation but also provides an innovative strategy for the production of heteroatom-doped PCs for energy applications.
Flux-assisted synthesis of bismuth nanoparticle decorated carbon nitride for efficient photocatalytic degradation of endocrine disrupting compound
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2DT02900F
Abstract: Highly dispersed Bi would be served as cocatalysts to improve the separation of electron–hole carriers on the carbon nitride surface and provide more active sites for the photodegradation reaction of endocrine disrupting compound.
Efficient photocatalytic overall water splitting on metal-free 1D SWCNT/2D ultrathin C3N4 heterojunctions via novel non-resonant plasmonic effect
Publisher: Elsevier BV
Date: 12-2020
Carbon nitride-based Z-scheme photocatalysts for non-sacrificial overall water splitting
Publisher: Elsevier BV
Date: 2022
Nanostructured manganese oxides: natural/artificial formation and their induced catalysis for wastewater remediation
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/C9EN01250H
Abstract: Manganese oxides, with low toxicity and wide adaptability, have been demonstrated as promising catalysts for substituting noble metals/oxides in a ersity of chemical reactions.
Sustainable Catalytic Processes Driven by Graphene-Based Materials
Publisher: MDPI AG
Date: 05-06-2020
DOI: 10.3390/PR8060672
Abstract: In the recent two decades, graphene-based materials have achieved great successes in catalytic processes towards sustainable production of chemicals, fuels and protection of the environment. In graphene, the carbon atoms are packed into a well-defined sp2-hybridized honeycomb lattice, and can be further constructed into other dimensional allotropes such as fullerene, carbon nanotubes, and aerogels. Graphene-based materials possess appealing optical, thermal, and electronic properties, and the graphitic structure is resistant to extreme conditions. Therefore, the green nature and robust framework make the graphene-based materials highly favourable for chemical reactions. More importantly, the open structure of graphene affords a platform to host a ersity of functional groups, dopants, and structural defects, which have been demonstrated to play crucial roles in catalytic processes. In this perspective, we introduced the potential active sites of graphene in green catalysis and showcased the marriage of metal-free carbon materials in chemical synthesis, catalytic oxidation, and environmental remediation. Future research directions are also highlighted in mechanistic investigation and applications of graphene-based materials in other promising catalytic systems.
The National Aeronautics and Space Administration-task load index: NASA-TLX: evaluation of its use in surgery.
Publisher: Wiley
Date: 08-06-2022
DOI: 10.1111/ANS.17830
Abstract: The technical difficulty an operation creates for a surgeon is difficult to measure. Current measures are poor surrogates. In both research and teaching settings it would be valuable to be able to accurately measure this degree of difficulty. The National Aeronautics and Space Administration Task Load Index (NASA TLX) is a multi-dimensional scale designed to obtain workload estimates relating to a task. This study aimed to evaluate the NASA TLX as an objective measure of technical difficulty of an operation. Seven surgeons performed 127 pre-defined operations (minimally invasive right hemicolectomy & re-do bariatric surgery) and recorded a NASA TLX score after each operation. These scores were compared to numerous clinical parameters and the score was correlated with the subjective measure of whether the surgeon categorized the operation as "easy", "moderate" or "difficult". The NASA TLX score was significantly correlated with operative duration, blood loss, previous abdominal surgery and the surgeons' assessment of difficulty. It did not correlate with intra-operative or post-operative complications, conversion to open surgery or length of stay. The NASA TLX score provides a graded numerical score that that correlated significantly with the surgeon's assessment of the technical difficulty, and with operative duration, intra-operative blood loss and previous abdominal surgery. This novel application of this tool could be employed in both research and teaching settings to score surgical difficulty and monitor a trainee's proficiency over time.
Criteria of active sites in nonradical persulfate activation process from integrated experimental and theoretical investigations: boron–nitrogen-co-doped nanocarbon-mediated peroxydisulfate activation
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0EN00347F
Abstract: Reliable criteria for identifying the intrinsic active sites in carbocatalysts to mediate an electron-transfer mechanism in persulfate activation are presented.
Synergy of NiO quantum dots and temperature on enhanced photocatalytic and thermophoto hydrogen evolution
Publisher: Elsevier BV
Date: 06-2020
Directional and Ultrafast Charge Transfer in Oxygen-Vacancy-Rich ZnO@Single-Atom Cobalt Core-Shell Junction for Photo-Fenton-Like Reaction
Publisher: Wiley
Date: 20-06-2023
Abstract: In photosynthesis, solar energy is harvested by photosensitizers, and then, the excited electrons transfer via a Z‐Scheme mode to enzymatic catalytic centers to trigger redox reactions. Herein, we constructed a core–shell Z‐scheme heterojunction of semiconductor@single‐atom catalysts (SACs). The oxygen‐vacancy‐rich ZnO core and single‐atom Co−N 4 sites supported on nitrogen‐rich carbon shell (SA‐Co‐CN) act as the photosensitizer and the enzyme‐mimicking active centers, respectively. Driven by built‐in electric field across the heterojunction, photoexcited electrons could rapidly (2 ps) transfer from the n ‐type ZnO core to the p ‐type SA‐Co‐CN shell, finally boosting the catalytic performance of the surface‐exposed single‐atom Co−N 4 sites for peroxymonosulfate (PMS) activation under light irradiation. The synergies between photocatalysis and heterogeneous Fenton‐like reaction lead to phenomenally enhanced production of various reactive oxygen species for rapid degradation of various microcontaminants in water. Experimental and theoretical results validate that the interfacial coupling of SA‐Co‐CN with ZnO greatly facilitates PMS adsorption and activation by reducing the adsorption energy and enhancing the cascade electron transfer processes for the photo‐Fenton‐like reaction.
Hetero-interface-engineered sulfur vacancy and oxygen doping in hollow Co9S8/Fe7S8 nanospheres towards monopersulfate activation for boosting intrinsic electron transfer in paracetamol degradation
Publisher: Elsevier BV
Date: 08-2023
Mechanistic investigations of N-doped graphene/2H(1T)-MoS2 for Li/K-ions batteries
Publisher: Elsevier BV
Date: 12-2020
Selective production of singlet oxygen from zinc-etching hierarchically porous biochar for sulfamethoxazole degradation
Publisher: Elsevier BV
Date: 12-2021
Combined burden and functional impact tests for cancer driver discovery using DriverPower
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41467-019-13929-1
Abstract: The discovery of driver mutations is one of the key motivations for cancer genome sequencing. Here , as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium , which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we describe DriverPower, a software package that uses mutational burden and functional impact evidence to identify driver mutations in coding and non-coding sites within cancer whole genomes. Using a total of 1373 genomic features derived from public sources, DriverPower’s background mutation model explains up to 93% of the regional variance in the mutation rate across multiple tumour types. By incorporating functional impact scores, we are able to further increase the accuracy of driver discovery. Testing across a collection of 2583 cancer genomes from the PCAWG project, DriverPower identifies 217 coding and 95 non-coding driver candidates. Comparing to six published methods used by the PCAWG Drivers and Functional Interpretation Working Group, DriverPower has the highest F1 score for both coding and non-coding driver discovery. This demonstrates that DriverPower is an effective framework for computational driver discovery.
Simultaneous separation of multiphase emulsion mixture and catalytic degradation of BPA via microalgae residue membranes
Publisher: Elsevier BV
Date: 08-2020
Metal-Free Carbocatalysis in Advanced Oxidation Reactions
Publisher: American Chemical Society (ACS)
Date: 03-2018
DOI: 10.1021/ACS.ACCOUNTS.7B00535
Abstract: Catalytic processes have remarkably boosted the rapid industrializations in chemical production, energy conversion, and environmental remediation. As one of the emerging applications of carbocatalysis, metal-free nanocarbons have demonstrated promise as catalysts for green remediation technologies to overcome the poor stability and undesirable metal leaching in metal-based advanced oxidation processes (AOPs). Since our reports of heterogeneous activation of persulfates with low-dimensional nanocarbons, the novel oxidative system has raised tremendous interest for degradation of organic contaminants in wastewater without secondary contamination. In this Account, we showcase our recent contributions to metal-free catalysis in advanced oxidation, including design of nanocarbon catalysts, exploration of intrinsic active sites, and identification of reactive species and reaction pathways, and we offer perspectives on carbocatalysis for future environmental applications. The journey starts with the discovery of peroxymonosulfate (PMS) and peroxydisulfate (PDS) activation by graphene-based materials. With the systematic investigations on most carbon allotropes, for the first time the carbocatalysis for PMS or PDS activation was correlated with the pristine carbon configuration, oxygen functionality (ketonic groups), defect degree (exposed edge sites and vacancies), and dimensional structure. Moreover, an intrinsic difference in catalytic oxidation does exist between PMS and PDS activation. For ex le, the PMS/carbon reaction is dominated by free radicals, while PDS/carbon catalysis was unveiled as a singlet oxygen- or nonradical-based process in which the surface-activated PDS complex directly degrades the organic pollutants without relying on the generation of free radicals. Nitrogen doping significantly enhances the carbocatalysis because of the positively charged carbon domains, which strongly bind with persulfates to form reactive intermediates toward organic reactions. More importantly, N doping substantially alters the catalytic oxidation from a radical process to a nonradical pathway in PMS activation. Codoping of sulfur or boron with nitrogen at a rational level will synergistically promote the catalysis as a result of the formation of more catalytic centers by improved charge/spin redistribution of the carbon framework. Furthermore, a structure-performance relationship was established for annealed nanodiamonds with a characteristic sp
Oxygen Vacancies in Shape Controlled Cu2O/Reduced Graphene Oxide/In2O3 Hybrid for Promoted Photocatalytic Water Oxidation and Degradation of Environmental Pollutants
Publisher: American Chemical Society (ACS)
Date: 27-03-2017
Abstract: A novel shape controlled Cu
The evolutionary history of 2,658 cancers
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41586-019-1907-7
Abstract: Cancer develops through a process of somatic evolution 1,2 . Sequencing data from a single biopsy represent a snapshot of this process that can reveal the timing of specific genomic aberrations and the changing influence of mutational processes 3 . Here, by whole-genome sequencing analysis of 2,658 cancers as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA) 4 , we reconstruct the life history and evolution of mutational processes and driver mutation sequences of 38 types of cancer. Early oncogenesis is characterized by mutations in a constrained set of driver genes, and specific copy number gains, such as trisomy 7 in glioblastoma and isochromosome 17q in medulloblastoma. The mutational spectrum changes significantly throughout tumour evolution in 40% of s les. A nearly fourfold ersification of driver genes and increased genomic instability are features of later stages. Copy number alterations often occur in mitotic crises, and lead to simultaneous gains of chromosomal segments. Timing analyses suggest that driver mutations often precede diagnosis by many years, if not decades. Together, these results determine the evolutionary trajectories of cancer, and highlight opportunities for early cancer detection.
Activation of Peroxydisulfate on Carbon Nanotubes: Electron-Transfer Mechanism
Publisher: American Chemical Society (ACS)
Date: 13-11-2019
Abstract: This study proposed an electrochemical technique for investigating the mechanism of nonradical oxidation of organics with peroxydisulfate (PDS) activated by carbon nanotubes (CNT). The electrochemical property of twelve phenolic compounds (PCs) was evaluated by their half-wave potentials, which were then correlated to their kinetic rate constants in the PDS/CNT system. Integrated with quantitative structure-activity relationships (QSARs), electron paramagnetic resonance (EPR), and radical scavenging tests, the nature of nonradical pathways of phenolic compound oxidation was unveiled to be an electron-transfer regime other than a singlet oxygenation process. The QSARs were established according to their standard electrode potentials, activation energy, and pre-exponential factor. A facile electrochemical analysis method (chronopotentiometry combined with chrono erometry) was also employed to probe the mechanism, suggesting that PDS was catalyzed initially by CNT to form a CNT surface-confined and -activated PDS (CNT-PDS*) complex with a high redox potential. Then, the CNT-PDS* complex selectively abstracted electrons from the co-adsorbed PCs to initiate the oxidation. Finally, a comparison of PDS/CNT and graphite anodic oxidation under constant potentials was comprehensively analyzed to unveil the relative activity of the nonradical CNT-PDS* complex toward the oxidation of different PCs, which was found to be dependent on the oxidative potentials of the CNT-PDS* complex and the adsorbed organics.
Unraveling the phosphorus-nitrogen bridge in carbon quantum dots/carbon nitride for efficient photodegradation of organic contaminants
Publisher: Elsevier BV
Date: 02-2023
Sex differences in oncogenic mutational processes
Publisher: Springer Science and Business Media LLC
Date: 28-08-2020
DOI: 10.1038/S41467-020-17359-2
Abstract: Sex differences have been observed in multiple facets of cancer epidemiology, treatment and biology, and in most cancers outside the sex organs. Efforts to link these clinical differences to specific molecular features have focused on somatic mutations within the coding regions of the genome. Here we report a pan-cancer analysis of sex differences in whole genomes of 1983 tumours of 28 subtypes as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. We both confirm the results of exome studies, and also uncover previously undescribed sex differences. These include sex-biases in coding and non-coding cancer drivers, mutation prevalence and strikingly, in mutational signatures related to underlying mutational processes. These results underline the pervasiveness of molecular sex differences and strengthen the call for increased consideration of sex in molecular cancer research.
Morphology-dependent photocatalysis of graphitic carbon nitride for sustainable remediation of aqueous pollutants: A mini review
Publisher: Elsevier BV
Date: 06-2022
Templating agent-mediated Cobalt oxide encapsulated in Mesoporous silica as an efficient oxone activator for elimination of toxic anionic azo dye in water: Mechanistic and DFT-assisted investigations
Publisher: Elsevier BV
Date: 02-2023
Insights into N-doping in single-walled carbon nanotubes for enhanced activation of superoxides: A mechanistic study
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C5CC05101K
Abstract: Nitrogen-doped SWCNTs with enhanced carbocatalysis were investigated in the activation of superoxides by advanced oxidation and theoretical calculations.
ACS ES&T Water Presents the 2022 Excellence in Review Awards
Publisher: American Chemical Society (ACS)
Date: 08-09-2023
Molecular Engineering toward Pyrrolic N-Rich M-N4 (M = Cr, Mn, Fe, Co, Cu) Single-Atom Sites for Enhanced Heterogeneous Fenton-Like Reaction
Publisher: Wiley
Date: 14-01-2021
Recent advances in direct gas–solid-phase photocatalytic conversion of CO2 for porous photocatalysts under different CO2 atmospheres
Publisher: Elsevier BV
Date: 2023
Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
Publisher: Springer Science and Business Media LLC
Date: 08-12-2021
Efficient removal and recovery of Cd2+ from aqueous solutions by capacitive deionization (CDI) method using biochars
Publisher: Elsevier BV
Date: 06-2023
Effects of Gabexate Mesylate on the Gut Microbiota and Metabolomics in Rats with Sepsis
Publisher: Informa UK Limited
Date: 12-2022
DOI: 10.2147/JIR.S392060
Recent advances in transition metal-based electrocatalysts for alkaline hydrogen evolution
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9TA03220G
Abstract: Transition metal-based electrocatalysts for alkaline hydrogen evolution reaction.
Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
Publisher: Springer Science and Business Media LLC
Date: 25-01-2023
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
Publisher: Springer Science and Business Media LLC
Date: 21-09-2020
DOI: 10.1038/S41467-020-18151-Y
Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA s les, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological ergences between two reproducible somatic variant detection efforts.
Microplastic materials in the environment: Problem and strategical solutions
Publisher: Elsevier BV
Date: 02-2023
Occurrence of both hydroxyl radical and surface oxidation pathways in N-doped layered nanocarbons for aqueous catalytic ozonation
Publisher: Elsevier BV
Date: 10-2019
Tandem internal electric fields in intralayer/interlayer carbon nitride homojunction with a directed flow of photo-excited electrons for photocatalysis
Publisher: Elsevier BV
Date: 09-2023
Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer
Publisher: Elsevier BV
Date: 2021
Nanostructured Co-Mn containing perovskites for degradation of pollutants: Insight into the activity and stability
Publisher: Elsevier BV
Date: 05-2018
DOI: 10.1016/J.JHAZMAT.2018.01.054
Abstract: The efficient oxidative removal of persistent organic components in wastewater relies on low-cost heterogeneous catalysts that offer high catalytic activity, stability, and recyclability. Here, we designed a series of nanostructured Co-Mn containing perovskite catalysts, LaCo
Genomic basis for RNA alterations in cancer
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41586-020-1970-0
Abstract: Transcript alterations often result from somatic changes in cancer genomes 1 . Various forms of RNA alterations have been described in cancer, including overexpression 2 , altered splicing 3 and gene fusions 4 however, it is difficult to attribute these to underlying genomic changes owing to heterogeneity among patients and tumour types, and the relatively small cohorts of patients for whom s les have been analysed by both transcriptome and whole-genome sequencing. Here we present, to our knowledge, the most comprehensive catalogue of cancer-associated gene alterations to date, obtained by characterizing tumour transcriptomes from 1,188 donors of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA) 5 . Using matched whole-genome sequencing data, we associated several categories of RNA alterations with germline and somatic DNA alterations, and identified probable genetic mechanisms. Somatic copy-number alterations were the major drivers of variations in total gene and allele-specific expression. We identified 649 associations of somatic single-nucleotide variants with gene expression in cis , of which 68.4% involved associations with flanking non-coding regions of the gene. We found 1,900 splicing alterations associated with somatic mutations, including the formation of exons within introns in proximity to Alu elements. In addition, 82% of gene fusions were associated with structural variants, including 75 of a new class, termed ‘bridged’ fusions, in which a third genomic location bridges two genes. We observed transcriptomic alteration signatures that differ between cancer types and have associations with variations in DNA mutational signatures. This compendium of RNA alterations in the genomic context provides a rich resource for identifying genes and mechanisms that are functionally implicated in cancer.
Facile Synthesis of High-Performance Nitrogen-Doped Hierarchically Porous Carbon for Catalytic Oxidation
Publisher: American Chemical Society (ACS)
Date: 26-02-2020
Advanced oxidation processes for water disinfection: Features, mechanisms and prospects
Publisher: Elsevier BV
Date: 04-2021
Interfacial Electric Field Tuning Carbon-Catalyzed Persulfate Activation toward a Maneuverable Oxidation Pathway for Enhanced Removal of Bisphenol A
Publisher: American Chemical Society (ACS)
Date: 21-07-2023
High-performance porous graphene from synergetic nitrogen doping and physical activation for advanced nonradical oxidation
Publisher: Elsevier BV
Date: 2020
DOI: 10.1016/J.JHAZMAT.2019.121010
Abstract: Porous nitrogen-doped reduced graphene oxide (NRGO) is successfully synthesized from graphene oxide via the combination of CO
Whole genomes redefine the mutational landscape of pancreatic cancer
Publisher: Springer Science and Business Media LLC
Date: 25-02-2015
DOI: 10.1038/NATURE14169
Size-controlled nanoscale octahedral HKUST-1 as an enhanced catalyst for oxidative conversion of vanillic alcohol: The mediating effect of polyvinylpyrrolidone
Publisher: Elsevier BV
Date: 12-2021
Graphitic Carbon Nitride Microtubes for Efficient Photocatalytic Overall Water Splitting: The Morphology Derived Electrical Field Enhancement
Publisher: American Chemical Society (ACS)
Date: 02-09-2020
Mechanistic Investigations of the Pyridinic N–Co Structures in Co Embedded N-Doped Carbon Nanotubes for Catalytic Ozonation
Publisher: American Chemical Society (ACS)
Date: 10-2020
Emerging investigator series: enhancing the degradation of ciprofloxacin in water using Oxone activated by urchin-like cubic and hollow-structured cobalt@N-doped carbon prepared by etching-engineering
Publisher: Royal Society of Chemistry (RSC)
Date: 2023
DOI: 10.1039/D3EW00009E
Abstract: Enhancing the degradation of ciprofloxacin in water using Oxone activated by urchin-like cubic and hollow-structured cobalt@N-doped carbon.
Efficient removal of organic and bacterial pollutants by Ag-La 0.8 Ca 0.2 Fe 0.94 O 3-Δ perovskite via catalytic peroxymonosulfate activation
Publisher: Elsevier BV
Date: 08-2018
DOI: 10.1016/J.JHAZMAT.2018.05.044
Abstract: Removal of toxic organics and bacterial disinfection are important tasks in wastewater treatment. Most heavy metal-based catalysts for degradation of aqueous organic pollutants in heterogeneous Fenton-like processes suffer from the toxicity of leached metals. The present work reports environmentally benign systems for both degradation of organics and bacterial disinfection. Calcium substituted LaFeO
Enhanced CO2 Adsorption and Selectivity of CO2/N2 on Amino-MIL-53(Al) Synthesized by Polar Co-solvents
Publisher: American Chemical Society (ACS)
Date: 17-12-2018
Kinetics study of chloride-activated peracetic acid for purifying bisphenol A: Role of Cl2/HClO and carbon-centered radicals
Publisher: Elsevier BV
Date: 08-2023
Role of oxygen vacancies and Mn sites in hierarchical Mn2O3/LaMnO3-Δ perovskite composites for aqueous organic pollutants decontamination
Publisher: Elsevier BV
Date: 05-2019
Cobalt-based coordination polymer-derived hexagonal porous cobalt oxide nanoplate as an enhanced catalyst for hydrogen generation from hydrolysis of borohydride
Publisher: Elsevier BV
Date: 11-2020
FeOCl Nanoparticles Loaded onto Oxygen-Enriched Carbon Nanotubes and Nickel-Foam-Based Cathodes for the Electro-Fenton Degradation of Pollutants
Publisher: American Chemical Society (ACS)
Date: 24-06-2022
Atomically dispersed Cu-N3 on hollow spherical carbon nitride for acetaminophen degradation: Generation of 1O2 from H2O2
Publisher: Elsevier BV
Date: 08-2023
Catalytic Removal of Aqueous Contaminants on N-Doped Graphitic Biochars: Inherent Roles of Adsorption and Nonradical Mechanisms
Publisher: American Chemical Society (ACS)
Date: 20-07-2018
Coupling hydrothermal and photothermal single-atom catalysis toward excellent water splitting to hydrogen
Publisher: Elsevier BV
Date: 04-2021
Nitrogen-doped bamboo-like carbon nanotubes with Ni encapsulation for persulfate activation to remove emerging contaminants with excellent catalytic stability
Publisher: Elsevier BV
Date: 2018
Zn phthalocyanine/carbon nitride heterojunction for visible light photoelectrocatalytic conversion of CO2 to methanol
Publisher: Elsevier BV
Date: 03-2019
Selective formation of reactive oxygen species in peroxymonosulfate activation by metal-organic framework-derived membranes: A defect engineering-dependent study
Publisher: Elsevier BV
Date: 09-2022
Photothermal catalysis: From fundamentals to practical applications
Publisher: Elsevier BV
Date: 09-2023
Selective adsorption of rare earth ions from aqueous solution on metal-organic framework HKUST-1
Publisher: Elsevier BV
Date: 09-2020
Confinement boosted heterogeneous advanced oxidation processes
Publisher: Elsevier BV
Date: 09-2023
Engineered carbon supported single iron atom sites and iron clusters from Fe-rich Enteromorpha for Fenton-like reactions via nonradical pathways
Publisher: Elsevier BV
Date: 06-2021
Active sites decoration on sewage sludge-red mud complex biochar for persulfate activation to degrade sulfanilamide
Publisher: Elsevier BV
Date: 02-2022
DOI: 10.1016/J.JCIS.2021.10.150
Abstract: Active sites on catalyst surface play significant roles in oxidative species formation. The work focused on the regulation of main active sites on catalyst surface and oxidative species formation. Herein, sewage sludge (SS)-red mud (RM) complex biochar (SRCB) and N-functionalized SRCB (NSRCB) were served as activators of peroxymonosulfate (PMS) for sulfanilamide (SMX) degradation. Specially, NSRCB-1 showed excellent catalytic performance with 97.5% removal of SMX within 110 min. Additionally, the effects of N incorporation on the reconstruction of N species, conversion of intrinsic Fe species and ketonic CO groups in SRCB were studied systematically. Both radical (hydroxyl radicals (OH), sulfate radicals (SO
The duet of surface and radical-based carbocatalysis for oxidative destructions of aqueous contaminants over built-in nanotubes of graphite
Publisher: Elsevier BV
Date: 02-2020
DOI: 10.1016/J.JHAZMAT.2019.121486
Abstract: Metal-free mesoporous graphitic frameworks with built-in nanotubes (CPGs) were synthesized via facile co-pyrolysis of cyclodextrin and a cobalt salt with subsequent acid pickling to remove the embedded metal species. Due to the high graphitic degree and built-in few-layer nanotubes, the as-synthesized carbonaceous materials possess a higher catalytic ozonation activity than that of the state-of-the-art carbon nanotubes (CNTs) and LaMnO
Single-atom catalysis in advanced oxidation processes for environmental remediation
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D0CS01032D
Abstract: This review presents the recent advances in synthetic strategies, characterisation, and computations of carbon-based single-atom catalysts, as well as their innovative applications and mechanisms in advanced oxidation technologies.
Advances of piezoelectric nanomaterials for applications in advanced oxidation technologies
Publisher: Elsevier BV
Date: 09-2021
Tailored synthesis of active reduced graphene oxides from waste graphite: Structural defects and pollutant-dependent reactive radicals in aqueous organics decontamination
Publisher: Elsevier BV
Date: 08-2018
Mixed Conducting Perovskite Materials as Superior Catalysts for Fast Aqueous-Phase Advanced Oxidation: A Mechanistic Study
Publisher: American Chemical Society (ACS)
Date: 12-12-2017
Directional electron transfer in single-atom cobalt nanozyme for enhanced photo-Fenton-like reaction
Publisher: Elsevier BV
Date: 10-2023
Electron transfer to direct oxidation of aqueous organics by perovskites
Publisher: Springer Science and Business Media LLC
Date: 25-03-2023
Constructing direct Z-scheme heterojunctions of defective MoS2-v on carbon nitride nanotubes for high-performance hydrogen peroxide production and iron-free photo-Fenton-like reactions over a wide pH
Publisher: Elsevier BV
Date: 05-2023
Chemical activation of nitrogen and sulfur co-doped graphene as defect-rich carbocatalyst for electrochemical water splitting
Publisher: Elsevier BV
Date: 07-2019
Carbocatalytic ozonation toward advanced water purification
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1TA02953C
Abstract: This review summarizes the recent advances in carbocatalyzed ozonation and the corresponding surface engineering protocols and mechanistic insights.
Occurrence of radical and nonradical pathways from carbocatalysts for aqueous and nonaqueous catalytic oxidation
Publisher: Elsevier BV
Date: 07-2016
Sp2/sp3 Framework from Diamond Nanocrystals: A Key Bridge of Carbonaceous Structure to Carbocatalysis
Publisher: American Chemical Society (ACS)
Date: 12-07-2019
Accelerating radical generation from peroxymonosulfate by confined variable Co species toward ciprofloxacin mineralization: ROS quantification and mechanisms elucidation
Publisher: Elsevier BV
Date: 10-2022
Z-scheme plasmonic Ag decorated WO3/Bi2WO6 hybrids for enhanced photocatalytic abatement of chlorinated-VOCs under solar light irradiation
Publisher: Elsevier BV
Date: 03-2019
Activation of peroxymonosulfate by carbonaceous oxygen groups: Experimental and density functional theory calculations
Publisher: Elsevier BV
Date: 12-2016
Interfacial-engineered cobalt@carbon hybrids for synergistically boosted evolution of sulfate radicals toward green oxidation
Publisher: Elsevier BV
Date: 11-2019
Microencapsulated paraffin with SiO2 and Cu-BTC composite shell as shape-stabilized thermal energy storage materials
Publisher: Elsevier BV
Date: 07-2023
Interface-engineered hollow carbon matrix-supported FeCo alloy as an enhanced magnetic activator for peroxymonosulfate to degrade an endocrine disruptor in water: A comparative study for elucidating advantageous roles of Fe-dopant
Publisher: Elsevier BV
Date: 11-2023
Insights into nitrogen and boron-co-doped graphene toward high-performance peroxymonosulfate activation: Maneuverable N-B bonding configurations and oxidation pathways
Publisher: Elsevier BV
Date: 09-2019
Correlation of Active Sites to Generated Reactive Species and Degradation Routes of Organics in Peroxymonosulfate Activation by Co-Loaded Carbon
Publisher: American Chemical Society (ACS)
Date: 18-11-2021
Abstract: Peroxymonosulfate (PMS)-based advanced oxidation processes (PMS-AOPs) as an efficient strategy for organic degradation are highly dependent on catalyst design and structured active sites. However, the identification of the active sites and their relationship with reaction mechanisms for organic degradation are not fully understood for a composite catalyst due to the complex structure. Herein, we developed a family of Co encapsulated in N-doped carbons (Co-PCN) with tailored types and contents of active sites via manipulated pyrolysis for PMS activation and ciprofloxacin (CIP) degradation, focusing on the correlation of active sites to generated reactive species and degradation routes of organics. The structure-function relationships between the different active sites in Co-PCN catalysts and reactive oxygen species (ROS), as well as bond breaking position of CIP, were revealed through regression analysis and density functional theory calculation. Co-N
MIL-53(Fe) derived magnetic CuFe2O4/Fe2O3 composite for catalytic oxidation of sulfamethoxazole via peroxymonsulfate activation
Publisher: Elsevier BV
Date: 08-2023
Iridium-based nanomaterials for electrochemical water splitting
Publisher: Elsevier BV
Date: 12-2020
Edge-enriched laminar hexagonal (2H) MoSe2-anchored sulfur vacancies-rich ReS2 nanoflowers for boosted light-to-hydrogen conversion
Publisher: Elsevier BV
Date: 05-2023
Electrocatalysts for acidic oxygen evolution reaction: Achievements and perspectives
Publisher: Elsevier BV
Date: 12-2020
CeO2 nanocrystal-modified layered MoS2/g-C3N4 as 0D/2D ternary composite for visible-light photocatalytic hydrogen evolution: Interfacial consecutive multi-step electron transfer and enhanced H2O reactant adsorption
Publisher: Elsevier BV
Date: 12-2019
Thermal activation of persulfates for organic wastewater purification: Heating modes, mechanism and influencing factors
Publisher: Elsevier BV
Date: 12-2022
A hierarchical salt-rejection strategy for sustainable and high-efficiency solar-driven desalination
Publisher: Elsevier BV
Date: 09-2023
Co/N co-doped carbonized wood sponge with 3D porous framework for efficient peroxymonosulfate activation: Performance and internal mechanism
Publisher: Elsevier BV
Date: 2022
Persulfate Activation on Crystallographic Manganese Oxides: Mechanism of Singlet Oxygen Evolution for Nonradical Selective Degradation of Aqueous Contaminants
Publisher: American Chemical Society (ACS)
Date: 27-11-2019
Abstract: Minerals and transitional metal oxides of earth-abundant elements are desirable catalysts for in situ chemical oxidation in environmental remediation. However, catalytic activation of peroxydisulfate (PDS) by manganese oxides was barely investigated. In this study, one-dimension manganese dioxides (α- and β-MnO
Enhanced removals of micropollutants in binary organic systems by biomass derived porous carbon/peroxymonosulfate
Publisher: Elsevier BV
Date: 04-2021
Elucidation of the mechanistic origin of spin-state-dependent P-doped Fe single-atom catalysts for the oxidation of organic pollutants through peroxymonosulfate activation
Publisher: Elsevier BV
Date: 02-2024
Fast and Long-Lasting Iron(III) Reduction by Boron Toward Green and Accelerated Fenton Chemistry
Publisher: Wiley
Date: 13-08-2020
Highly interconnected sponge with optimized water absorption and thermal conductivity for efficient solar desalination
Publisher: Elsevier BV
Date: 06-2023
Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
Publisher: Springer Science and Business Media LLC
Date: 08-12-2022
Insights into boron accelerated Fenton-like chemistry: Sustainable and fast FeIII/FeII circulation
Publisher: Elsevier BV
Date: 07-2023
Confined FeNi alloy nanoparticles in carbon nanotubes for photothermal oxidative dehydrogenation of ethane by carbon dioxide
Publisher: Elsevier BV
Date: 12-2023
An insight into metal organic framework derived N-doped graphene for the oxidative degradation of persistent contaminants: formation mechanism and generation of singlet oxygen from peroxymonosulfate
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C6EN00633G
Abstract: Singlet oxygen produced during peroxymonosulfate activation by N-graphene dominated the pollutants degradation.
Visible-light-responsive Cl/S co-doped carbon nitride nanotubes for photocatalytic denitrification: A new reaction pathway dominated by photo-electrons
Publisher: Elsevier BV
Date: 05-2022
Synthesis of nitrogen and sulfur doped graphene on graphite foam for electro-catalytic phenol degradation and water splitting
Publisher: Elsevier BV
Date: 02-2021
Pretreatment of membrane dye wastewater by CoFe-LDH-activated peroxymonosulfate: Performance, degradation pathway, and mechanism
Publisher: Elsevier BV
Date: 02-2023
DOI: 10.1016/J.CHEMOSPHERE.2022.137346
Abstract: When a membrane is used to treat dye wastewater, dye molecules are continually concentrated at the membrane surface over time, resulting in a dramatic decrease in membrane flux. Aside from routine membrane cleaning, the pretreatment of dye wastewater to degrade organic pollutants into tiny molecules is a facile solution to the problem. In this study, the use of layered double hydroxide (LDH) to activate peroxymonosulfate (PMS) for efficient degradation of organic pollutant has been thoroughly investigated. We utilized a simple two-drop co-precipitation process to prepare CoFe-LDH. The transition metal components in CoFe-LDH effectively activate PMS to create oxidative free radicals, and the layered structure of LDH increases the number of active sites, and thereby considerably enhancing the reaction rate. It was found that the reaction process produced non-free and free radicals, including singlet oxygen (
Facile synthesis of nitrogen-doped graphene via low-temperature pyrolysis: The effects of precursors and annealing ambience on metal-free catalytic oxidation
Publisher: Elsevier BV
Date: 05-2017
Magnetic biochar catalysts from anaerobic digested sludge: Production, application and environment impact
Publisher: Elsevier BV
Date: 05-2019
DOI: 10.1016/J.ENVINT.2019.02.032
Abstract: Regulated disposal or re-utilization of dewatered sludge is of economic benefits and can avoid secondary contamination to the environment however, feasible and effective management strategies are still lacking. In this study, a peroxydisulfate/zero-valent iron (PDS-ZVI) system is proposed to destroy proteins in soluble extracellular polymeric substances (S-EPS) and loosely bound EPS (LB-EPS) in anaerobic digested sludge (ADS) to improve the dewaterability. Moreover, ADS derived biochars supported via iron oxides (Fe-ADSBC) were generated by dewatering and thermal annealing. Intriguingly, the iron species was discovered to gradually transform from Fe
Edge-Rich Bicrystalline 1T/2H-MoS2Cocatalyst-Decorated {110} Terminated CeO2Nanorods for Photocatalytic Hydrogen Evolution
Publisher: American Chemical Society (ACS)
Date: 26-07-2021
Ambient-Visible-Light-Mediated Enhanced Degradation of UV Stabilizer Bis(4-hydroxyphenyl)methanone by Nanosheet-Assembled Cobalt Titanium Oxide: A Comparative and DFT-Assisted Investigation
Publisher: MDPI AG
Date: 20-10-2022
DOI: 10.3390/W14203318
Abstract: Bis(4-hydroxyphenyl)methanone (BHPM), a common ultraviolet stabilizer and filter (USF), is extensively added in sunscreens however, BHPM is proven as an endocrine disruptor, posing a serious threat to aquatic ecology, and BHPM should be then removed. As sulfate radical (SO4•−) could be useful for eliminating emerging contaminants, oxone appears as a favorable source reagent of SO4•− for degrading BHPM. Even though cobalt is a useful catalyst for activating oxone to generate SO4•−, it would be even more promising to utilize ambient-visible-light irradiation to enhance oxone activation using cobaltic catalysts. Therefore, in contrast to the conventional cobalt oxide, cobalt titanium oxide (CTO) was investigated for chemical and photocatalytic activation of oxone to eliminate BHPM from water. Especially, a special morphology of nanosheet-assembled configuration of CTO was designed to maximize active surfaces and sites of CTO. Thus, CTO outperforms Co3O4 and TiO2 in degrading BHPM via oxone activation. Furthermore, the substituent of Ti enabled CTO to enhance absorption of visible light and possessed a much smaller Eg. These photocatalytic properties intensified CTO’s activity for oxone activation. CTO possessed a significantly smaller Ea of degradation of USFs than other catalytic systems. Mechanistic insight for degrading BHPM by CTO + oxone was explicated for identifying contribution of reactive oxygen species to BHPM degradation. The BHPM degradation pathway was also investigated and unveiled in details via the DFT calculation. These results validated that CTO is a superior cobaltic alternative for activating oxone to eliminate BHPM.
Photochemical degradation of phenol solutions on Co3O4 nanorods with sulfate radicals
Publisher: Elsevier BV
Date: 12-2015
Heterogeneous activation of peroxymonosulfate by amorphous boron for degradation of bisphenol S
Publisher: Elsevier BV
Date: 2017
DOI: 10.1016/J.JHAZMAT.2016.10.020
Abstract: Recently, tremendous efforts have been devoted to developing carbon-based metal-free catalysts as an alternative to metal-based catalysts for remediation of emerging contaminants. However, further investigations have demonstrated that the durability of carbocatalysts is poor. Therefore, it is extremely desirable to seek a novel metal-free catalyst with high efficiency and superb stability. Herein, we first discovered that amorphous boron (A-boron) can be used as a metal-free catalyst for peroxymonosulfate (PMS) activation to produce free radicals for effective degradation of bisphenol S (BPS), which is a newly-occurring estrogenic endocrine-disrupting chemical. It exhibited outstanding catalytic activity and superior stability as comparing to metal-based and metal-free carbon-based catalysts. Moreover, many other typical organic pollutants in water such as bisphenol F, sulfamethoxazole, rhodamine B and methyl orange can also be effectively decomposed in A-boron/PMS oxidative system. The effects of reaction parameters on BPS degradation were systematically investigated. The catalytic oxidation mechanism was proposed. The intriguing catalytic feature of A-boron discovered in this study will provide new opportunities for the future development of A-boron based materials with promising applications in water remediation.
Potential Difference Driving Electron Transfer via Defective Carbon Nanotubes toward Selective Oxidation of Organic Micropollutants
Publisher: American Chemical Society (ACS)
Date: 10-06-2020
Surface controlled generation of reactive radicals from persulfate by carbocatalysis on nanodiamonds
Publisher: Elsevier BV
Date: 10-2016
Nano-sized FeVO4·1.1H2O and FeVO4 for peroxymonosulfate activation towards enhanced photocatalytic activity
Publisher: Elsevier BV
Date: 04-2022
Pan-cancer analysis of whole genomes
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41586-020-1969-6
Abstract: Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale 1–3 . Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4–5 driver mutations when combining coding and non-coding genomic elements however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution in acral melanoma, for ex le, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter 4 identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation 5,6 analyses timings and patterns of tumour evolution 7 describes the erse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity 8,9 and evaluates a range of more-specialized features of cancer genomes 8,10–18 .
Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes
Publisher: Springer Science and Business Media LLC
Date: 08-12-2022
Adjunctive sepsis therapy with aminophylline (STAP): a randomized controlled trial
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 05-12-2022
N-doping-induced nonradical reaction on single-walled carbon nanotubes for catalytic phenol oxidation
Publisher: American Chemical Society (ACS)
Date: 22-12-2015
DOI: 10.1021/CS5017613
DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association
Publisher: Springer Science and Business Media LLC
Date: 03-02-2021
DOI: 10.1038/S42003-020-01469-0
Abstract: Here we report the DNA methylation profile of 84 sporadic pancreatic neuroendocrine tumors (PanNETs) with associated clinical and genomic information. We identified three subgroups of PanNETs, termed T1, T2 and T3, with distinct patterns of methylation. The T1 subgroup was enriched for functional tumors and ATRX , DAXX and MEN1 wild-type genotypes. The T2 subgroup contained tumors with mutations in ATRX , DAXX and MEN1 and recurrent patterns of chromosomal losses in half of the genome with no association between regions with recurrent loss and methylation levels. T2 tumors were larger and had lower methylation in the MGMT gene body, which showed positive correlation with gene expression. The T3 subgroup harboured mutations in MEN1 with recurrent loss of chromosome 11, was enriched for grade G1 tumors and showed histological parameters associated with better prognosis. Our results suggest a role for methylation in both driving tumorigenesis and potentially stratifying prognosis in PanNETs.
Three-dimensional nitrogen-doped graphene oxide beads for catalytic degradation of aqueous pollutants
Publisher: Elsevier BV
Date: 10-2022
Nonradical oxidation in persulfate activation by graphene-like nanosheets (GNS): Differentiating the contributions of singlet oxygen (1O2) and sorption-dependent electron transfer
Publisher: Elsevier BV
Date: 08-2020
N-Doped Graphene from Metal–Organic Frameworks for Catalytic Oxidation of p-Hydroxylbenzoic Acid: N-Functionality and Mechanism
Publisher: American Chemical Society (ACS)
Date: 20-02-2017
Rational design of Spirulina residue-derived graphene oxide as an efficient metal-free catalyst for sulfathiazole removal
Publisher: Elsevier BV
Date: 06-2022
Facilely achieved enhancement of Fenton-like reactions by constructing electric microfields
Publisher: Elsevier BV
Date: 03-2023
Carbocatalytic activation of persulfate for removal of antibiotics in water solutions
Publisher: Elsevier BV
Date: 03-2016
Carbon nitride-based Z-scheme heterojunctions for solar-driven advanced oxidation processes
Publisher: Elsevier BV
Date: 07-2022
DOI: 10.1016/J.JHAZMAT.2022.128866
Abstract: Solar-driven advanced oxidation processes (AOPs) via direct photodegradation or indirect photocatalytic activation of typical oxidants, such as hydrogen peroxide (H
Enzyme-mimicking single-atom FeN4 sites for enhanced photo-Fenton-like reactions
Publisher: Elsevier BV
Date: 08-2022
Disordered Atomic Packing Structure of Metallic Glass: Toward Ultrafast Hydroxyl Radicals Production Rate and Strong Electron Transfer Ability in Catalytic Performance
Publisher: Wiley
Date: 02-08-2017
Activation of peroxymonosulfate by natural pyrite for efficient degradation of V(IV)-citrate complex in groundwater
Publisher: Elsevier BV
Date: 07-2022
DOI: 10.1016/J.JCIS.2022.03.057
Abstract: The V(IV)-organic complexes are difficult to be removed from water by the traditional water treatment processes due to their strong mobility, high stability, and possible formation of V(V) with stronger toxicity during oxidation. In this study, we applied a natural iron-based ore, pyrite, to catalyze peroxymonosulfate (PMS) activation assisted with alkali precipitation to remove V(IV) containing complexes. The effects of initial V(IV)-citrate concentration, PMS concentration, ore dosage and natural anions were comprehensively investigated using citric acid as a model ligand. Results showed that pyrite can effectively purify V(IV)-citrate. Specifically, 99.4 ± 0.4% of total vanadium and 73.6 ± 0.9% of total organic carbon are removed, and the pyrite maintained high catalytic activity after multiple uses. Characterization analyses revealed that free metal ions including Fe and V(IV) ions in the solution were removed by subsequent alkali precipitation. Radical quenching experiments indicated that sulfate radical (SO
Catalytic oxidation of sulfachloropyridazine by MnO2: Effects of crystalline phase and peroxide oxidants
Publisher: Elsevier BV
Date: 03-2021
Remediation of antibiotic wastewater by coupled photocatalytic and persulfate oxidation system: A critical review
Publisher: Elsevier BV
Date: 04-2021
Pathway and network analysis of more than 2500 whole cancer genomes
Publisher: Springer Science and Business Media LLC
Date: 05-02-2020
DOI: 10.1038/S41467-020-14367-0
Abstract: The catalog of cancer driver mutations in protein-coding genes has greatly expanded in the past decade. However, non-coding cancer driver mutations are less well-characterized and only a handful of recurrent non-coding mutations, most notably TERT promoter mutations, have been reported. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancer across 38 tumor types, we perform multi-faceted pathway and network analyses of non-coding mutations across 2583 whole cancer genomes from 27 tumor types compiled by the ICGC/TCGA PCAWG project that was motivated by the success of pathway and network analyses in prioritizing rare mutations in protein-coding genes. While few non-coding genomic elements are recurrently mutated in this cohort, we identify 93 genes harboring non-coding mutations that cluster into several modules of interacting proteins. Among these are promoter mutations associated with reduced mRNA expression in TP53 , TLE4 , and TCF4 . We find that biological processes had variable proportions of coding and non-coding mutations, with chromatin remodeling and proliferation pathways altered primarily by coding mutations, while developmental pathways, including Wnt and Notch, altered by both coding and non-coding mutations. RNA splicing is primarily altered by non-coding mutations in this cohort, and s les containing non-coding mutations in well-known RNA splicing factors exhibit similar gene expression signatures as s les with coding mutations in these genes. These analyses contribute a new repertoire of possible cancer genes and mechanisms that are altered by non-coding mutations and offer insights into additional cancer vulnerabilities that can be investigated for potential therapeutic treatments.
Density Functional Theory Calculations for Insight into the Heterocatalyst Reactivity and Mechanism in Persulfate-Based Advanced Oxidation Reactions
Publisher: American Chemical Society (ACS)
Date: 23-08-2021
Origins of Electron-Transfer Regime in Persulfate-Based Nonradical Oxidation Processes
Publisher: American Chemical Society (ACS)
Date: 21-12-2021
Abstract: Persulfate-based nonradical oxidation processes (PS-NOPs) are appealing in wastewater purification due to their high efficiency and selectivity for removing trace organic contaminants in complicated water matrices. In this review, we showcased the recent progresses of state-of-the-art strategies in the nonradical electron-transfer regimes in PS-NOPs, including design of metal and metal-free heterogeneous catalysts, in situ/operando characterization/analytical techniques, and insights into the origins of electron-transfer mechanisms. In a typical electron-transfer process (ETP), persulfate is activated by a catalyst to form surface activated complexes, which directly or indirectly interact with target pollutants to finalize the oxidation. We discussed different analytical techniques on the fundamentals and tactics for accurate analysis of ETP. Moreover, we demonstrated the challenges and proposed future research strategies for ETP-based systems, such as computation-enabled molecular-level investigations, rational design of catalysts, and real-scenario applications in the complicated water environment. Overall, this review dedicates to sharpening the understanding of ETP in PS-NOPs and presenting promising applications in remediation technology and green chemistry.
MOF-templated hollow cobalt sulfide as an enhanced Oxone activator for degradation of UV Absorber: Key role of sulfur Vacancy-Induced highly active CoII sites
Publisher: Elsevier BV
Date: 02-2023
Sludge-derived biochar toward sustainable Peroxymonosulfate Activation: Regulation of active sites and synergistic production of reaction oxygen species
Publisher: Elsevier BV
Date: 07-2022
A purified membrane protein from Akkermansia muciniphila blunted the sepsis-induced acute lung injury by modulation of gut microbiota in rats
Publisher: Elsevier BV
Date: 08-2023
Formation of Fe(IV) over a wide pH range via iron-carbon composite-catalyzed persulfate activation
Publisher: Elsevier BV
Date: 04-2023
Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
Publisher: Springer Science and Business Media LLC
Date: 08-12-2022
Unzipping MWCNTs for controlled edge- and heteroatom-defects in revealing their roles in gas-phase oxidative dehydrogenation of ethanol to acetaldehyde
Publisher: Elsevier BV
Date: 10-2022
Single atom catalysts for heterogeneous catalytic ozonation
Publisher: Elsevier BV
Date: 09-2023
Confined Tri-Functional FeOx@MnO2@SiO2 Flask Micromotors for Long-Lasting Motion and Catalytic Reactions
Publisher: Wiley
Date: 26-01-2023
Abstract: H 2 O 2 ‐fueled micromotors are state‐of‐the‐art mobile microreactors in environmental remediation. In this work, a magnetic FeO x @MnO 2 @SiO 2 micromotor with multi‐functions is designed and demonstrated its catalytic performance in H 2 O 2 eroxymonosulfate (PMS) activation for simultaneously sustained motion and organic degradation. Moreover, this work reveals the correlations between catalytic efficiency and motion behavior/mechanism. The inner magnetic FeO x nanoellipsoids primarily trigger radical species ( • OH and O 2 •− ) to attack organics via Fenton‐like reactions. The coated MnO 2 layers on FeO x surface are responsible for decomposing H 2 O 2 into O 2 bubbles to provide a propelling torque in the solution and generating SO 4 •− and • OH for organic degradation. The outer SiO 2 microcapsules with a hollow head and tail result in an asymmetrical Janus structure for the motion, driven by O 2 bubbles ejecting from the inner cavity via the opening tail. Intriguingly, PMS adjusts the local environment to control over‐violent O 2 formation from H 2 O 2 decomposition by occupying the Mn sites via inter‐sphere interactions and enhances organic removal due to the strengthened contacts and Fenton‐like reactions between inner FeO x and peroxides within the microreactor. The findings will advance the design of functional micromotors and the knowledge of micromotor‐based remediation with controlled motion and high‐efficiency oxidation using multiple peroxides.
N-doped graphitic biochars from C-phycocyanin extracted Spirulina residue for catalytic persulfate activation toward nonradical disinfection and organic oxidation
Publisher: Elsevier BV
Date: 08-2019
DOI: 10.1016/J.WATRES.2019.05.008
Abstract: Biochars are low-cost and environmental-friendly materials, which are promising in wastewater treatment. In this study, biochars were manufactured from C-phycocyanin extracted (C-CP) Spirulina residue (SDBC) via thermal pyrolysis. Simultaneously, N-doping was also achieved from the protein in the algae for obtaining a high-performance carbocatalyst for peroxydisulfate (PDS) activation. The SDBC yielded large specific surface areas, nitrogen loading, and good conductivity, which demonstrated excellent oxidation efficiencies toward a wide array of aqueous microcontaminants. An in-depth mechanistic study was performed by integrating selective radical scavenging, solvent exchange (H
Amino-functionalized NH2-MIL-125(Ti)-decorated hierarchical flowerlike Znln2S4 for boosted visible-light photocatalytic degradation
Publisher: Elsevier BV
Date: 03-2022
DOI: 10.1016/J.ENVRES.2021.112368
Abstract: Developing novel heterojunction photocatalysts with visible-light response and remarkable photocatalytic activity have been verified to applying for the photodegradation of antibiotics in water environment. Herein, NH
Single-atom catalysts derived from biomass: low-cost and high-performance persulfate activators for water decontamination
Publisher: Elsevier BV
Date: 09-2023
New insight to piezocatalytic peroxymonosulfate activation: The critical role of dissolved oxygen in mediating radical and nonradical pathways
Publisher: Elsevier BV
Date: 10-2022
Engineered tourmaline/g-C3N4 composites for photocatalytic Fenton-like oxidation: Synergy of spontaneous interface polarization and surface iron circulations induced by minerals
Publisher: Elsevier BV
Date: 03-2023
Bismuth-based complex oxides for photocatalytic applications in environmental remediation and water splitting: A review
Publisher: Elsevier BV
Date: 2022
Catalytic carbon and hydrogen cycles in plastics chemistry
Publisher: Elsevier BV
Date: 04-2022
Fine‐Tuning Surface Properties of Perovskites via Nanocompositing with Inert Oxide toward Developing Superior Catalysts for Advanced Oxidation
Publisher: Wiley
Date: 21-09-2018
Modulation of Charge Trapping by Island-like Single-Atom Cobalt Catalyst for Enhanced Photo-Fenton-Like reaction
Publisher: Wiley
Date: 06-01-2023
Abstract: Composites‐based photocatalysis relies on the interfacial electron transfer between the metallic cocatalyst and photosensitizer (the semiconductor) to realize spatial separation of charge carriers. Herein, an ingenious heterojunction between Co‐CN single atom catalysts (SACs) and g‐C 3 N 4 is constructed for heterogeneous photo‐Fenton‐like reactions. Driven by built‐in electric field across the heterojunctions, the separation and migration of the photogenerated charge carriers is promoted, leading to the fast electron transfer from the g‐C 3 N 4 to the Co‐CN SACs. Theoretical calculations and transient absorption spectroscopy reveal the modulated charge transfer and trapping in the SA‐Co‐CN/g‐C 3 N 4 heterostructure, resulting in the remarkably enhanced generation of reactive oxygen species via peroxymonosulfate activation under light irradiation. This ingenious SA‐Co‐CN/g‐C 3 N 4 /PMS/vis system is efficient for the oxidation of various antibiotics with high removal efficiency ( %), a wide operating pH range (pH 3–11) and excellent stability in long‐term operation. This study provides a new tactic for rational design of SACs‐based heterojunctions to bridge photocatalysis and heterogeneous catalysis, attaining superior photoredox activity via interfacial coupling.
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
Publisher: Springer Science and Business Media LLC
Date: 12-08-2019
DOI: 10.1038/S41467-019-10968-6
Abstract: Heterogeneous subtypes of cancer-associated fibroblasts (CAFs) coexist within pancreatic cancer tissues and can both promote and restrain disease progression. Here, we interrogate how cancer cells harboring distinct alterations in p53 manipulate CAFs. We reveal the existence of a p53-driven hierarchy, where cancer cells with a gain-of-function (GOF) mutant p53 educate a dominant population of CAFs that establish a pro-metastatic environment for GOF and null p53 cancer cells alike. We also demonstrate that CAFs educated by null p53 cancer cells may be reprogrammed by either GOF mutant p53 cells or their CAFs. We identify perlecan as a key component of this pro-metastatic environment. Using intravital imaging, we observe that these dominant CAFs delay cancer cell response to chemotherapy. Lastly, we reveal that depleting perlecan in the stroma combined with chemotherapy prolongs mouse survival, supporting it as a potential target for anti-stromal therapies in pancreatic cancer.
Synergy of carbocatalytic and heat activation of persulfate for evolution of reactive radicals toward metal-free oxidation
Publisher: Elsevier BV
Date: 09-2020
A new magnetic nano zero-valent iron encapsulated in carbon spheres for oxidative degradation of phenol
Publisher: Elsevier BV
Date: 08-2015
Self-assembly of 3D MnO 2 /N-doped graphene hybrid aerogel for catalytic degradation of water pollutants: Structure-dependent activity
Publisher: Elsevier BV
Date: 08-2019
Adsorption of cerium (III) by HKUST-1 metal-organic framework from aqueous solution
Publisher: Elsevier BV
Date: 04-2019
DOI: 10.1016/J.JCIS.2019.01.117
Abstract: Cerium is an important rare earth element (REE), which can be used for many high-tech applications. From the industrial and environmental viewpoints, it is imperative to recover Ce
Production, properties, and catalytic applications of sludge derived biochar for environmental remediation
Publisher: Elsevier BV
Date: 12-2020
Related Organisations
China University Of Petroleum (East China) - Qingdao Campus
Location: China
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