ORCID Profile
0000-0001-6279-0552
Current Organisations
National Institute of Pharmaceutical Education and Research Raebareli
,
Las Cumbres Observatory
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: American Astronomical Society
Date: 11-02-2019
Publisher: American Astronomical Society
Date: 28-12-2017
Publisher: American Astronomical Society
Date: 23-05-2016
Publisher: American Astronomical Society
Date: 26-10-2016
Publisher: American Astronomical Society
Date: 18-08-2017
Publisher: American Astronomical Society
Date: 07-2022
Abstract: We report the first unambiguous detection and mass measurement of an isolated stellar-mass black hole (BH). We used the Hubble Space Telescope (HST) to carry out precise astrometry of the source star of the long-duration ( t E ≃ 270 days), high-magnification microlensing event MOA-2011-BLG-191/OGLE-2011-BLG-0462 (hereafter designated as MOA-11-191/OGLE-11-462), in the direction of the Galactic bulge. HST imaging, conducted at eight epochs over an interval of 6 yr, reveals a clear relativistic astrometric deflection of the background star’s apparent position. Ground-based photometry of MOA-11-191/OGLE-11-462 shows a parallactic signature of the effect of Earth’s motion on the microlensing light curve. Combining the HST astrometry with the ground-based light curve and the derived parallax, we obtain a lens mass of 7.1 ± 1.3 M ⊙ and a distance of 1.58 ± 0.18 kpc. We show that the lens emits no detectable light, which, along with having a mass higher than is possible for a white dwarf or neutron star, confirms its BH nature. Our analysis also provides an absolute proper motion for the BH. The proper motion is offset from the mean motion of Galactic disk stars at similar distances by an amount corresponding to a transverse space velocity of ∼45 km s −1 , suggesting that the BH received a “natal kick” from its supernova explosion. Previous mass determinations for stellar-mass BHs have come from radial velocity measurements of Galactic X-ray binaries and from gravitational radiation emitted by merging BHs in binary systems in external galaxies. Our mass measurement is the first for an isolated stellar-mass BH using any technique.
Publisher: American Astronomical Society
Date: 11-2019
Publisher: American Astronomical Society
Date: 27-12-2020
Publisher: American Astronomical Society
Date: 20-10-2016
Publisher: American Astronomical Society
Date: 28-06-2016
Publisher: American Astronomical Society
Date: 07-11-2016
Publisher: American Astronomical Society
Date: 23-07-2020
Publisher: American Astronomical Society
Date: 16-10-2015
Publisher: IOP Publishing
Date: 07-2023
Abstract: The Vera C. Rubin Observatory will undertake the Legacy Survey of Space and Time, providing an unprecedented, volume-limited catalog of star clusters in the Southern Sky, including Galactic and extragalactic star clusters. The Star Clusters subgroup of the Stars, Milky Way and Local Volume Working Group has identified key areas where Rubin Observatory will enable significant progress in star cluster research. This roadmap represents our science cases and preparation for studies of all kinds of star clusters from the Milky Way out to distances of tens of megaparsecs.
Publisher: American Astronomical Society
Date: 09-06-2017
Publisher: MDPI AG
Date: 16-03-2022
DOI: 10.3390/PH15030360
Abstract: 1,2,4-trioxane is a pharmacophore, which possesses a wide spectrum of biological activities, including anticancer effects. In this study, the cytotoxic effect and anticancer mechanism of action of a set of 10 selected peroxides were investigated on five phenotypically different cancer cell lines (A549, A2780, HCT8, MCF7, and SGC7901) and their corresponding drug-resistant cancer cell lines. Among all peroxides, only 7 and 8 showed a better P-glycoprotein (P-gp) inhibitory effect at a concentration of 100 nM. These in vitro results were further validated by in silico docking and molecular dynamic (MD) studies, where compounds 7 and 8 exhibited docking scores of −7.089 and −8.196 kcal/mol, respectively, and remained generally stable in 100 ns during MD simulation. Further experiments revealed that peroxides 7 and 8 showed no significant effect on ROS accumulations and caspase-3 activity in A549 cells. Peroxides 7 and 8 were also found to decrease cell membrane potential. In addition, peroxides 7 and 8 were demonstrated to oxidize a flavin cofactor, possibly elucidating its mechanism of action. In conclusion, apoptosis induced by 1,2,4-trioxane was shown to undergo via a ROS- and caspase-3-independent pathway with hyperpolarization of cell membrane potential.
Publisher: Elsevier BV
Date: 09-2023
Publisher: American Astronomical Society
Date: 24-03-2023
Abstract: We analyze the MOA-2020-BLG-208 gravitational microlensing event and present the discovery and characterization of a new planet, MOA-2020-BLG-208Lb, with an estimated sub-Saturn mass. With a mass ratio q = 3.17 − 0.26 + 0.28 × 10 − 4 , the planet lies near the peak of the mass-ratio function derived by the MOA collaboration and near the edge of expected s le sensitivity. For these estimates we provide results using two mass-law priors: one assuming that all stars have an equal planet-hosting probability, and the other assuming that planets are more likely to orbit around more massive stars. In the first scenario, we estimate that the lens system is likely to be a planet of mass m planet = 46 − 24 + 42 M ⊕ and a host star of mass M host = 0.43 − 0.23 + 0.39 M ⊙ , located at a distance D L = 7.49 − 1.13 + 0.99 kpc . For the second scenario, we estimate m planet = 69 − 34 + 37 M ⊕ , M host = 0.66 − 0.32 + 0.35 M ⊙ , and D L = 7.81 − 0.93 + 0.93 kpc . The planet has a projected separation as a fraction of the Einstein ring radius s = 1.3807 − 0.0018 + 0.0018 . As a cool sub-Saturn-mass planet, this planet adds to a growing collection of evidence for revised planetary formation models.
Publisher: American Astronomical Society
Date: 02-08-2022
Abstract: We report on the observations, analysis and interpretation of the microlensing event MOA-2019-BLG-008. The observed anomaly in the photometric light curve is best described through a binary lens model. In this model, the source did not cross caustics and no finite-source effects were observed. Therefore, the angular Einstein ring radius θ E cannot be measured from the light curve alone. However, the large event duration, t E ∼ 80 days, allows a precise measurement of the microlensing parallax π E . In addition to the constraints on the angular radius θ * and the apparent brightness I s of the source, we employ the Besançon and GalMod galactic models to estimate the physical properties of the lens. We find excellent agreement between the predictions of the two galactic models: the companion is likely a resident of the brown dwarf desert with a mass M p ∼ 30 M Jup , and the host is a main-sequence dwarf star. The lens lies along the line of sight to the Galactic bulge, at a distance of ≤4 kpc. We estimate that in about 10 yr the lens and source will be separated by ∼55 mas, and it will be possible to confirm the exact nature of the lensing system by using high-resolution imaging from ground- or space-based observatories.
Publisher: American Astronomical Society
Date: 22-12-2021
Abstract: Vera C. Rubin Observatory is a ground-based astronomical facility under construction, a joint project of the National Science Foundation and the U.S. Department of Energy, designed to conduct a multipurpose 10 yr optical survey of the Southern Hemisphere sky: the Legacy Survey of Space and Time. Significant flexibility in survey strategy remains within the constraints imposed by the core science goals of probing dark energy and dark matter, cataloging the solar system, exploring the transient optical sky, and mapping the Milky Way. The survey’s massive data throughput will be transformational for many other astrophysics domains and Rubin’s data access policy sets the stage for a huge community of potential users. To ensure that the survey science potential is maximized while serving as broad a community as possible, Rubin Observatory has involved the scientific community at large in the process of setting and refining the details of the observing strategy. The motivation, history, and decision-making process of this strategy optimization are detailed in this paper, giving context to the science-driven proposals and recommendations for the survey strategy included in this Focus Issue.
Location: India
Location: India
Location: United States of America
Location: Japan
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United States of America
No related grants have been discovered for Rachel Street.