ORCID Profile
0000-0002-8886-8482
Current Organisation
University of the Free State
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Publisher: Elsevier BV
Date: 12-2020
Publisher: Elsevier BV
Date: 02-2021
Publisher: Elsevier BV
Date: 11-2020
Publisher: Future Science Ltd
Date: 03-2021
Abstract: The COVID-19 pandemic continues to endanger world health and the economy. The causative SARS-CoV-2 coronavirus has a unique replication system. The end point of the COVID-19 pandemic is either herd immunity or widespread availability of an effective vaccine. Multiple candidate vaccines – peptide, virus-like particle, viral vectors (replicating and nonreplicating), nucleic acids (DNA or RNA), live attenuated virus, recombinant designed proteins and inactivated virus – are presently under various stages of expansion, and a small number of vaccine candidates have progressed into clinical phases. At the time of writing, three major pharmaceutical companies, namely Pfizer and Moderna, have their vaccines under mass production and administered to the public. This review aims to investigate the most critical vaccines developed for COVID-19 to date.
Publisher: Elsevier BV
Date: 11-2020
Publisher: Springer Science and Business Media LLC
Date: 19-01-2022
Publisher: Elsevier BV
Date: 09-2020
Publisher: Elsevier BV
Date: 07-2021
Publisher: Tsinghua University Press
Date: 22-04-2022
Publisher: Mary Ann Liebert Inc
Date: 02-05-2021
DOI: 10.1089/ADT.2021.012
Publisher: Hindawi Limited
Date: 29-11-2020
DOI: 10.1111/JFBC.13572
Publisher: Informa UK Limited
Date: 29-06-2023
Publisher: Wiley
Date: 29-06-2023
DOI: 10.1002/CTD2.218
Abstract: Exosome is nanosized tiny membrane‐bound vesicles and is a subpopulation of extracellular vesicles (EVs). In general, it participates in intercellular communication and acts as a messenger of several pathological complications. Exosome and cancer interlink is the most exciting domain of current cancer research. The internal molecular cargos (proteins, lipids, metabolites, miRNA, and DNA) of tumor derived exosomes (TEXs) are capable of transforming normal cells into tumor phenotypes. Exosome DNA is the less explored area of EVs research. It is involved in several events in cancer progression such as uncontrol cell growth, reprogramming of immune cells, metastasis, and therapeutic resistance. Exo‐DNA is also involved in epigenetic alteration, which promotes cancer. It has a great impact on cancer theranostics (biomarker and therapeutics) research. Exo‐DNA‐based cancer examination supports more detailed cancer research.
Publisher: Elsevier BV
Date: 05-2021
No related grants have been discovered for Anand Krishnan.