ORCID Profile
0000-0003-4343-2738
Current Organisation
Umm Al-Qura University
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: International Journal of Pharma and Bio Sciences
Date: 07-2023
DOI: 10.22376/IJLPR.2023.13.4.L158-L166
Abstract: Globally, the WHO estimated 241 million malaria cases with 627000 deaths in Africa in 2020. Studying inversions in the X-chromosomes could detect behavioral changes and efficiency of transmission of Malaria in Anopheles phronesis species. These changes may lead to shifting from becoming a major vector of Malaria after the inability to transmit Malaria. The knowledge of the malaria transmission pattern of Anopheles pharoensis in Sudan needs to be improved. We aimed to detect the presence of any inversions or mutations in Anopheles pharoensis species collected from Egypt and Sudan and to undergo a Polymerase Chain Reaction (PCR) technique to detect mutations or X-chromosome inversions in the Sudanese and Egyptian strains of Anopheles pharoensis also to compare between the X-chromosome of the two species. It is an experimental, analytical study that aimed to detect inversions in the X –chromosomes of Anopheles phronesis collected from Egypt (Faiyoum Governate) and Sudan (Khartoum, Gezira, and Sennar states) of Sudanese Mosquito species. From the gel electrophoresis and PCR assay, inversions were detected by the 100Bp PCR products using primers. Only very few revealed bands from 75 Egyptian strains were detected by bands. The study revealed that Anopheles pharoensis species collected from Egypt have X- chromosome inversions. Inversions were absent in the Sudanese strains. The study also reacted to the fact that Anopheles phronesis could be a sibling species or a species complex, but further studies are needed to prove this. From the results and observations of this investigation, it was recommended to undergo further genetic studies on Anopheles species in Sudan and use of PCR technique in the classification.
Publisher: Springer Science and Business Media LLC
Date: 09-07-2021
DOI: 10.1007/S10653-020-00653-9
Abstract: DNA strand breaks are a common form of DNA damage that can contribute to chromosomal instability or gene mutations. Such strand breaks may be caused by exposure to heavy metals. The aim of this study was to assess the level of DNA strand breaks caused by µm-scale solid particles of known chemical composition with elevated heavy metals/metalloids, notably arsenic, using an in vitro cell-free DNA plasmid scission assay. These s les were incubated with and without H 2 O 2 to see whether damage occurs directly or indirectly through the Fenton reaction. Levels of DNA damage in the absence of H 2 O 2 were 10%, but in the presence of H 2 O 2 , all s les showed higher levels of damage ranging from 10 to 100% suggesting that damage was being incurred through the Fenton reaction. Using bivariate correlation analysis and multiple linear regression, manganese oxide (MnO), sulphur (S), copper (Cu), and zinc (Zn) concentrations in the particulates were found to be the most significant predictors of DNA damage. The mechanism of this DNA damage formation has yet to be thoroughly investigated but is hypothesised to be due to reactive oxygen species formation. Further work is required to assess the extent of contribution of reactive oxygen species to this DNA damage, but this study highlights the potential role of chemistry and/or mineralogy to the extent and/or nature of DNA damage caused by particulates.
Publisher: Public Library of Science (PLoS)
Date: 26-01-2023
DOI: 10.1371/JOURNAL.PONE.0280681
Abstract: The use of smartphones among the general public and health care practitioners, in particular, is ubiquitous. The aim of this study was to investigate the relationship between smartphone addiction and sleep quality, psychological distress, and loneliness among health care students and workers in Saudi Arabia. This cross-sectional study used an online questionnaire to collect data on smartphone addiction, sleep quality, psychological distress, and loneliness as well as demographic information. A total of 773 health care students and workers participated in the study, with an average age of 25.95 ± 8.35, and 59.6% female participants. The study found a positive significant association between smartphone addiction and psychological distress (F (1,771) = 140.8, P 0.001) and emotional loneliness (F (1,771) = 26.70, P 0.001). Additionally, a significant negative association between smartphone addiction and sleep quality was found (F (1,771) = 4.208, P = 0.041). However, there was no significant relationship between smartphone addiction and social loneliness (F (1,771) = 0.544, P 0.461). These findings suggest that smartphone addiction has a negative impact on psychological distress, sleep quality, and emotional loneliness among health care students and workers. It is important to promote strategies to reduce smartphone dependency in order to avoid the harmful consequences of smartphone addiction.
Publisher: Polaris
Date: 2023
DOI: 10.51847/TWWFP3C6S4
Publisher: Journal of Liaquat University of Medical and Health Sciences (JLUMHS)
Date: 09-10-2023
Publisher: Springer Science and Business Media LLC
Date: 28-08-2023
DOI: 10.7759/CUREUS.44234
Publisher: Polaris
Date: 2023
DOI: 10.51847/V7W6UQEKYE
Publisher: Springer Science and Business Media LLC
Date: 28-02-2022
Publisher: HARD Publishing Company
Date: 20-06-2022
Publisher: Medknow
Date: 2023
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Hatim Badri.