ORCID Profile
0000-0002-9818-4543
Current Organisations
University of Technology Sydney
,
Australian National University
,
University of Sydney
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International Business | Business and Management | Organisation and Management Theory
Publisher: Springer Science and Business Media LLC
Date: 17-04-2014
DOI: 10.1057/JIBS.2014.14
Publisher: Wiley
Date: 25-12-2021
DOI: 10.1002/SMJ.3262
Abstract: Strategy research views firms' erse experience base as critical to new product success. It also ch ions strategy‐by‐doing in entrepreneurial settings. This study juxtaposes and bridges these two perspectives to better understand product development. We propose that while a firm's product portfolio ersity contributes to new product success only to a certain degree, design iteration—a postlaunch strategy‐by‐doing approach—is positively associated with new product performance. Our core contribution points to a complementary relationship: strategy‐by‐doing helps mitigate the capacity constraints problem that prevents firms from successfully adapting product development capabilities to a dynamic market. Our analysis of a s le of 2,182 nascent mobile apps from 564 top producers in the U.S. market supports our hypotheses. We discuss implications for product development, strategy‐by‐doing, and technology innovation literature. Successful product development establishes firms' competitive advantage. The burgeoning digital economy increasingly prompts product development to depend on strategy‐by‐doing and requires firms to adapt a product's design over its lifecycle. Through analyzing a s le of newly launched mobile apps in the U.S. market, we find that while a firm's product portfolio ersity improves new product success to a certain degree, design iteration, a distinct approach to strategy‐by‐doing, underpins a new product's continual attractiveness to users. Moreover, frequent design iterations can overcome the barriers that innovator firms face when applying a erse repertoire of experiences to product development.
Publisher: Academy of Management
Date: 2015
Publisher: Springer Science and Business Media LLC
Date: 04-09-2015
Publisher: Emerald Group Publishing Limited
Date: 11-11-2014
Publisher: Elsevier BV
Date: 05-2018
Publisher: Elsevier BV
Date: 06-2019
Publisher: Oxford University Press
Date: 08-08-2018
DOI: 10.1093/OXFORDHB/9780190683948.013.27
Abstract: This chapter aims to take stock of existing research on emerging economy multinationals (EMNEs) in advanced host economies, a phenomenon often referred to as “South-North investment.” Both the extent of such investments and the stage in the firms’ internationalization life cycle in which these occur challenge some of the tenets of the traditional theories of multinational enterprises. The chapter critically evaluates the literature on this phenomenon and identifies three research themes related to the strategic motivation behind the investments, institutional influences, and network-based resources that explain EMNEs’ aggressive forays in advanced economies. Collectively, these theoretical and empirical studies contribute to a rethinking and refinement of current traditional understanding of the pace and paths of firm internationalization. The chapter further suggests that the unique strategic asset-seeking orientation behind EMNEs investments in advanced markets and the institutional support facilitating such expansion create important strategic and organizational challenges for these firms in their globalization efforts. Accordingly, the chapter identifies some research possibilities around related themes of ambidexterity, comparative institutionalism, and legitimacy that may facilitate further theorization and a better understanding of both normative and policy implications of the increasing investments of EMNEs in more developed economic and institutional environments.
Publisher: MDPI AG
Date: 20-12-2021
Abstract: High-fat diet (HFD)-induced comorbid cognitive and behavioural impairments are thought to be the result of persistent low-grade neuroinflammation. Metformin, a first-line medication for the treatment of type-2 diabetes, seems to ameliorate these comorbidities, but the underlying mechanism(s) are not clear. Pituitary adenylate cyclase-activating peptide (PACAP) and vasoactive intestinal peptide (VIP) are neuroprotective peptides endowed with anti-inflammatory properties. Alterations to the PACAP/VIP system could be pivotal during the development of HFD-induced neuroinflammation. To unveil the pathogenic mechanisms underlying HFD-induced neuroinflammation and assess metformin’s therapeutic activities, (1) we determined if HFD-induced proinflammatory activity was present in vulnerable brain regions associated with the development of comorbid behaviors, (2) investigated if the PACAP/VIP system is altered by HFD, and (3) assessed if metformin rescues such diet-induced neurochemical alterations. C57BL/6J male mice were ided into two groups to receive either standard chow (SC) or HFD for 16 weeks. A further HFD group received metformin (HFD + M) (300 mg/kg BW daily for 5 weeks) via oral gavage. Body weight, fasting glucose, and insulin levels were measured. After 16 weeks, the proinflammatory profile, glial activation markers, and changes within the PI3K/AKT intracellular pathway and the PACAP/VIP system were evaluated by real-time qPCR and/or Western blot in the hypothalamus, hippoc us, prefrontal cortex, and amygdala. Our data showed that HFD causes widespread low-grade neuroinflammation and gliosis, with regional-specific differences across brain regions. HFD also diminished phospho-AKT(Ser473) expression and caused significant disruptions to the PACAP/VIP system. Treatment with metformin attenuated these neuroinflammatory signatures and reversed PI3K/AKT and PACAP/VIP alterations caused by HFD. Altogether, our findings demonstrate that metformin treatment rescues HFD-induced neuroinflammation in vulnerable brain regions, most likely by a mechanism involving the reinstatement of PACAP/VIP system homeostasis. Data also suggests that the PI3K/AKT pathway, at least in part, mediates some of metformin’s beneficial effects.
Publisher: MDPI AG
Date: 31-08-2021
DOI: 10.20944/PREPRINTS202108.0559.V1
Abstract: Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are two structurally-related immunosuppressive peptides. However, the underlying mechanisms through which these peptides regulate microglial activity are not fully understood. Using lipopolysaccharide (LPS) to induce an inflammatory challenge, we tested whether PACAP or VIP differentially affected microglial activation, morphology and cell migration. We found that both peptides attenuated LPS-induced expression of the microglial activation markers Iba1 and iNOS (###p& .001), as well as the pro-inflammatory mediators IL-1& beta , IL-6, Itgam and CD68 (###p& .001). In contrast, treatment with PACAP or VIP exerted distinct effects on microglial morphology and migration. PACAP reversed LPS-induced soma enlargement and increased the percentage of small-sized, rounded cells (54.09% vs 12.05% in LPS-treated cells), whereas VIP promoted a phenotypic shift towards cell subpopulations with mid-sized, spindle-shaped soma (48.41% vs 31.36% in LPS-treated). Additionally, PACAP was more efficient than VIP in restoring LPS-induced impairment of cell migration and the expression of urokinase plasminogen activator (uPA) in BV2 cells compared with VIP. These results suggest that whilst both PACAP and VIP exert similar immunosuppressive effects in activated BV2 microglia, each peptide triggers distinctive shifts towards phenotypes of differing morphologies and with differing migration capacities.
Publisher: Emerald
Date: 16-11-2012
DOI: 10.1108/15253831211286264
Abstract: While many studies on institutional environment have primarily focused on the influence of the host country environment, limited insights have been offered on how the different dimensions of home institutions affect firm internationalization. This paper aims to fill this gap by investigating the effects of regulatory institutions at home. Using country governance quality to proxy quality of regulatory institutions, this study attempts to reveal how regulatory institutions at home facilitate a multinational enterprise's (MNE's) international expansion and why the influence differs in different country clusters. Using hierarchical linear modeling and cluster analysis, proposed hypotheses were tested with a three‐year panel of 511 firms from 38 countries. The results provide substantial support for the authors' hypotheses that MNEs with high governance quality at home are more engaged in internationalization than those with low governance quality at home. Moreover, differences in institutional effect do exist between country clusters. This study provides evidence that while country differences exist, governance quality at home can facilitate MNEs' expansion into foreign markets. This finding will help managers of any MNEs to consider country‐level factors and evaluate the governance quality at home before committing resources into foreign operations. Building on the institutional environment literature, this theory and results make original contributions by underscoring how the consideration of regulatory institutions at home can significantly improve understanding of institutional influence on MNEs. The findings have important implications for both international business researchers and managers of MNEs.
Publisher: Elsevier BV
Date: 02-2021
Publisher: Elsevier BV
Date: 12-2019
Publisher: Elsevier BV
Date: 02-2023
Publisher: Springer Science and Business Media LLC
Date: 05-03-2010
Publisher: Springer Science and Business Media LLC
Date: 29-06-0006
Publisher: Cambridge University Press (CUP)
Date: 20-06-2022
DOI: 10.1017/MOR.2022.10
Abstract: Ahsan, Sinha, and Srinivasan (2020) studied the motives of knowledge-intensive Indian firms’ international expansion based on resource-based considerations and the locational advantages offered by host countries. They identified firm characteristics associated with strategic asset-seeking, opportunity-seeking, and market-seeking motives. In this replication study, we examine Ahsan et al.'s (2020) model in the Chinese context. Based on our improved empirical model, our findings reveal some similarities but more importantly some key differences in the antecedents of internationalization motives between Indian and Chinese firms. Drawing on insights from prior studies, we propose that these differences can be attributed to differences in absorptive capacity, international expansion scales and patterns, ownership type, and the home institutional contexts in which Indian and Chinese firms operate. Overall, this replication study demonstrates the importance of contextualizing international business research.
Publisher: Elsevier BV
Date: 12-2021
Publisher: Informa UK Limited
Date: 24-07-2020
Publisher: Elsevier BV
Date: 04-2021
Publisher: Elsevier BV
Date: 06-2019
Publisher: Elsevier BV
Date: 09-2022
Publisher: Wiley
Date: 23-06-2011
DOI: 10.1002/TIE.20425
Publisher: Elsevier BV
Date: 06-2017
Publisher: Elsevier BV
Date: 12-2013
Publisher: SAGE Publications
Date: 30-08-2020
Abstract: This study explores how multinational enterprises (MNEs) take advantage of their ownership-based political capital – political ties and political identity – in responding to institutional voids in host country contexts. Investigating multiple cases of central and local Chinese state-owned enterprises in Africa, we identify unique responding strategies comprising allied fleet and co-dependent alliance formations to overcome human capital voids, and dual management and closed-door management strategies to address industry standard voids. We propose a typology which extends the theory of MNE responses to institutional voids not only by adding the political dimension to strategy formation in responding to institutional voids, but also by providing greater insights into MNE strategies to convert home-based political capital for better response to host country institutional voids.
Publisher: Elsevier BV
Date: 09-2018
Publisher: MDPI AG
Date: 25-03-2018
DOI: 10.3390/IJMS19040981
Publisher: Wiley
Date: 18-10-2023
DOI: 10.1111/JOMS.13009
Publisher: MDPI AG
Date: 25-05-2021
Abstract: Buspirone is an anxiolytic drug with robust serotonin receptor 1A (Htr1a) agonist activities. However, evidence has demonstrated that this drug also targets the dopamine D3 receptor (Drd3), where it acts as a potent antagonist. In vivo, Drd3 blockade is neuroprotective and reduces inflammation in models of Parkinson’s disease. To test if buspirone also elicited anti-inflammatory activities in vitro, we generated stable Drd3−/− and Htr1a−/− BV2 microglial cell lines using CRISPR-Cas9 technology and then tested the effects of buspirone after lipopolysaccharide (LPS) challenge. We found that LPS exposure had no effect on cell viability, except in Htr1a−/− cells, where viability was reduced (p 0.001). Drug treatment reduced viability in Drd3−/− cells, but not in WT or Htr1a−/− cells. Buspirone counteracted LPS-induced NO release, NOS2, IL-1β and TNF-α gene expression in WT cells, whereas it exerted limited effects in Drd3−/− or Htr1a−/− microglia. In summary, our findings indicate that buspirone attenuates microglial polarization after LPS challenge. These results also highlight some major effects of Drd3 or Htr1a genetic ablation on microglial biology, raising important questions on the complex role of neurotransmitters in regulating microglia functions.
Publisher: Wiley
Date: 10-02-2017
DOI: 10.1002/GSJ.1153
Publisher: Wiley
Date: 24-07-2018
DOI: 10.1002/GSJ.1325
Publisher: Cambridge University Press (CUP)
Date: 21-09-2021
DOI: 10.1017/MOR.2021.53
Abstract: This study examines the international performance of emerging economy multinational enterprises (EMNEs) from a strategic configuration perspective. We propose that the strategic patterns of EMNEs that deliver growth and/or profitability are characterized by different configurations of environment, strategy, and managerial resource factors. Therefore, identifying and assessing strategic configurations is key to understanding EMNEs’ international performance. Employing fuzzy-set qualitative comparative analysis, we analyze a multi-sourced dataset of Chinese firms’ outward investment and identify multiple equifinal strategic configurations that are associated with superior international performance in terms of sales growth and/or profitability. These findings inform the development of a taxonomy of EMNEs’ strategic configurations corresponding with three performance groups, namely profitable growth, profitable niche, and poor performers.
Publisher: Public Library of Science (PLoS)
Date: 08-09-2016
Publisher: Medknow
Date: 2022
Publisher: Wiley
Date: 25-08-2023
DOI: 10.1111/IJMR.12348
Abstract: Strategic alliances play a vital role in exploration and exploitation activities, otherwise known as the ambidextrous approach for value creation. This has led to an upsurge in studies on ambidexterity in strategic alliances by giving rise to various conceptualizations and theoretical challenges. However, we lack a systematic evaluation and synthesis of the theoretical and empirical insights from this growing body of research. In this paper, we use an integrative systematic literature review (SLR) approach to critically analyse 77 articles on ambidexterity in strategic alliances published in 38 leading journals across 13 disciplines. Findings from bibliometric and qualitative content analyses reveal three major research directions: (1) micro‐foundation and organizational antecedents of ambidexterity in alliances, (2) governance mechanisms of ambidexterity, and (3) relational and performance outcomes of ambidexterity. We integrate these findings into a unified framework which provides a foundation for future research on ambidexterity in strategic alliances, with implications for academics, policymakers and practitioners.
Publisher: Cambridge University Press (CUP)
Date: 09-2016
DOI: 10.1017/MOR.2016.22
Abstract: An institutional perspective has been increasingly adopted in recent studies to explain various aspects of internationalization activities of firms from emerging economies (Meyer & Peng, 2016 Peng, Wang, & Jiang, 2008), particularly China (Cui & Jiang, 2012 Morck, Yeung, & Zhao, 2008). Scholars often claim that the role of institutions in emerging economy firms’ internationalization is understated , hence more research is needed. In this commentary, which reflects on the intended contributions and theoretical and empirical issues of Buckley, Yu, Liu, Munjal, and Tao (2016), I aim to extend a discussion on whether and when such institutional explanations can be overstated . I focus on three issues: (1) conceptualization of institutions, (2) theorizing institutional effects, and (3) testing institutional effects. On each of these issues, I start by providing an overview of some common challenges in the literature. I then focus specifically on the paper as an illustration of how some of these challenges may be manifested. This is then followed by some recommendations for future research. Overall, I argue that pitfalls related to the conceptualization, theorizing and testing of institutional effects can lead researchers to overstate the institutional effects on firm strategic behaviors. These pitfalls can be avoided if researchers clarify the theoretical boundary of the institutional argument they adopt, properly model the institutional effects while taking into consideration other theoretically relevant constructs and mechanisms, and employ empirical design to overcome measurement errors and selection biases when testing not only the statistical significance, but also substantive (economic) significance of institutional effects.
Publisher: Springer Science and Business Media LLC
Date: 06-10-2020
Publisher: Springer Science and Business Media LLC
Date: 12-07-2019
Publisher: Elsevier BV
Date: 04-2022
Publisher: Springer International Publishing
Date: 13-10-2018
Publisher: Elsevier BV
Date: 02-2016
Publisher: Springer International Publishing
Date: 13-10-2018
Publisher: Informa UK Limited
Date: 16-01-2014
Publisher: Springer Science and Business Media LLC
Date: 19-12-2015
Publisher: Elsevier BV
Date: 04-2023
Publisher: Wiley
Date: 02-08-2022
DOI: 10.1002/GSJ.1459
Abstract: This study investigates formal institutional pressure from government policy, informal institutional pressure from filial piety, and their interaction effect on firms' internationalization strategy. We argue that, while influenced by independent policy and cultural effects, firms also exercise agency when responding to these competing institutional pressures. We find empirical support for the influence of policy and cultural effects on firms' foreign direct investment (FDI). We also find that, in making decisions about FDIs, state‐owned enterprises are more sensitive to government policy, whereas family businesses are more sensitive to filial piety. This study reveals that firms' strategies in complex institutional environments are influenced by their needs for formal and informal institutional legitimacy. Managers can exercise agency by weighing the importance of formal and informal legitimacy differently and therefore vary in their responses to institutional pressures. However, managerial agency is bound by firm ownership type. Managers of state‐owned firms prioritize formal institutional legitimacy, while their family business counterparts attend more to informal institutional legitimacy. Policymakers should be aware of this important difference between types of firms, which allows them to address noncompliance in a culturally sensitive and ultimately more effective way.
Publisher: Springer Science and Business Media LLC
Date: 08-07-2014
Publisher: MDPI AG
Date: 11-10-2021
Abstract: Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are two structurally related immunosuppressive peptides. However, the underlying mechanisms through which these peptides regulate microglial activity are not fully understood. Using lipopolysaccharide (LPS) to induce an inflammatory challenge, we tested whether PACAP or VIP differentially affected microglial activation, morphology and cell migration. We found that both peptides attenuated LPS-induced expression of the microglial activation markers Iba1 and iNOS (### p 0.001), as well as the pro-inflammatory mediators IL-1β, IL-6, Itgam and CD68 (### p 0.001). In contrast, treatment with PACAP or VIP exerted distinct effects on microglial morphology and migration. PACAP reversed LPS-induced soma enlargement and increased the percentage of small-sized, rounded cells (54.09% vs. 12.05% in LPS-treated cells), whereas VIP promoted a phenotypic shift towards cell subpopulations with mid-sized, spindle-shaped somata (48.41% vs. 31.36% in LPS-treated cells). Additionally, PACAP was more efficient than VIP in restoring LPS-induced impairment of cell migration and the expression of urokinase plasminogen activator (uPA) in BV2 cells compared with VIP. These results suggest that whilst both PACAP and VIP exert similar immunosuppressive effects in activated BV2 microglia, each peptide triggers distinctive shifts towards phenotypes of differing morphologies and with differing migration capacities.
Publisher: SAGE Publications
Date: 12-10-2016
Abstract: Emerging multinational enterprises (EMNEs) often engage in strategic-asset-seeking foreign direct investment (FDI) for competitive catch-up. This study explores the linkages between an EMNE’s competitive scenario consisting of a configuration of its awareness-motivation-capability (AMC) conditions and the comparative institutional advantages of its strategic-asset-seeking destination. Our configurational analyses of Chinese FDIs in the technology-intensive industries of OECD countries reveal a taxonomy of four distinct asset-seeking strategies of EMNEs. Our findings shed novel insights into the strategic variations within EMNEs based on a theoretically and methodologically extended AMC framework. This study also extends the varieties of capitalism literature by addressing the implications of comparative institutional advantages for foreign entrants, rather than domestic incumbent firms.
Publisher: Elsevier BV
Date: 06-2013
DOI: 10.1016/J.JSR.2013.01.001
Abstract: This study develops an integrative model of safety management based on social cognitive theory and the total safety culture triadic framework. The purpose of the model is to reveal the causal linkages between a hazardous environment, safety climate, and in idual safety behaviors. Based on primary survey data from 209 front-line workers in one of the largest state-owned coal mining corporations in China, the model is tested using structural equation modeling techniques. An employee's perception of a hazardous environment is found to have a statistically significant impact on employee safety behaviors through a psychological process mediated by the perception of management commitment to safety and in idual beliefs about safety. The integrative model developed here leads to a comprehensive solution that takes into consideration the environmental, organizational and employees' psychological and behavioral aspects of safety management.
Publisher: Elsevier BV
Date: 08-2014
Publisher: Elsevier BV
Date: 10-2014
Publisher: Springer Science and Business Media LLC
Date: 13-08-2020
Publisher: Cambridge University Press (CUP)
Date: 07-05-2018
DOI: 10.1017/MOR.2017.47
Abstract: Strategic ambidexterity has been under researched in the context of Chinese outward foreign direct investment (FDI). An ambidextrous FDI, balancing between exploratory and exploitive activities, is strategically desirable but managerially challenging. We examine the role of top management team (TMT) functional ersity in influencing Chinese firms’ degree of FDI ambidexterity, and its boundary conditions in relation to the informal and formal institutional environments within which the TMT operates. Based on a panel of Chinese outward-investing manufacturing firms, our empirical analyses show that a marginal positive effect of TMT functional ersity on a firm's FDI ambidexterity is strengthened by the social faultline presence in the firm's TMT, but is weakened by the development of formal institutions in the firm's external environment.
Publisher: Elsevier BV
Date: 10-2009
Publisher: MDPI AG
Date: 13-02-2018
DOI: 10.3390/JFMK3010013
Publisher: Elsevier BV
Date: 06-2018
Publisher: Springer Science and Business Media LLC
Date: 25-08-2009
DOI: 10.1057/ABM.2009.7
Publisher: Wiley
Date: 21-04-2020
DOI: 10.1111/TWEC.12956
Publisher: Springer Science and Business Media LLC
Date: 09-02-2012
DOI: 10.1057/JIBS.2012.1
Publisher: SAGE Publications
Date: 12-07-2021
DOI: 10.1177/01492063211029708
Abstract: Prior research on the effects of leader humility implies that the more humility the leader exhibits, the greater the positive effect on recipients (e.g., followers and teams). However, little or no attention has so far been paid to the effects on the actors (e.g., leaders), who espouse humble behavior. In response to recent calls to theorize and examine how humility impacts these actors, this research draws on moral licensing theory, adopting an actor-centric approach to examine the mechanisms through which leader humility can lead to unethical behavior, such as unethical behavior for an organization (pseudobeneficial) and unethical behavior toward the organization (detrimental). Ultimately, we propose leader relational accountability as a moderator to mitigate the moral licensing effect of humble leaders. Results from a survey study provide support for the proposed hypotheses.
Publisher: Springer Science and Business Media LLC
Date: 16-07-2020
Start Date: 2015
End Date: 2018
Funder: National Natural Science Foundation of China
View Funded ActivityStart Date: 2013
End Date: 2015
Funder: Australian Research Council
View Funded ActivityStart Date: 2019
End Date: 2022
Funder: National Natural Science Foundation of China
View Funded ActivityStart Date: 2013
End Date: 12-2015
Amount: $365,586.00
Funder: Australian Research Council
View Funded Activity