Donald Grant

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

Publisher: American Association for the Advancement of Science (AAAS)

Date: 07-10-2022

DOI: 10.1126/SCIENCE.ABQ5358

Abstract: Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing in Africa over the past year has led to a major increase in the number of sequences that have been generated and used to track the pandemic on the continent, a number that now exceeds 100,000 genomes. Our results show an increase in the number of African countries that are able to sequence domestically and highlight that local sequencing enables faster turnaround times and more-regular routine surveillance. Despite limitations of low testing proportions, findings from this genomic surveillance study underscore the heterogeneous nature of the pandemic and illuminate the distinct dispersal dynamics of variants of concern—particularly Alpha, Beta, Delta, and Omicron—on the continent. Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve while the continent faces many emerging and reemerging infectious disease threats. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century.

Tulane University

Location: United States of America

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Republic Of Sierra Leone Ministry Of Health And Sanitation

Location: Sierra Leone

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University Of Sierra Leone College Of Medicine And Allied Health Sciences

Location: Sierra Leone

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