Publication
Evidence for the Effectiveness of Psychological Interventions for Internalized Stigma among Adults with Schizophrenia Spectrum Disorders: A Systematic Review and Meta-Analyses
Publisher:
MDPI AG
Date:
18-04-2023
DOI:
10.3390/IJERPH20085570
Abstract: In recent years, psychological interventions have been used to alleviate internalized stigma in people with schizophrenia spectrum disorders, but outcomes have been inconsistent. The aim of this review was to examine the existing evidence regarding this matter. Four electronic databases (EMBASE, MEDLINE, PsycINFO, and the Cochrane Central Register of Controlled Trials) were searched from inception until 8 September 2022, using appropriate strategies. The eligibility, quality, and strength of evidence of each study were all evaluated against the predetermined standards. Further quantitative analyses were performed using the RevMan software. A total of 27 studies were included in the systematic review. Eighteen studies with extractable data for meta-analysis yielded a statistically significant overall effect (Z = 3.00 p = 0.003 95% CI: −0.69 [−1.15, −0.24] n = 1633), although there was considerable heterogeneity (Tau2 = 0.89 Chi2 = 303.62, df = 17 p 0.00001 I2 = 94%). Subgroup analyses for Narrative Enhancement and Cognitive Therapy (NECT) produced a statistically significant and highly homogenous effect (Z = 3.40 p = 0.0007 95% CI: −0.44 [−0.70, −0.19] n = 241 Tau2 = 0.00 Chi2 = 0.14, df = 2 (p = 0.93) I2 = 0%). In conclusion, the majority of the psychological interventions are successful in lowering levels of internalized stigma, especially NECT, and interventions that integrate multiple therapies may be more beneficial.