ORCID Profile
0000-0003-1411-9806
Current Organisation
James Cook University
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Publisher: Wiley
Date: 26-02-2009
Publisher: Wiley
Date: 08-01-2016
DOI: 10.1111/VCP.12310
Abstract: Portable blood glucose meters (PBGM, glucometers) are a convenient, cost effective, and quick means to assess patient blood glucose concentration. The number of commercially available PBGM is constantly increasing, making it challenging to determine whether certain glucometers may have benefits over others for veterinary testing. The challenge in selection of an appropriate glucometer from a quality perspective is compounded by the variety of analytic methods used to quantify glucose concentrations and disparate statistical analysis in many published studies. These guidelines were developed as part of the ASVCP QALS committee response to establish recommendations to improve the quality of testing using point-of-care testing (POCT) handheld and benchtop devices in veterinary medicine. They are intended for clinical pathologists and laboratory professionals to provide them with background knowledge and specific recommendations for quality assurance (QA) and quality control (QC), and to serve as a resource to assist the provision of advice to veterinarians and technicians to improve the quality of results obtained when using PBGM. These guidelines are not intended to be all-inclusive rather they provide a minimum standard for management of PBGM in the veterinary setting.
Publisher: Wiley
Date: 02-02-2023
DOI: 10.1111/JSAP.13588
Abstract: To compare the ionised calcium measured on a portable analyser (iSTAT, Abbott) to a reference method. Blood s les from 39 apparently healthy dogs were analysed in duplicate using a portable analyser and a reference method (Radiometer ABL800 FLEX). Bland–Altman plots and Passing–Bablok regression were used to assess constant and proportional bias between the two instruments. A within‐assay percentage coefficient of variation and total error (TE) was calculated for both analysers. The reference interval was calculated for the portable analyser using the robust method with confidence interval bootstrapping. The Bland–Altman plot showed a −0.036 mmol/L difference between the two instruments (95% confidence limit −0.08 to 0.01 mmol/L limits of agreement −0.07 to 0.006 mmol/L). Neither the Bland–Altman plot nor the Passing–Bablock regression (slope −0.03 95% confidence interval −0.08 to 0.19 and intercept 1 95% confidence interval 0.83 to 1.2) showed significant proportional bias. The coefficient of variation for the portable analyser was 1.08%, compared to 0.78% for the reference method with a total error of 3.5% for the portable analyser. The estimated population‐based reference interval for ionised calcium using the portable analyser is 1.23 to 1.42 mmol/L. For the healthy dogs in this study, compared to the reference method, the portable analyser showed no significant bias for measurement of ionised calcium. Further studies including hyper and hypocalcaemic dogs are required to determine clinical impact of the use of this analyser.
Publisher: SAGE Publications
Date: 12-2010
DOI: 10.1016/J.JFMS.2010.08.003
Abstract: The significance of mastocytaemia in cats is different from that in dogs because it appears exclusively associated with mast cell neoplasia. The prevalence of mastocytaemia was 0.05% of all feline submissions to a private laboratory and 43% in cats with mast cell neoplasia. None of 30 healthy cats had mastocytaemia. There was no sex bias or significant age difference between mastocytaemic and non-mastocytaemic cats with mast cell tumours (MCT). Buffy coat (BC) examination was the best screening method for detection of mastocytaemia but direct blood film examination was more accurate for quantifying degree of mastocytaemia. BC examination should be performed in all cases of suspected/known mast cell neoplasia as mastocytaemia was missed on nearly 30% of occasions when direct film examination only was used. Mastocytaemia was associated with decreased haematocrit (HCT) but not with other haematological parameters. Mastocytaemic cats can survive significant lengths of time (up to 27 months) even when splenectomy is not performed.
No related grants have been discovered for Karen Gerber.