ORCID Profile
0000-0002-9083-3131
Current Organisation
James Cook University
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Publisher: SAGE Publications
Date: 07-2019
Abstract: The literature on the production of high-tech electronics in China—following a Silicon Valley model—focuses on either large-scale manufacturing or the role of start-ups and ‘makers’. The aim of this article is to turn to other kinds of spaces and work in the production of high-tech electronics. I focus here on three kinds of spaces in Shenzhen: the Huaqiangbei electronics market, small-scale factories and industrial design workshops. The electronics economy depends critically not just on ‘makers’ but on all kinds of other labour. In particular, it depends on lower middle-class and low-class work—devices made by small factories and shops, sold by small enterprises and designed for the less wealthy, especially in developing countries. The human networks that connect these in iduals are critical to the size, speed and density of the markets, allowing devices to be built and shipped rapidly, for parts and customers to be available.
Publisher: Informa UK Limited
Date: 02-01-2021
Publisher: Springer Science and Business Media LLC
Date: 28-08-2020
Publisher: Wiley
Date: 13-02-2020
Publisher: Project MUSE
Date: 2016
Publisher: University of Illinois Libraries
Date: 04-2019
Abstract: In 2011, Singapore created data.gov.sg as an open, online repository for government data. This essay examines this Web portal, the data it contains, and some of the applications that have been built using it and aims to understand the role that data.gov.sg plays within the context of Singapore’s continued political and economic development. Although such portals and the data they contain are often presented as offering transformative modes of governance and democratic participation, analysis of data.gov.sg shows how the data portal can act to reinforce and entrench existing modes of governance.
Publisher: University of Illinois Libraries
Date: 04-2019
Abstract: This special issue looks closely at contemporary data systems in erse global contexts and through this set of papers, highlights the struggles we face as we negotiate efficiency and innovation with universal human rights and social inclusion. The studies presented in these essays are situated in erse models of policy-making, governance, and/or activism across borders. Attention to big data governance in western contexts has tended to highlight how data increases state and corporate surveillance of citizens, affecting rights to privacy. By moving beyond Euro-American borders — to places such as Africa, India, China, and Singapore — we show here how data regimes are motivated and understood on very different terms.
Publisher: University of Chicago Press
Date: 2013
Publisher: University of Chicago Press
Date: 03-2012
DOI: 10.1086/670905
Publisher: Springer Science and Business Media LLC
Date: 31-03-2015
Publisher: University of Chicago Press
Date: 2016
Publisher: Wiley
Date: 02-11-2011
Publisher: University of Texas Press
Date: 11-2015
DOI: 10.7560/IC50402
Publisher: Duke University Press
Date: 15-04-2015
Publisher: The Royal Australian College of General Practitioners
Date: 12-2018
Publisher: SAGE Publications
Date: 15-04-2021
DOI: 10.1177/01622439211005021
Abstract: Who gets to practice and participate in science? Research teams in Puerto Rico and New Zealand have each sequenced the genomes of parrot populations native to these locales: the iguaca and kākāpō, respectively. In both cases, crowdfunding and social media were instrumental in garnering public interest and funding. These forms of Internet-mediated participation impacted how conservation science was practiced in these cases and shaped emergent social roles and relations. As citizens “follow,” fund, and “like” the labor of conservation, they create new relational possibilities for and with science. For ex le, the researchers became newly engaged and engaging by narrating and displaying the parrots via an Internet-inflected aesthetic. The visibility of online modalities shifted accountabilities as researchers considered whom this crowdfunded work answered to and how to communicate their progress and results. The affordances of the Internet allowed researchers from the peripheries of the scientific establishment to produce genomic knowledge for globally dispersed audiences. The convergence of genomic and Internet technology here shaped scientific practice by facilitating new modes of participation—for laypeople in science but also for scientists in society.
Publisher: University of California Press
Date: 2003
DOI: 10.1525/HSPS.2003.34.1.151
Abstract: The justifications for public expenditure on accelerator laboratories that high energy physicists deployed over the course of the Cold War are examined.It is shown how legitimization in terms of Cold War economic and national security aims was rendered ineffective during the 1960s anti-science movements. As a consequence high energy physicists framed a response that emphasized the elegance and cultural value of their work. Their story vaunted universal and fundamental concepts that could be appreciated by even an anti-scientific audience. In particular, the concept of “symmetry,” which had become a powerful tool of high energy physics, was utilized to communicate the aesthetic qualities toward which the physicists aspired. Robert Wilson realized this vision in his design and successful construction and operation of the Fermi National Accelerator Laboratory (1967-1974). During the 1980s, renewed Cold War tensions, string theory, and challenges from condensed matter physicists fragmented the physics community and broke down the high energy physicists' symmetry narrative. The multiplicity of competing stories about fundamental physics that resulted are considered as one cause of the 1993 cancellation of the Superconducting Super Collider.
Publisher: Apollo - University of Cambridge Repository
Date: 2019
DOI: 10.17863/CAM.40310
Publisher: Elsevier BV
Date: 2021
Publisher: MIT Press - Journals
Date: 09-2011
DOI: 10.1162/POSC_A_00042
Publisher: Proceedings of the National Academy of Sciences
Date: 13-01-2011
Abstract: Resistance to tamoxifen in breast cancer patients is a serious therapeutic problem and major efforts are underway to understand underlying mechanisms. Resistance can be either intrinsic or acquired. We derived a series of subcloned MCF7 cell lines that were either highly sensitive or naturally resistant to tamoxifen and studied the factors that lead to drug resistance. Gene-expression studies revealed a signature of 67 genes that differentially respond to tamoxifen in sensitive vs. resistant subclones, which also predicts disease-free survival in tamoxifen-treated patients. High-throughput cell-based screens, in which human kinases were independently ectopically expressed, identified 31 kinases that conferred drug resistance on sensitive cells. One of these, HSPB8, was also in the expression signature and, by itself, predicted poor clinical outcome in one cohort of patients. Further studies revealed that HSPB8 protected MCF7 cells from tamoxifen and blocked autophagy. Moreover, silencing HSBP8 induced autophagy and caused cell death. Tamoxifen itself induced autophagy in sensitive cells but not in resistant ones, and tamoxifen-resistant cells were sensitive to the induction of autophagy by other drugs. These results may point to an important role for autophagy in the sensitivity to tamoxifen.
Publisher: University of California Press
Date: 04-2016
Publisher: SAGE Publications
Date: 24-04-2015
Abstract: The last decade has seen the increased use of direct-to-consumer genetic testing for constructing genealogies. These services, offered by companies such as 23andMe, combine biotechnology with new media technologies such as blogging and social networking. In idual consumers are able to construct new identities, communities, and personal histories on the basis of their DNA. Such technology-based and technology-mediated historical reconstructions have the potential to reshape our relationship to the past. In particular, DNA histories entail a particular notion of temporality, specific standards of evidence, and a particular vision of identity. By analyzing the development and use of these new technologies, we can begin to identify specific ways in which biotechnologies and new media technologies are impacting the construction of social memory in the twenty-first century.
Publisher: Springer Science and Business Media LLC
Date: 28-01-2014
Publisher: Project MUSE
Date: 2015
Abstract: The wide sharing of biological data, especially nucleotide sequences, is now considered to be a key feature of genomics. Historians and sociologists have attempted to account for the rise of this sharing by pointing to precedents in model organism communities and in natural history. This article supplements these approaches by examining the role that electronic networking technologies played in generating the specific forms of sharing that emerged in genomics. The links between early computer users at the Stanford Artificial Intelligence Laboratory in the 1960s, biologists using local computer networks in the 1970s, and GenBank in the 1980s, show how networking technologies carried particular practices of communication, circulation, and data distribution from computing into biology. In particular, networking practices helped to transform sequences themselves into objects that had value as a community resource.
Publisher: Informa UK Limited
Date: 26-05-2021
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 02-2018
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2021
Publisher: American Association for the Advancement of Science (AAAS)
Date: 05-02-2021
Abstract: Millions of people today have access to their personal genomic information. Direct-to-consumer services and integration with other “big data” increasingly commoditize what was rightly celebrated as a singular achievement in February 2001 when the first draft human genomes were published. But such remarkable technical and scientific progress has not been without its share of missteps and growing pains. Science invited the experts below to help explore how we got here and where we should (or ought not) be going.
Publisher: Project MUSE
Date: 2015
Publisher: American Chemical Society (ACS)
Date: 21-05-2005
DOI: 10.1021/LA0507535
Abstract: The long-ranged attractions between hydrophobic amorphous fluoropolymer surfaces are measured in water with and without dissolved air. An atomic force microscope is used to obtain more than 500 measured jump-in distances, which yields statistically reliable results. It is found that the range of the attraction and its variability is generally significantly decreased in deaerated water as compared to normal, aerated water. However, the range and strength of the attraction in deaerated water remain significantly greater than the van der Waals attraction for this system. The experimental observations are consistent with (1) nanobubbles being primarily responsible for the long-ranged attraction in normal water, (2) nanobubbles not being present in deaerated water when the surfaces are not in contact, and (3) the attraction in the absence of nanobubbles being most probably due to the approach to the separation-induced spinodal cavitation of the type identified by Bérard et al. [J. Chem. Phys. 1993, 98, 7236]. It is argued that the measurements in deaerated water reveal the bare or pristine hydrophobic attraction unobscured by nanobubbles.
Publisher: Springer Science and Business Media LLC
Date: 14-09-2015
Publisher: Springer Science and Business Media LLC
Date: 06-10-2018
DOI: 10.1007/S10739-017-9490-Y
Abstract: Genomics is increasingly considered a global enterprise – the fact that biological information can flow rapidly around the planet is taken to be important to what genomics is and what it can achieve. However, the large-scale international circulation of nucleotide sequence information did not begin with the Human Genome Project. Efforts to formalize and institutionalize the circulation of sequence information emerged concurrently with the development of centralized facilities for collecting that information. That is, the very first databases build for collecting and sharing DNA sequence information were, from their outset, international collaborative enterprises. This paper describes the origins of the International Nucleotide Sequence Database Collaboration between GenBank in the United States, the European Molecular Biology Laboratory Databank, and the DNA Database of Japan. The technical and social groundwork for the international exchange of nucleotide sequences created the conditions of possibility for imagining nucleotide sequences (and subsequently genomes) as a “global” objects. The “transnationalism” of nucleotide sequence was critical to their ontology – what DNA sequences came to be during the Human Genome Project was deeply influenced by international exchange.
Publisher: University of Chicago Press
Date: 09-2017
DOI: 10.1086/693516
Publisher: Oxford University Press (OUP)
Date: 12-2016
Publisher: Project MUSE
Date: 2018
Publisher: Informa UK Limited
Date: 09-2020
Publisher: Springer Science and Business Media LLC
Date: 21-02-2011
Publisher: Springer Science and Business Media LLC
Date: 09-2016
Publisher: University of Chicago Press
Date: 10-2018
DOI: 10.1086/699235
No related grants have been discovered for Hallam Stevens.