ORCID Profile
0000-0002-2355-5979
Current Organisation
TianGong University
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Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 26-12-2006
Publisher: Springer Science and Business Media LLC
Date: 05-11-2008
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 28-05-2008
Publisher: Wiley
Date: 22-07-2008
DOI: 10.1002/MDS.22186
Publisher: MDPI AG
Date: 13-08-2022
Abstract: Edible oil blends are composed of two or more edible oils in varying proportions, which can ensure nutritional balance compared to oils comprising a single component oil. In view of their economical and nutritional benefits, quantitative analysis of the component oils in edible oil blends is necessary to ensure the rights and interests of consumers and maintain fairness in the edible oil market. Chemometrics combined with modern analytical instruments has become a main analytical technology for the quantitative analysis of edible oil blends. This review summarizes the different oil blend design methods, instrumental techniques and chemometric methods for conducting single component oil quantification in edible oil blends. The aim is to classify and compare the existing analytical techniques to highlight suitable and promising determination methods in this field.
Publisher: Springer Science and Business Media LLC
Date: 29-06-2008
Publisher: American Medical Association (AMA)
Date: 06-2006
DOI: 10.1001/ARCHNEUR.63.6.826
Abstract: The PARK2 gene at 6q26 encodes parkin, whose inactivation is implicated in an early-onset autosomal recessive form of Parkinson disease (PD). To evaluate the influence of heterozygosity for parkin mutation on onset age in a s le of families with at least 2 PD-affected members. Clinical and genetic study. Twenty collaborative clinical sites. Patients with familial PD collected in the GenePD study. Studied families were selected for (1) affected sibling pairs sharing 2 alleles identical by state at PARK2 (D6S305) or (2) 1 or more family members with onset age younger than 54 years, regardless of D6S305 status. At least 1 member from each of 183 families underwent comprehensive screening for deletion/insertion variants and point mutations in PARK2. Mutations in the parkin gene were screened by means of single-stranded conformation polymorphism and sequencing in all 12 coding exons and flanking intronic sequences for point mutations and duplex quantitative polymerase chain reaction in all exons for rearrangement, duplication, and deletion. Mutations were found in 23 families (12.6% of those screened). Among the mutation-positive families, 10 (43%) contained compound heterozygotes 3 (13%), homozygotes and 10 (43%), heterozygotes. The onset age in patients with parkin gene mutations ranged from 20 to 76 years. Patients with 1 parkin mutation had an 11.7-year age at onset than did patients with none (P = .04), and patients with 2 or more parkin mutations had a 13.2-year decrease in age at onset compared with patients with 1 mutation (P = .04). These data indicate that parkin mutations are not rare in multiply affected sibships, and that heterozygous mutation carrier status in PARK2 significantly influences age at onset of PD.
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 12-12-2005
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Marie-Helene Saint-Hilaire.