ORCID Profile
0000-0003-2317-6511
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Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 12-2016
Publisher: AIP Publishing
Date: 10-2017
DOI: 10.1063/1.5006520
Abstract: The extremely low frequency electromagnetic fields (ELF-EMFs) have been shown to have an environmentally negative effect on humans’ health however, its treatment effect is beneficial for patients suffering from neurological disorders. Despite this success, the application of ELF-EMF has exceeded in the understanding of its internal mechanism. Recently, it was found that on-line magnetic stimulation may offer advantages over off-line magnetic exposure and has proven to be effective in activating the prefrontal cortex pyramidal neurons in vitro. Here, we perform computational simulations of the stimulation coils in COMSOL modeling to describe the uniformity of the distribution of the on-line magnetic field. Interestingly, the modeling data and actual measurements showed that the densities of the magnetic flux that was generated by the on-line stimulation coils were similar. The on-line magnetic stimulator induced sodium channel currents as well as field excitatory postsynaptic potentials of the rat hippoc al CA1 neurons and successfully demonstrated its extensive applications to activate neuronal tissue. These findings further raise the possibility that the instrument of on-line magnetic stimulation may be an effective alternative for studies in the field of bioelectromagnetics.
Publisher: Informa UK Limited
Date: 13-06-2019
Publisher: Springer Science and Business Media LLC
Date: 24-06-2017
DOI: 10.1007/S00232-017-9967-9
Abstract: Electric fields (EF) can induce some physiological or biological effects in neural tissues, which have been explored in many applications such as electroporation. The key to understand the possible underlying mechanisms of such effects tend to be the induced transmembrane potential. Although transmembrane potentials have already been the subject of many theoretical studies, most previous works concerning this topic are mainly focused on the situations of isolated cells. In previous studies, cells are often considered to be three-compartment models with different electroconductivities in different regions (the three compartments are often intracellular regions, membrane, and extracellular regions). In the present paper, we utilize a finite element method (FSM) (with the help of COMSOL
Publisher: Wiley
Date: 09-03-2020
DOI: 10.1111/EJN.14705
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2021
No related grants have been discovered for Yu Zheng.