ORCID Profile
0000-0003-1877-2474
Current Organisations
University of Southampton
,
University of Melbourne
,
Southampton General Hospital
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Publisher: Springer Science and Business Media LLC
Date: 28-02-2018
DOI: 10.1038/S41467-018-03290-0
Abstract: Layered van der Waals materials are emerging as compelling two-dimensional platforms for nanophotonics, polaritonics, valleytronics and spintronics, and have the potential to transform applications in sensing, imaging and quantum information processing. Among these, hexagonal boron nitride (hBN) is known to host ultra-bright, room-temperature quantum emitters, whose nature is yet to be fully understood. Here we present a set of measurements that give unique insight into the photophysical properties and level structure of hBN quantum emitters. Specifically, we report the existence of a class of hBN quantum emitters with a fast-decaying intermediate and a long-lived metastable state accessible from the first excited electronic state. Furthermore, by means of a two-laser repumping scheme, we show an enhanced photoluminescence and emission intensity, which can be utilized to realize a new modality of far-field super-resolution imaging. Our findings expand current understanding of quantum emitters in hBN and show new potential ways of harnessing their nonlinear optical properties in sub-diffraction nanoscopy.
Publisher: Oxford University Press (OUP)
Date: 06-09-2022
Abstract: COVID-19 is associated with neurological complications including stroke, delirium and encephalitis. Furthermore, a post-viral syndrome dominated by neuropsychiatric symptoms is common, and is seemingly unrelated to COVID-19 severity. The true frequency and underlying mechanisms of neurological injury are unknown, but exaggerated host inflammatory responses appear to be a key driver of COVID-19 severity. We investigated the dynamics of, and relationship between, serum markers of brain injury [neurofilament light (NfL), glial fibrillary acidic protein (GFAP) and total tau] and markers of dysregulated host response (autoantibody production and cytokine profiles) in 175 patients admitted with COVID-19 and 45 patients with influenza. During hospitalization, sera from patients with COVID-19 demonstrated elevations of NfL and GFAP in a severity-dependent manner, with evidence of ongoing active brain injury at follow-up 4 months later. These biomarkers were associated with elevations of pro-inflammatory cytokines and the presence of autoantibodies to a large number of different antigens. Autoantibodies were commonly seen against lung surfactant proteins but also brain proteins such as myelin associated glycoprotein. Commensurate findings were seen in the influenza cohort. A distinct process characterized by elevation of serum total tau was seen in patients at follow-up, which appeared to be independent of initial disease severity and was not associated with dysregulated immune responses unlike NfL and GFAP. These results demonstrate that brain injury is a common consequence of both COVID-19 and influenza, and is therefore likely to be a feature of severe viral infection more broadly. The brain injury occurs in the context of dysregulation of both innate and adaptive immune responses, with no single pathogenic mechanism clearly responsible.
Publisher: The Optical Society
Date: 27-11-2019
DOI: 10.1364/OL.44.005792
Publisher: Optica Publishing Group
Date: 22-01-2021
DOI: 10.1364/OL.416564
Abstract: Hexagonal boron nitride (hBN) is a layered dielectric material with a wide range of applications in optics and photonics. In this work, we demonstrate a fabrication method for few-layer hBN flakes with areas up to 5000 µ m 2 . We show that hBN in this form can be integrated with photonic microstructures: as an ex le, we use a circular Bragg grating (CBG). The layer quality of the exfoliated hBN flake on and off a CBG is confirmed by Raman spectroscopy and second-harmonic generation (SHG) microscopy. We show that the SHG signal is uniform across the hBN s le outside the CBG and is lified in the center of the CBG.
Publisher: American Chemical Society (ACS)
Date: 30-04-2021
Publisher: American Chemical Society (ACS)
Date: 12-06-2020
Publisher: American Chemical Society (ACS)
Date: 24-02-2021
Publisher: Wiley
Date: 13-01-2023
Abstract: 2D materials, with distinct characteristics compared to their conventional bulk counterparts, have been a popular topic in various optoelectronic research fields. Herein, indium selenide (InSe), a monochalcogenide van der Waals layered semiconductor, which has been studied due to its thickness dependent optical characteristics is explored. For InSe to be used as a versatile light source, enhancing the emission of InSe is required. Here, enhanced photoluminescence (PL) from multi‐layer InSe is demonstrated using a gap plasmon induced between Ag nanocube dimer and an Au substrate. Such plasmonic structures support multiple resonances, one of those overlapping with InSe's band edge PL emission. The calculated Purcell factor shows a 200‐fold increase on the short edge of nanocube dimers. Experimentally, PL enhancement of 6‐fold is demonstrated at room temperature. In addition, a method for determining the thickness of 2D materials via dark‐field spectroscopy using white light illumination is shown. This study paves the way for the incorporation of 2D InSe into nanophotonic structures.
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: Korea, Republic of
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Emma Norton.