ORCID Profile
0000-0001-6445-7737
Current Organisation
Tianjin University
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Publisher: American Chemical Society (ACS)
Date: 29-01-2018
Publisher: Elsevier BV
Date: 06-2019
Publisher: Bentham Science Publishers Ltd.
Date: 15-10-2018
DOI: 10.2174/1381612824666180522102732
Abstract: The development of solid drug dosage form and food ingredients is constrained by their low solubility, low dissolution, low bioavailability and poor physicochemical properties. Formation of cocrystal is a novel and promising method to enhance and improve the properties of materials without breaking the covalent bonds. The goal of this review is to summarize the cocrystals and their applications in the field of Active Pharmaceutical Ingredients (APIs) and food ingredients (AFIs), mainly on the effective improvements of APIs’ and AFIs’ pharmacokinetic, physicochemical and mechanical properties by the formation of cocrystals. After years of research and development on cocrystals in the area of pharmaceutical and food industries, significant progress has been made. Formation of cocrystal is an efficient method for improving the solubility, dissolution rate, permeability and in vivo bioavailability of APIs and AFIs, as well as for enhancing stability and mechanical properties. Cocrystals exhibit complex structures which can conspicuously affect the physical and chemical properties of original substance, with good clinical performance and outstanding stability during processing and storage.
Publisher: Elsevier BV
Date: 06-2019
Publisher: American Chemical Society (ACS)
Date: 16-12-2016
Publisher: MDPI AG
Date: 17-07-2018
DOI: 10.3390/NANO8070537
Abstract: Recyclable nanomaterials are in great need to develop clean technology for applications in the removal of water contaminants. In this work, easily separable montmorillonite/Fe3O4/humic acid (MFH) nanocomposites were fabricated through a facile hydrothermal route. It was found the adsorption ability and stability of MFH was significantly enhanced due to the synergistic effects between montmorillonite, Fe3O4 nanoparticles and humic acid. The MFH nanocomposites are highly efficient and recyclable as they can remove at least 82.3% of Cr(VI) and 95.1% of aniline in six consecutive runs. The adsorption mechanism was investigated by analyzing the kinetic parameters of pseudo first-order, pseudo second-order, and intraparticle diffusion models and describing the equilibrium isotherms of Langmuir and Freundlich models. Results indicated different adsorption mechanisms of Cr(VI) and aniline by MFH. The readily synthesized MFH nanocomposites can act as effective and practical materials for environmental applications.
Publisher: Elsevier BV
Date: 02-2019
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C8DT05072D
Abstract: A simple one-step synthetic route to access a range of metal-doped polyoxovanadate clusters.
Publisher: MDPI AG
Date: 30-09-2017
DOI: 10.3390/NANO7100303
Publisher: Elsevier BV
Date: 04-2017
DOI: 10.1016/J.CHEMOSPHERE.2017.01.070
Abstract: As a by-product of industrial or domestic activities, wastewater of different compositions has caused serious environmental problems all over the world. Facing the challenge of wastewater treatment, researchers have begun to make use of crystallization techniques in wastewater treatment. Crystallization techniques have many advantages, such as high efficiency, energy saving, low costs, less space occupation and so on. In recent decades, crystallization is considered as one of promising techniques for wastewater treatment, especially for desalination, water and salt recovery. It has been widely used in engineering applications all over the world. In this paper, various crystallization techniques in wastewater treatment are summarized, mainly including evaporation crystallization, cooling crystallization, reaction crystallization, drowning-out crystallization and membrane distillation crystallization. Overall, they are mainly used for desalination, water and salt recovery. Their applications, advantages and disadvantages were compared and discussed in detail.
Publisher: Hindawi Limited
Date: 2016
DOI: 10.1155/2016/4964828
Abstract: Due to the exceptional characteristics which resulted from nanoscale size, such as improved catalysis and adsorption properties as well as high reactivity, nanomaterials have been the subject of active research and development worldwide in recent years. Numerous studies have shown that nanomaterials can effectively remove various pollutants in water and thus have been successfully applied in water and wastewater treatment. In this paper, the most extensively studied nanomaterials, zero-valent metal nanoparticles (Ag, Fe, and Zn), metal oxide nanoparticles (TiO 2 , ZnO, and iron oxides), carbon nanotubes (CNTs), and nanocomposites are discussed and highlighted in detail. Besides, future aspects of nanomaterials in water and wastewater treatment are discussed.
Publisher: Elsevier BV
Date: 10-2017
Publisher: Wiley
Date: 18-04-2018
Publisher: Elsevier BV
Date: 2020
Publisher: Wiley
Date: 04-10-2018
Abstract: Single-source precursors are used to produce nanostructured BiVO
Publisher: Royal Society of Chemistry (RSC)
Date: 2016
DOI: 10.1039/C6NR00740F
Abstract: An overview of the mechanism, synthesis and modification of nano zerovalent iron in water treatment is provided.
Publisher: Elsevier BV
Date: 07-2017
Publisher: Hindawi Limited
Date: 2016
DOI: 10.1155/2016/5762431
Abstract: With the rapid development of nanotechnology, the convergence of nanostructures and drug delivery has become a research hotspot in recent years. Due to their unique and superior properties, various nanostructures, especially those fabricated from self-assembly, are able to significantly increase the solubility of poorly soluble drugs, reduce cytotoxicity toward normal tissues, and improve therapeutic efficacy. Nanostructures have been successfully applied in the delivery of erse drugs, such as small molecules, peptides, proteins, and nucleic acids. In this paper, the driving forces for the self-assembly of nanostructures are introduced. The strategies of drug delivery by nanostructures are briefly discussed. Furthermore, the emphasis is put on a variety of nanostructures fabricated from various building materials, mainly liposomes, polymers, ceramics, metal, peptides, nucleic acids, and even drugs themselves.
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7CE00713B
Abstract: Schematic diagram of MC_U cocrystal formation during cooling crystallization, represented by real-time Raman, ATR-FTIR and FBRM data.
No related grants have been discovered for Hongxun Hao.