ORCID Profile
0000-0001-6636-7145
Current Organisations
Stanford University
,
Leibniz-Institut für Festkörper- und Werkstoffforschung Dresden eV
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Publisher: Springer Science and Business Media LLC
Date: 05-2018
Publisher: Proceedings of the National Academy of Sciences
Date: 05-11-2021
Abstract: Spatial organization of mitochondria is vital for cellular function. In many specialized cell types, mitochondria are immobilized at specific subcellular loci through interactions with the cytoskeleton. One of the most striking mitochondrial configurations occurs in mammalian sperm, where mitochondria wrap around the flagellum. Malformation of the mitochondrial sheath causes infertility, but the molecular structures underlying this intricate arrangement are unknown. Here, we analyzed the mitochondrial sheath in sperm from three mammalian species. We find that although mitochondrial dimensions and cristae architecture vary across species, molecular assemblies mediating intermitochondria and mitochondria–cytoskeleton interactions are conserved. These findings yield important insight into sperm physiology and evolution and are relevant for other polarized cell types, such as muscles, neurons, photoreceptors, and hair cells.
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D0CP06518H
Abstract: The stoichiometry of g-C 3 N 4 tailored by electron beam irradiation. The data show degradation of g-C 3 N 4 with preferential removal of N species over C species and that inelastic scattering events dominate over elastic events.
Location: Germany
No related grants have been discovered for Johannes Florian Hevler.