ORCID Profile
0000-0002-6443-6992
Current Organisations
University of Adelaide
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University of Groningen
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Publisher: Elsevier BV
Date: 05-2021
Publisher: Korean Society of Occupational and Environmental Medicine
Date: 23-03-2017
Publisher: American Medical Association (AMA)
Date: 28-08-2018
Publisher: JMIR Publications Inc.
Date: 22-02-2022
Abstract: ny infectious diseases outbreak may lead to negative detrimental psychological impact to in iduals and community at large, however there was no systematic review nor meta-analysis that examined the relationship between early stages of infectious disease outbreaks and mental health in Asia. his research gap gave us the impetus to conduct this study which aimed at disentangling the relationship between infectious disease outbreaks and psychological well-being of affected in iduals (survivors/suspected cases), healthcare workers and the general public. systematic search was conducted using PubMed, EMBASE, Medline, PsycINFO, and CINAHL databases from 1/1/2000 to 1/6/2020 following the PRISMA guidelines. Manual search was also performed to identify additional relevant studies. Due to heterogeneity, a subgroup analysis was also conducted. Joanna Briggs Institute (JBI) Critical Appraisal tools was used to appraise the quality for cohort studies. In this systematic review and meta-analysis, we analyzed the psychological impact on confirmed/suspected cases, healthcare workers and the general public during the Severe Acute Respiratory Syndrome (SARS) outbreak and Coronavirus disease (COVID-19) epidemics. Primary outcomes included prevalence of depression, anxiety, stress, post-traumatic stress disorder, aggression, sleeping problems and psychological symptoms. wenty-three eligible studies (N=27,325) were included. Random effect model was used to analyze the data using STATA. Of these studies, 11 were related to the SARS outbreak and 12 related to COVID-19 outbreaks. The overall prevalence rate of anxiety during SARS and COVID-19 was 37.8% (95% CI: 21.1- 54.5, P .001, I2 = 96.9%) and 34.8% (95% CI: 29.1- 40.4), respectively. For depression, the overall prevalence rate during SARS and COVID-19 was 30.9% (95% CI: 18.6-43.1, P .001, I2 = 97.3%) and 32.4% (95% CI: 19.8-45.0, P .001, I2 = 99.8%), respectively. The overall prevalence rate of stress was 9.4% (95% CI: -0.4 -19.2, P = 0.015, I2 = 83.3%) and 54.1% (95% CI: 35.7- 72.6, P .001, I2 = 98.8%) during SARS and COVID-19, respectively. The overall prevalence of PTSD was 15.1% (95% CI: 8.2-22.0, P 0.001) during SARS epidemic, calculated by random-effects model (P 0.05), with significant between-study heterogeneity (I2 = 93.5%). he SARS and COVID-19 epidemics have brought about high levels of psychological distress to in iduals. Psychological interventions and contingent digital mental health platform should be promptly established nationwide for continuous surveillance of the increasing prevalence of negative psychological symptoms. Health policymakers and mental health experts should jointly collaborate to provide timely, contingent mental health treatment and psychological support to those in need to reduce the global disease burden. his study was approved by the Human Subjects Ethics Sub-committee of the Hong Kong Polytechnic University (reference no: HSEARS20200227002-01). Participants provided their written informed consent prior to participation online. Participants were assured of their anonymity and confidentiality, and their rights of withdrawal were respected.
Publisher: Springer Science and Business Media LLC
Date: 2021
Publisher: Springer Science and Business Media LLC
Date: 18-09-2018
DOI: 10.1007/S00394-018-1817-8
Abstract: The aim of this systematic review and meta-analysis was to provide a national estimate of breast and complementary feeding practices and its predictors in Ethiopia. PubMed, SCOPUS, EMBASE, CINHAL, Web of Science and WHO Global Health Library electronic databases were searched for all available literature published until April 2018. Observational studies including cross-sectional, case-control and cohort studies were included. Newcastle-Ottawa Scale was used to assess the quality of studies. Heterogeneity of studies was quantified using Cochran's Q χ In total, 70 studies that involved > 55,000 women from nine regions and two chartered cities in Ethiopia were included. The pooled national prevalence for timely initiation of breastfeeding (TIBF), exclusive breastfeeding (EBF) and timely initiation of complementary feeding was 66.5%, 60.1% and 62.5%, respectively. Guidance and counselling on breastfeeding, vaginal delivery and health institution delivery significantly increased the odds of TIBF and EBF. In addition, TIBF significantly associated with high EBF practice. Maternal occupational status significantly associated with low EBF practice, but not TIBF. Based on the WHO standard, the current breast and complementary feeding practice in Ethiopia is good and improving. Integrated intervention is still required for further improvement and minimizing the effect of occupational status.
Publisher: Cold Spring Harbor Laboratory
Date: 16-05-2022
DOI: 10.1101/2022.05.16.22275144
Abstract: Despite the rise in the number of systematic reviews (SR) and meta-analyses (MA) in medicine and health science fields in Ethiopia, there is limited up-to-date evidence on their methodological and reporting quality for using them in decision-making. The aim of this study was to characterize epidemiological trends and evaluate the methodological and reporting quality of SR and MA in Ethiopia. A retrospective observational overview study was conducted on SR and MA in medicine and health science fields in Ethiopia that were accessed through PubMed, PsycINFO, EMBASE, CINAHL databases and additional manual searching. SR and MA based on primary human studies associated with the Ethiopian population, irrespective of the place of publication and authors’ affiliation, and published until March 16, 2021, were included. Title/abstract and full-text screening were conducted in duplicate using EndNote and Covidence semi-automated reference management tools. Data extraction tool was developed using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and second version of A Measurement Tool to Assess Systematic Reviews (AMSTAR-2) guides. We summarized the data using frequencies and median. Two-tailed Chi-Square and Fisher’s Exact tests for categorical variables were used while Kruskal-Wallis test for quantitative variables at alpha level 0.05 to compare the differences in the background characteristics of SR and MA as well as across the publication years. All analyses were done using R version 4.0.2 for macOS. Of the total 3,125 records initially identified, 349 articles were included in our analyses. Of these, 48 (13.75%) were SR and 301 (86.25%) were MA. The publication rate was dramatically increased with nearly three-quarters (73.9%) of SR and MA published after 2018. Most of the SR and MA included observational studies (92.8%), and infectious disease was the most researched (20.9%) subject area. Number of authors, number of affiliations, publication year, protocol registration, number of primary studies, number of references, citation counts and journal quality were significantly different between SR and MA (p 0.05). Both SR and MA had a low methodological and reporting quality even though there were improvements in registering protocols, searching databases, and transparently reporting search strategy. The production of SR and MA in Ethiopia has been increased over time, especially during the last three years. There is a promising trend of improvement in methodological and reporting quality even though there is much more to do. This study provides an up-to-date overview of the landscape of SR and MA publication rate and quality leverage in Ethiopia. Authors should equally prioritize quality in addition to the fast-track publication.
Publisher: Informa UK Limited
Date: 05-2021
DOI: 10.2147/VHRM.S297403
Publisher: Cold Spring Harbor Laboratory
Date: 05-09-2018
DOI: 10.1101/405605
Abstract: The aim of this systematic review and meta-analysis was to investigate the association of gender of new-born, antenatal care (ANC) and postnatal care (PNC) with timely initiation of breastfeeding (TIBF) and exclusive breastfeeding (EBF) practice in Ethiopia. Systematic review and meta-analysis PubMed, EMBASE, CINAHL, WHO Global Health Library, Web of Science and SCOPUS databases systematically searched and complemented by manual searches to retrieve all available literature. Newcastle-Ottawa Scale (NOS) was used for quality assessment of included studies. Egger’s regression test at p-value threshold ≤ 0.01 was used to examine publication bias. Cochran’s Q X 2 test, τ 2 , and I 2 statistics were used to test heterogeneity, estimate amount of total/residual heterogeneity and measure variability attributed to heterogeneity respectively. A meta-analysis using a weighted inverse variance random-effects model was performed. The trend of evidence over time was evaluated by performing a cumulative meta-analysis. Furthermore, mixed-effects meta-regression analysis was done to identify possible sources of heterogeneity. Of 523 articles retrieved, 17 studies (N = 26,146 mothers) on TIBF and 27 studies (N = 17,819 mothers) on EBF were included in the final analysis. ANC (OR = 2.24, 95% CI 1.65 -3.04, p .001, I 2 = 90.9%), PNC (OR = 1.86, 95% CI 1.41 - 2.47, p .001, I 2 = 63.4%) and gender of new-born (OR = 1.31, 95% CI 1.01 - 1.68, p = 0.04, I 2 = 81.7%) significantly associated with EBF. In addition, ANC (OR = 1.70, 95% CI 1.10 - 2.65, p = 0.02, I 2 = 93.1%) was significantly associated with TIBF but not gender of new-born (OR = 1.02, 95% CI 0.86 -1.21, p = 0.82, I 2 = 66.2%). In line with our hypothesis, gender of new-born, ANC and PNC significantly associated with EBF. Likewise, ANC significantly associated with TIBF. Optimal care during pregnancy and after birth is important to ensure adequate breastfeeding. This meta-analysis study provided evidence on breastfeeding practices and its associated factors in Ethiopian context, which can be useful for cross-country and cross-cultural comparison and for breastfeeding improvement initiative in Ethiopia. CRD42017056768 and 10.1136/BMJOPEN-2017-017437 This systematic review and meta-analysis was conducted based on the registered and published protocol. Since it is the first study in Ethiopia, the information could be helpful for future researchers, public health practitioners, and healthcare policymakers. Almost all included studies were observational which may hinder causality inference. Perhaps the results may not be nationally representative given that studies from some regions are lacking. Based on the conventional methods of the heterogeneity test, a few analyses suffer from high between-study variation.
Publisher: BMJ
Date: 05-2018
Publisher: BMJ
Date: 08-2017
DOI: 10.1136/BMJOPEN-2017-017437
Abstract: Infant and young child feeding (IYCF) is the cornerstone of infant and child survival, healthy growth and development, healthy future generations and national development. In spite of the importance of optimal nutrition in low- and middle-income countries, there has been no review conducted in Ethiopia. Thus, the aim of this systematic review and meta-analysis is to estimate the national coverage and identify the associated factors of IYCF practices in Ethiopia. PubMed, Scopus, EMBASE, CINHAL, EBSCO, Web of Science and WHO Global Health Library databases will be searched for all available publications from 1 January 2000 to 30 September 2017. All published studies on the timely initiation of breast feeding, exclusive breast feeding and timely initiation of complementary feeding practice in Ethiopia will be screened, selected and reviewed. Bibliographies of identified articles and grey literature will be hand-searched as well. Heterogeneity of studies will be quantified using Higgins's method where I 2 statistic % indicates substantial heterogeneity. Funnel plots and Egger's regression test will be used to assess potential publication bias. The Newcastle–Ottawa Scale (NOS) will be used to assess the quality of evidence and risk of bias. Meta-analysis and meta-regression will be carried out to estimate the pooled national prevalence rate and an OR of each associated factor of IYCF practices. Narrative synthesis will be performed if meta-analysis is not feasible due to the substantial heterogeneity of studies. Ethical clearance is not required for this study because primary data will not be collected. The results of this systematic review and meta-analysis will be published in a peer-reviewed journal and presented at an (inter)national research symposium. This systematic review and meta-analysis has been registered with the International Prospective Register of Systematic Reviews (PROSPERO), registration number CRD42017056768.
Publisher: Pan African Medical Journal
Date: 2019
Publisher: BMJ
Date: 05-2019
DOI: 10.1136/BMJOPEN-2018-023956
Abstract: The aim of this systematic review and meta-analysis was to investigate the association of gender of newborn, antenatal care (ANC) and postnatal care (PNC) with timely initiation of breast feeding (TIBF) and exclusive breastfeeding (EBF) practices in Ethiopia. Systematic review and meta-analysis. To retrieve all available literature, PubMed, EMBASE, CINAHL, WHO Global Health Library, Web of Science and SCOPUS databases were systematically searched and complemented by manual searches. The search was done from August 2017 to September 2018. All observational studies including cross-sectional, case-control, cohort studies conducted in Ethiopia from 2000 to 2018 were included. Newcastle-Ottawa Scale was used for quality assessment of included studies. Study area, design, population, number of mothers (calculated s le size and participated in the study) and observed frequency data were extracted using Joanna Briggs Institute tool. To obtain the pooled effect size, a meta-analysis using weighted inverse variance random-effects model was performed. Cochran’s Q X 2 test, τ 2 and I 2 statistics were used to test heterogeneity, estimate amount of total/residual heterogeneity and measure variability attributed to heterogeneity, respectively. Mixed-effects meta-regression analysis was done to identify possible sources of heterogeneity. Egger’s regression test at p value threshold ≤0.01 was used to examine publication bias. Furthermore, the trend of evidence over time was examined by performing a cumulative meta-analysis. Of 523 articles retrieved, 17 studies (n=26 146 mothers) on TIBF and 24 studies (n=17 819 mothers) on EBF were included in the final analysis. ANC (OR=2.24, 95% CI 1.65 to 3.04, p .001, I 2 =90.9%), PNC (OR=1.86, 95% CI 1.41 to 2.47, p .001, I 2 =63.4%) and gender of newborn (OR=1.31, 95% CI 1.01 to 1.68, p=0.04, I 2 =81.7%) significantly associated with EBF. ANC (OR=1.70, 95% CI 1.10 to 2.65, p=0.02, I 2 =93.1%) was also significantly associated with TIBF but not with gender of newborn (OR=1.02, 95% CI 0.86 to 1.21, p=0.82, I 2 =66.2%). In line with our hypothesis, gender of newborn, ANC and PNC were significantly associated with EBF. Likewise, ANC was significantly associated with TIBF. Optimal care during pregnancy and after birth is important to ensure adequate breast feeding. This meta-analysis study provided up-to-date evidence on breastfeeding practices and its associated factors, which could be useful for breastfeeding improvement initiative in Ethiopia and cross-country and cross-cultural comparison. CRD42017056768
Publisher: Research Square Platform LLC
Date: 06-06-2023
DOI: 10.21203/RS.3.RS-2919591/V1
Abstract: Background Despite the rise in the number of systematic reviews (SR) and meta-analyses (MA) in medicine and health science fields in Ethiopia, there is limited up-to-date evidence on their methodological and reporting quality for using them in decision-making. The aim of this study was to characterize epidemiological trends and evaluate the methodological and reporting quality of SR and MA in Ethiopia. Methods A retrospective observational overview study was conducted on SR and MA in medicine and health science fields in Ethiopia that were accessed through PubMed, PsycINFO, EMBASE, CINAHL databases and additional manual searching. Title/abstract and full-text screening were conducted in duplicate using EndNote and Covidence semi-automated reference management tools. Data extraction tool was developed in consultation with standard guidelines. We summarized the data using frequencies and median. Two-tailed Chi-Square and Fisher’s Exact tests for categorical variables, while Kruskal-Wallis test for quantitative variables, were used at alpha level 0.05 to compare the differences in the background characteristics of SR and MA as well as across the publication years. All analyses were done using R version 4.0.2 for macOS. Results Of the total 3,125 records initially identified, 349 articles were included in our analyses. Of these, 48 (13.75%) were SR and 301 (86.25%) were MA. The publication rate was dramatically increased with nearly three-quarters (73.9%) of SR and MA published after 2018. Most of the SR and MA included observational studies (92.8%), and infectious disease was the most researched (20.9%) subject area. Number of authors, number of affiliations, publication year, protocol registration, number of primary studies, number of references, citation counts and journal quality were significantly different between SR and MA (p 0.05). Both SR and MA had a low methodological and reporting quality even though there were improvements in registering protocols, searching databases, and transparently reporting search strategy. Conclusions The production of SR and MA in Ethiopia has been increased over time, especially during the last three years. There is a promising trend of improvement in methodological and reporting quality even though there is much more to do. Authors should equally prioritize quality in addition to the fast-track publication.
Publisher: BMJ
Date: 2020
Publisher: Hindawi Limited
Date: 2015
DOI: 10.1155/2015/184902
Abstract: Background. The emotional consequences of diabetes have been scrutinized by a number of investigative teams and there are varying reports about the association of depression with type 2 diabetes mellitus. However, there is limited data about this in Ethiopia. Therefore, the purpose of this study was to assess the prevalence of comorbid depression among type 2 diabetic outpatients. Methods and Materials. Institution based cross-sectional study design was conducted on a random s le of 276 type 2 diabetic outpatients from Black Lion General Specialized Hospital. Systematic random s ling technique was used to get these in idual patients from 920 type 2 diabetic outpatients who have an appointment during the data collection period. Patients’ depression status was measured using Patient Health Questionnaire 9 (PHQ 9). Result. Totally 264 type 2 diabetic outpatients were interviewed with a response rate of 95.6%. The prevalence of depression among type 2 diabetic outpatients was 13%. Based on PHQ 9 score, 28.4% (75) fulfilled the criteria for mild depression, 12.1% (32) for moderate depression, 2.7% (7) for moderately severe depression, and 1.5% (4) for severe depression. But 45.8% (121) of patients had no clinically significant depression. Conclusion. This study demonstrated that depression is a common comorbid health problem in type 2 diabetic outpatients with a prevalence rate of 13%.
Publisher: Informa UK Limited
Date: 2021
DOI: 10.2147/JMDH.S293323
Publisher: Cold Spring Harbor Laboratory
Date: 25-02-2022
DOI: 10.1101/2022.02.24.22271416
Abstract: Although the publication of systematic reviews (SR) and meta-analyses (MA) has substantially grown in Ethiopia, no robust study systematically characterized these SR and MA was conducted. Thus, we aimed to map publication outputs, collaboration networks, research hotspots, and most cited SR and MA of medicine and health sciences in Ethiopia. We conducted a bibliometric study of SR and MA published up to December 31, 2021, and systematically searched via PubMed, PsycInfo, EMBASE, and Web of Science databases. We included all SR and MA in medicine and health sciences fields in Ethiopia irrespective of the authors’ affiliation and place of publication. Full records and cited references’ meta-data were extracted from the Web of Science Core Collection database. VOSviewer software was used to perform bibliometric analyses. The relevance of an item (e.g. author, country, or keywords) was measured by its weight based on frequencies using the full or binary counting method) and strength of the link between items was measured using total link strength. In total, 422 SR and MA were published between 2001 and 2021 by 14 research groups (i.e. overall, 1,066 authors participated) who affiliated with institutions from 33 countries. The largest number of SR and MA were published by authors affiliated with Debre Markos University, University of Gondar and Bahir Dar University. In addition, strong collaboration was observed among authors affiliated with institutions in Ethiopia, the Netherlands, Australia, and Canada. The identified research hotspots were maternal and child health, depression and substance use, cardiometabolic diseases, infectious diseases, HIV/AIDS, hepatitis and nutrition. The most cited SR was about domestic violence against women published in 2015. The SR and MA were published in 160 journals, with a majority published in PLOS (11%) and BMC (25%) journals. In this study, we provide a comprehensive summary of collaboration networks, research hotspots, and most cited SR and MA to gain a deeper understanding of the landscape of SR and MA research in Ethiopia. We believe that our study informs researchers, higher institutions, and policymakers about research hotspots and gaps in medicine and health sciences research in Ethiopia. The national and international collaboration is promising, and a concerted effort among researchers, policymakers and funding agencies could increase research outputs and broaden research areas.
Publisher: Public Library of Science (PLoS)
Date: 18-05-2021
DOI: 10.1371/JOURNAL.PONE.0250444
Abstract: Novel coronavirus-2019 (COVID-19) is a highly infectious disease that has caused a global pandemic. As of July 2020, there were 8,475 confirmed cases of COVID-19 in Ethiopia, and a total of 52 cases and 1 death were reported in Debre Berhan where this study was conducted. Under these conditions, we sought to assess what undergraduate students at Debre Berhan University knew about COVID-19 and how it shaped their attitudes and practices regarding this disease. The aim of the current study was to assess undergraduate student knowledge, attitudes and practices towards COVID-19 in Debre Berhan University, Ethiopia. A cross-sectional survey was conducted from March 18–24, 2020 among undergraduate students at Debre Berhan University. A two-stage cluster s ling technique was employed with a total s le size of 634. Proportional allocation of s les was used to the randomly selected colleges, and a systematic random s ling technique was employed to recruit the students. The data were checked for completeness, coded, entered into Epi-Data VS 3.1, and then exported into STATA™ Version 14 software for analysis. Descriptive statistics were conducted. Binary logistic regression analyses were used to identify factors. Factors were selected with the entry method. Adjusted odds ratios (AORs) and their 95% confidence intervals (CIs) were used to assess the associations between variables and knowledge, attitude and practices (KAP). From a total of 546 included participants, more than half of them, 307 (57%) were males. Seventy-three percent of them heard about novel coronavirus from social media. In this study, 73.8% of the participants were knowledgeable, and their overall attitude was favorable. Approximately 71.4% correctly responded that the main clinical symptoms of COVID-19 are fever, fatigue, dry cough, and shortness of breath. Nearly half, 229 (42%) of the students approved that they had no concern of being infected with COVID-19. Moreover, most participants showed poor practices more than half of the study subjects were not maintaining a physical distance. In multivariable analyses, people older than 25 years (AOR = 1.6, 95% CI 1.2, 4.6) and those who lived in urban areas (AOR = 4.3, 95% CI 2.6, 15.8) were significantly more knowledgeable about COVID-19. Furthermore, those students that have information about COVID-19 (AOR = 2.3, 95% CI 1.6, 8.7) was significantly associated with the attitude undergraduate students had about COVID-19 as compared with its counterpart. The undergraduate students at Debre Berhan University were moderately knowledgeable about COVID-19 and had an optimistic attitude towards its resolution. However, this optimism may lead to poor public health practices within this community. Therefore, greater efforts need to be made through more comprehensive and directed actions and awareness c aigns to increase the knowledge, attitude and practice of the students.
Publisher: Elsevier BV
Date: 06-2021
Publisher: Public Library of Science (PLoS)
Date: 02-08-2021
DOI: 10.1371/JOURNAL.PONE.0255613
Abstract: Short inter-pregnancy interval is an interval of months between the dates of birth of the preceding child and the conception date of the current pregnancy. Despite its direct effects on the perinatal and maternal outcomes, there is a paucity of evidence on its prevalence and determinant factors, particularly in Ethiopia. Therefore, this study assessed the prevalence and associated factors of short inter-pregnancy interval among pregnant women in Debre Berhan town, Northern Ethiopia. A community based cross-sectional study was conducted among a randomly selected 496 pregnant women in Debre Berhan town from February 9 to March 9, 2020. The data were collected by using an interviewer-administered questionnaire and analyzed using STATA (14.2) statistical software. To identify the predictors of short inter-pregnancy interval, multivariable binary logistic regression was fitted and findings are presented using adjusted odds ratio (AOR) with 95% confidence interval (CI). The overall prevalence of short inter-pregnancy interval ( months) among pregnant women was 205 (40.9%). Being over 30 years of age at first birth (AOR = 3.50 95% CI: 2.12–6.01), non-use of modern contraceptive (AOR = 2.51 95% CI: 1.23–3.71), duration of breastfeeding for less than 12 months (AOR = 2.62 95% CI: 1.32–5.23), parity above four (AOR = 0.31 95% CI: 0.05–0.81), and unintended pregnancy (AOR = 5.42 95% CI: 3.34–9.22) were independently associated factors with short inter-pregnancy interval. Despite the public health interventions being tried in the country, the prevalence of short inter-pregnancy interval in this study is high. Therefore, it implies that increasing contraceptive use and encouraging optimal breastfeeding might help in the efforts made to avert the problem.
No related grants have been discovered for Nigussie Tadesse Sharew.