ORCID Profile
0000-0003-1968-1988
Current Organisation
The University of New South Wales, Australia
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Research Topics
In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Top 5 Research Topics
ANZSRC Field of Research (FoR)
Geochemistry | Palaeoclimatology | Quaternary Environments | Geology | Geochronology And Isotope Geochemistry | Geomorphology and Regolith and Landscape Evolution | Archaeological Science | Marine Geoscience | Climatology (Incl. Palaeoclimatology) | Isotope Geochemistry
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Earth Sciences | Climate variability | Oil and Gas Exploration | Effects of Climate Change and Variability on Australia (excl. Social Impacts) | Forest and Woodlands Soils | Physical and Chemical Conditions of Water in Fresh, Ground and Surface Water Environments (excl. Urban and Industrial Use) | Earth sciences |
Related Links
Publications
A feasibility study to inform the design of a randomised controlled trial to identify the most clinically effective and cost-effective length of Anticoagulation with Low-molecular-weight heparin In th
Publisher: National Institute for Health and Care Research
Date: 10-2015
DOI: 10.3310/HTA19830
Abstract: Venous thromboembolism is common in cancer patients and requires anticoagulation with low-molecular-weight heparin (LMWH). Current data recommend LMWH for anticoagulation as far as 6 months, yet guidelines recommend LMWH beyond 6 months in patients who have ongoing or active cancer. This recommendation, based on expert consensus, has not been evaluated in a clinical study. (1) To identify the most clinically and cost-effective length of anticoagulation with LMWH in the treatment of cancer-associated thrombosis (CAT) (2) to identify practicalities of conducting a full randomised controlled trial (RCT) with regard to recruitment, retention and outcome measurement and (3) to explore the barriers for progressing to a full RCT. The Anticoagulation with Low-molecular-weight heparin In the treatment of Cancer-Associated Thrombosis (ALICAT) trial is a randomised, multicentre, feasibility mixed-methods study with three components: (1) a RCT comparing ongoing LMWH treatment for CAT with cessation of LMWH at 6 months’ treatment (current licensed practice) in patients with locally advanced or metastatic cancer, consulted in three clinical settings (haematology outpatients, oncology outpatients and primary care) (2) a nested qualitative study, including focus groups with clinicians to investigate attitudes for recruiting to the study and identify the challenges of progressing to a full RCT, and semistructured interviews with patients and relatives to explore their attitudes towards participating in the study, and potential barriers and concerns to participation and (3) a UK-wide survey exercise to develop a classification and enumeration system for the CAT models and pathways of care. A haematology outpatients department, an oncology outpatients department and primary care. Patients with ongoing active or metastatic cancer who have received 6 months of LMWH for CAT. Ongoing LMWH treatment for CAT versus cessation of LMWH at 6 months’ treatment in patients with locally advanced or metastatic cancer. (i) The number of eligible patients over 12 months (ii) the number of recruited patients over 12 months (target recruitment rate of 30% of eligible patients) and (iii) the proportion of randomised participants with recurrent venous thromboembolisms (VTEs) during follow-up. Following several delays in setting up the RCT component of the study, 5 out of 32 eligible patients consented to be randomised to the RCT suggesting progression to a full RCT was not feasible. Reasons for non-consenting were primarily based on a fixed preference for continuing or discontinuing treatment after 6 months of anticoagulation, and a fear of randomisation to their non-preferred option. Views were largely influenced by patients’ initial experience of CAT. Focus groups with clinicians revealed that they would be reticent to recruit to such a study as they had fixed views of best management despite the lack of evidence. Patient pathway modelling suggested that there is a broad heterogeneity of practice with respect to CAT management and co-ordination, with no consensus on which specialty should best manage such cases. The results of the RCT reflect recruitment from the oncology site only and provide no recruitment data from haematology centres. However, it is unlikely that these other sites would have access to more eligible patients. The management of cancer-associated thrombosis beyond 6 months will remain a clinical challenge. As it is unlikely that a prospective study will successfully recruit, other strategies to accrue relevant data are necessary. Currently the LONGHEVA (Long-term treatment for cancer patients with deep-venous thrombosis or pulmonary embolism) registry is in development to prospectively evaluate this important and common clinical scenario. This study is registered as clinical trials.gov number NCT01817257 and International Standard Randomised Controlled Trial Number (ISRCTN) 37913976. Funding for the ALICAT trial was provided by the Health Technology Assessment programme (10/145/01) in response to a themed funding call. The study was designed in accordance with the initial funding brief and feedback from the review process.
Fluid inclusion and stable isotope study of the Esfordi apatite-magnetite deposit, central Iran
Publisher: Society of Economic Geologists
Date: 09-2007
Geochemical effects of deeply buried Cu Au mineralization on transported regolith in an arid terrain
Publisher: Geological Society of London
Date: 21-07-2009
Land use influences on soil geochemistry in Lefkosia (Nicosia) Cyprus
Publisher: Elsevier BV
Date: 04-2016
Modelling soil salinity across a gilgai landscape by inversion of EM38 and EM31 data
Publisher: Wiley
Date: 23-06-2015
DOI: 10.1111/EJSS.12278
Quantitative chemical profiling of coal using core-scanning X-ray fluorescence techniques
Publisher: Elsevier BV
Date: 08-2014
Geochemical patterns in the soils of Cyprus
Publisher: Elsevier BV
Date: 03-2012
DOI: 10.1016/J.SCITOTENV.2012.01.036
Abstract: The soil geochemical atlas of Cyprus is a recent addition to the series of national to continental-scale geochemical mapping programmes implemented over the last two decades for environmental and resource applications. The study has been conducted at the high s ling density of 1 site per 1km(2), with multi-element and multi-method analysis performed on s les of top soil (0-25cm) and sub soil (50-75cm) from a grid of over 5350 sites across a major portion of Cyprus. Major and most trace elements display sharp concentration changes across the main geological boundaries but a high degree of spatial continuity and consistency of values within those boundaries. Some elements display one to two orders of magnitude difference in median concentrations between the soils developed over ultramafic or mafic units and those developed over sedimentary rocks or alluvial units. The ratio of aqua regia-extractable to total metal contents provides an indication of the general mineralogical host for a number of trace elements. The majority of soils are near-neutral to alkaline with the small proportion of areas with soil pH<5 largely restricted to the major Cu deposits. There is strong correlation between top soil and sub soil geochemical values. Where the concentrations of some elements (including Pb, Hg and Sn) are indicative of contamination, the values are typically higher in the top soil s les in these areas. Variations in the concentration of elements with strong redox controls on mobility are linked to changes in sedimentary environment between deep and shallow marine conditions. Some element patterns can be related to the effects of urbanisation and sulphide mining operations however the dominant control on soil geochemistry is the parent geology and regolith forming processes. The atlas demonstrates the effectiveness of high-density s ling in mapping local to regional-scale features of the geochemical landscape.
A new type of synthetic geochemical reference material - SynTERM
Publisher: Royal Society of Chemistry (RSC)
Date: 1995
DOI: 10.1039/AN9952001327
Interaction of aqueous Au species with goethite, smectite and kaolinite
Publisher: Geological Society of London
Date: 08-2004
Biogeochemistry: A geochemical method for gold exploration in the Canadian Shield
Publisher: Elsevier BV
Date: 1987
A comparison of fractal methods and probability plots in identifying and mapping soil metal contamination near an active mining area, Iran
Publisher: Elsevier BV
Date: 10-2013
DOI: 10.1016/J.SCITOTENV.2013.06.100
Abstract: Mining activities may contribute significant amounts of metals to surrounding soils. Assessing the potential effects and extent of metal contamination requires the differentiation between geogenic and additional anthropogenic sources. This study compares the use of conventional probability plots with two forms of fractal analysis (number-size and concentration-area) to separate geochemical populations of ore-related elements in agricultural area soils adjacent to Pb-Zn mining operations in the Irankuh Mountains, central Iran. The two general approaches deliver similar spatial groupings of univariate geochemical populations, but the fractal methods provide more distinct separation between populations and require less data manipulation and modeling than the probability plots. The concentration-area fractal approach was more effective than the number-size fractal and probability plotting methods at separating sub-populations within the s les affected by contamination from the mining operations. There is a general lack of association between major elements and ore-related metals in the soils. The background populations display higher relative variation in the major elements than the ore-related metals whereas near the mining operations there is far greater relative variation in the ore-related metals. The extent of the transport of contaminants away from the mine site is partly a function of the greater dispersion of Zn compared with Pb and As, however, the patterns indicate dispersion of contaminants from the mine site is via dust and not surface/groundwater. A combination of geochemical and graphical assessment, with different methods of threshold determination, is shown to be effective in separating geogenic and anthropogenic geochemical patterns.
The regional geochemical baseline soil survey of southern New Zealand: Design and initial interpretation
Publisher: Elsevier BV
Date: 08-2016
Siderophore‐Assisted Dissolution of Iron(III) Hydroxide Oxides from Iron‐Rich Fossil Matrices
Publisher: Wiley
Date: 08-2020
Optimization of partial extraction chemistry for buffered acetate and hydroxylamine leaches
Publisher: Geological Society of London
Date: 08-2005
Geochemical Prospectivity Mapping Through a Feature Extraction–Selection Classification Scheme
Publisher: Springer Science and Business Media LLC
Date: 26-10-2018
A comparison of unsupervised neural networks and k-means clustering in the analysis of multi-element stream sediment data
Publisher: Geological Society of London
Date: 05-2001
Abstract: Isolation of complex patterns of correlation between variables, association among s les and anomaly identification, through conventional parametric multivariate statistical procedures, may be obscured by the presence of multivariate outliers and non-normal variable distributions. Procedures such as k-means clustering generally require substantial data pre-processing. Unsupervised neural networks (UNN) have the capacity to cluster multivariate data, using a modified form of the standard unsupervised Kohonen self-organizing map that is non-linear, non-parametric, rapid and robust. The number of clusters into which s les are allocated is determined by the unsupervised neural network and is directly dependent upon the original input data. UNN and k-means clustering was performed on stream sediment geochemical data from 1670 sub-catchments in the northeast region of New South Wales. Both methods produced clusters for the feldspar-associated elements that were closely related to sub-catchment geology and topography. UNN clustering revealed more subtle variations within the major lithological groups. UNN clustering of Cu–Pb–Zn produced ten main clusters and identified 26 anomalies, that were mainly from sub-catchments, containing significant base metal mineralization occurrences. K-means clustering of transformed Cu–Pb–Zn yielded five major clusters and only 19 anomalies. Progressive increase in k from eight to 20 did not substantially alter the k-means classification of s les between common groups and anomalies. Some catchments identified only as anomalous by UNN clustering contain known base metal mineralization.
Calibration for ED-XRF profiling of coal cores for the Itrax Core Scanner
Publisher: Cambridge University Press (CUP)
Date: 20-10-2014
DOI: 10.1017/S088571561400089X
Abstract: Recent developments in instrumentation mean that chemical analysis of large drill cores taken for geological purposes can be performed rapidly at sub-millimetre scales using core scanners equipped with energy-dispersive X-ray fluorescence spectrometers. The present study describes the development of a calibration for the Itrax Core Scanner (Cox Analytical, Sweden), intended for whole cores of coal-seam sections, without the need for s le preparation. The calibration was developed for key major elements (Al, Si, P, S, K, Ca, Ti, and Fe) based on pressed pellets of reference coals, allowing semi-quantitative and, at times, quantitative analyses. The influence of core curvature and surface roughness compared with an ideal flat-surface was also examined using model s les, and their influence on the apparent s le composition evaluated.
Stability and trace element composition of natural schwertmannite precipitated from acid mine drainage
Publisher: Elsevier BV
Date: 08-2022
Fluid inclusion and stable isotope study of the esfordi apatite-magnetite deposit, central Iran - A reply
Publisher: Society of Economic Geologists
Date: 2009
Geochemical pattern recognition through matrix decomposition
Publisher: Elsevier BV
Date: 2019
Major advances in exploration geochemistry, 1998-2007
Publisher: Geological Society of London
Date: 02-2010
Reflections of the geological characteristics of Cyprus in soil rare earth element patterns
Publisher: Elsevier BV
Date: 05-2015
A comparison of selective extraction soil geochemistry and biogeochemistry in the Cobar area, New South Wales
Publisher: Elsevier BV
Date: 05-1998
Metal speciation in agricultural soils adjacent to the Irankuh Pb-Zn mining area, central Iran
Publisher: Elsevier BV
Date: 2015
Correction to: Geochemical Prospectivity Mapping Through a Feature Extraction–Selection Classification Scheme
Publisher: Springer Science and Business Media LLC
Date: 04-12-2018
Distribution of water-soluble inorganic ions in the soils of Cyprus
Publisher: Elsevier BV
Date: 11-2014
Biogeochemical mapping of metal contamination from mine tailings using field-portable XRF
Publisher: Elsevier BV
Date: 04-2019
DOI: 10.1016/J.SCITOTENV.2019.01.235
Abstract: Trace and major element composition of selected plant species and parts may be used to map geochemical dispersion from mineral deposits and contaminated areas. This study examines the application of field-portable X-ray fluorescence spectrometry (fpXRF) in obtaining real-time biogeochemical data. In situ analysis of parts of black and silver wattle (Acacia mearnsii De Wild. and Acacia dealbata Link) was conducted to map the extent of contamination surrounding the former Woodlawn base metal mine. High levels of ore-related elements were detected in the bark of these species in a zone extending up to 1 km down-drainage from the tailing ponds. Major elements are more elevated in bark on the side of the trees facing the tailings ponds and correlations between trace and major elements indicate dust contamination. The penetration distance for X-rays is dependent on the energy of the secondary X-rays measured, with the maximum depth of penetration in bark and leaf material <30 mm. There was a close correlation for most elements between the fpXRF and laboratory-based XRF analysis but with element-dependent attenuation by the organic matrix. Providing there is consistency in s ling and analytical methodology, in situ fpXRF analysis of vegetation is an effective method in both contamination surveys and biogeochemical mineral exploration for a range of trace and major elements.
Concentration-distance from centroids (C-DC) multifractal modeling: A novel approach to characterizing geochemical patterns based on sample distance from mineralization
Publisher: Elsevier BV
Date: 10-2021
Identification of potential for methane ignition by rock friction in Australian coal mines
Publisher: Elsevier BV
Date: 2001
Mineral distribution and provenance of heavy mineral sands (zircon, ilmenite, rutile) deposits from the NW Murray Basin, far western NSW, Australia
Publisher: Informa UK Limited
Date: 30-01-2020
Contrasting dispersion patterns for gold in stream sediments at Timbarra, NSW, Australia
Publisher: Elsevier BV
Date: 2005
Application of singular value decomposition (SVD) and semi-discrete decomposition (SDD) techniques in clustering of geochemical data: an environmental study in central Iran
Publisher: Springer Science and Business Media LLC
Date: 23-01-2016
Exploration Geochemistry
Publisher: Elsevier
Date: 2013
Anthropogenic versus lithological influences on soil geochemical patterns in Cyprus
Publisher: Geological Society of London
Date: 11-2012
Fractally invariant distributions and an application in geochemical exploration
Publisher: Springer Science and Business Media LLC
Date: 11-2005
Comparison of vegetation and stream sediment geochemical patterns in northeastern New South Wales
Publisher: Elsevier BV
Date: 09-1999
Related Organisations
Related Funding Activities
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100067
Start Date: 2016
End Date: 12-2020
Amount: $10,000,000.00
Funder: Australian Research Council
View Funded ActivityLinkage Infrastructure, Equipment And Facilities - Grant ID: LE0989067
Start Date: 2009
End Date: 06-2010
Amount: $950,000.00
Funder: Australian Research Council
View Funded ActivityLinkage Infrastructure, Equipment And Facilities - Grant ID: LE140100023
Start Date: 2014
End Date: 12-2014
Amount: $360,000.00
Funder: Australian Research Council
View Funded Activity