ORCID Profile
0000-0003-0292-9983
Current Organisations
UNSW Sydney
,
La Trobe University
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In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Philosophy | Human Bioethics | Applied Ethics | Law And Society | Nanotechnology | Macromolecular and Materials Chemistry | Synthesis of Materials | Biomaterials | Language In Culture And Society (Sociolinguistics) | Electrochemistry | Physical Chemistry (Incl. Structural) | Applied Ethics (Incl. Bioethics And Environmental Ethics) | Nanomanufacturing | Bioethics (human and animal) | Functional Materials | Ethical Theory | Feminist Theory | Sociology | Sociology not elsewhere classified | Public Health and Health Services not elsewhere classified | Social Philosophy |
Social ethics | Civics and citizenship | Bioethics | Energy storage | Solar-photoelectric | Social Ethics | Health education and promotion | Bioethics | Medical instrumentation | Expanding Knowledge in Technology | Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Treatments (e.g. chemicals, antibiotics) | Social structure and health | Infectious Diseases
Publisher: Jenny Stanford Publishing
Date: 10-10-2019
Publisher: Informa UK Limited
Date: 02-1998
Publisher: Oxford University Press
Date: 12-05-2021
DOI: 10.1093/OXFORDHB/9780190628925.013.40
Abstract: This chapter focuses on feminist philosophical engagement with biomedical technologies, such as the development of in vitro fertilisation (IVF), genetic engineering, bionic implants, neural interventions, and synthetic biology. The chapter starts with a short account of the contemporaneous rise of bioethics as a subdiscipline of philosophy, a range of emerging biomedical technologies and the second wave of feminist political action and theory. It outlines some key feminist philosophical approaches to issues in biomedicine: including those focusing on autonomy and choice care and care work and the moral significance of narrative, embodiment and phenomenological experience. It ends by identifying some evolving future directions for feminist philosophical contributions to emerging technologies informed by discussion of vulnerability and dependence disability, neural ersity, and human enhancement.
Publisher: Springer Science and Business Media LLC
Date: 08-2005
DOI: 10.1007/BF02448848
Publisher: Informa UK Limited
Date: 06-1998
Publisher: Wiley
Date: 30-05-2013
DOI: 10.1111/BIOE.12032
Abstract: Several foundational documents of bioethics mention the special obligation researchers have to vulnerable research participants. However, the treatment of vulnerability offered by these documents often relies on enumeration of vulnerable groups rather than an analysis of the features that make such groups vulnerable. Recent attempts in the scholarly literature to lend philosophical weight to the concept of vulnerability are offered by Luna and Hurst. Luna suggests that vulnerability is irreducibly contextual and that Institutional Review Boards (Research Ethics Committees) can only identify vulnerable participants by carefully examining the details of the proposed research. Hurst, in contrast, defines the vulnerable as those especially at risk of incurring the wrongs to which all research ethics participants are exposed. We offer a more substantive conception of vulnerability than Luna but one that gives rise to a different rubric of responsibilities from Hurst's. While we understand vulnerability to be an ontological condition of human existence, in the context of research ethics, we take the vulnerable to be research subjects who are especially prone to harm or exploitation. Our analysis rests on developing a typology of sources of vulnerability and showing how distinct sources generate distinct obligations on the part of the researcher. Our account emphasizes that the researcher's first obligation is not to make the research participant even more vulnerable than they already are. To illustrate our framework, we consider two cases: that of a vulnerable population involved in international research and that of a domestic population of people with diminished capacity.
Publisher: Springer International Publishing
Date: 2016
Publisher: Springer International Publishing
Date: 2016
Publisher: Springer US
Date: 2020
DOI: 10.1007/978-1-0716-0520-2_4
Abstract: 3D bioprinting involves engineering live cells into a 3D structure, using a 3D printer to print cells, often together with a compatible 3D scaffold. 3D-printed cells and tissues may be used for a range of purposes including medical research, in vitro drug testing, and in vivo transplantation. The inclusion of living cells and biomaterials in the 3D printing process raises ethical, policy, and regulatory issues at each stage of the bioprinting process that include the source of cells and materials, stability and biocompatibility of cells and materials, disposal of 3D-printed materials, intended use, and long-term effects. This chapter focuses on the ethical issues that arise from 3D bioprinting in the lab-from consideration of the source of cells and materials, ensuring their quality and safety, through to testing of bioprinted materials in animal and human trials. It also provides guidance on where to seek information concerning appropriate regulatory frameworks and guidelines, including on classification and patenting of 3D-bioprinted materials, and identifies regulatory gaps that deserve attention.
Publisher: Springer International Publishing
Date: 2016
Publisher: Elsevier BV
Date: 05-2023
Publisher: Springer International Publishing
Date: 2016
Publisher: Elsevier BV
Date: 06-2023
DOI: 10.1016/J.AJIC.2022.08.010
Abstract: Contact Precautions (CP) were developed to control multi-resistant organisms (MROs) in hospitals. However, MROs persist and harms are associated with CP. Research objectives were to understand the bioethical impact of CP on patients and health-professionals, and make recommendations for ethically-improved management of MRO-colonized patients. Interpretive description methodology scaffolded upon bioethical principles framed this qualitative study. Findings were explored alongside contemporary published reports to make recommendations for practice and research. Nine patients and 24 health professionals participated. Four themes were found: Powerlessness moving to acceptance You feel a bit of a pariah Others need protection, but I need looking after too Doing Contact Precautions is not easy. CP conflict with the principle of respect for autonomy due to non-adherence to informed consent, and sub-optimal communication. Patients experience health care inequality, and discriminatory practices breaching the principle of justice. CP elicit stigma for patients, and moral distress and inter-personal conflict for staff, breaching the principle of non-maleficence. Under the principle of beneficence, pluralistic cost-benefit assessment situates CP as low-value practice. CP challenge organizational culture, professional well-being, and person-centered ethical care. Ethical costs of CP outweigh benefits, obliging policy-makers to reconsider CP in managing MRO-colonized patients.
Publisher: Springer Science and Business Media LLC
Date: 04-2000
DOI: 10.1007/BF03351236
Publisher: Springer International Publishing
Date: 2016
Publisher: Oxford University Press
Date: 03-12-2013
Publisher: Springer International Publishing
Date: 2016
Publisher: Elsevier BV
Date: 03-2020
DOI: 10.1016/J.IDH.2019.12.006
Abstract: Nurses face challenges when providing information about multi-resistant organisms (MROs), and related hospital policies, to patients found to be colonised, and may be concerned for their own safety when caring for MRO-colonised people. Resultant emotional responses may influence behaviours of staff caring for these patients. This study aimed to identify the feelings experienced by nurses when talking about MROs with patients. Secondary objectives were to learn about staff behaviours towards MRO-colonised patients, and to explore the utility of Emotional Touchpoints methodology in this context. A qualitative study using an adapted Emotional Touchpoints method delivered as a paper survey tool for data collection. Content analysis and inductive coding of responses was used to identify key themes. 53 nurses participated. 'Nervous', 'Concerned' and 'Knowledgeable' were the most commonly selected adjectives chosen to describe their feelings. Reasons for these choices were themed as 'Empowerment through knowledge', 'Performance anxiety', 'Concern for the patient' and 'Concern for professional reputation'. Social or temporal distancing, and the need for staff and other patients to be protected from contagion were key themes for the behaviours these nurses had witnessed towards patients. Talking about MROs with patients can elicit strong emotional responses in nurses, and MRO-colonised patients may be treated and spoken about in a discriminatory fashion. Infection prevention and control teams should recognise this and focus on the person rather than the pathogen when educating and supporting nurses. Recommendations for practice are made to support improved wellbeing of nurses as well as MRO colonised patients.
Publisher: Oxford University Press
Date: 03-12-2013
Publisher: Wiley
Date: 11-2006
Publisher: Springer Science and Business Media LLC
Date: 07-2002
DOI: 10.1007/BF03351274
Publisher: Springer Science and Business Media LLC
Date: 07-2002
DOI: 10.1007/BF03351282
Publisher: Wiley
Date: 10-1988
Publisher: Wiley
Date: 1989
Publisher: Informa UK Limited
Date: 03-04-2015
Publisher: Springer Science and Business Media LLC
Date: 30-09-2008
DOI: 10.1007/S11948-008-9089-Y
Abstract: Despite the amount of public investment in nanotechnology ventures in the developed world, research shows that there is little public awareness about nanotechnology, and public knowledge is very limited. This is concerning given that nanotechnology has been heralded as 'revolutionising' the way we live. In this paper, we articulate why public engagement in debates about nanotechnology is important, drawing on literature on public engagement and science policy debate and deliberation about public policy development. We also explore the significance of timing in engaging the public, and we make some suggestions concerning how to effectively engage publics. Our conclusions indicate the significance of scientific researchers, policy makers and representative consumer groupings in public reasoning towards a better public policy framework for debate about technological development.
Publisher: BMJ
Date: 05-2005
Publisher: Routledge
Date: 24-06-2022
Publisher: University of Toronto Press Inc. (UTPress)
Date: 2015
Publisher: Wiley
Date: 21-10-2021
DOI: 10.1111/BIOE.12961
Abstract: The increasing dementia prevalence worldwide is driving the testing of novel therapeutic approaches, such as invasive brain technologies, despite limited clinical evidence and the risk of accelerating cognitive decline. Our manuscript (a) reviews the NIH Clinicaltrials.gov database for deep brain stimulation, stem cell implantation, and gene therapy trials on people with dementia (b) discusses issues on beneficence, nonmaleficence, and autonomy associated with these trials and (c) proposes nine recommendations that build on elements from the Declaration of Helsinki. We found 49 preregistered high‐risk trials from nine countries planning to or involving 11,801 people with Alzheimer's or Lewy body dementia or dementia secondary to Parkinson's or Huntington's disease. Most of the people with Alzheimer's who are in these trials are from North America and East Asia. There is substantial heterogeneity in the enrolment criteria, even for trials recruiting only those with Alzheimer's disease. Although most trials enrol people in mild to moderate stages of Alzheimer's disease, trials in China enrol people who have severe Alzheimer's. Our findings highlight a pressing need to review and refine the enrolment criteria for invasive neural trials in people with dementia, considering risks, potential benefits, and capacity for informed consent. As a multidisciplinary team from Australia, the USA, Canada, and Germany with expertise in neurology, neuroscience, and ethics, we examine how it is essential to balance the risks of invasive neural research in a vulnerable population with limited capacity to provide informed consent to help advance the body of knowledge regarding a disease with limited therapeutic options.
Publisher: Springer International Publishing
Date: 2016
Publisher: MDPI AG
Date: 07-02-2023
Abstract: Human brain organoids provide a remarkable opportunity to model prenatal human brain biology in vitro by recapitulating features of in utero molecular, cellular and systems biology. An ethical concern peculiar to human brain organoids is whether they are or could become capable of supporting sentience through the experience of pain or pleasure and/or consciousness, including higher cognitive abilities such as self-awareness. Identifying the presence of these traits is complicated by several factors, beginning with consciousness—which is a highly contested concept among neuroscientists, cognitive scientists, and philosophers and so there is no agreed definition. Secondly, given human brain organoids are disembodied, there is no practical way to identify evidence of consciousness as we might in humans or animals. What would count as evidence of organoid consciousness is an emerging area of research. To address concerns about consciousness and human brain organoids, in this paper we clarify the morally relevant aspects of human consciousness, phenomenal experience and embodied development and explore the empirical basis of consciousness to develop a defensible framework for informed decision-making on the moral significance and utility of brain organoids, which can also guide regulation and future research of these novel biological systems.
Publisher: University of Toronto Press Inc. (UTPress)
Date: 10-2008
Publisher: Elsevier BV
Date: 09-2021
Publisher: Philosophy Documentation Center
Date: 1988
Publisher: Humana Press
Publisher: Springer Science and Business Media LLC
Date: 15-07-2006
Publisher: Wiley
Date: 24-11-2018
DOI: 10.1111/BIOE.12414
Abstract: There has been a surge in mass media reports extolling the potential for using three-dimensional printing of biomaterials (3D bioprinting) to treat a wide range of clinical conditions. Given that mass media is recognized as one of the most important sources of health and medical information for the general public, especially prospective patients, we report and discuss the ethical consequences of coverage of 3D bioprinting in the media. First, we illustrate how positive mass media narratives of a similar biofabricated technology, namely the Macchiarini scaffold tracheas, which was involved in lethal experimental human trials, influenced potential patient perceptions. Second, we report and analyze the positively biased and enthusiastic portrayal of 3D bioprinting in mass media. Third, we examine the lack of regulation and absence of discussion about risks associated with bioprinting technology. Fourth, we explore how media misunderstanding is dangerously misleading the narrative about the technology.
Publisher: BMJ
Date: 06-1996
DOI: 10.1136/JME.22.3.160
Abstract: Despite moves to enhance the autonomy of clients of health care services, the use of a variety of physical restraints on the freedom of movement of frail, elderly patients continues in nursing homes. This paper confronts the use of restraints on two grounds. First, it challenges the assumption that use of restraints is necessary to protect the welfare of frail, elderly patients by drawing on a range of data indicating the limited efficacy of restraints. Secondly, it argues that the duty to respect in idual autonomy extends to a duty to respect the autonomy of patients who are elderly, frail and living in nursing homes.
Publisher: SAGE Publications
Date: 15-06-2017
Abstract: Hospital infection control practices known as Contact Precautions are recommended for the management of people with pathogens such as methicillin-resistant Staphylococcus aureus or vancomycin-resistant Enterococci. Background: The patient is isolated, and staff are required to wear gloves, and a gown or apron when providing care. A notice is displayed to remind staff of these requirements and an ‘alert’ message is placed in the patient’s medical record. Objective: The aim of this article is to discuss and explore whether practices used in hospitals to reduce the transmission of endemic antibiotic-resistant organisms are ethically justified in today’s healthcare environment in the developed world. In order to do this, the history of the development of these practices is summarised, and the evidence base for their effectiveness is reviewed. Key bioethics principles are then discussed and contextualised from the perspective of hospital infection prevention and control, and an ethically superior model for the prevention and control of healthcare associated infection is proposed.
Publisher: Springer Science and Business Media LLC
Date: 09-02-2018
DOI: 10.1007/S11948-017-9874-6
Abstract: Recent developments of three-dimensional printing of biomaterials (3D bioprinting) in medicine have been portrayed as demonstrating the potential to transform some medical treatments, including providing new responses to organ damage or organ failure. However, beyond the hype and before 3D bioprinted organs are ready to be transplanted into humans, several important ethical concerns and regulatory questions need to be addressed. This article starts by raising general ethical concerns associated with the use of bioprinting in medicine, then it focuses on more particular ethical issues related to experimental testing on humans, and the lack of current international regulatory directives to guide these experiments. Accordingly, this article (1) considers whether there is a limit as to what should be bioprinted in medicine (2) examines key risks of significant harm associated with testing 3D bioprinting for humans (3) investigates the clinical trial paradigm used to test 3D bioprinting (4) analyses ethical questions of irreversibility, loss of treatment opportunity and replicability (5) explores the current lack of a specific framework for the regulation and testing of 3D bioprinting treatments.
Publisher: Informa UK Limited
Date: 04-2013
Publisher: Wiley
Date: 11-2007
DOI: 10.1111/J.1467-8519.2007.00595.X
Abstract: People who are paid to provide basic care for others are frequently undervalued, exploited and expected to reach often unrealistic standards of care. I argue that appropriate social recognition, support and fair pay for people who provide care for those who are disabled, frail and aged, or suffering ill health that impedes their capacity to negotiate daily activities without support, depends on a reconsideration of the paradigm of the citizen or and moral agent. I argue that by drawing on the ideas of human vulnerability and dependency as central to our personhood, a more realistic conception of selves, citizens and persons can be developed that better recognises the inevitability of human dependency and the social value of care work. I also indicate the significance of this vulnerability-focussed view for ethical evaluation of the emotional aspects of care relationships.
Publisher: Informa UK Limited
Date: 09-2008
Publisher: Wiley
Date: 11-2007
Publisher: Oxford University Press
Date: 03-12-2013
Publisher: Springer Science and Business Media LLC
Date: 10-08-2013
Publisher: Oxford University Press
Date: 26-03-2020
DOI: 10.1093/OSO/9780190651145.003.0005
Abstract: The world’s first clinical trial using advisory brain implant operated by artificial intelligence (AI) has been completed with significant success. The tested devices predict a specific neuronal event (epileptic seizure), allowing people implanted with the device to be forewarned and to take steps to reduce or avoid the impact of the event. In principle, these kinds of artificially intelligent devices could be used to predict other neuronal events and allow those implanted with the device to take precautionary steps or to automate drug delivery so as to avoid unwanted outcomes. This chapter examines moral issues arising from the hypothetical situation where such devices controlled by AI are used to ensure that convicted criminal offenders are safe for release into society. We distinguish two types of predictive technologies controlled by AI: advisory systems and automated therapeutic response systems. The purpose of this chapter is to determine which of these two technologies would generate fewer ethical concerns. While there are moral similarities between the two technologies, the latter raises more concerns. In particular, it raises the possibility that in idual moral decision-making and moral autonomy can be threatened by the use of automated implants.
Start Date: 2014
End Date: 2020
Funder: Australian Research Council
View Funded ActivityStart Date: 2005
End Date: 2014
Funder: Australian Research Council
View Funded ActivityStart Date: 2004
End Date: 2004
Funder: Australian Research Council
View Funded ActivityStart Date: 2018
End Date: 2022
Funder: Australian Research Council
View Funded ActivityStart Date: 2005
End Date: 2008
Funder: Australian Research Council
View Funded ActivityStart Date: 2014
End Date: 2021
Funder: Australian Research Council
View Funded ActivityStart Date: 08-2018
End Date: 06-2022
Amount: $318,473.00
Funder: Australian Research Council
View Funded ActivityStart Date: 07-2005
End Date: 06-2014
Amount: $19,700,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 06-2014
End Date: 06-2021
Amount: $25,000,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2005
End Date: 03-2012
Amount: $339,658.00
Funder: Australian Research Council
View Funded ActivityStart Date: 09-2004
End Date: 11-2004
Amount: $10,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 01-2011
End Date: 06-2014
Amount: $250,000.00
Funder: Australian Research Council
View Funded Activity