ORCID Profile
0000-0002-9020-7018
Current Organisation
University of New South Wales
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In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Synthesis of Materials | Macromolecular and Materials Chemistry | Polymerisation Mechanisms | Chemical Engineering | Functional Materials | Chemical Engineering Design | Biomaterials | Polymers and Plastics
Expanding Knowledge in the Chemical Sciences | Polymeric Materials (e.g. Paints) | Expanding Knowledge in Technology | Expanding Knowledge in Engineering |
Publisher: American Chemical Society (ACS)
Date: 19-01-2023
DOI: 10.26434/CHEMRXIV-2023-4XT14
Abstract: The outmost layer of skin epidermis comprises of nanostructured corneocytes embedded in extracellular lipid matrix that endows the epidermis with permeative and protective properties. Inspired by such structure, here we produced multifunctional porous polymer films on hydrogels by a simple yet robust in situ interfacial precipitation polymerization of specific water-soluble monomers that become insoluble as they polymerize. This was applied on erse hydrogel substrates, yielding unusually durable interfaces which exhibited epidermis-like characteristics. For ex le, the polymer films possess a thickness of 20 to 330 µm and comprise of interconnected nanoparticles tightly bonded to hydrogel surfaces, which structurally resemble the layer of interlocked corneocytes in the epidermis. Due to these unique structural features, the film exhibits an excellent permeability towards small molecules in the first instance but can then be tailored towards effective protection from excess water loss and for enhanced electrical resistivity. These polymer films provide a platform for the development of engineered materials for erse applications.
Publisher: Wiley
Date: 11-02-2019
Abstract: The application of photochemistry to polymer and material science has led to the development of complex yet efficient systems for polymerization, polymer post-functionalization, and advanced materials production. Using light to activate chemical reaction pathways in these systems not only leads to exquisite control over reaction dynamics, but also allows complex synthetic protocols to be easily achieved. Compared to polymerization systems mediated by thermal, chemical, or electrochemical means, photoinduced polymerization systems can potentially offer more versatile methods for macromolecular synthesis. We highlight the utility of light as an energy source for mediating photopolymerization, and present some promising ex les of systems which are advancing materials production through their exploitation of photochemistry.
Publisher: Wiley
Date: 28-04-2016
Abstract: The polymerization of the photocleavable monomer, o-nitrobenzyl methacrylate (NBMA), is investigated using photoinduced electron/energy transfer reversible addition-fragmentation chain transfer polymerization. The polymerizations under visible red (λ max = 635 nm, 0.7 mW cm(-2) ) and yellow (λ max = 560 nm, 9.7 mW cm(-2) ) light are performed and demonstrate rational evidence of a controlled/living radical polymerization process. Well-defined poly(o-nitrobenzyl methacrylate) (PNBMA) homopolymers with good control over the molecular weight and polymer dispersity are successfully synthesized by varying the irradiation time and/or targeted degree of polymerization. Chain extension of a poly(oligo(ethylene glycol) methyl ether methacrylate) macro-chain transfer agent with NBMA is carried out to fabricate photocleavable hiphilic block copolymers (BCP). Finally, these self-assembled BCP rapidly dissemble under UV light suggesting the photoresponsive character of NBMA is not altered during the polymerization under yellow or red light. Such photoresponsive polymers can be potentially used for the remote-controlled delivery of therapeutic compounds.
Publisher: American Chemical Society (ACS)
Date: 23-12-2011
DOI: 10.1021/MA102386J
Publisher: Elsevier BV
Date: 12-2023
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1CC03927J
Abstract: Reversible addition/fragmentation chain transfer (RAFT) single unit monomer insertion of β-methylstyrene derivatives revealed significant degradation of products, which can be suppressed by selecting appropriate RAFT agents.
Publisher: American Chemical Society (ACS)
Date: 19-08-2009
DOI: 10.1021/MA901290A
Publisher: American Chemical Society (ACS)
Date: 27-08-2015
Publisher: Wiley
Date: 09-2016
Publisher: Wiley
Date: 17-03-2011
Abstract: A novel biodegradable thiazolidine-2-thione functional chain transfer agent was synthesized and employed as a reversible additional fragmentation chain transfer agent to prepare well-defined semitelechelic poly-N-(2-hydroxypropyl) methacrylamides (polyHPMAs) with predetermined molecular weights and narrow polydispersities. The protein reactive group, thiazolidine-2-thione, was located at the polymer chain ends fixed by biodegradable disulfide bonds. The functional polyHPMA chains were subsequently conjugated to protein (lysozyme) by exploiting reactions between the thiazolidine-2-thione functionality and amine residues on the protein surface to form covalent amide linkages. The in vitro bioactivities of the lysozyme-polyHPMA conjugates were assessed by using Micrococcus lysodeikticus cells as substrates. The lysozyme bioactivity was significantly reduced following the conjugation procedure. However, cleavage of the polymer chains from the bioconjugates (under reducing conditions) yielded free protein and a remarkable recovery of bioactivity. In vivo tests were performed by subcutaneous injection into mice and clearly demonstrated decreased proteolytic degradation for the protein-polymer conjugate when compared with native protein, indicating effective protein protection through a conjugation strategy. This bioreversible approach to conjugation allows for a balance to be made between protein protection and effective bioactivity maintenance.
Publisher: Wiley
Date: 10-12-2021
Abstract: Sequence plays a critical role in enabling unique properties and functions of natural biomolecules, which has promoted the rapid advancement of synthetic sequence‐defined polymers in recent decades. Particularly, investigation of short chain sequence‐defined oligomers (also called discrete oligomers) on their properties has become a hot topic. However, most studies have focused on discrete oligomers with conjugated structures. In contrast, unconjugated oligomers remain relatively underexplored. In this study, three pairs of discrete oligomers with the same composition but different sequence for each pair are employed for investigating their glass transition temperatures ( T g s). The resultant T g s of sequenced oligomers in each pair are found to be significantly different (up to 11.6 °C), attributable to variations in molecular packing as demonstrated by molecular dynamics and density function theory simulations. Intermolecular interaction is demonstrated to have less impact on T g s than intramolecular interaction. The mechanistic investigation into two model dimers suggests that monomer sequence caused the difference in intramolecular rotational flexibility of the sequenced oligomers. In addition, despite having different monomer sequence and T g s, the oligomers have very similar solubility parameters, which supports their potential use as effective oligomeric plasticizers to tune the T g s of bulk polymer materials.
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7PY00713B
Abstract: In this communication, we report a catalyst-free methodology for single unit monomer insertion (SUMI) into reversible addition–fragmentation chain transfer (RAFT) agents initiated by low intensity visible light.
Publisher: American Chemical Society (ACS)
Date: 25-02-2016
DOI: 10.1021/JACS.5B12408
Abstract: Here, we exploit the selectivity of photoactivation of thiocarbonylthio compounds to implement two distinct organic and polymer synthetic methodologies: (1) a single unit monomer insertion (SUMI) reaction and (2) selective, controlled radical polymerization via a visible-light-mediated photoinduced electron/energy transfer-reversible addition-fragmentation chain transfer (PET-RAFT) process. In the first method, precise single unit monomer insertion into a dithiobenzoate with a high reaction yield (>97%) is reported using an organic photoredox catalyst, pheophorbide a (PheoA), under red light irradiation (λmax = 635 nm, 0.4 mW/cm(2)). The exceptional selectivity of PheoA toward dithiobenzoate was utilized in combination with another catalyst, zinc tetraphenylporphine (ZnTPP), for the preparation of a complex macromolecular architecture. PheoA was first employed to selectively activate a dithiobenzoate, 4-cyanopentanoic acid dithiobenzoate, for the polymerization of a methacrylate backbone under red light irradiation. Subsequently, metalloporphyrin ZnTPP was utilized to selectively activate pendant trithiocarbonate moieties for the polymerization of acrylates under green light (λmax = 530 nm, 0.6 mW/cm(2)) to yield well-defined graft co-polymers.
Publisher: American Chemical Society (ACS)
Date: 10-11-2020
Publisher: American Chemical Society (ACS)
Date: 17-03-2021
Publisher: American Chemical Society (ACS)
Date: 23-03-2010
DOI: 10.1021/MA100142W
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7PY00442G
Abstract: The inhibitory effects of molecular oxygen in PET-RAFT polymerization can be overcome by the addition of singlet oxygen quenchers. This oxygen tolerant approach is compatible with a range of organic solvents and can be used to synthesize nanoparticles according to a PISA process.
Publisher: Springer Science and Business Media LLC
Date: 08-12-2022
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/C9TC04947A
Abstract: Flower-like Fe 3 O 4 @Au nanoparticles are constructed as bi-nano-bionic enzymes to catalyze the generation of hydroxyl radicals as an initiator for RAFT controlled polymerizations.
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9RE00014C
Abstract: A slug flow process has been utilised in conjunction with metal-free photopolymerisation to produce well-defined polymers with outstanding consistency.
Publisher: Wiley
Date: 05-07-2017
Publisher: American Chemical Society (ACS)
Date: 23-10-2017
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C4SC03342F
Abstract: We report an efficient photoinduced living radical polymerization process that involves the use of chlorophyll as the photoredox catalyst, which allows the preparation of well-defined polymers.
Publisher: American Chemical Society (ACS)
Date: 20-06-2014
DOI: 10.1021/MA500883Y
Publisher: Royal Society of Chemistry (RSC)
Date: 2009
DOI: 10.1039/B915512K
Abstract: Protein conjugation with biodegradable polyPEGMA and subsequent release is described.
Publisher: American Chemical Society (ACS)
Date: 13-07-2015
DOI: 10.1021/JACS.5B05274
Abstract: The use of metalloporphyrins has been gaining popularity particularly in the area of medicine concerning sensitizers for the treatment of cancer and dermatological diseases through photodynamic therapy (PDT), and advanced materials for engineering molecular antenna for harvesting solar energy. In line with the myriad functions of metalloporphyrins, we investigated their capability for photoinduced living polymerization under visible light irradiation over a broad range of wavelengths. We discovered that zinc porphyrins (i.e., zinc tetraphenylporphine (ZnTPP)) were able to selectively activate photoinduced electron transfer-reversible addition-fragmentation chain transfer (PET-RAFT) polymerization of trithiocarbonate compounds for the polymerization of styrene, (meth)acrylates and (meth)acrylamides under a broad range of wavelengths (from 435 to 655 nm). Interestingly, other thiocarbonylthio compounds (dithiobenzoate, dithiocarbamate and xanthate) were not effectively activated in the presence of ZnTPP. This selectivity was likely attributed to a specific interaction between ZnTPP and trithiocarbonates, suggesting novel recognition at the molecular level. This interaction between the photoredox catalyst and trithiocarbonate group confers specific properties to this polymerization, such as oxygen tolerance, enabling living radical polymerization in the presence of air and also ability to manipulate the polymerization rates (kp(app) from 1.2-2.6 × 10(-2) min(-1)) by varying the visible wavelengths.
Publisher: Wiley
Date: 11-09-2019
Publisher: American Chemical Society (ACS)
Date: 29-03-2023
DOI: 10.26434/CHEMRXIV-2023-LGJQ6
Abstract: In this communication, we disclose the use of a solid-phase methodology to synthesize iterative RAFT single unit mono-mer insertion (SUMI) adducts. This methodology features a reversible thiocarbonylthio protecting group and radical chain growth of vinyl monomers, with minimal purification required during the synthesis. To achieve this, a RAFT chain transfer agent was immobilized on a common peptide synthesis resin via the “R-group” in the first instance. Using an ox-ygen-tolerant PET-RAFT methodology, we then extended the iterative synthesis of sequence-defined indene-maleimide alternating co-oligomers to 18 units with minimal dispersity, completely unprecedented in SUMI chemistry. Furthermore, as we demonstrate, this solid-phase methodology can be generalized to other maleimide derivatives and other solid-phase resins.
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D0PY01413C
Abstract: The single unit monomer insertion technique provides a simple platform for the kinetic investigation of early stage of photo-RAFT process that comprises photo-activation of initial RAFT agents and addition of RAFT leaving radicals to the monomers.
Publisher: American Chemical Society (ACS)
Date: 04-2014
DOI: 10.1021/JA501745G
Abstract: Controlled/living radical polymerization techniques have transformed polymer chemistry in the last few decades, affording the production of polymers with precise control over both molecular weights and architectures. It is now possible to synthesize almost an infinite variety of macromolecules using nonspecialized equipment, finding applications in high-tech industry. However, they have several shortcomings. Until recently, living radical polymerizations could not be controlled by an external stimulus, such as visible light, pH, mechanical, chemical, etc. Moreover, they are usually sensitive to trace amounts of oxygen in the system. In this Article, we report a photoinduced living polymerization technique, which is able to polymerize a large range of monomers, including conjugated and unconjugated monomers, using ultralow concentrations of an iridium-based photoredox catalyst (typically 1 ppm to monomers) and a low energy visible LED as the light source (1-4.8 W, λ(max) = 435 nm). The synthesis of homopolymers with molecular weights ranging from 1000 to 2,000,000 g/mol was successfully achieved with narrow molecular weight distributions (M(w)/M(n) < 1.3). In addition, chain extensions of poly(methacrylate)s, poly(styrene), poly(N-vinyl pyrrolidinone), poly(vinyl ester)s, and poly(acrylate)s were performed to prepare diblock copolymers. The reusability of the catalyst was demonstrated by the synthesis of a decablock polymer by multiple chain extensions. Most importantly, this process was employed to prepare well-defined polymers and multiblock copolymers in the presence of air.
Publisher: American Chemical Society (ACS)
Date: 19-09-2018
DOI: 10.1021/JACS.8B08386
Abstract: Natural biopolymers, such as DNA and proteins, have uniform microstructures with defined molecular weight, precise monomer sequence, and stereoregularity along the polymer main chain that affords them unique biological functions. To reproduce such structurally perfect polymers and understand the mechanism of specific functions through chemical approaches, researchers have proposed using synthetic polymers as an alternative due to their broad chemical ersity and relatively simple manipulation. Herein, we report a new methodology to prepare sequence-controlled and stereospecific oligomers using alternating radical chain growth and sequential photoinduced RAFT single unit monomer insertion (photo-RAFT SUMI). Two families of cyclic monomers, the indenes and the N-substituted maleimides, can be alternatively inserted into RAFT agents, one unit at a time, allowing the monomer sequence to be controlled through sequential and alternating monomer addition. Importantly, the stereochemistry of cyclic monomer insertion into the RAFT agents is found to be trans-selective along the main chains due to steric hindrance from the repeating monomer units. All investigated cyclic monomers provide such trans-selectivity, but analogous acyclic monomers give a mixed cis- and trans-insertion.
Publisher: American Chemical Society (ACS)
Date: 07-06-2018
Publisher: American Chemical Society (ACS)
Date: 05-2006
DOI: 10.1021/MA060184N
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C4PY01123F
Abstract: Nontoxic and acid-degradable polymer vesicles were synthesized as drug carriers. In vitro dose–response cytotoxicity studies suggested that the drug-loaded polymer vesicles were more efficient in delivering cis-platin into cancer cells compared to the internalization of the free drug.
Publisher: Elsevier BV
Date: 08-2020
Publisher: American Chemical Society (ACS)
Date: 24-02-2017
Publisher: American Chemical Society (ACS)
Date: 14-06-2016
DOI: 10.1021/ACS.CHEMREV.6B00008
Abstract: Recent advances in controlled/living polymerization techniques and highly efficient coupling chemistries have enabled the facile synthesis of complex polymer architectures with controlled dimensions and functionality. As an ex le, star polymers consist of many linear polymers fused at a central point with a large number of chain end functionalities. Owing to this exclusive structure, star polymers exhibit some remarkable characteristics and properties unattainable by simple linear polymers. Hence, they constitute a unique class of technologically important nanomaterials that have been utilized or are currently under audition for many applications in life sciences and nanotechnologies. This article first provides a comprehensive summary of synthetic strategies towards star polymers, then reviews the latest developments in the synthesis and characterization methods of star macromolecules, and lastly outlines emerging applications and current commercial use of star-shaped polymers. The aim of this work is to promote star polymer research, generate new avenues of scientific investigation, and provide contemporary perspectives on chemical innovation that may expedite the commercialization of new star nanomaterials. We envision in the not-too-distant future star polymers will play an increasingly important role in materials science and nanotechnology in both academic and industrial settings.
Publisher: American Chemical Society (ACS)
Date: 19-09-2016
Publisher: American Chemical Society (ACS)
Date: 29-03-2023
DOI: 10.26434/CHEMRXIV-2023-60VB6
Abstract: Stereochemistry can significantly affect the chemical and physical properties of synthetic polymers. Compared to the structural precision of natural biomacromolecules (e.g. proteins and nucleic acids) that are chiral and enantiopure, fully controlling the stereochemistry of synthetic polymers is considerably more challenging. However, the development of next generation polymer materials will require increasing levels of microstructural control and an in-depth understanding of structure-property relationships. Herein, we assemble an unprecedented library of enantiopure oligomers, specifically indene-maleimide-indene trimers, with identical primary structure but different stereochemistry through a novel highly stereoselective radical addition process. Full characterization of these unique trimers reveals that the structural rigidity and molecular compactness are responsible for their unique physical properties, including crystallization, glass transition temperature and optical activity. This strategy provides an innovative means to build oligomeric blocks for synthetic polymers and tailor their physical properties.
Publisher: American Chemical Society (ACS)
Date: 16-06-2014
DOI: 10.1021/MZ500245K
Abstract: A novel and facile method, involving enzymatic monomer synthesis and a photocontrolled polymerization technique, has been successfully employed for the preparation of high-order multiblock copolymers. New acrylate monomers were synthesized via enzymatic transacylation between an activated monomer, i.e., 2,2,2-trifluoroethyl acrylate (TFEA), and various functional alcohols. These synthesized monomers were successfully polymerized without further purification via photoinduced electron transfer-reversible addition-fragmentation chain transfer (PET-RAFT) polymerization under low energy blue LED light (4.8 W) in the presence of an iridium-based photoredox catalyst (
Publisher: Royal Society of Chemistry (RSC)
Date: 2016
DOI: 10.1039/C6PY01361A
Abstract: The use of photocatalysts for visible light mediated reversible deactivation radical polymerization (RDRP) provides an efficient route for the synthesis of well-defined polymers with spatial, temporal and sequence control.
Publisher: Royal Society of Chemistry (RSC)
Date: 2016
DOI: 10.1039/C6CC03084J
Abstract: Visible light regulated ring opening polymerization in the presence of reversible merocyanine-based photoacid is reported in this article.
Publisher: Wiley
Date: 17-05-2016
Publisher: Wiley
Date: 08-12-2007
DOI: 10.1002/POLA.21798
Publisher: Wiley
Date: 27-10-2021
Publisher: Wiley
Date: 26-05-2017
Abstract: Recently, visible-light-regulated polymerization has been gaining popularity, as it opens a range of new opportunities for the synthesis of functional polymers and materials. Here, the most recent developments in this field are summarized, which is the use of photocatalysts and catalyst-free approaches to mediate polymerization upon photoexcitation. These catalysts can transfer an electron or energy to activate an initiator. The recent achievements in light-regulated atom-transfer radical polymerization, reversible addition-fragmentation chain-transfer polymerization, ring-opening metathesis polymerization, cobalt-mediated radical polymerization, iodine-mediated radical polymerization, and living cationic polymerization are reviewed. Recent development in these fields have solved important challenges in polymer chemistry, such as the development of oxygen-tolerant polymerization, polymerization mediated by near-infrared, metal-free polymerization, and spatial-, temporal-, and sequence-controlled polymerization. Some applications of these techniques will be discussed, such as adapting the current photocatalytic systems to synthesize heterogeneous photocatalysts that act as recyclable photocatalysts and novel light-mediated approaches for surface functionalization of hybrid materials and living cells. Finally, the existing challenges in polymer chemistry that could be overcome by further development of light-mediated polymerization techniques are highlighted along with the future directions of this field.
Publisher: Wiley
Date: 03-12-2016
Abstract: Photoregulated polymerizations are typically conducted using high-energy (UV and blue) light, which may lead to undesired side reactions. Furthermore, as the penetration of visible light is rather limited, the range of applications with such wavelengths is likewise limited. We herein report the first living radical polymerization that can be activated and deactivated by irradiation with near-infrared (NIR) and far-red light. Bacteriochlorophyll a (Bachl a) was employed as a photoredox catalyst for photoinduced electron transfer/reversible addition-fragmentation chain transfer (PET-RAFT) polymerization. Well-defined polymers were thus synthesized within a few hours under NIR (λ=850 nm) and far-red (λ=780 nm) irradiation with excellent control over the molecular weight (M(n)/M(w)<1.25). Taking advantage of the good penetration of NIR light, we showed that the polymerization also proceeded smoothly when a translucent barrier was placed between light source and reaction vessel.
Publisher: American Chemical Society (ACS)
Date: 17-07-2014
DOI: 10.1021/MA500842U
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7PY00007C
Abstract: A benchtop approach is developed for the synthesis of various polymeric architectures using an aqueous Reversible Addition–Fragmentation chain Transfer (RAFT) photopolymerization technique.
Publisher: MyJove Corporation
Date: 08-06-2016
DOI: 10.3791/54269
Publisher: Royal Society of Chemistry (RSC)
Date: 30-06-2014
DOI: 10.1039/C4SC01309C
Publisher: Elsevier BV
Date: 2007
Publisher: American Chemical Society (ACS)
Date: 05-05-2020
Publisher: American Chemical Society (ACS)
Date: 16-09-2019
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7CC07663K
Abstract: This work demonstrates use of spinach extracts for living radical polymerization bypassing catalyst synthesis urification, degassing and catalyst removal procedures.
Publisher: American Chemical Society (ACS)
Date: 27-01-2015
DOI: 10.1021/MA502460T
Publisher: American Chemical Society (ACS)
Date: 20-12-2018
Publisher: Wiley
Date: 11-09-2012
Abstract: The first ex le of core cross-linked star (CCS) polyrotaxane was prepared using the poly(ϵ-caprolactone) (PCL) CCS three-dimensional (3D) scaffold. The 3D CCS polymer was firstly prepared through the "arm-first" approach. Then, the "arms" of the resultant PCL CCS polymer were threaded with α-cyclodextrins (α-CDs). The threaded α-CDs were permanently locked by the "click" reaction of terminal alkyne functionalities of the star polymers with the azide-functionalized end caps to afford the CCS polyrotaxanes. All analytical results confirm the formation of the CCS polyrotaxanes and reveal their characteristics, including fluorescence under UV, a channel-type crystalline structure, a two-step thermal decomposition, and a unique core-shell structure in great contrast to the polymer precursors.
Publisher: Wiley
Date: 20-01-2022
Abstract: Advances in artificial/synthetic cells have drawn a new era of nanobiotechnology, which have shown broad prospects in biomedical applications. The rational nanoengineering of synthetic cells that can closely substitute the systematic biological functions of cells is a next grand challenge. Here, a genetically encoded synthetic beta cell, which can sense hyperglycemic conditions to initiate programmed biosynthesis and secretion of insulin is reported. By encapsulating different metal–organic framework‐based artificial organelles with distinctive bifunctionalities, the synthetic cell can undergo programmed, sequential subcellular events, including glucose sensing, initiation of insulin gene transcription and translation, and finally excretion of functional insulin, under hyperglycemic conditions. Glucose uptake assay suggests that the insulin produced by the synthetic cells can successfully promote glucose uptake into mammalian cells. The construction of a higher‐order cell cluster by ligand‐mediated super‐assembly of the synthetic cells is further demonstrated. Such a robust and smart synthetic system that closely mimics the cellular activities of beta cells in response to glucose levels is promising for improving clinical outcomes in diabetes treatment.
Publisher: American Chemical Society (ACS)
Date: 17-09-2018
Publisher: American Chemical Society (ACS)
Date: 30-01-2017
Publisher: American Chemical Society (ACS)
Date: 30-06-2022
DOI: 10.1021/ACSINFECDIS.2C00087
Abstract: The escalating issue of multidrug-resistant (MDR) bacteria indicates the urgent need for new and effective strategies to combat this global health challenge. Here, we describe a new combinatorial approach that can be put forward for experimental therapy application against MDR bacteria. Specifically, we have developed a tri-system that includes the coadministration of two different membrane-disrupting-type antimicrobial agents─a synthetic antimicrobial polymer
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/C9PY01419E
Abstract: For the first time, we report 3D printing of RAFT-based formulations to fabricate functional objects in a layer-by-layer fashion.
Publisher: Wiley
Date: 30-01-2019
DOI: 10.1002/POLA.29330
Publisher: Royal Society of Chemistry (RSC)
Date: 2014
DOI: 10.1039/C4PY00193A
Abstract: A facile method for post-functionalization of polymers with side olefin groups was developed by visible light-mediated atom transfer radical addition (ATRA) employing a photoredox catalyst, fac -Ir(ppy) 3 .
Publisher: Royal Society of Chemistry (RSC)
Date: 2016
DOI: 10.1039/C6CS00185H
Abstract: This review, with over 600 references, summarizes the recent applications of photoredox catalysis for organic transformation and polymer synthesis.
Publisher: American Chemical Society (ACS)
Date: 26-07-2022
Abstract: As emerging energy storage devices, aqueous zinc ion batteries (AZIBs) with outstanding advantages of high safety, high energy density, and environmental friendliness have attracted much research interest. Herein, the favorable thornlike MnO
Publisher: Springer Science and Business Media LLC
Date: 03-01-2014
Publisher: American Chemical Society (ACS)
Date: 22-03-2022
Publisher: American Chemical Society (ACS)
Date: 07-12-2010
DOI: 10.1021/MA902154H
Publisher: American Chemical Society (ACS)
Date: 21-10-2019
Publisher: Elsevier BV
Date: 09-2009
Publisher: American Chemical Society (ACS)
Date: 21-06-2007
DOI: 10.1021/MA070220Y
Publisher: American Chemical Society (ACS)
Date: 22-04-2019
DOI: 10.1021/JACS.9B01096
Abstract: In this work, we adopted a fully computer-guided strategy in discovering an efficient pH-switchable organic photocatalyst (OPC), unprecedentedly turning colorless at pH 5 and recovering strong visible-light absorption and photoactivity at pH 7. This is the first ex le of an OPC design fully guided by comprehensive density functional theory (DFT) studies covering electrostatic, electrochemical, and photophysical predictions. Characterization of the designed OPC after synthesis confirmed the computational predictions. We applied this OPC to mediate an aqueous photoinduced electron/energy transfer-reversible addition-fragmentation chain transfer (PET-RAFT) polymerization under green LED light (nominal emission wavelength: 530 nm, 5 mW/cm
Publisher: Wiley
Date: 15-02-2006
DOI: 10.1002/POLA.21335
Publisher: American Chemical Society (ACS)
Date: 11-2005
DOI: 10.1021/MA0513970
Publisher: Royal Society of Chemistry (RSC)
Date: 2023
DOI: 10.1039/D3PY00828B
Abstract: In this article, we disclose the use of a solid-phase methodology to synthesise iterative RAFT single unit monomer insertion (SUMI) adducts.
Publisher: Wiley
Date: 10-11-2020
Abstract: The photocatalyst Zn(II) meso-tetra(4-sulfonatophenyl)porphyrin (ZnTPPS) is found to substantially accelerate visible-light-initiated (red, yellow, green light) single unit monomer insertion (SUMI) of N,N-dimethylacrylamide into the reversible addition-fragmentation chain transfer (RAFT) agent, 4-((((2-carboxyethyl)thio)carbonothioyl)thio)-4-cyanopentanoic acid (RAFT
Publisher: CSIRO Publishing
Date: 2010
DOI: 10.1071/CH10168
Abstract: Poly(ethylene glycol) (PEG) hydrogels are water-swellable, non-toxic, non-immunogenic, and biocompatible. In this paper, we describe the generation of biodegradable PEG hydrogels by cross-linking biotinylated PEG oligomers containing intrinsic disulfide bonds via biotin-avidin interactions. The biotinylated PEG oligomers were synthesized by the condensation reaction between PEG and 3,3′-dithiodipropionic acid, followed by the reaction with biotin. This methodology obviates the need for potentially toxic chemical cross-linking agents that are usually used in the common preparation of hydrogels. Therefore it may be particularly useful in biomedical or pharmaceutical applications.
Publisher: Wiley
Date: 07-12-2016
Abstract: Uniform synthetic polymers with precisely defined molar mass and monomer sequence (primary structure) have many potential high-value applications. However, a robust and versatile synthetic strategy for these materials remains one of the great challenges in polymer synthesis. Herein we describe proof-of-principle experiments for a modular strategy to produce discrete oligomers by a visible-light-mediated radical chain process. We utilize the high selectivity provided by photo-induced electron/energy transfer (PET) activation to develop efficient single unit monomer insertion (SUMI) into reversible addition-fragmentation chain-transfer (RAFT) agents. A variety of discrete oligomers (single unit species, dimers, and, for the first time, trimers) have been synthesized by sequential SUMI in very high yield under mild reaction conditions. The trimers were used as building blocks for the construction of uniform hexamers and graft copolymers with precisely defined branches.
Publisher: American Chemical Society (ACS)
Date: 29-04-2016
Publisher: American Chemical Society (ACS)
Date: 16-01-2020
Publisher: Royal Society of Chemistry (RSC)
Date: 2009
DOI: 10.1039/B907061C
Abstract: A novel thiazolidine-2-thione functionalized chain transfer agent (CTA) was synthesized and used as a reversible addition-fragmentation chain transfer (RAFT) polymerization agent to prepare well-defined poly-N-(2-hydroxypropyl) methacrylamide (PHPMA). The polymer chains had pre-designed molecular weights, narrow polydispersities and were chain-end functionalized. On incubation with protein (lysozyme) under different pH conditions, PHPMA was conjugated to the protein surface via covalent amide bonding. The bioactivity of the lysozyme-PHPMA conjugates was assessed using Micrococcus lysodeikticus (Ml) cells as substrates. The number of polymer chains attached to the protein could be controlled by both the pH of the conjugation reaction and the molecular weights of the polymers, thereby influencing significantly the bioactivity of the protein-polymer conjugates.
Publisher: American Chemical Society (ACS)
Date: 17-03-2016
DOI: 10.1021/ACSMACROLETT.6B00121
Abstract: Well-defined poly(ε-caprolactone)-
Publisher: Wiley
Date: 07-07-2020
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8PY00366A
Abstract: A library of N -acryloylamino acid polymers with controlled molecular weights and narrow molecular weight distributions ( M w / M n 1.20) was created by a universal and versatile photoinduced living radical polymerization technique.
Publisher: American Chemical Society (ACS)
Date: 24-01-2020
Publisher: American Chemical Society (ACS)
Date: 23-09-2015
Publisher: Wiley
Date: 21-07-2009
DOI: 10.1002/POLA.23482
Publisher: American Chemical Society (ACS)
Date: 09-02-2018
Publisher: Wiley
Date: 08-11-2022
Abstract: Solar steam generator (SSG) systems have attracted increasing attention, owing to its simple manufacturing, material abundance, cost‐effectiveness, and environmentally friendly freshwater production. This system relies on photothermic materials and water absorbing substrates for a clean continuous distillation process. To optimize this process, there are factors that are needed to be considered such as selection of solar absorber and water absorbent materials, followed by micro/macro‐structural system design for efficient water evaporation, floating, and filtration capability. In this contribution, we highlight the general interfacial SSG concept, review and compare recent progresses of different SSG systems, as well as discuss important factors on performance optimization. Furthermore, unaddressed challenges such as SSG's cost to performance ratio, filtration of untreatable micropollutants/microorganisms, and the need of standardization testing will be discussed to further advance future SSG studies.
Publisher: Wiley
Date: 19-01-2020
Abstract: Metal‐organic frameworks (MOFs) have recently emerged as excellent hosting matrices for enzyme immobilization, offering superior physical and chemical protection for biocatalytic reactions. However, for multienzyme and cofactor‐dependent biocatalysis, the subtle orchestration of enzymes and cofactors is largely disrupted upon immobilizing in the rigid crystalline MOF network, which leads to a much reduced biocatalytic efficiency. Herein, we constructed hierarchically porous MOFs by controlled structural etching to enhance multienzyme and cofactor‐dependent enzyme biocatalysis. The expanded size of the pores can provide sufficient space for accommodated enzymes to reorientate and spread within MOFs in their lower surface energy state as well as to decrease the inherent barriers to accelerate the diffusion rate of reactants and intermediates. Moreover, the developed hierarchically porous MOFs demonstrated outstanding tolerance to inhospitable surroundings and recyclability.
Publisher: Elsevier BV
Date: 03-2018
Publisher: American Chemical Society (ACS)
Date: 02-09-2016
Publisher: American Chemical Society (ACS)
Date: 03-10-2023
Publisher: Wiley
Date: 05-07-2217
Publisher: American Chemical Society (ACS)
Date: 10-11-2006
DOI: 10.1021/MA061961M
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C7PY01690E
Abstract: Fibrous and porous monolithic cellulose was employed to immobilize a photocatalyst for heterogeneously catalysing controlled radical polymerization, which provides superior catalyst recyclability.
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C4PY01317D
Abstract: In this work, we demonstrate the use of organophotoredox catalysts under visible light to perform photoinduced electron transfer-reversible addition fragmentation chain transfer (PET-RAFT) for the polymerization of methacrylate monomers.
Publisher: American Chemical Society (ACS)
Date: 24-10-2017
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8CC02783H
Abstract: Photoinduced electron/energy transfer-reversible addition–fragmentation chain transfer (PET-RAFT) process has opened up a new way of precision polymer manufacturing to satisfy the concept of green chemistry.
Publisher: American Chemical Society (ACS)
Date: 17-08-2015
Publisher: Springer Science and Business Media LLC
Date: 26-08-2019
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D1PY01581H
Abstract: In this Perspective, we outline advances and challenges in controlling the structure of polymers at various size regimes in the context of structural features such as molecular weight distribution, end groups, architecture, composition and sequence.
Publisher: Wiley
Date: 19-01-2021
Abstract: Metal‐organic frameworks (MOFs) have recently emerged as excellent hosting matrices for enzyme immobilization, offering superior physical and chemical protection for biocatalytic reactions. However, for multienzyme and cofactor‐dependent biocatalysis, the subtle orchestration of enzymes and cofactors is largely disrupted upon immobilizing in the rigid crystalline MOF network, which leads to a much reduced biocatalytic efficiency. Herein, we constructed hierarchically porous MOFs by controlled structural etching to enhance multienzyme and cofactor‐dependent enzyme biocatalysis. The expanded size of the pores can provide sufficient space for accommodated enzymes to reorientate and spread within MOFs in their lower surface energy state as well as to decrease the inherent barriers to accelerate the diffusion rate of reactants and intermediates. Moreover, the developed hierarchically porous MOFs demonstrated outstanding tolerance to inhospitable surroundings and recyclability.
Publisher: Wiley
Date: 26-09-2020
DOI: 10.1002/POL.20200567
Publisher: Wiley
Date: 13-06-2021
Abstract: A series of poly( N ‐isopropylacrylamide) (PNIPAm) homopolymers with narrow molecular weight distributions (MWDs) is prepared via photoinduced electron/energy transfer–reversible addition‐fragmentation chain transfer (PET–RAFT) polymerization. The thermal transition temperature of these polymer s les is analyzed via turbidity measurements in water/ N , N' ‐dimethylformamide mixtures, which show that the cloud point temperatures are inversely proportional to the weight average molecular weight ( M w ). Binary mixtures of the narrowly distributed PNIPAm s les are also prepared and the statistical parameters for the MWDs of these blends are determined. Very interestingly, for binary blends of the PNIPAm s les, the thermoresponsive transition is not only dependent on the M w , which has been shown previously, but also on higher order statistical parameters of the MWDs. Specifically, at very high values of skewness and kurtosis, the polymer blends deviate from a single sharp thermoresponsive transition toward a broader thermal response, and eventually to a regime of two more distinct transitions. This work highlights the importance of in‐depth characterization of polymer MWDs for thermoresponsive polymers.
Publisher: Wiley
Date: 13-10-2020
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0PY00390E
Abstract: A complete set of model trimers and their synthetic kinetics are established to guide the synthesis of erse sequence-defined polymers.
Publisher: Wiley
Date: 07-12-2016
Publisher: American Chemical Society (ACS)
Date: 12-10-2021
Publisher: American Chemical Society (ACS)
Date: 14-12-2016
Publisher: American Chemical Society
Date: 2018
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/C9EE03408K
Abstract: This review proposes the concept of covalent fixing as a new research strategy for sulfur electrochemistry in advanced metal–sulfur batteries.
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1QM00329A
Abstract: This work presents the design, synthesis, crystal growth, and property characterization of a fluorinated Ruddlesden–Popper perovskite (3-FPEA) 2 PbI 4 .
Publisher: Royal Society of Chemistry (RSC)
Date: 2013
DOI: 10.1039/C2CC37319J
Abstract: A simple and straightforward method of self-assembling grafted copolymers was developed to fabricate cross-linked polymer vesicles, which could conjugate anticancer drug cis-platinum and possess the capability of a high drug loading content, and a steady release rate.
Start Date: 2017
End Date: 2020
Funder: Australian Research Council
View Funded ActivityStart Date: 2017
End Date: 06-2021
Amount: $652,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 07-2021
End Date: 12-2024
Amount: $380,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2019
End Date: 05-2022
Amount: $360,000.00
Funder: Australian Research Council
View Funded Activity