ORCID Profile
0000-0002-6475-0797
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Publisher: American Thoracic Society
Date: 11-1997
DOI: 10.1164/AJRCCM.156.5.97-03007
Abstract: The objectives of this study were to measure the population prevalence of symptoms of chronic obstructive lung disease and mild airway obstruction and to compare these between occupational groups. There were 1,609 subjects (63.9% response rate) who completed a respiratory questionnaire. Of these, 1,132 (70.4%) underwent pulmonary function testing (FEV1 and FVC). Twenty-one categories of current occupation were used for analysis. Four definitions of chronic obstructive pulmonary disease (COPD) were used: (1) chronic bronchitis, (2) chronic bronchitis with airway obstruction, (3) shortness of breath, and (4) shortness of breath with airway obstruction. For chronic bronchitis, adjusted prevalence odds ratios were significantly elevated for food processors other than bakers (OR = 2.83 95% CI, 1.27 to 6.29) and chemical processors (OR = 18.84 3.71 to 95.64). The combination of chronic bronchitis and mild airway obstruction (FEV1/FVC < 0.75) was associated with bakers (OR = 25.5 3.86 to 168.53) and spray painters (OR = 14.40 2.85-72.69). Shortness of breath was associated with hairdressers (OR = 2.75 0.80 to 9.42) and bakers (OR = 6.72 0.57 to 79.66), and nursing was associated with lower levels of shortness of breath (OR = 0.42 0.16 to 1.15). Working ever with vapors, gases, dust, or fumes was significantly associated with chronic bronchitis and airway obstruction (OR = 3.13 1.07 to 9.12). This population-based study has identified certain occupations with increased prevalence of chronic bronchitis and COPD.
Publisher: Cambridge University Press (CUP)
Date: 2013
DOI: 10.1017/PASA.2013.22
Abstract: We present the first results from a new carbon monoxide (CO) survey of the southern Galactic plane being conducted with the Mopra radio telescope in Australia. The 12 CO, 13 CO, and C 18 O J = 1–0 lines are being mapped over the $l = 305^{\\circ }\\text{--} 345^{\\circ }, b = \\pm 0.5^{\\circ }$ portion of the fourth quadrant of the Galaxy, at 35 arcsec spatial and 0.1 km s −1 spectral resolution. The survey is being undertaken with two principal science objectives: (i) to determine where and how molecular clouds are forming in the Galaxy and (ii) to probe the connection between molecular clouds and the ‘missing’ gas inferred from gamma-ray observations. We describe the motivation for the survey, the instrumentation and observing techniques being applied, and the data reduction and analysis methodology. In this paper, we present the data from the first degree surveyed, $l = 323^{\\circ } \\text{--} 324^{\\circ }, b = \\pm 0.5^{\\circ }$ . We compare the data to the previous CO survey of this region and present metrics quantifying the performance being achieved the rms sensitivity per 0.1 km s −1 velocity channel is ~1.5 K for ${\\rm ^{12}CO}$ and ~0.7 K for the other lines. We also present some results from the region surveyed, including line fluxes, column densities, molecular masses, ${\\rm ^{12}CO/^{13}CO}$ line ratios, and ${\\rm ^{12}CO}$ optical depths. We also examine how these quantities vary as a function of distance from the Sun when averaged over the 1 square degree survey area. Approximately 2 × 10 6 M ⊙ of molecular gas is found along the G323 sightline, with an average H 2 number density of $n_{\\text{H}_2} \\sim 1$ cm −3 within the Solar circle. The CO data cubes will be made publicly available as they are published.
Publisher: Cambridge University Press (CUP)
Date: 2018
DOI: 10.1017/PASA.2018.18
Abstract: We present observations of 50 deg 2 of the Mopra carbon monoxide (CO) survey of the Southern Galactic Plane, covering Galactic longitudes l = 300–350° and latitudes | b | ⩽ 0.5°. These data have been taken at 0.6 arcmin spatial resolution and 0.1 km s −1 spectral resolution, providing an unprecedented view of the molecular clouds and gas of the Southern Galactic Plane in the 109–115 GHz J = 1–0 transitions of 12 CO, 13 CO, C 18 O, and C 17 O. We present a series of velocity-integrated maps, spectra, and position-velocity plots that illustrate Galactic arm structures and trace masses on the order of ~10 6 M ⊙ deg −2 , and include a preliminary catalogue of C 18 O clumps located between l = 330–340°. Together with the information about the noise statistics of the survey, these data can be retrieved from the Mopra CO website and the PASA data store.
Publisher: Oxford University Press (OUP)
Date: 21-12-2012
Publisher: Elsevier BV
Date: 02-1991
DOI: 10.1016/0005-2760(91)90277-O
Abstract: Human patients with familial hypercholesterolemia (FH) and Watanabe heritable hyperlipidemic rabbits (WHHL), while lacking normal receptors recognizing low-density lipoproteins (LDL), are said to have normal clearance of chylomicrons. In the present study, emulsions with a similar lipid composition to chylomicrons were injected intravenously in homozygous WHHL rabbits and normal control rabbits fed diet with low or high cholesterol. Radioactive labels tracing emulsion triolein and cholesteryl oleate were both removed rapidly from the bloodstream, with the removal rate of triolein always faster than that of cholesteryl oleate. This pattern was similar to the clearance of normal chylomicrons in rabbits or rats, and was consistent with the formation of remnant lipoproteins after hydrolysis of emulsion triolein by lipoprotein lipase, followed by hepatic uptake of the remnants. The removal of cholesteryl oleate was significantly slower in WHHL rabbits than in normal controls, suggesting that the absence of LDL receptor function led to impaired remnant clearance. Measured in post-heparin plasma, the activity of lipoprotein lipase was decreased in WHHL rabbits, but this was not associated with clear evidence of defective lipolysis of emulsion triolein. Apolipoprotein E did not appear to be deficient in WHHL rabbits. Plasma devoid of lipoproteins less than 1.006 g/ml from WHHL and normal control rabbits transferred similar amounts of apolipoprotein E to chylomicron-like emulsions after incubation. Impaired clearance of chylomicron remnants possibly contributes to the hypertriglyceridemia of WHHL rabbits and to accelerated atherogenesis when the function of LDL receptors is defective.
Publisher: Elsevier BV
Date: 02-1998
Publisher: Author(s)
Date: 2017
DOI: 10.1063/1.4968938
Publisher: American Astronomical Society
Date: 29-01-2014
Publisher: Cambridge University Press (CUP)
Date: 2019
DOI: 10.1017/PASA.2019.7
Abstract: We investigate the interstellar medium towards seven TeV gamma-ray sources thought to be pulsar wind nebulae using Mopra molecular line observations at 7 mm [CS(1–0), SiO(1–0, v = 0)], Nanten CO(1–0) data and the Southern Galactic Plane Survey/GASS H i survey. We have discovered several dense molecular clouds co-located to these TeV gamma-ray sources, which allows us to search for cosmic rays coming from progenitor SNRs or, potentially, from pulsar wind nebulae. We notably found SiO(1–0, v = 0) emission towards HESS J1809–193, highlighting possible interaction between the adjacent supernova remnant SNR G011.0–0.0 and the molecular cloud at d ∼ 3.7 kpc. Using morphological features, and comparative studies of our column densities with those obtained from X-ray measurements, we claim a distance d ∼ 8.6 − 9.7kpc for SNR G292.2–00.5, d ∼ 3.5 − 5.6 kpc for PSR J1418–6058 and d ∼ 1.5 kpc for the new SNR candidate found towards HESS J1303–631. From our mass and density estimates of selected molecular clouds, we discuss signatures of hadronic/leptonic components from pulsar wind nebulae and their progenitor SNRs. Interestingly, the molecular gas, which overlaps HESS J1026–582 at d ∼ 5 kpc, may support a hadronic origin. We find however that this scenario requires an undetected cosmic-ray accelerator to be located at d 10 pc from the molecular cloud. For HESS J1809–193, the cosmic rays which have escaped SNR G011.0–0.0 could contribute to the TeV gamma-ray emission. Finally, from the hypothesis that at most 20% the pulsar spin down power could be converted into CRs, we find that among the studied pulsar wind nebulae, only those from PSR J1809–1917 could potentially contribute to the TeV emission.
Publisher: Oxford University Press (OUP)
Date: 06-09-2017
Publisher: Cambridge University Press (CUP)
Date: 2015
DOI: 10.1017/PASA.2015.20
Abstract: We present observations of the first 10° of longitude in the Mopra CO survey of the southern Galactic plane, covering Galactic longitude l = 320–330° and latitude b = ±0.5°, and l = 327–330°, b = +0.5–1.0°. These data have been taken at 35-arcsec spatial resolution and 0.1 km s −1 spectral resolution, providing an unprecedented view of the molecular clouds and gas of the southern Galactic plane in the 109–115 GHz J = 1–0 transitions of 12 CO, 13 CO, C 18 O, and C 17 O. Together with information about the noise statistics from the Mopra telescope, these data can be retrieved from the Mopra CO website and the CSIRO-ATNF data archive.
Publisher: Springer Science and Business Media LLC
Date: 15-01-2020
DOI: 10.1186/S40798-019-0232-X
Abstract: Performance analysis in rugby union has become an integral part of the coaching process. Although performance analysis research in rugby and data collection has progressed, the utility of the insights is not well understood. The primary objective of this review is to consider the current state of performance analysis research in professional rugby union and consider the utility of common methods of analysing performance and the applicability of these methods within professional coaching practice. SPORTDiscus electronic database was searched for relevant articles published between 1 January 1997 and 7 March 2019. Professional, male 15-a-side rugby union studies that included relevant data on tactical and performance evaluation, and statistical compilation of time-motion analysis were included. Studies were categorised based on the main focus and each study was reviewed by assessing a number of factors such as context, opposition analysis, competition and s le size. Forty-one studies met the inclusion criteria. The majority of these studies measured performance through the collection and analysis of performance indicators. The majority did not provide context relating to multiple confounding factors such as field location, match location and opposition information. Twenty-nine performance indicators differentiated between successful match outcomes however, only eight were commonly shared across some studies. Five studies considered rugby union as a dynamical system however, these studies were limited in analysing lower or national-level competitions. The review highlighted the issues associated with assessing isolated measures of performance, lacking contextual information such as the opposition, match location, period within match and field location. A small number of studies have assessed rugby union performance through a dynamical systems lens, identifying successful characteristics in collective behaviour patterns in attacking phases. Performance analysis in international rugby union can be advanced by adopting these approaches in addition to methods currently adopted in other team sports.
Publisher: Elsevier BV
Date: 08-2000
Publisher: Oxford University Press (OUP)
Date: 10-04-2014
DOI: 10.1093/JXB/ERU133
Abstract: Polyamines regulate a variety of cation and K(+) channels, but their potential effects on cation-transporting ATPases are underexplored. In this work, noninvasive microelectrode ion flux estimation and conventional microelectrode techniques were applied to study the effects of polyamines on Ca(2+) and H(+) transport and membrane potential in pea roots. Externally applied spermine or putrescine (1mM) equally activated eosin yellow (EY)-sensitive Ca(2+) pumping across the root epidermis and caused net H(+) influx or efflux. Proton influx induced by spermine was suppressed by EY, supporting the mechanism in which Ca(2+) pump imports 2 H(+) per each exported Ca(2+). Suppression of the Ca(2+) pump by EY diminished putrescine-induced net H(+) efflux instead of increasing it. Thus, activities of Ca(2+) and H(+) pumps were coupled, likely due to the H(+)-pump inhibition by intracellular Ca(2+). Additionally, spermine but not putrescine caused a direct inhibition of H(+) pumping in isolated plasma membrane vesicles. Spermine, spermidine, and putrescine (1mM) induced membrane depolarization by 70, 50, and 35 mV, respectively. Spermine-induced depolarization was abolished by cation transport blocker Gd(3+), was insensitive to anion channels' blocker niflumate, and was dependent on external Ca(2+). Further analysis showed that uptake of polyamines but not polyamine-induced cationic (K(+)+Ca(2+)+H(+)) fluxes were a main cause of membrane depolarization. Polyamine increase is a common component of plant stress responses. Activation of Ca(2+) efflux by polyamines and contrasting effects of polyamines on net H(+) fluxes and membrane potential can contribute to Ca(2+) signalling and modulate a variety of transport processes across the plasma membrane under stress.
Publisher: American Diabetes Association
Date: 02-02-2009
DOI: 10.2337/DB08-1595
Abstract: The purpose of this study was to examine the effects of weight loss on sympathetic nervous system responsiveness to glucose ingestion in obese subjects with metabolic syndrome, in whom such responses are reportedly blunted. Thirty four subjects, 19 insulin resistant and 15 insulin sensitive and aged 55 ± 1 years (mean ± SE) with BMI 31.6 ± 0.6 kg/m2, who fulfilled the Adult Treatment Panel III criteria for metabolic syndrome participated. Simultaneous measurements of whole-body norepinephrine spillover rate, calf blood flow, and intra-arterial blood pressure were made at times 0, 30, 60, 90, and 120 min postglucose (75 g). The experiment was repeated after a 3-month hypocaloric diet with or without an exercise program. Body weight decreased by 8.1 ± 0.9 and 8.4 ± 1.1 kg and resting norepinephrine spillover by 94 ± 31 and 166 ± 58 ng/min (all P ≤ 0.01) in insulin-resistant and insulin-sensitive subjects, respectively. Weight loss was accompanied by a marked increase in sympathetic responsiveness after glucose but only in insulin-resistant subjects. In this subgroup, comparative increases in norepinephrine spillover rates at baseline and after weight loss averaged −3 ± 25 versus 73 ± 24 ng/min at 30 min (P = 0.039), 36 ± 21 versus 115 ± 28 ng/min at 60 min (P = 0.045), 9 ± 21 versus 179 ± 50 ng/min at 90 min (P & 0.001), and 40 ± 48 versus 106 ± 39 ng/min at 120 min (P = 0.24). Weight loss reverses blunted sympathetic responsiveness to glucose ingestion in insulin-resistant subjects with metabolic syndrome, which is relevant to postprandial energy utilization and body weight homeostasis.
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 23-10-2007
Publisher: American Astronomical Society
Date: 22-01-2015
Publisher: Oxford University Press (OUP)
Date: 07-12-2018
Publisher: Cambridge University Press (CUP)
Date: 08-2015
DOI: 10.1017/S1743921316007717
Abstract: We present spectral data cubes of the [CI] 809 GHz, 12 CO 115 GHz, 13 CO 110 GHz and HI 1.4 GHz line emission from a ~1° region along the l = 328° (G328) sightline in the Galactic Plane. The [CI] data comes from the High Elevation Antarctic Terahertz telescope at Ridge A on the summit of the Antarctic plateau, where the extremely low levels of precipitable water vapour open atmospheric windows for THz observations. The CO data comes from the Southern Galactic Plane Survey being conducted with the Mopra telescope. Emission arises principally from gas in three spiral arm crossings along the sight line. The distribution of the emission in the CO and [CI] lines is found to be similar, with the [CI] slightly more extended, and both are enveloped in extensive HI. Spectral line ratios are similar across the entire extent of the Galaxy. However, towards the edges of the molecular clouds the [CI]/ 13 CO and 12 CO/ 13 CO line ratios rise by ~ 50%, and the [CI]/H i ratio falls by ~ 10%. We attribute this to sightlines passing predominantly through the surfaces of photodissociation regions (PDRs), where the carbon is found mainly as C or C + rather than CO, while the gas is mostly molecular. This is the signature of dark molecular gas.
Publisher: American Astronomical Society
Date: 23-06-2015
Publisher: American Astronomical Society
Date: 09-05-2017
Publisher: Oxford University Press (OUP)
Date: 11-2017
Publisher: Cambridge University Press (CUP)
Date: 2017
DOI: 10.1017/PASA.2017.59
Abstract: HESS J1614–518 and HESS J1616–508 are two tera-electron volt γ-ray sources that are not firmly associated with any known counterparts at other wavelengths. We investigate the distribution of interstellar medium towards the tera-electron volt γ-ray sources using results from a 7-mm-wavelength Mopra study, the Mopra Southern Galactic Plane CO Survey, the Millimetre Astronomer’s Legacy Team-45 GHz survey and [C i ] data from the HEAT telescope. Data in the CO(1–0) transition lines reveal diffuse gas overlapping the two tera-electron volt sources at several velocities along the line of sight, while observations in the CS(1–0) transition line reveal several interesting dense gas features. To account for the diffuse atomic gas, archival H i data was taken from the Southern Galactic Plane Survey. The observations reveal gas components with masses ~10 3 to 10 5 M ⊙ and with densities ~10 2 to 10 3 cm −3 overlapping the two tera-electron volt sources. Several origin scenarios potentially associated with the tera-electron volt γ-ray sources are discussed in light of the distribution of the local interstellar medium. We find no strong convincing evidence linking any counterpart with HESS J1614–518 or HESS J1616–508.
Publisher: Oxford University Press (OUP)
Date: 14-03-2012
Publisher: Springer Science and Business Media LLC
Date: 04-12-2017
DOI: 10.1007/S00431-017-3049-Y
Abstract: Blood pressure (BP) is variable in children and this could affect BP assessment, but the magnitude of within-visit BP variability (BPV) over consecutive measurements has never been investigated. This study aimed to determine the direction and magnitude of, and factors affecting, within-visit BPV in children and adolescents. BP was recorded among 3047 children (aged 12 years [95%CI 12, 13], males 52%) from the 2011-2013 Australian Health Survey. BPV was defined as the absolute difference (∆SBP BP is highly variable in children and adolescents, with the magnitude of variability being associated with both age and BP level. SBP increases on repeat measurement in a substantial proportion of the population. The optimal protocol of BP assessment to address this increased BPV needs to be determined. What is Known: • Diagnosis of elevated blood pressure (BP) is based on strict probabilistic criteria, the difference between the 90th (pre-hypertension) and 95th (hypertension) percentiles only being 3-4 mmHg. • BP variability could affect BP classification among children and adolescents. What is New: • The magnitude of BP change among children and adolescents is highly affected by BP level and age. • BP does not always drop on consecutive measurements, and evidence-based BP assessment protocols should be established to avoid misdiagnosis of hypertension.
Publisher: Wiley
Date: 18-08-2020
DOI: 10.1111/TPJ.14935
Publisher: SAGE Publications
Date: 04-2003
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 14-12-2004
DOI: 10.1161/01.CIR.0000149748.79945.52
Abstract: Background— Impaired endothelium-dependent NO-mediated vasodilation is a key feature of essential hypertension and may precede the increase in blood pressure. We investigated whether transport of the NO precursor l -arginine is related to decreased endothelial function. Methods and Results— Radiotracer kinetics ([ 3 H] l -arginine) were used to measure forearm and peripheral blood mononuclear cell arginine uptake in hypertensive subjects (n=12) and in 2 groups of healthy volunteers with (n=15) and without (n=15) a family history of hypertension. In conjunction, forearm blood flow responses to acetylcholine and sodium nitroprusside were measured before and after a supplemental intra-arterial infusion of l -arginine. In vivo and in vitro measures of l -arginine transport were substantially reduced in the essential hypertension and positive family history groups compared with the negative family history group however, no difference was detected in peripheral blood mononuclear cell mRNA or protein expression levels for the cationic amino acid transporter CAT-1. Plasma concentrations of l -arginine and N G , N G′ -dimethylarginine (ADMA) did not differ between groups. l -Arginine supplementation improved the response to acetylcholine only in subjects with essential hypertension and positive family history. Conclusions— Similar to their hypertensive counterparts, normotensive in iduals at high risk for the development of hypertension are characterized by impaired l -arginine transport, which may represent the link between a defective l -arginine/NO pathway and the onset of essential hypertension. The observed transport defect is not due to apparent alterations in CAT-1 expression or elevated endogenous ADMA.
Publisher: Oxford University Press (OUP)
Date: 14-08-2017
Publisher: Hindawi Limited
Date: 2014
DOI: 10.1155/2014/919054
Abstract: With many developed countries experiencing the aging of the population, older people play a large role in contributing to environmental problems but also to environmental solutions. The purpose of this research is to understand the awareness and behavior of current older people living in retirement villages towards sustainability development. To achieve this, a sustainability literacy survey was conducted with 65 older residents of a private retirement village located 10 Km outside the Brisbane, Australia’s central business district (CBD). Most of residents recognized the importance of environment protection and would like to lead a more environmentally friendly lifestyle. In addition, the majority were willing to pay higher prices for a living environment with sustainable features. The importance of positive social communications was emphasized with most residents having established good relationships with others in the village. The findings provide an important insight into consumer perspectives regarding the sustainable features that should and can be incorporated into the village planning and development.
Publisher: Wiley
Date: 05-08-2014
DOI: 10.1002/RCM.6982
Abstract: In recent years, research and applications of the N2O site-specific nitrogen isotope composition have advanced, reflecting awareness of the contribution of N2O to the anthropogenic greenhouse effect, and leading to significant progress in instrument development. Further dissemination of N2O isotopomer analysis, however, is h ered by a lack of internationally agreed gaseous N2O reference materials and an uncertain compatibility of different laboratories and analytical techniques. In a first comparison approach, eleven laboratories were each provided with N2O at tropospheric mole fractions (target gas T) and two reference gases (REF1 and REF2). The laboratories analysed all gases, applying their specific analytical routines. Compatibility of laboratories was assessed based on N2O isotopocule data for T, REF1 and REF2. Results for T were then standardised using REF1 and REF2 to evaluate the potential of N2O reference materials for improving compatibility between laboratories. Compatibility between laboratories depended on the analytical technique: isotope ratio mass spectrometry (IRMS) results showed better compatibility for δ(15)N values, while the performance of laser spectroscopy was superior with respect to N2O site preference. This comparison, however, is restricted by the small number of participating laboratories applying laser spectroscopy. Offset and two-point calibration correction of the N2O isotopomer data significantly improved the consistency of position-dependent nitrogen isotope data while the effect on δ(15)N values was only minor. The study reveals that for future research on N2O isotopocules, standardisation against N2O reference material is essential to improve interlaboratory compatibility. For atmospheric monitoring activities, we suggest N2O in whole air as a unifying scale anchor.
Publisher: American Astronomical Society
Date: 07-11-2019
Publisher: Elsevier BV
Date: 02-1991
DOI: 10.1016/0167-4889(91)90192-Z
Abstract: The role of the transferrin homologue, melanotransferrin (p97), in iron metabolism has been studied using the human melanoma cell line, SK-MEL-28, which expresses this antigen in high concentrations. The release of iron and transferrin were studied after prelabelling cells with human transferrin doubly labelled with iron-59 and iodine-125. Approx. 45% of internalised iron was in ferritin with little redistribution during reincubation. Iron release was linear with time, while transferrin release was biphasic, suggesting that iron was leaving the cell independently of transferrin. Unlabelled diferric transferrin increased transferrin release, implying a degree of coupling between cell surface binding, internalisation and release of transferrin. Increasing the preincubation time increased the amount of transferrin which remained internalised within the cell. A membrane-bound, iron-binding component with properties consistent with melanotransferrin was observed. Desferrioxamine or pyridoxal isonicotinoyl hydrazone could not remove iron from this compartment, suggesting a high affinity for iron. The number of membrane iron-binding molecules per cell was estimated to be 387,000 +/- 7000 . The non-transferrin-bound membrane Fe did not decrease during reincubation periods up to 5 h, suggesting that the cell was not utilising it. Hence, melanotransferrin may not have a role in internalising iron in melanoma cells.
Publisher: Oxford University Press (OUP)
Date: 31-12-2015
Publisher: Elsevier BV
Date: 04-2003
DOI: 10.1016/S0378-5173(03)00087-5
Abstract: The concept of controlled drug delivery has been traditionally used to obtain specific release rates or spatial targeting of active ingredients. The phenomenon of bioadhesion, introduced by Park and Robinson [Park, K., Robinson, J.R., 1984. Bioadhesive polymers as platforms for oral controlled drug delivery: method to study bioadhesion. Int. J. Pharm. 198, 107-127], has been studied extensively in the last decade and applied to improve the performance of these drug delivery systems. Recent advances in polymer science and drug carrier technologies have promulgated the development of novel drug carriers such as bioadhesive microspheres that have boosted the use of "bioadhesion" in drug delivery. This article presents the spectrum of potential applications of bioadhesive microspheres in controlled drug delivery ranging from the small molecules, to peptides, and to the macromolecular drugs such as proteins, oligonucleotides and even DNA. The development of mucus or cell-specific bioadhesive polymers and the concepts of cytoadhesion and bioinvasion provide unprecedented opportunities for targeting drugs to specific cells or intracellular compartments. Developments in the techniques for in vitro and in vivo evaluation of bioadhesive microspheres have also been discussed.
Publisher: Oxford University Press (OUP)
Date: 06-07-2018
Publisher: American Astronomical Society
Date: 11-09-2015
Publisher: Elsevier BV
Date: 06-1989
DOI: 10.1016/0013-4694(89)90229-0
Abstract: Somatosensory evoked potentials to electrical stimulation of muscle and cutaneous afferents from the foot were recorded in normal human subjects using multiple channels centred on the vertex and referenced to the contralateral earlobe. Low-threshold muscle afferents were selectively activated by an insulated microelectrode inserted percutaneously at the motor point of abductor hallucis. Low-threshold cutaneous and joint afferents of the hallux or second toe were stimulated with ring electrodes. The posterior tibial and sural nerves were stimulated at the ankle through surface electrodes. The cerebral distribution of the initial cortical response (N33-P40) to stimulation of muscle afferents largely paralleled that to stimulation of its parent nerve, the posterior tibial nerve (which contains afferents of muscle, cutaneous and joint origin). They were maximal slightly posterior and ipsilateral to the vertex. The cutaneous-joint afferent projection from the hallux paralleled that from the sural nerve and both were less lateralized than the tibial and abductor hallucis projections.
Publisher: Oxford University Press (OUP)
Date: 02-01-2019
Publisher: Elsevier BV
Date: 12-2002
Publisher: EDP Sciences
Date: 11-2018
DOI: 10.1051/0004-6361/201833183
Abstract: Using high-resolution data of the 12 CO and 13 CO ( J = 1 – 0) line emission from the Mopra Southern Galactic Plane CO Survey in conjunction with neutral hydrogen observations from the Southern Galactic Plane Survey (SGPS) and mid-infrared Spitzer data, we have explored the large-scale environment of the supernova remnant Kes 41. On the basis of these data, we identified for the first time the parent cloud of Kes 41 in its whole extension and surveyed the HII regions, masers, and the population of massive young stellar objects in the cloud. The whole unveiled giant cloud, located at the kinematic distance of 12.0 ± 3.6 kpc, whose average total mass and size are ~10–30 × 10 5 M ⊙ and ~ 26′, also shines in γ -rays, as revealed by the Large Area Telescope on board the Fermi satellite. We determined a high average proton density ~500–1000 cm −3 in the large molecular complex, of which protons from the neutral atomic and ionised gases comprise only ~15%.
Start Date: 2016
End Date: 2016
Funder: Australian Research Council
View Funded ActivityStart Date: 2015
End Date: 2015
Funder: Australian Research Council
View Funded Activity