ORCID Profile
0000-0001-6685-5464
Current Organisation
Hong Kong University of Science and Technology
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Publisher: Wiley
Date: 03-07-2021
Abstract: Chromophores that exhibit aggregation‐induced emission (i.e., aggregation‐induced emission luminogens [AIEgens]) emit intense fluorescence in their aggregated states, but show negligible emission as discrete molecular species in solution due to the changes in restriction and freedom of intramolecular motions. As solvent‐swollen quasi‐solids with both a compact phase and a free space, gels enable manipulation of intramolecular motions. Thus, AIE‐active gels have attracted significant interest owing to their various distinctive properties and promising application potential. Herein, a comprehensive overview of AIE‐active gels is provided. The fabrication strategies employed are detailed, and the applications of AIEgens are summarized. In addition, the gel functions arising from the AIE moieties are revealed, along with their structure–property relationships. Furthermore, the applications of AIE‐active gels in erse areas are illustrated. Finally, ongoing challenges and potential means to address them are discussed, along with future perspectives on AIE‐active gels, with the overall aim of inspiring research on novel materials and ideas.
Publisher: Wiley
Date: 04-10-2021
Abstract: Microscopic control of macroscopic phenomena is one of the core subjects in materials science. Particularly, the spatio‐temporal control of material behaviors through a non‐contact way is of fundamental importance but is difficult to accomplish. Herein, a strategy to realize remote spatio‐temporal control of luminescence behaviors is reported. A multi‐arm salicylaldehyde benzoylhydrazone‐based aggregation‐induced emission luminogen (AIEgen)/metal‐ion system, of which the fluorescence can be gated by the UV irradiation with time dependency, is developed. By changing the metal‐ion species, the fluorescence emission and the intensity can also be tuned. The mechanism of the UV‐mediated fluorescence change is investigated, and it is revealed that a phototriggered aggregation‐induced emission (PTAIE) process contributes to the behaviors. The AIEgen is further covalently integrated into a polymeric network and the formed gel/metal‐ion system can achieve laser‐mediated mask‐free writing enabled by the PTAIE process. Moreover, by further taking advantage of the time‐dependent self‐healing property of hydrazone‐based dynamic covalent bond, transformable 4D soft patterns are generated. The findings and the strategy increase the ways to manipulate molecules on the supramolecule or aggregate level. They also show opportunities for the development of controllable smart materials and expand the scope of the materials in advanced optoelectronic applications.
Publisher: Wiley
Date: 23-04-2023
Abstract: Multifunctional nanoaggregates are widely used in cancer phototheranostics. However, it is challenging to construct their multifunctionality with a single component, and deliver them rapidly and efficiently without complex modifications. Herein, a NIR‐absorbing small molecule named TBT‐2(TP‐DPA) is designed and certify its theranostic potentials. Then, their nanoaggregates, which are simply encapsulated by DSPE‐PEG, demonstrate a photothermal efficiency of 51% while keeping a high photoluminescence quantum yield in the NIR region. Moreover, the nanoaggregates can be excited and delivered by an 808 nm pulse laser to solid tumors within only 40 min. The delivery efficiency and theranostic efficacy are better than that of the traditional enhanced permeability and retention (EPR) effect (generally longer than 24 hours). This platform is first termed as the photoinduced thermoacoustic (PTA) process, and confirm its application requires both NIR‐responsive materials and pulse laser irradiation. This study not only inspires the design of multifunctional nanoaggregates, but also offers a feasible approach to their fast delivery. The platform reported here provides a promising prospect to boost the development of multifunctional theranostic drugs and maximize the efficacy of used medicines for their clinical applications.
Publisher: AIP Publishing
Date: 08-2022
DOI: 10.1063/5.0101373
Abstract: Fluorescent supramolecular gel is a large group in luminescent gels. In the scope of practical applications, excellent stability and robust luminescence are complementary and indispensable for high-performance fluorescent supramolecular gels. Therefore, in this Perspective, the proceedings of precursor explorations of stabilizing and boosting the luminescence behavior of the gels will be briefly summarized. The challenges and possible development frontiers will also be pondered to inspire future scientific research achievements.
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D0QM01004A
Abstract: A facile synthesized AIE bioprobe was developed to detect peroxynitrite sensitively and specifically. This bioprobe can realize both in vitro ONOO − detection and in vivo visualization of inflammation.
No related grants have been discovered for Huilin Xie.