ORCID Profile
0000-0002-0019-5851
Current Organisations
Fiona Stanley Hospital
,
Institut régional du Cancer de Montpellier
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Publications
Ovarian-Adnexal Reporting and Data System for Magnetic Resonance Imaging (O-RADS MRI): Genesis and Future Directions.
Publisher: SAGE Publications
Date: 16-10-2022
DOI: 10.1177/08465371221121738
Abstract: Imaging plays an important role in characterizing and risk-stratifying commonly encountered adnexal lesions. Recently, the American College of Radiology (ACR) released the Ovarian-Adnexal Reporting and Data System (O-RADS) for ultrasound and subsequently for magnetic resonance imaging (MRI). The goal of the recently developed ACR O-RADS MRI risk stratification system is to improve the quality of imaging reports as well as the reproducibility of evaluating adnexal lesions on MRI. This review focuses on exploring this new system and its future refinements.
Triple rule-out computed tomography angiography: Evaluation of acute chest pain in COVID-19 patients in the emergency department
Publisher: Baishideng Publishing Group Inc.
Date: 28-08-2022
Comparison of Bayesian analysis and PET-CT findings with respect to likelihood of malignancy in solid and subsolid solitary pulmonary nodules.
Publisher: Independent Medical Trust
Date: 10-11-2019
DOI: 10.29309/TPMJ/2019.26.11.3674
Abstract: Objectives: To determine whether Bayesian Analysis (BA) predicts malignancy with similar specificity and sensitivity values in both subgroups of solitary pulmonary nodules (SPNs) and to compare PET-CT findings in solid and subsolid subgroups of PET-CT scanned SPNs. Study Design: An observational study. Setting: Department of Chest Diseases, Ankara Chest Diseases and Chest Surgery Training and Research Hospital. Period: February 2013 to February 2016. Materials and Methods: 156 patients with SPNs and whose histopathological diagnosis confirmed by fiberoptic bronchoscopy biopsy, transthoracic tru-cut biopsy or surgical methods were evaluated retrospectively. BA and PET-CT findings of nodules were evaluated. Results: 73.3% of male patients and 80% of females with subsolid SPN were diagnosed malignant. BA was statistically significantly found to be consistent with definitive diagnosis in Kappa compliance analysis in solid and nonsolid nodules (p .005 kappa = 0.604 p = 0.023 kappa = 0.358). The sensitivity of BA in solid and subsolid nodules was 63.6% and 80%, respectively, while their specificity was 93.4% and 73%, respectively. Positive predictive values (PPVs) were found to be 84% in solid nodules and 36% in subsolid nodules. Negative predictive values (NPVs) were calculated as 83% in solid nodules and 95% in subsolid nodules. In the patients with SPN included in our study, Kappa compliance analysis was performed separately in the solid and subsolid subgroups of patients who underwent PET-CT. When the cutoff value of Kappa compliance analysis in solid nodules was taken 2.5, definitive diagnosis and suvmax uptake were found to be statistically consistent (p .005 kappa = 0.638). When the cutoff value of Kappa compliance analysis in subsolid nodules was taken to be 2.5 as malignancy value, definitive diagnosis and suvmax uptake were found to be statistically consistent as in subgroup (p=0,011 kappa=0,399). When we took PET-CT suvmax cutoff value as 2.5, sensitivity uptake and specificity of PET were found in solid nodules, to be 68.4% and 93.1%, respectively. PPV was 86.7% and NPV was 82%. The sensitivity and specificity values of subsolid subgroup were 70% and 75% respectively, whereas the PPVs and NPVs were 50% and 87.5%, respectively. Conclusion: In subsolid SPNs, as in BA, PET-CT seems to be more reliable when used exclusively in malignancy exclusion. Although a significant suvmax cut-off value was determined for malignancy, the PPV of PET-CT is lower than that of solid SPNs.
Breast arterial calcifications as an indicator of atherosclerotic cardiovascular disease: comparative analysis of coronary computed tomography scoring systems and carotid intima-media thickness
Publisher: AME Publishing Company
Date: 2022
DOI: 10.21037/QIMS-21-98
Doppler ultrasonography criteria of superior mesenteric artery stenosis
Publisher: Wiley
Date: 29-01-2019
DOI: 10.1002/JCU.22695
Abstract: The techniques mostly used for the diagnosis of superior mesenteric artery (SMA) stenosis are computed tomography angiography (CTA), and magnetic resonance angiography. We aimed to evaluate color-coded Doppler Ultrasonography (CDUS) for the detection of SMA stenoses and to determine Doppler criteria. We identified retrospectively 65 patients with CTA images of SMA stenosis and examined them with CDUS for the Doppler measurement of SMA peak systolic flow velocity (PSV), end-diastolic velocity (EDV), and mesenterico-aortic ratio (MAR). Results were analyzed with receiver-operating characteristic curve analysis. The optimal threshold values for determining 50%-69% SMA stenoses were PSV >280 cm/s, EDV >45 cm/s, and MAR >3.6. For identifying 70%-99% SMA stenoses, they were PSV >395 cm/s, EDV >74 cm/s, and MAR >3.6. CDUS is a convenient method with high accuracy for identifying SMA stenosis. PSV yielded better results than EDV and MAR.
MRI in Evaluation of Solitary Pulmonary Nodules.
Publisher: AVES Publishing Co.
Date: 10-01-2019
Computed Tomography–Guided Methylene Blue Labeling Prior to Thoracoscopic Resection of Small Deeply Placed Pulmonary Nodules. Do We Really Need Palpation?
Publisher: Georg Thieme Verlag KG
Date: 28-01-2017
Abstract: Background Video-assisted thoracic surgery (VATS) is widely used for thoracic surgery operations, and day by day it becomes routine for the excision of undetermined pulmonary nodules. However, it is sometimes hard to reach millimetric nodules through a VATS incision. Therefore, some additional techniques were developed to reach such nodules little in size and which are settled on a challenging localization. In the literature, coils, hook wires, methylene blue, lipidol, and barium staining, and also ultrasound guidance were described for this aim. Herein we discuss our experience with CT-guided methylene blue labeling of small, deeply located pulmonary nodules just before VATS excision. Method From April 2013 to October 2016, 11 patients with millimetric pulmonary nodules (average 8, 7 mm) were evaluated in our clinic. For all these patients who had strong predisposing factors for malignancy, an 18F-FDG PET-CT scan was also performed. The patients whose nodules were decided to be excised were consulted the radiology clinic. The favorable patients were taken to CT room 2 hours prior to the operation, and CT-guided methylene blue staining were performed under sterile conditions. Results Mean nodule size of 11 patients was 8.7 mm (6, 2–12). Mean distance from the visceral pleural surface was 12.7 mm (4–29.3). Four of the nodules were located on the left (2 upper lobes, 2 lower lobes), and seven of them were on the right (four lower lobes, two upper lobes, one middle lobe). The maximum standardized uptake values (SUV max) on 18F-FDG PET/CT scan ranged between 0 and 2, 79. Conclusion CT-guided methylene blue staining of millimetric deeply located pulmonary nodules is a safe and feasible technique that helps surgeon find these undetermined nodules by VATS technique without any need of digital palpation.
Treatment Outcome of 227 Patients with Sinonasal Adenoid Cystic Carcinoma (ACC) after Intensity Modulated Radiotherapy and Active Raster-Scanning Carbon Ion Boost: A 10-Year Single-Center Experience
Publisher: MDPI AG
Date: 11-2019
Abstract: We aimed to evaluate the treatment outcome of primary and postoperative bimodal radiotherapy (RT) including intensity modulated photon radiotherapy (IMRT) and carbon ion radiotherapy (CIRT) for sinonasal adenoid cystic carcinoma (ACC) patients. Medical records of 227 consecutive patients who received either a primary (n = 90, 40%) or postoperative (n = 137, 60% R2, n = 86, 63%) IMRT with doses between 48 and 56 Gy in 1.8 or 2 Gy fractions and active raster-scanning carbon ion boost with 18 to 24 Gy (RBE, relative biological effectiveness) in 3 Gy (RBE) fractions between 2009 and 2019 up to a median total dose of 80 Gy (EQD2, equivalent dose in 2 Gy single dose fractions, range 71–80 Gy) were reviewed. Results: Median follow-up was 50 months. In univariate and multivariate analysis, no significant difference in local control (LC) could be shown between the two treatment groups (p = 0.33). Corresponding 3-year LC rates were 79% for primary bimodal RT and 82% for postoperative bimodal RT, respectively. T4 stage (p = 0.002) and solid histology (p = 0.005) were identified as independent prognostic factors for decreased LC. Significant worse long-term treatment tolerance was observed for postoperatively irradiated patients with 17% vs. 6% late grade 3 toxicity (p 0.001). Primary radiotherapy including IMRT and carbon ion boost for dose-escalation results in adequate LC with less long-term grade 3 toxicity compared to postoperative bimodal radiotherapy in sinonasal ACC patients. The high rate of macroscopic tumor disease in the postoperative group makes the interpretation of the beneficial results in LC for primary RT difficult.
Large German Multicenter Experience on the Treatment Outcome of 207 Patients With Adenoid Cystic Carcinoma of the Major Salivary Glands
Publisher: Frontiers Media SA
Date: 11-11-2020
Prognostic significance of metastasis-suppressor gene NM23 in gastric carcinoma
Publisher: SelSistem
Date: 29-07-2019
Prognosis of patients hospitalized with a diagnosis of COVID-19 pneumonia in a tertiary hospital in Turkey
Publisher: King Faisal Specialist Hospital and Research Centre
Date: 11-2021
DOI: 10.5144/0256-4947.2021.327
Abstract: SARS-CoV2/COVID-19 emerged in China and caused a global pandemic in 2020. The mortality rate has been reported to be between 0% and 14.6% in all patients. In this study, we determined the clinical and laboratory parameters of COVID-19 related morbidity and mortality in our hospital. Investigate the relationship between demographic, clinical, and laboratory parameters on COVID-19-related morbidity and mortality. Retrospective observational study. Tertiary care hospital. Patients diagnosed with COVID-19 pneumonia from March until the end of December were included in the study. The relationship between demographic, clinical, and laboratory parameters and the morbidity and mortality rates of patients diagnosed with COVID-19. 124 patients The mortality rate was 9.6% (12/124). Coronary artery disease ( P .0001) diabetes mellitus ( P =.04) fever ( .3°C) at presentation ( P =.04) hypertension ( P .0001), and positive smoking history ( P .0001) were significantly associated with mortality. Patients who died were older, had a higher comorbid disease index, pneumonia severity index, fasting blood glucose, baseline serum creatinine, D-dimer, and had lower baseline haemoglobin, SaO 2 , percentage of lymphocyte counts and diastolic blood pressure. Patients admitted to the ICU were older, had a higher comorbidity disease index, pneumonia severity index, C-reactive protein, WBC, D-dimer, creatinine, number of antibiotics used, longer O 2 support duration, lower hemoglobin, lymphocyte (%), and baseline SaO 2 (%). Our results were consistent with much of the reported data. We suggest that the frequency, dosage, and duration of steroid treatment should be limited. Low patient number, uncertain reason of mortality, no standard treatment regimen, limited treatment options, like ECMO. None.
Related Organisations
Ankara Atatürk Göğüs Hastalıkları Ve Göğüs Cerrahisi Eğitim Ve Araştırma Hastanesi
Location: Turkey
University Of Health Sciences- Yuksek Ihtisas Training And Research Hospital
Location: Turkey
Related Funding Activities
No related grants have been discovered for Suzan Bahadir.