ORCID Profile
0000-0001-9849-2928
Current Organisation
Curtin University
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Publisher: European Respiratory Society
Date: 05-09-2021
Publisher: European Respiratory Society
Date: 05-09-2021
Publisher: Informa UK Limited
Date: 12-2022
DOI: 10.1080/09593985.2022.2148146
Abstract: Increasing physical activity in daily life (PADL) in chronic obstructive pulmonary disease (COPD), mainly in short-term training programs, is still a challenge. The combination of functional exercises with aerobic and resistance training may be a strategy to improve PADL and limitations in activities of daily living (ADL) in COPD. To evaluated the short- and medium-term effects of the combination of functional exercises with aerobic and resistance training. Seventy-six patients were randomized into (1) functional training group who performed resistance and aerobic and functional exercises (2) conventional training group (CTG) who performed resistance and aerobic exercise or (3) usual care group who performed respiratory physiotherapy. Patients were evaluated for PADL (activity monitor), ADL limitations (London Chest Activity of Daily Living scale [LCADL]), functional exercise capacity (6-minute walk test [6MWT]), and peripheral muscle strength before and after eight weeks. Medium-term effects were evaluated 12 weeks after the training. There were no changes or differences between groups in PADL and in 6MWT post-intervention and 12 weeks post-training. Only CTG showed a reduction in the total score on LCADL scale after the intervention and increase at follow-up (score: 20 ± 8 17 ± 6 19 ± 8, pre-intervention, post-intervention, and 12 weeks post-training, respectively, Combined aerobic and resistance training with functional exercises failed to improve PADL and ADL limitations in COPD. Eight weeks of conventional training improved ADL. This, however, was not superior to the results from the other groups and was not sustained at medium-term 12 weeks post-training.
Publisher: SAGE Publications
Date: 2022
DOI: 10.1177/17534666221091179
Abstract: Although evidence suggests that physical exercise reduces systemic inflammation, at the plasma level, there are still contradictions in chronic obstructive pulmonary disease (COPD). In this sense, analysis of intracellular cytokines could clear off the effect of physical exercise on the inflammatory profile of these subjects. The aim was to evaluate the effect of physical training on cytokine expression in CD4+ T lymphocytes from subjects with COPD. This is a randomized controlled trial. Subjects with stable COPD were grouped into two groups, exercise and control. In total, 23 subjects with stable COPD were evaluated, of which 15 underwent aerobic strength training [physical exercise group (PEG)] and 8 underwent breathing exercises [respiratory physiotherapy group (RPG)]. Intracellular cytokines [interleukin (IL)-8, IL-13, IL-17, IL-6, IL-2, IL-10, and tumor necrosis factor alpha (TNF-α)] from CD4+ T lymphocytes were analyzed from peripheral blood through flow cytometry, before and after 8 weeks of intervention. The PEG and RPG groups had a mean age of 68 ± 5.96 and 72.25 ± 6.86 years and predicted forced expiratory volume in the first second (FEV 1 ) of 58.6 ± 15.99% and 39.75 ± 10.39%, respectively. It was possible to detect a significant reduction in IL-8 ( p = 0.0125) and an increase in IL-13 ( p = 0.0014) and an increase in TNF-α ( p 0.001) in both groups. Eight weeks of physical training, both peripheral and respiratory, were able to reduce concentrations of IL-8 and to increase IL-13, and TNF-α in CD4+ T lymphocytes in subjects with stable COPD. The findings reinforce the benefits of interventions in subjects with COPD, revealing data not previously investigated.
Publisher: JMIR Publications Inc.
Date: 23-12-2022
Abstract: ung or head and neck cancers are known for their high prevalence and mortality rates. Chemotherapy and radiotherapy are usually recommended as cancer treatment for these malignancies however, they can negatively impact both the physical and mental status of patients. Hence, it is reasonable to consider resistance and aerobic exercise training to prevent these negative health outcomes. Further, several factors prevent patients from attending outpatient exercise training programs, and, therefore, a semisupervised home-based exercise training program may be seen as a well-accepted alternative. he aim of this study will be to investigate the effects of a semisupervised home-based exercise training program on physical performance, body composition, and self-reported outcomes changes in the initial cancer treatment dose prescribed number of hospitalizations at 3, 6, and 9 months and 12-month survival in people with primary lung or head and neck cancer. articipants will be randomly allocated to the training group (TG) or control group (CG). The TG will undergo semisupervised home-based resistance and aerobic exercise training throughout their cancer treatment. The resistance training will be performed using elastic bands (TheraBand) twice a week. The aerobic training (ie, brisk walk) will be performed for at least 20 minutes per day outdoors. The equipment and tools used during the training sessions will be provided. This intervention will start the week before treatment commencement, will be performed throughout the duration of the treatment, and will continue for 2 weeks after treatment completion. The CG will undergo usual care (ie, cancer treatment with no formal exercise prescription). Assessments will take place 2 weeks before the beginning of the usual cancer treatment and 2 weeks after treatment completion. The measures of physical function (peripheral muscle strength, functional exercise capacity, and physical activity), body composition, and self-reported outcomes (symptoms of anxiety and depression, health-related quality of life, and symptoms related to the disease and treatment) will be collected. We will report on any change in the initial cancer treatment dose prescribed number of hospitalizations at 3, 6, and 9 months and 12-month survival. n February 2021, the clinical trial registration was approved. Recruitment and data collection for the trial are ongoing (as of April 2023, 20 participants had already been randomized), and findings of this study are likely to be published late in 2024. his exercise training as a complementary treatment for patients with cancer is likely to promote positive effects on the health outcomes assessed, over and above any change in the CG, and prevent the reduction of initial cancer treatment dose prescribed. If these positive effects are shown, they will likely impact long-term outcomes such as hospitalizations and 12-month survival. razilian Clinical Trials Registry (ReBEC) RBR-5cyvzh9 ensaiosclinicos.gov.br/rg/RBR-5cyvzh9. RR1-10.2196/43547
Publisher: Springer Science and Business Media LLC
Date: 12-2019
DOI: 10.1186/S13063-019-3780-Y
Abstract: Functional training has been shown to be a viable alternative for the elderly and patients with chronic obstructive pulmonary disease (COPD). However, whether the combination of this type of training with aerobic and resistance training, commonly performed in pulmonary rehabilitation (PR) programs, induces more pronounced effects on daily physical activities and functionality remains unclear. The aims of the study will be to evaluate the short-term and sustained effects of the combination of a functional circuit program with a training program consisting of aerobic and resistance exercise. In this randomized controlled trial, patients with COPD will be randomly assigned (1:1:1) to an 8-week training program to follow one of the three a priori defined groups: (I) resistance and aerobic and functional exercises, (II) a conventional program including only resistance and aerobic exercises, or (III) a usual care program. Patients will be evaluated before and upon completion of 8 weeks of training regarding physical activity in daily life (PADL) using an activity monitor (accelerometer), activities of daily living (London Chest Activity of Daily Living), functional exercise capacity (6-minute walk test), and muscle strength (dynamometry). Additionally, the sustained effects of the interventions will be evaluated 22 weeks after commencing the study. The inclusion of a protocol of functional physical training in the training conventionally performed by patients with COPD as an alternative to increase PADL and functionality may provide subsidies for the treatment of these patients, representing an advance and impacting on the physical training of patients with COPD. Brazilian Clinical Trials Registry (ReBEC) ID: RBR-3zmh3r . Registered: March 7, 2018.
Publisher: European Respiratory Society
Date: 04-09-2022
Publisher: Informa UK Limited
Date: 10-2022
DOI: 10.2147/PPA.S367088
Publisher: Elsevier BV
Date: 11-2020
Publisher: European Respiratory Society
Date: 05-09-2021
Publisher: Universidade Estadual de Maringa
Date: 12-05-2016
DOI: 10.4025/JPHYSEDUC.V27I1.2722
Abstract: O objetivo deste estudo foi analisar os efeitos do treinamento resistido com tubos elásticos e aparelhos de musculação sobre qualidade de vida e dispneia em pacientes com doença pulmonar obstrutiva crônica (DPOC). Os participantes foram alocados em dois grupos: treinamento com tubos elásticos (GTE, n=9) e convencional (GRC, n=10). Força isométrica foi mensurada em cinco exercícios, e qualidade de vida (CRQ) e nível de dispneia (MRC) foram avaliados por questionários. As variáveis força isométrica e MRC variaram significantemente nos dois grupos, enquanto o domínio dispneia de CRQ apresentou diferença entre os momentos (p ,05) apenas para GRC. Flexão de ombro e de cotovelo apresentaram correlação negativa e significante com a variável MRC (p ,05) para GRC. As duas intervenções foram benéficas para o aumento da força e da redução da pontuação em MRC, com aumento da força de membros superiores correlacionado à redução da sensação de dispneia nos pacientes com DPOC.
Publisher: Elsevier BV
Date: 11-2018
Publisher: Oxford University Press (OUP)
Date: 13-10-2020
DOI: 10.1093/PTJ/PZAA186
Publisher: JMIR Publications Inc.
Date: 24-05-2023
DOI: 10.2196/43547
Abstract: Lung or head and neck cancers are known for their high prevalence and mortality rates. Chemotherapy and radiotherapy are usually recommended as cancer treatment for these malignancies however, they can negatively impact both the physical and mental status of patients. Hence, it is reasonable to consider resistance and aerobic exercise training to prevent these negative health outcomes. Further, several factors prevent patients from attending outpatient exercise training programs, and, therefore, a semisupervised home-based exercise training program may be seen as a well-accepted alternative. The aim of this study will be to investigate the effects of a semisupervised home-based exercise training program on physical performance, body composition, and self-reported outcomes changes in the initial cancer treatment dose prescribed number of hospitalizations at 3, 6, and 9 months and 12-month survival in people with primary lung or head and neck cancer. Participants will be randomly allocated to the training group (TG) or control group (CG). The TG will undergo semisupervised home-based resistance and aerobic exercise training throughout their cancer treatment. The resistance training will be performed using elastic bands (TheraBand) twice a week. The aerobic training (ie, brisk walk) will be performed for at least 20 minutes per day outdoors. The equipment and tools used during the training sessions will be provided. This intervention will start the week before treatment commencement, will be performed throughout the duration of the treatment, and will continue for 2 weeks after treatment completion. The CG will undergo usual care (ie, cancer treatment with no formal exercise prescription). Assessments will take place 2 weeks before the beginning of the usual cancer treatment and 2 weeks after treatment completion. The measures of physical function (peripheral muscle strength, functional exercise capacity, and physical activity), body composition, and self-reported outcomes (symptoms of anxiety and depression, health-related quality of life, and symptoms related to the disease and treatment) will be collected. We will report on any change in the initial cancer treatment dose prescribed number of hospitalizations at 3, 6, and 9 months and 12-month survival. In February 2021, the clinical trial registration was approved. Recruitment and data collection for the trial are ongoing (as of April 2023, 20 participants had already been randomized), and findings of this study are likely to be published late in 2024. This exercise training as a complementary treatment for patients with cancer is likely to promote positive effects on the health outcomes assessed, over and above any change in the CG, and prevent the reduction of initial cancer treatment dose prescribed. If these positive effects are shown, they will likely impact long-term outcomes such as hospitalizations and 12-month survival. Brazilian Clinical Trials Registry (ReBEC) RBR-5cyvzh9 ensaiosclinicos.gov.br/rg/RBR-5cyvzh9. PRR1-10.2196/43547
Publisher: University Nove de Julho
Date: 30-03-2018
DOI: 10.5585/CONSSAUDE.V17N1.7460
Abstract: Introduo: O tabagismo provoca efeitos deletrios a sade afetando o estado de sade geral do in duo. Neste contexto, torna-se indispensvel avaliao da influncia do fumo nas variveis respiratrias e na capacidade funcional de tabagistas. Objetivo: Analisar a influncia de variveis espiromtricas na capacidade de exerccio de in duos tabagistas. Mtodos: Estudo transversal com 78 in duos tabagistas, idade entre 40 e 60 anos, no qual foram avaliadas a funo pulmonar (espirometria), a capacidade funcional (teste de caminhada de seis minutos-TC6) e a transportabilidade mucociliar nasal (teste do tempo de transporte da sacarina-TTS). Resultados: As variveis espiromtricas apresentaram correlao positiva significativa com o TC6 e o TTS no apresentou correlao com o TC6. Concluso: A funo pulmonar tem correlao com a capacidade funcional, no entanto o TTS no apresenta essa correlao em in duos tabagistas leves.
Publisher: Elsevier BV
Date: 05-2023
Publisher: European Respiratory Society
Date: 28-09-2019
Publisher: European Respiratory Society
Date: 07-09-2020
Publisher: European Respiratory Society
Date: 28-09-2019
Publisher: European Respiratory Society
Date: 28-09-2019
Publisher: European Respiratory Society
Date: 07-09-2020
Publisher: Informa UK Limited
Date: 11-2020
DOI: 10.2147/COPD.S268955
Publisher: Elsevier BV
Date: 05-2022
Publisher: European Respiratory Society
Date: 07-09-2020
Publisher: European Respiratory Society
Date: 07-09-2020
Location: Brazil
Start Date: 2016
End Date: 2016
Funder: Conselho Nacional de Desenvolvimento Científico e Tecnológico
View Funded ActivityStart Date: 2021
End Date: 2023
Funder: Fundação de Amparo à Pesquisa do Estado de São Paulo
View Funded ActivityStart Date: 2017
End Date: 2019
Funder: Fundação de Amparo à Pesquisa do Estado de São Paulo
View Funded ActivityStart Date: 2015
End Date: 2016
Funder: Conselho Nacional de Desenvolvimento Científico e Tecnológico
View Funded ActivityStart Date: 2017
End Date: 2019
Funder: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
View Funded Activity