ORCID Profile
0000-0002-9593-4652
Current Organisations
Johns Hopkins Bloomberg School of Public Health
,
Johns Hopkins School of Medicine
,
Université de Montréal
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Publisher: Springer Science and Business Media LLC
Date: 05-06-2012
Publisher: IEEE
Date: 11-2013
Publisher: Public Library of Science (PLoS)
Date: 18-09-2014
Publisher: Association for Research in Vision and Ophthalmology (ARVO)
Date: 29-05-2014
Publisher: Springer Science and Business Media LLC
Date: 30-03-2020
Publisher: Elsevier BV
Date: 08-2013
Publisher: Springer Science and Business Media LLC
Date: 06-04-2016
DOI: 10.1038/NCOMMS11008
Abstract: Myopia is the most common human eye disorder and it results from complex genetic and environmental causes. The rapidly increasing prevalence of myopia poses a major public health challenge. Here, the CREAM consortium performs a joint meta-analysis to test single-nucleotide polymorphism (SNP) main effects and SNP × education interaction effects on refractive error in 40,036 adults from 25 studies of European ancestry and 10,315 adults from 9 studies of Asian ancestry. In European ancestry in iduals, we identify six novel loci ( FAM150B-ACP1 , LINC00340 , FBN1 , DIS3L-MAP2K1 , ARID2-SNAT1 and SLC14A2 ) associated with refractive error. In Asian populations, three genome-wide significant loci AREG , GABRR1 and PDE10A also exhibit strong interactions with education ( P .5 × 10 −5 ), whereas the interactions are less evident in Europeans. The discovery of these loci represents an important advance in understanding how gene and environment interactions contribute to the heterogeneity of myopia.
Publisher: Oxford University Press (OUP)
Date: 07-03-2013
DOI: 10.1093/HMG/DDT116
Publisher: Springer Science and Business Media LLC
Date: 31-08-2014
DOI: 10.1038/NG.3087
Publisher: Springer Science and Business Media LLC
Date: 29-05-2013
DOI: 10.1038/NG0613-712B
Publisher: Springer Science and Business Media LLC
Date: 04-11-2014
Publisher: Wiley
Date: 26-10-2016
DOI: 10.1002/GEPI.21936
Publisher: Springer Science and Business Media LLC
Date: 10-02-2013
DOI: 10.1038/NG.2554
Publisher: American Medical Association (AMA)
Date: 2014
Location: United States of America
No related grants have been discovered for Robert Wojciechowski.