ORCID Profile
0000-0002-7498-2954
Current Organisations
Royal College of Paediatrics and Child Health
,
Ospedale San Raffaele
,
Academy of Medicine of Malaysia
,
International Medical University
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Related Links
Publications
Feels Not Right Stabbing a Child
Publisher: Elsevier BV
Date: 07-2018
Introducing clinical ethics consultation service in Malaysia: A SWOT analysis
Publisher: SAGE Publications
Date: 03-2019
Abstract: Clinical ethics consultation service remains undeveloped in developing countries. It is recognised that its introduction poses challenges. Malaysia, a multicultural society with erse religions, values and perceptions further complicate the introduction of formal clinical ethics consultation service. Clinicians attending a national congress workshop completed a Strengths–Weaknesses–Opportunities–Threats analysis. The aim was to gain insight into clinician’s expectations and promote initiatives leading to the introduction of clinical ethics consultation service. Clinicians agree that clinical ethics consultation service can improve quality of care, reduce healthcare costs and advocate for patients and providers. The analysis highlighted constraints in sufficient critical mass of relevant expertise and restricted opportunities for training. The opportunities lie in education, curriculum development and availability of dedicated proponents. Cultural barriers, limited resources, lack of awareness, differences in opinions, fear of litigation and destructive influence of social media are seen as threats to the introduction of clinical ethics consultation service. This study illustrates the value of involving stakeholders when introducing clinical ethics consultation service formally. The issues identified will inform the strategic directions for the delivery of clinical ethics consultation service at a national level.
Nkx2-5+Islet1+ Mesenchymal Precursors Generate Distinct Spleen Stromal Cell Subsets and Participate in Restoring Stromal Network Integrity
Publisher: Elsevier BV
Date: 04-2013
Tumor-Targeted Interferon-α Delivery by Tie2-Expressing Monocytes Inhibits Tumor Growth and Metastasis
Publisher: Elsevier BV
Date: 10-2008
DOI: 10.1016/J.CCR.2008.09.004
Abstract: The use of type I interferons (IFNs) in cancer therapy has been limited by ineffective dosing and significant toxicity. Here, we exploited the tumor-homing ability of proangiogenic Tie2-expressing monocytes (TEMs) to deliver IFN-alpha to tumors. By transplanting hematopoietic progenitors transduced with a Tie2 promoter/enhancer-driven Ifna1 gene, we turned TEMs into IFN-alpha cell vehicles that efficiently targeted the IFN response to orthotopic human gliomas and spontaneous mouse mammary carcinomas and obtained significant antitumor responses and near complete abrogation of metastasis. TEM-mediated IFN-alpha delivery inhibited tumor angiogenesis and activated innate and adaptive immune cells but did not impair myelopoiesis and wound healing detectably. These results illustrate the therapeutic potential of gene- and cell-based IFN-alpha delivery and should allow the development of IFN treatments that more effectively treat cancer.
Perception and practices regarding e-cigarettes among health sciences students and health professionals: protocol of a systematic review of world literature
Publisher: INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols
Date: 16-11-2020
Related Organisations
Royal College Of Paediatrics And Child Health
Location: United Kingdom of Great Britain and Northern Ireland
Children's Mercy Hospital In Affliation With University Of Missouri-Kansas City
Location: United States of America
Related Funding Activities
No related grants have been discovered for Erwin Khoo.