ORCID Profile
0000-0002-8029-7187
Current Organisation
Universidad de La Sabana
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Publisher: Springer Science and Business Media LLC
Date: 22-06-2021
DOI: 10.1038/S41579-021-00578-9
Abstract: An optimal antimicrobial dose provides enough drug to achieve a clinical response while minimizing toxicity and development of drug resistance. There can be considerable variability in pharmacokinetics, for ex le, owing to comorbidities or other medications, which affects antimicrobial pharmacodynamics and, thus, treatment success. Although current approaches to antimicrobial dose optimization address fixed variability, better methods to monitor and rapidly adjust antimicrobial dosing are required to understand and react to residual variability that occurs within and between in iduals. We review current challenges to the wider implementation of antimicrobial dose optimization and highlight novel solutions, including biosensor-based, real-time therapeutic drug monitoring and computer-controlled, closed-loop control systems. Precision antimicrobial dosing promises to improve patient outcome and is important for antimicrobial stewardship and the prevention of antimicrobial resistance.
Publisher: MDPI AG
Date: 16-09-2022
Abstract: Purpose: To measure the preliminary effectiveness of a strategy to promote healthy lifestyle habits in schoolchildren, aged 6 to 12 years, living in the Andean region of Colombia, 2018–2021. Design and Methods: This is a Nursing Methodological Research, developed in phases: (1) Context and schoolchildren characterization (2) Strategy design guided by the Whittemore and Grey criteria and the Bronfenbrenner ecological conceptual model (3) Strategy validation with 11 experts (4) Trial to evaluate preliminary effectiveness. We applied the strategy in seven different schools with the educational community including 955 schoolchildren between 6 and 12 years of age, 551 parents, 130 teachers and 7 members of the food staff. Results: Our health promotion strategy “Prosalud” has five components: citizenship feeding and nutrition, physical activity, and rest environment protection, and directing one’s own life. It includes all the participants of the educational community. Conclusions: According to experts, the health promotion strategy “Prosalud” is valid to help promoting healthy lifestyle habits among schoolchildren. This strategy demonstrates its preliminary effectiveness in a group of school children from 6 to 12 years of age, their parents, teachers, and school food staff, in the Andean region of Colombia.
Publisher: Editorial Pontificia Universidad Javeriana
Date: 07-11-2019
DOI: 10.11144/JAVERIANA.RGPS18-37.PSEM
Abstract: Se ha demostrado que el medio ambiente es definitivo en el desarrollo de los niños y niñas en edad escolar, y que este debe ser considerado para promover su salud. El presente estudio analizó la literatura mundial sobre promoción de la salud escolar en relación con el medio ambiente, mediante una búsqueda integradora que incluyó artículos indexados bajo los descriptores salud escolar, promoción de la salud y medio ambiente, entre 2014 y 2017, sin límites idiomáticos ni geográficos. De las 106 referencias reportadas, 40 que cumplieron criterios de selección se reportan con un análisis bibliométrico, la clasificación de ambiente, el nivel de evidencia y las categorías según su contenido. Aunque la evidencia reportada es débil, se ratifica que la promoción de la salud escolar se relaciona estrechamente con el medio ambiente en niveles que van desde el personal hasta el cultural y social. Los contenidos de esta literatura se agrupan en seis categorías: interacciones y comportamiento ciudadano, ambiente e hidratación, ambiente y actividad física, manejar condiciones especiales de salud, ambiente y nutrición, y políticas que promueven la salud en la escuela.
No related grants have been discovered for Beatriz Sánchez Herrera.