ORCID Profile
0000-0002-9116-2341
Current Organisation
UNSW Sydney
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Publisher: Elsevier BV
Date: 04-2021
Publisher: American Chemical Society (ACS)
Date: 19-02-2020
Abstract: Nanoprobes with biocompatibility and strong fluorescence have unique advantages in tumor detection and diagnosis. A nanoparticle with dual fluorescent signals for detecting and imaging of tumor cells was prepared, in which the outer layer of the particle is a hyaluronic acid-modified molecule with aggregation-induced emission properties, and the inner content is the boron-dipyrromethene (BODIPY) derivative. This nanoparticle has low critical micelle concentration, small size, and high fluorescence intensity. Cell imaging experiments showed that it is capable of stable cell imaging with a red and blue fluorescence conversion in response to cancer cells. Furthermore, the zebrafish experiment confirmed that it can be used for biological imaging. Nanoparticles with dual fluorescence response properties of the coated structure provide an effective way for detecting cancer cells.
Publisher: Wiley
Date: 25-08-2022
DOI: 10.1111/PHP.13505
Abstract: Nanogel is an important kind of biomaterials applied for wound dressings, drug delivery, medical diagnostics and biosensors. The properties of nanogels closely depend on the density of the crosslinking network. In this study, the role of triethanolamine (TEOA) in the effect on the crosslinking degree of nanogels based on poly(ethylene glycol) diacrylate (PEGDA) was investigated and illustrated. The effect of TEOA on the process of photopolymerization at 532 nm and properties of the nanogels was systematically investigated by using UV‐vis spectroscopy, FT‐IR spectroscopy, 1 H NMR, DLS, SEM, AFM and DSC. In brief, the double‐bond conversion of photopolymerization and the crosslinking degree of nanogels can be effectively regulated by TEOA.
Publisher: Springer Science and Business Media LLC
Date: 02-08-2022
Publisher: Wiley
Date: 19-05-2020
DOI: 10.1111/PHP.13249
Publisher: Elsevier BV
Date: 2021
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/C9TB02701G
Abstract: A novel nanoparticle as a fluorescent probe prepared through a photochemical cross-linking reaction between a tetraphenylethylene derivative with AIE properties and hyaluronic acid modified by methacrylic anhydride.
Publisher: Elsevier BV
Date: 10-2021
Location: Colombia
No related grants have been discovered for Jhair Peña.