ORCID Profile
0000-0002-6868-8994
Current Organisation
Catholic University of America
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Publisher: Copernicus GmbH
Date: 15-05-2023
DOI: 10.5194/EGUSPHERE-EGU23-10921
Abstract: Quantifying aerosol impacts on climate is an inherently multiscale problem since macro-scale impacts are determined by processes on the micro-scale. This poses unique modeling challenges, since these microscale processes lead to a continuously evolving aerosol mixing state, which is difficult to represent in large-scale models. This presentation will show how high-detail particle-resolved simulations can be used to predict the evolving aerosol mixing state on the regional scale. In contrast to traditional aerosol models that use bins or modes to represent the aerosol, the particle-resolved approach uses in idual computational particles that evolve in size and composition as the particles undergo aging processes in the atmosphere. This approach is therefore not limited by assumptions about particle composition within a given size range and can represent the full aerosol mixing state without simplifying assumptions. I will show results that illustrate the spatio-temporal evolution of aerosol mixing state, going beyond the traditional definitions of & #8220 externally& #8221 or & #8220 internally& #8221 mixed populations. I will conclude with a framework to synthesize a picture of the ambient aerosol from models and observations. This focuses on suitable metrics to quantify mixing state and s ling strategies to determine these metrics that are accessible for both models and observations. Together, these provide a unique opportunity for & #8220 getting the right answer for the right reasons& #8221 .&
Publisher: Informa UK Limited
Date: 03-09-2020
Immobilization of Antimicrobial Silver and Antioxidant Flavonoid as a Coating for Wound Dressing Materials
Publisher: Informa UK Limited
Date: 12-2019
DOI: 10.2147/IJN.S230214
Publisher: American Geophysical Union (AGU)
Date: 02-2021
DOI: 10.1029/2020EA001500
Publisher: Hindawi Limited
Date: 21-03-2019
DOI: 10.1155/2019/7382717
Abstract: Silver nanoparticles have attracted great interests widely in medicine due to its great characteristics of antibacterial activity. In this research, the antibacterial activity and biocompatibility of a topical gel synthesized from polyvinyl alcohol, chitosan, and silver nanoparticles were studied. Hydrogels with different concentrations of silver nanoparticles (15 ppm, 30 ppm, and 60 ppm) were evaluated to compare their antibacterial activity, nanoparticles’ sizes, and in vivo behaviors. The resulted silver nanoparticles in the hydrogel were characterized by TEM showing the nanoparticles’ sizes less than 22 nm. The in vitro results prove that the antibacterial effects of all of the s les are satisfied. However, the in vivo results demonstrate the significant difference among different hydrogels in wound healing, where hydrogel with 30 ppm shows the best healing rate.
Publisher: MDPI AG
Date: 10-08-2021
DOI: 10.3390/MA14164475
Abstract: The use of naturally occurring materials with antibacterial properties has gained a great interest in infected wound management. Despite being an abundant resource in Vietnam, chitosan and its derivatives have not yet been intensively explored for their potential in such application. Here, we utilized a local chitosan source to synthesize chitosan oligomers (OCS) using hydrogen peroxide (H2O2) oxidation under the microwave irradiation method. The effects of H2O2 concentration on the physicochemical properties of OCS were investigated through molecular weight, degree of deacetylation, and heavy metal contamination for optimization of OCS formulation. Then, the antibacterial inhibition was examined the minimum inhibitory concentration and minimum bactericidal concentration (MIC and MBC) of OCS-based materials were determined against common skin-inhabitant pathogens. The results show that the local Vietnamese chitosan and its derivative OCS possessed high-yield purification while the molecular weight of OCS was inversely proportional and proportional to the concentration of H2O2, respectively. Further, the MIC and MBC of OCS ranged from 3.75 to less than 15 mg/mL and 7.5–15 mg/mL, respectively. Thus, OCS-based materials induce excellent antimicrobial properties and can be attractive for wound dressings and require further investigation.
No related grants have been discovered for Khanh Ly.