ORCID Profile
0000-0002-8874-907X
Current Organisations
African Institute of Biomedical Science and Technology
,
University of Zimbabwe
,
World Health Organization
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Publisher: American Society for Microbiology
Date: 24-08-2020
DOI: 10.1128/JCM.01045-20
Abstract: HIV drug resistance (HIVDR) is a barrier to sustained virologic suppression in low- and middle-income countries (LMICs). Point mutation assays targeting priority drug resistance mutations (DRMs) are being evaluated to improve access to HIVDR testing. In a cross-sectional study (June 2018 to September 2019), we evaluated the diagnostic accuracy of a simple and rapid HIVDR assay (the pan-degenerate lification and adaptation [PANDAA] assay targeting the mutations K65R, K103NS, M184VI, Y181C, and G190A) compared to Sanger sequencing and next-generation sequencing (NGS).
Publisher: American Society for Microbiology
Date: 20-07-2022
DOI: 10.1128/JCM.00708-22
Publisher: Mary Ann Liebert Inc
Date: 10-2021
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 09-2019
Publisher: Public Library of Science (PLoS)
Date: 23-11-2021
DOI: 10.1371/JOURNAL.PONE.0260261
Abstract: Healthcare workers are disproportionately affected by COVID-19. In low- and middle- income countries, they may be particularly impacted by underfunded health systems, lack of personal protective equipment, challenging working conditions and barriers in accessing personal healthcare. In this cross-sectional study, occupational health screening was implemented at the largest public sector medical centre in Harare, Zimbabwe, during the “first wave” of the country’s COVID-19 epidemic. Clients were voluntarily screened for symptoms of COVID-19, and if present, offered a SARS-CoV-2 nucleic acid detection assay. In addition, measurement of height, weight, blood pressure and HbA1c, HIV and TB testing, and mental health screening using the Shona Symptom Questionnaire (SSQ-14) were offered. An interviewer-administered questionnaire ascertained client knowledge and experiences related to COVID-19. Between 27 th July and 30 th October 2020, 951 healthcare workers accessed the service 210 (22%) were tested for SARS-CoV-2, of whom 12 (5.7%) tested positive. Clients reported high levels of concern about COVID-19 which declined with time, and faced barriers including lack of resources for infection prevention and control. There was a high prevalence of largely undiagnosed non-communicable disease: 61% were overweight or obese, 34% had a blood pressure of 140/90mmHg or above, 10% had an HbA1c diagnostic of diabetes, and 7% had an SSQ-14 score consistent with a common mental disorder. Overall 8% were HIV-positive, with 97% previously diagnosed and on treatment. Cases of SARS-CoV-2 in healthcare workers mirrored the national epidemic curve. Implementation of comprehensive occupational health services during a pandemic was feasible, and uptake was high. Other comorbidities were highly prevalent, which may be risk factors for severe COVID-19 but are also important independent causes of morbidity and mortality. Healthcare workers are critical to combatting COVID-19 it is essential to support their physical and psychological wellbeing during the pandemic and beyond.
Publisher: MDPI AG
Date: 05-09-2023
DOI: 10.3390/V15091882
Publisher: Mary Ann Liebert Inc
Date: 11-2017
Location: Zimbabwe
Location: United States of America
Location: United States of America
No related grants have been discovered for Justen Manasa.