ORCID Profile
0000-0001-8927-5649
Current Organisation
University Of Strathclyde
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: MDPI AG
Date: 23-10-2020
DOI: 10.3390/BIOS10110153
Abstract: Antibiotic resistance has been cited by the World Health Organisation (WHO) as one of the greatest threats to public health. Mitigating the spread of antibiotic resistance requires a multipronged approach with possible interventions including faster diagnostic testing and enhanced antibiotic stewardship. This study employs a low-cost diagnostic sensor test to rapidly pinpoint the correct antibiotic for treatment of infection. The sensor comprises a screen-printed gold electrode, modified with an antibiotic-seeded hydrogel to monitor bacterial growth. Electrochemical growth profiles of the common microorganism, Escherichia coli (E. coli) (ATCC 25922) were measured in the presence and absence of the antibiotic streptomycin. Results show a clear distinction between the E. coli growth profiles depending on whether streptomycin is present, in a timeframe of ≈2.5 h (p 0.05), significantly quicker than the current gold standard of culture-based antimicrobial susceptibility testing. These results demonstrate a clear pathway to a low cost, phenotypic and reproducible antibiotic susceptibility testing technology for the rapid detection of E. coli within clinically relevant concentration ranges for conditions such as urinary tract infections.
Publisher: Elsevier BV
Date: 12-2017
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2SD00044J
Abstract: Pyocyanin production by Pseudomonas aeruginosa can be monitored using hyperspectral imaging and square wave voltammetry, with electrochemical impedance spectroscopy offering new avenues for low-cost sensing approaches to biofilm characterisation.
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1CC00936B
Abstract: A rapid, low cost sensor for Covid-19 was developed using a perfluorodecanthiol layer and ACE2.
Publisher: American Chemical Society (ACS)
Date: 22-10-2020
Publisher: American Chemical Society (ACS)
Date: 19-01-2022
Publisher: Elsevier BV
Date: 09-2018
Location: United States of America
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Perrine Lasserre.