ORCID Profile
0000-0003-0803-593X
Current Organisations
Research Institute for Nature and Forest
,
University of Toronto
,
Qscan
,
Lumus Imaging
,
Gold Coast University Hospital
,
Everlight Radiology
,
Royal Australian and New Zealand College of Radiologists
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Publications
Multiple basal ganglia lesions in an immunocompetent patient.
Publisher: Elsevier BV
Date: 12-2011
DOI: 10.1016/J.JOCN.2011.03.031
Abstract: An osteoporotic fracture (OF) in the second to fifth lumbar vertebrae with spinal stenosis may be an indication for surgical treatment, but carries the risks of instability or instrumentation failure. Modified surgical procedures have been developed to manage patients with challenging OF. We retrospectively studied 12 patients (three male, nine female mean age±standard deviation=73.5±7.2 years) who underwent minimally invasive decompression and posterior column reinforcement with polymethylmethacrylate. During a mean follow-up period of 24.8±3.1 months, pain severity and functional impairment were both significantly reduced, as measured by the visual analog scale and the Oswestry disability index. Nine patients (75%) experienced a satisfactory outcome while the other three (25%) were unchanged. Plain radiographs showed stable spinal alignment and immobilization of flexion-extension within the PMMA construct. Five complications were managed successfully, including one by revision surgery. These procedures are a feasible surgical option in the elderly population studied.
Smoking habits of radiotherapy patients: Did the diagnosis of cancer make an impact and is there an opportunity to intervene?
Publisher: Wiley
Date: 10-2011
DOI: 10.1111/J.1754-9485.2011.02295.X
Abstract: To investigate the impact of a cancer diagnosis on smoking habits in patients receiving radiotherapy and assess the opportunity to intervene. One hundred consecutive patients were interviewed. They included patients newly diagnosed with cancer of any type and receiving radiotherapy. Detailed information was collected including smoking habits before and after the diagnosis, the timing of and reasons for any changes. We also asked about patients' view of the role of the radiation oncologist in smoking cessation and the opportunities for intervention. Analysis of results involved simple descriptive statistics. Although there were only 14 current smokers, only two had decided to quit. Five smokers decreased smoking, six did not change and one increased smoking. One non-smoker (1/34) took up smoking. Nearly all changes occurred within the first 30 days of diagnosis. Most (79%, 11/14) smokers believed that the treating radiation oncologist should discuss smoking cessation with their patients and that the ideal timing is at either the first consultation or when decisions about treatment have been finalised. The diagnosis of cancer can motivate patients to reduce smoking, but few quit altogether and a smaller number increase or even take up smoking. These changes occur early after receiving a diagnosis of cancer. Patients with a smoking history believed that the treating radiation oncologist should discuss smoking cessation with their patients and that the ideal timing is at the first consultation. The periodic nature of treatments and consultations at radiation oncology centres suggest there is the potential for an effective smoking cessation programme.
The Forgotten Art of Plain Radiography in the Evaluation of Metabolic Bone Disease
Publisher: Scientific Scholar
Date: 29-06-2020
Abstract: Although the metabolic bone diseases are fairly commonly encountered in routine practice in India, unfortunately, the clinical presentation is quite non-specific and often remains unrecognized for years, leading to increased morbidity. In this era of advanced imaging technologies, magnetic resonance imaging (MRI) is increasingly being requested by clinicians as an initial investigation for the non-specific presentation of metabolic bone conditions, including back pain, generalized weakness, and arthralgias, and is usually largely non-contributory. Thus, the importance of plain radiographs is neglected. Although basic radiographs are frequently available at the time of MRI, it is often ignored by both the radiologists and clinicians who can lead to misdiagnosis or missed diagnosis. A variety of radiographic findings is encountered in metabolic bone diseases, though often subtle, is unceasingly diagnostic, and recognition of these findings leads to early diagnosis and treatment, resulting in improved patient outcomes. Therefore, the objective of our paper is to present a systematic approach to the interpretation of plain radiographs of the pelvis, spine, and chest that can facilitate identifying subtle imaging findings supported by complementary other region plain radiographs and laboratory data for the evaluation of metabolic bone diseases.
Susceptibility weighted imaging for qualitative grading of persistent arteriovenous shunting in deep-seated arteriovenous malformations after stereotactic radiation surgery
Publisher: SAGE Publications
Date: 21-11-2022
DOI: 10.1177/19714009221140536
Abstract: To investigate Susceptibility Weighted Imaging (SWI) signal changes in the draining vein of deep-seated arterio-venous malformations (AVMs) following stereotactic radiosurgery (SRS). This is a retrospective study of 32 patients with deep-seated AVMs who were treated with SRS. Pre-SRS treatment and post-SRS treatment MRI were performed at 6, 12, and 24-month intervals. Deep-seated AVMs were classified based on their anatomical location and venous drainage pattern. AVM nidal volume (cm 3 ) was estimated using the ABC/2 method. AV shunting of the AVM draining veins were graded according to its SWI signal intensity: hyperintense (grade III), mixed signal intensity (grade II), hypointense (grade I) and absent (grade 0). Conventional time-of-flight (TOF)-MRA and contrast enhanced (CE)-MRA sequences were performed to document the patency of the vein. Pre-SRS treatment AVM draining veins were either grade III 18/32 (56%) or grade II 14/32 (44%). Using mixed effects analysis, we demonstrate that each month following the SRS treatment nidal volumes decreased at the rate of 0.51 cm 3 er month (CI −0.61 to (−0.40)) p =.00. Following the treatment, there was a clinically significant relationship between the signal and nidal volume: signal 0 corresponded with average nidal volume of 1.81 cm 3 (CI 1.40–2.21), signal 1 with nidal volume of 2.06 cm 3 (CI 1.69–2.44), signal 2 with nidal volume 2.73 cm 3 (CI 2.35–3.11) and signal 3 with nidal volume 3.13 cm 3 (CI 2.70–3.56) p = .00. Post-SRS AVM draining veins shows a stepwise regression of the SWI signal grades which can be reliably used as a surrogate to monitor the reduction of AV shunting.
Presumptive diagnosis of multinodular vacuolating tumor: “more than meets the eye!”
Publisher: Springer Science and Business Media LLC
Date: 08-09-2017
Multinodular and Vacuolating Neuronal Tumor of the Cerebrum: A New “Leave Me Alone” Lesion with a Characteristic Imaging Pattern
Publisher: American Society of Neuroradiology (ASNR)
Date: 13-07-2017
DOI: 10.3174/AJNR.A5281
Möbius Syndrome: Comprehensive Assessment of Facial Palsy and Oculomotor Deficits With Magnetic Resonance Imaging
Publisher: Elsevier BV
Date: 11-2015
Distal aortic perfusion during thoracoabdominal aneurysm repair for prevention of paraplegia.
Publisher: Wiley
Date: 14-03-2012
Neuromelioidosis: Craniospinal MRI Findings in Burkholderia pseudomallei Infection
Publisher: Wiley
Date: 10-08-2015
DOI: 10.1111/JON.12282
Abstract: To investigate magnetic resonance imaging (MRI) findings of central nervous system (CNS) infection with Burkholderia pseudomallei. Retrospective analysis of 10 patients (5 male and 5 female, age range from 13 to 69 years) with CNS melioidosis confirmed on culture of blood, sputum, cerebrospinal fluid, brain biopsy, and postmortem brain tissue. Clinical data were collected and MRI brain and/or spine were independently reviewed. Seven patients with brain parenchymal or intramedullary spinal cord lesions demonstrated rim-enhancing microabscesses with propensity for white matter tracts including the corticospinal tracts, corpus callosum, and cerebellar peduncles. Three of these 7 patients also showed thickening and enhancement of the trigeminal nerves with contiguous spread to brain stem trigeminal nuclei. Three patients had isolated extraaxial disease with findings including meningeal enhancement, extradural abscess, skull osteomyelitis, and scalp abscess. Spread of microabscesses along white matter tracts and frequent trigeminal nerve involvement are unique imaging characteristics of CNS melioidosis. These findings may provide insight into potential mechanisms for B. pseuodomallei entry into the CNS through direct axonal transport in cranial nerves bypassing the blood brain barrier. Prompt recognition of the neuroimaging features of this potentially fatal infection may allow for early microbiological culture and treatment.
Embolisation for pulmonary arteriovenous malformation.
Publisher: Wiley
Date: 29-01-2015
The Current State of Susceptibility-Weighted Imaging and Quantitative Susceptibility Mapping in Head Trauma
Publisher: Elsevier BV
Date: 05-2023
Embolisation for pulmonary arteriovenous malformation.
Publisher: John Wiley & Sons, Ltd
Date: 15-08-2012
Embolisation therapy for pulmonary arteriovenous malformations.
Publisher: John Wiley & Sons, Ltd
Date: 12-05-2010
The T1 shine through effect on susceptibility weighted imaging: an under recognized phenomenon
Publisher: Springer Science and Business Media LLC
Date: 13-01-2018
Dual-Layer Spectral CT Imaging of Upper Aerodigestive Tract Cancer: Analysis of Spectral Imaging Parameters and Impact on Tumor Staging
Publisher: American Society of Neuroradiology (ASNR)
Date: 29-07-2021
DOI: 10.3174/AJNR.A7239
“Pseudo” T1-weighted appearance of the brain on FLAIR: unmasking the extent of gray matter involvement on susceptibility-weighted imaging in chronic toluene abuse
Publisher: Springer Science and Business Media LLC
Date: 07-11-2018
High Resolution MRI of Vestibulocochlear Nerve Involvement by a Posterior Fossa Ganglioglioma: Case Report and Review of Literature
Publisher: Springer Science and Business Media LLC
Date: 06-2018
Developmental anomalies of the lateral portion of the cervical neural arch: Multimodal imaging and clinical implications
Publisher: SAGE Publications
Date: 13-05-2020
Abstract: This study aimed to describe the imaging spectrum of developmental anomalies of the lateral portion of the cervical neural arch. This was a five-year retrospective review of consecutive computed tomography (CT) scans of the cervical spine for structural anomalies of the cervical vertebral pedicle and facets. CT, radiographs and, when available, magnetic resonance imaging studies were independently reviewed. Anomalies were grouped into the following three categories: the absence of a pedicle, clefts in the vertebral arch or isolated dysmorphism of the facet. Clinical data on demographics and neurological outcomes were documented. Among 9134 consecutive patients undergoing a CT scan of the cervical spine, 18 (0.2%) patients were found to have developmental anomalies of the pedicle and facets. Findings included 7/18 (39%) with congenital absence of a pedicle, 8/18 (44%) with clefts in the vertebral arch and 3/18 (17%) with isolated dysmorphism of the articular facets. No acute neurological deficits or spinal cord injuries were reported. Associated chronic symptoms included neck pain 10/18 (56%), radiculopathy 7/18 (39%) and myelopathy 1/18 (6%). Developmental anomalies of the pedicle and facet may mimic traumatic spinal pathologies. Recognising a erse spectrum of imaging findings is vital to prevent misdiagnosis and unnecessary intervention.
Magnetic Resonance Imaging Criteria for Post-Concussion Syndrome: A Study of 127 Post-Concussion Syndrome Patients
Publisher: Mary Ann Liebert Inc
Date: 15-05-2020
Abstract: The purpose of this study was to assess the frequency of structural lesions on conventional magnetic resonance imaging (MRI) of the brain in a large prospective cohort of post-concussion syndrome (PCS) patients. Conventional 3T MRI was used to evaluate 127 prospectively enrolled PCS patients and 29 controls for non-specific white matter hyperintensities (WMH) and traumatic structural lesions, including encephalomalacia, atrophy, microhemorrhage, subarachnoid hemorrhage, and cortical siderosis. All PCS patients had a clinical diagnosis of one or more concussions based on the Concussion in Sport Group (CISG) consensus statements. Patients with recognized intracranial hemorrhage on prior head computed tomography (CT) and MRI were excluded. The differences between the PCS and control groups were analyzed. Four patients in the PCS group (3.1%) had positive findings, which included microhemorrhages in two patients and encephalomalacia in another two patients. None of these lesions was present in the control group, but there was no statistical difference between the two groups (
Unexpected Neuroimaging Findings in an Adolescent With First Seizure Presentation.
Publisher: Elsevier BV
Date: 06-2019
Molecular-Based Diversity Studies and Field Surveys Are Not Mutually Exclusive: On the Importance of Integrated Methodologies in Mycological Research
Publisher: Frontiers Media SA
Date: 25-03-2022
DOI: 10.3389/FFUNB.2022.860777
Abstract: Understanding and describing the ersity of living organisms is a great challenge. Fungi have for a long time been, and unfortunately still are, underestimated when it comes to taxonomic research. The foundations were laid by the first mycologists through field observations. These important fundamental works have been and remain vital reference works. Nevertheless, a non-negligible part of the studied funga escaped their attention. Thanks to modern developments in molecular techniques, the study of fungal ersity has been revolutionized in terms of tools and knowledge. Despite a number of disadvantages inherent to these techniques, traditional field-based inventory work has been increasingly superseded and neglected. This perspective aims to demonstrate the central importance of field-based research in fungal ersity studies, and encourages researchers not to be blinded by the sole use of molecular methods.
Pontine Tegmental Cap Dysplasia: MR Evaluation of Vestibulocochlear Neuropathy
Publisher: Wiley
Date: 17-02-2015
DOI: 10.1111/JON.12209
Abstract: Pontine tegmental cap dysplasia (PTCD) is recently recognized as a rare congenital brain stem malformation with typical neuroimaging hallmarks of ventral pontine hypoplasia and vaulted pontine tegmentum projecting into the fourth ventricle. PTCD patients also demonstrate variable cranial neuropathy with predilection for involvement of the vestibulocochlear and facial nerves. We present a case of PTCD diagnosed on MRI in the neonatal period. During early infancy, the patient displayed features of multiple cranial neuropathies and bilateral hearing loss. At the age of 2, the patient underwent further MRI assessment with dedicated high resolution T2 SPACE sequence to delineate the cranial nerve deficiencies.
Iodine-stained fragmented thromboembolism
Publisher: SAGE Publications
Date: 11-09-2019
Abstract: Iodine-stained fragmented thromboembolism (ISFT) is a rare phenomenon encountered in the immediate aftermath of mechanical thrombectomy or rarely as a complication of post–carotid stenting. The aim was to describe the imaging appearance and discuss its pathophysiology. This is a retrospective review of patients who underwent mechanical thrombectomy for acute stroke at a single institution over the period of one year. All patients underwent the standard acute stroke imaging protocol (CT head, CT angiogram (CTA) and CT brain perfusion) and when clinically appropriate followed by catheter angiogram and mechanical thrombectomy. ISFT was defined as an arterial luminal filling defect with Hounsfield density equal to or greater than iodine seen on the biplanar CT or conventional CT. The presence and location of ISFT were documented. Standard CT angiogram (CTA) or magnetic resonance angiogram (MRA) was performed 24–48 hours after the neurointerventional procedure to assess for recanalization, volume of infarction and the fate of the ISFT. ISFTs were identified in eight (five males and three females, age range 18–80 years) out of 49 patients in the following locations: distal M1 ( n = 1), M2 ( n = 4), M3 ( n = 1), A1 ( n = 1), distal A2 ( n = 1). ISFT and vessel recanalization occurred in five patients on follow-up. ISFT and vessel occlusion persisted in two patients. ISFT is likely the result of mechanical disruption of a thromboembolus, and porosity of the thromboembolus fragment may transiently retain iodinated contrast. Recognition of this entity may be important to aid detection of residual thromboembolism and avoid misinterpretation as calcified thromboembolism.
Susceptibility and Volume Measures of the Mammillary Bodies Between Mild Cognitively Impaired Patients and Healthy Controls
Publisher: Frontiers Media SA
Date: 15-09-2020
High resolution magnetic resonance imaging for exposing facial nerve zonal vulnerability to microbleeds: A rare cause of facial palsy.
Publisher: SAGE Publications
Date: 20-06-2017
Abstract: We report a case of hypertensive microbleeds strategically located at the attached segment (AS) and root entry zone (REZ) at the left facial nerve causing facial paralysis. A 60-year-old woman presented with sudden onset left facial paralysis. Medical history was significant for poorly controlled hypertension secondary to bilateral adrenal hyperplasia (primary hyperaldosteronism). The patient was initially treated for presumptive Bell’s palsy. Subsequent magnetic resonance imaging of the brain and internal auditory canal showed two microbleeds at the left cerebellopontine angle. Dedicated coronal T1 magnetization prepared rapid acquisition gradient echo and T2 s ling perfection with application optimized contrasts using different flip angle evolution sequences revealed two acute microbleeds located at the attached AS and REZ of the left facial nerve. The patient experienced only partial recovery from House–Brackmann grade IV facial paralysis at presentation to a House–Brackmann grade III facial paralysis at 1 year of follow up. To the best of the authors’ knowledge, this is the first reported case of facial paralysis caused by microbleeds directly affecting the vulnerable AS and REZ facial nerve segments. We discuss the zonal microanatomy of the facial nerve and the crucial role of high resolution MRI for diagnosis.
Non-traumatic cerebrospinal fluid rhinorrhea caused by ethmoid sinus osteoma.
Publisher: Elsevier BV
Date: 09-2010
DOI: 10.1016/J.JOCN.2009.11.028
Abstract: Cerebrospinal fluid (CSF) rhinorrhea is a rare complication of ethmoid sinus osteoma, considering its benign and indolent nature. We present a 36-year-old female patient with symptomatic CSF rhinorrhea as a primary presentation of ethmoid sinus osteoma. We have highlighted the imaging features and emphasised the importance of imaging in the diagnosis of spontaneous CSF leak.
Venous cutdown versus the Seldinger technique for placement of totally implantable venous access ports
Publisher: Wiley
Date: 21-08-2016
High-Resolution MRI Vessel Wall Imaging in Acute Aneurysmal Subarachnoid Hemorrhage
Publisher: Springer Science and Business Media LLC
Date: 30-10-2019
DOI: 10.1007/S00062-019-00843-8
Abstract: The spatiotemporal pattern of vessel wall changes was investigated on two time point magnetic resonance images (MRI) in patients with aneurysmal subarachnoid hemorrhages (aSAH) and its association with clinicoradiologic severity score and delayed cerebral ischemia (DCI) was analyzed. A total of 32 prospectively enrolled patients with aSAH (mean age 56.94 years 9 male and 23 female) underwent vessel wall imaging (VWI) MRI. Of the patients 20 completed two time point MRIs early and late during the admission, 10 patients only had early MRI and 2 patients only had late MRI. Timing of early MRI had a mean of 2.5 days (range 1-6 days) and late MRI had a mean of 10.5 days (range 7-16 days) from time of admission. Spatiotemporal pattern of vessel wall enhancement (VWE), vasospasm, diffusion-weighted imaging (DWI) lesion burden (grade 0-III) and infarcts were analyzed against the clinicoradiologic severity score (high-risk: vasograde red and yellow, low-risk: vasograde green) and DCI. On the early MRI, mild VWE alone was significantly more frequent in the high-risk group (36.7% versus 20.0% P = 0.024). On the late MRI, vasospasm was significantly more frequent in the high-risk group (27.2% versus 4.5% P = 0.022). Vasospasm infrequently showed mild VWE (6.67% on early MRI and 9.09% on late MRI). Both mild VWE alone on early MRI and on late MRI were significantly associated with development of DCI during the admission (P = 0.034 and P = 0.035, respectively). Mild VWE on early MRI and vasospasm on late MRI were significantly more prevalent in high-risk and DCI patients suggesting VWI might enable imaging of early neuroinflammatory changes which are part of the pathomechanism of vasospasm and DCI.
Angioplasty versus stenting for infrapopliteal arterial lesions in chronic limb-threatening ischaemia.
Publisher: Wiley
Date: 08-12-2018
Yellow droopy eyes: A case of obstructive jaundice from Burkitt's lymphoma with involvement of bilateral cavernous sinus
Publisher: Elsevier BV
Date: 03-2023
Scedosporium apiospermum endophthalmitis: diffusion-weighted imaging in detecting subchoroidal abscess.
Publisher: Informa UK Limited
Date: 11-2012
DOI: 10.2147/OPTH.S25697
Acquired Metabolic Diseases
Publisher: Springer International Publishing
Date: 2019
More on Exploiting the T1 Shinethrough and T2* Effects Using Multiecho Susceptibility-Weighted Imaging
Publisher: American Society of Neuroradiology (ASNR)
Date: 24-06-2021
DOI: 10.3174/AJNR.A7175
Rosette-forming glioneuronal tumour: imaging features, histopathological correlation and a comprehensive review of literature.
Publisher: Informa UK Limited
Date: 18-04-2012
DOI: 10.3109/02688697.2012.655808
Abstract: Rosette-forming glioneuronal tumour (RGNT) is a rare and novel brain tumour. We present a case of rosette forming glioneuronal tumour of the fourth ventricle and highlight the imaging and histological features of this tumour entity. We also performed a comprehensive review of the imaging features, treatments and outcomes of all past cases and make recommendations on diagnosis and management. We conducted a PUBMED search using the words 'rosette forming glioneuronal tumour', and identified 48 cases of rosette forming glioneuronal tumour. We reviewed the location, imaging features of this rare tumour entity as well as the treatment and follow-up. We also present a case of a 42-year-old man with an incidental finding of a solid-cystic midline mass in the posterior fossa at the level of fourth ventricle with morphological features and immunohistochemical characteristic of a RGNT (WHO Grade I). RGNT is commonly found in association with the fourth ventricle often with local extension however, it is known to occur at sites outside of its usual location. RGNT can demonstrate solid, cystic or mixed features on MRI and frequently shows focal contrast enhancement. It is often associated with an element of hydrocephalus. Gross or subtotal tumour resection was the most common treatment of choice. Due to the intimate relationship of these tumours to key neural structures in the cerebellum, variable degrees of postoperative neurological deficits were reported in half of the patients. Among the reported cases, no evidence of recurrence following gross or subtotal resection of tumour was seen in the majority of patients. However, owing to lack of lengthy follow-up, we recommend routine imaging follow-up. Knowledge of this tumour is of importance as they are relatively slow growing and exhibit benign histological characteristics, thus depending on its location maybe amenable to gross total resection.
HARMless: Transient Cortical and Sulcal Hyperintensity on Gadolinium-Enhanced FLAIR after Elective Endovascular Coiling of Intracranial Aneurysms
Publisher: American Society of Neuroradiology (ASNR)
Date: 22-02-2018
DOI: 10.3174/AJNR.A5561
Editorial for “High‐Resolution Vessel Wall MR Imaging in Diagnosis and Length Measurement of Cerebral Arterial Thrombosis: A Feasibility Study”
Publisher: Wiley
Date: 18-03-2022
DOI: 10.1002/JMRI.28171
High resolution CT study of the chorda tympani nerve and normal anatomical variation
Publisher: Springer Science and Business Media LLC
Date: 08-04-2015
DOI: 10.1007/S11604-015-0417-2
Abstract: The aim of this study was to define the normal anatomical variation of the course of the CTN through the mastoid temporal bone on high resolution CT (HRCT). Retrospective review of 27 consecutive normal HRCT bilateral temporal bones (n = 54, 14 males and 13 females, mean age 41 years) reconstructed at 0.4-mm slice thickness specifically measuring (1) origin of CTN from the posterior genu of the facial nerve (CNVII) and (2) the lateral-most position of the CTN from the mastoid segment of CNVII. The mean distance of the CTN origin from the mastoid segment of CNVII was 11.5 mm (standard deviation, SD = 3.2, 95% CI 10.7-12.3) with no statistically significant difference between the left and right side observed (p = 0.08). The most lateral distance of the CTN from CNVII was a mean of 1.3 mm (SD = 0.6, 95% CI 1.2-1.7), range 0-2.5 mm and again no statistical significance between contralateral sides was observed (p = 0.11). These measurements demonstrated an excellent level of agreement between observers as assessed by intraclass correlation calculation. Reproducible measurements demonstrate variability of the CTN in both its origin from the mastoid segment of CNVII and its lateral-most course. Precise description of the course of the CTN with HRCT may be useful for planning of otologic surgery and limiting inadvertent nerve injury.
Reply:
Publisher: American Society of Neuroradiology (ASNR)
Date: 19-10-2017
DOI: 10.3174/AJNR.A5447
Quantitative Susceptibility Mapping for Characterization of Intraplaque Hemorrhage and Calcification in Carotid Atherosclerotic Disease
Publisher: Wiley
Date: 10-02-2020
DOI: 10.1002/JMRI.27064
Spontaneous aorto-left renal vein fistula: a rare complication of abdominal aortic aneurysm
Publisher: Wiley
Date: 26-11-2013
DOI: 10.1111/ANS.12477
Quantifying Tissue Properties of the Optic Radiations Using Strategically Acquired Gradient Echo Imaging and Enhancing the Contrast Using Diamagnetic Susceptibility Weighted Imaging
Publisher: American Society of Neuroradiology (ASNR)
Date: 24-12-2020
DOI: 10.3174/AJNR.A6897
High-Resolution Diffusion Tensor Imaging and Tractography in Joubert Syndrome: Beyond Molar Tooth Sign
Publisher: Elsevier BV
Date: 07-2015
DOI: 10.1016/J.PEDIATRNEUROL.2015.02.027
Abstract: We undertook diffusion tensor imaging analysis of brainstem fiber tracts in two Joubert syndrome patients. Two Joubert syndrome patients underwent magnetic resonance imaging brain examination with diffusion tensor imaging. Imaging findings were compared with five age- and sex-matched control subjects with approval from the institutional ethic committee. The medical history and clinical examination findings in both patients were documented. Diffusion tensor imaging analysis of the first patient demonstrated absence of the dorsal pontocerebellar tract and thinning of the middle cerebral peduncle. Diffusion tensor imaging analysis of the second child revealed thinning of the both the dorsal pontocerebellar and ventral pontocerebellar tract. Both patients exhibited thickened and horizontally oriented superior cerebellar peduncles. The superior cerebellar peduncles also failed to decussate in the mesencephalon. Pontocerebellar tract abnormalities in Joubert syndrome patients have not been previously recognized. The difference in the pontocerebellar tract between the two Joubert syndrome patients suggests a spectrum of severity of pontine axonal migration abnormality.
Serial magnetic resonance imaging findings of intracerebral spread of listeria utilising subcortical U-fibres and the extreme capsule.
Publisher: SAGE Publications
Date: 26-09-2016
Abstract: We present a case of Listeria monocytogenes cerebral abscess with axonal spread via the subcortical U-fibres and extreme capsule on magnetic resonance imaging, with follow-up studies demonstrating serial reduction in oedema and enhancement pattern of the white-matter fibre tracts following antimicrobial treatment. We discuss the microbiological mechanism of bacterial mobility to account for these unique imaging features. Recognition of this distinct pattern of spread of L. monocytogenes cerebral abscess may aid in diagnosis and enable early microbiological culture and treatment.
Tumefactive Primary Central Nervous System Vasculitis: Imaging Findings of a Rare and Underrecognized Neuroinflammatory Disease
Publisher: American Society of Neuroradiology (ASNR)
Date: 03-09-2020
DOI: 10.3174/AJNR.A6736
Susceptibility weighted imaging in acute cerebral ischemia: review of emerging technical concepts and clinical applications
Publisher: SAGE Publications
Date: 20-02-2017
Abstract: Susceptibility weighted imaging (SWI) is an essential magnetic resonance imaging sequence in the assessment of acute ischemic stroke. In this article, we discuss the physics principals and clinical application of conventional SWI and multi-echo SWI sequences. We review the research evidence and practical approach of SWI in acute ischemic stroke by focusing on the detection and characterization of thromboembolism in the cerebral circulation. In addition, we discuss the role of SWI in the assessment of neuroparenchyma by depiction of asymmetric hypointense cortical veins in the ischemic territory (surrogate tissue perfusion), detection of existing microbleeds before stroke treatment and monitoring for hemorrhagic transformation post-treatment. In conclusion, the SWI sequence complements other parameters in the stroke magnetic resonance imaging protocol and understanding of the research evidence is vital for practising stroke neurologists and neuroradiologists.
Stroke-like migraine attacks after radiation therapy (SMART) Syndrome causing permanent neurological deficit
Publisher: Medknow
Date: 2015
Ipilimumab-induced hypophysitis and ileocolitis: Serial pituitary MRI findings.
Publisher: Medknow
Date: 2017
Symptomatic Developmental Venous Anomaly: State-of-the-Art Review on Genetics, Pathophysiology, and Imaging Approach to Diagnosis
Publisher: American Society of Neuroradiology (ASNR)
Date: 30-03-2023
DOI: 10.3174/AJNR.A7829
Related Organisations
Royal Australian And New Zealand College Of Radiologists
Location: Australia
Related Funding Activities
No related grants have been discovered for Charlie Chia-Tsong Hsu.