ORCID Profile
0000-0001-7999-5079
Current Organisations
Yale University
,
Chittagong University of Engineering and Technology
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Publisher: Cold Spring Harbor Laboratory
Date: 13-03-2022
DOI: 10.1101/2022.03.10.22272203
Abstract: Acute brain injury remains common after extracorporeal cardiopulmonary resuscitation. Using a large international multicenter cohort, we investigated the impact of peri-cannulation arterial oxygen (PaO 2 ) and carbon dioxide (PaCO 2 ) on ABI occurrence. Retrospective cohort study. Data in the Extracorporeal Life Support Organization Registry from 2009 to 2020. Adult patients (≥18 years old) who underwent extracorporeal cardiopulmonary resuscitation. None. Of 3,125 patients with extracorporeal cardiopulmonary resuscitation (median age=58, 69% male), 488 (16%) experienced at least one form of acute brain injury, which included ischemic stroke, intracranial hemorrhage, seizures, and brain death. 217 (7%) experienced ischemic stroke and 88 (3%) experienced intracranial hemorrhage. The registry collects two blood gas data pre- (6 hours before) and on- (24 hours after) extracorporeal membrane oxygenation (ECMO) cannulation. Blood gas parameters were classified as: hypoxia ( mmHg), normoxia (60-119mmHg), and mild (120-199mmHg), moderate (200-299mmHg), and severe hyperoxia (≥300mmHg) hypocarbia ( mmHg), normocarbia (35-44mmHg), mild (45-54mmHg) and severe hypercarbia (≥55mmHg). In multivariable logistic regression analysis, pre-ECMO hypoxia (aOR=1.46, 95%CI: 1.03-2.08, p=0.04) and on-ECMO severe hyperoxia (aOR=1.55, 95%CI: 1.02-2.36, p=0.04) were associated with composite ABI. Also, on-ECMO severe hyperoxia was associated with intracranial hemorrhage (aOR=1.88, 95%CI: 1.02-3.47, p=0.04) and in-hospital mortality (aOR=3.51, 95%CI: 1.98-6.22, p .001). Pre- and on-ECMO PaCO 2 levels were not significantly associated with composite ABI or mortality, though mild hypercarbia pre- and on-ECMO were protective of ischemic stroke and intracranial hemorrhage, respectively. Early severe hyperoxia (≥300mmHg) on ECMO was a significant risk factor for acute brain injury and mortality for patients undergoing extracorporeal cardiopulmonary resuscitation. Careful consideration should be given in early oxygen delivery in ECPR patients who are at risk of reperfusion injury.
Publisher: AIP Publishing
Date: 2023
DOI: 10.1063/5.0125200
Abstract: In this study, the influence of hydrothermal reaction temperatures on V2O5synthesized via a green facile mild hydrothermal method at six different reaction temperatures ranging from 100 to 200 °C, at steps of 20 °C and the physical properties the synthesized s les have been investigated. The x-ray diffraction pattern confirms the stable orthorhombic crystal structure of the synthesized s les at all reaction temperatures. The scanning electron microscopy and transmission electron microscopy images demonstrate the particle-like morphology, and these characterizations affirmed that the particles’ size became larger with the increase in the reaction temperatures. To study the functional groups, Fourier-transform infrared investigation has been employed. The bandgap of the synthesized s les has been estimated using UV-vis diffuse reflectance spectra and was found to vary from 2.08 to 2.15 eV, which implies their suitability for absorbing a significant amount of visible light. The photocatalysis of methylene blue with synthesized s les has been carried out to investigate the photocatalytic efficiency. Pure V2O5 synthesized at a lower reaction temperature (100 °C) possesses a lower bandgap and, accordingly, higher photocatalytic efficiency.
Publisher: Elsevier BV
Date: 09-2019
Publisher: Elsevier BV
Date: 12-2017
Publisher: Wiley
Date: 25-08-2017
Abstract: For the first time, we have reported in this study an ab initio investigation on elastic properties, Debye temperature, Mulliken population, Vickers hardness, and charge density of the two recently synthesized superconducting ScRhP and ScIrP pnictides. The optimized cell parameters show fair agreement with the experimental results. The mechanical stability of both ternary phosphides is confirmed via the calculated elastic constants. Both compounds are ductile in nature and damage tolerant. ScIrP is expected to be elastically more anisotropic than ScRhP. The estimated value of Debye temperature predicts that ScRhP is thermally more conductive than ScIrP and the phonon frequency in ScRhP is higher than that in ScIrP. Both pnictides are soft and easily machinable due to their low Vickers hardness. Moreover, the hardness of ScRhP is lower due to the presence of antibonding Rh–Rh in ScRhP. The metallic conductivity of ScRhP reduces significantly when Rh is replaced with Ir. The main contribution to the total density of states (TDOS) at Fermi‐level ( E F ) comes from d‐electrons of Sc and Rh/Ir in both pnictides. These two ternary compounds are characterized mainly by metallic and covalent bonding with little ionic contribution. The calculated superconducting transition temperatures fairly coincide with the reported measured values.
Publisher: Elsevier BV
Date: 04-2019
Publisher: Elsevier BV
Date: 04-2023
DOI: 10.1016/J.HEALUN.2022.10.019
Abstract: Acute brain injury (ABI) remains common after extracorporeal cardiopulmonary resuscitation (ECPR). Using a large international multicenter cohort, we investigated the impact of peri-cannulation arterial oxygen (PaO We retrospectively analyzed adult (≥18 years old) ECPR patients in the Extracorporeal Life Support Organization registry from 1/2009 through 12/2020. Composite ABI included ischemic stroke, intracranial hemorrhage (ICH), seizures, and brain death. The registry collects 2 blood gas data pre- (6 hours) and post- (24 hours) cannulation. Blood gas parameters were classified as: hypoxia (<60mm Hg), normoxia (60-119mm Hg), and mild (120-199mm Hg), moderate (200-299mm Hg), and severe hyperoxia (≥300mm Hg) hypocarbia (<35mm Hg), normocarbia (35-44mm Hg), mild (45-54mm Hg) and severe hypercarbia (≥55mm Hg). Missing values were handled using multiple imputation. Multivariable logistic regression analysis was used to assess the relationship of PaO Of 3,125 patients with ECPR intervention (median age=58, 69% male), 488 (16%) experienced ABI (7% ischemic stroke 3% ICH). In multivariable analysis, on-ECMO moderate (aOR=1.42, 95%CI: 1.02-1.97) and severe hyperoxia (aOR=1.59, 95%CI: 1.20-2.10) were associated with composite ABI. Additionally, severe hyperoxia was associated with ischemic stroke (aOR=1.63, 95%CI: 1.11-2.40), ICH (aOR=1.92, 95%CI: 1.08-3.40), and in-hospital mortality (aOR=1.58, 95%CI: 1.21-2.06). Mild hypercarbia pre-ECMO was protective of composite ABI (aOR=0.61, 95%CI: 0.44-0.84) and ischemic stroke (aOR=0.56, 95%CI: 0.35-0.89). Early severe hyperoxia (≥300mm Hg) on ECMO was a significant risk factor for ABI and mortality. Careful consideration should be given in early oxygen delivery in ECPR patients who are at risk of reperfusion injury.
Location: Singapore
Location: Bangladesh
No related grants have been discovered for Md. Mohi Uddin.