ORCID Profile
0000-0002-5959-1808
Current Organisation
University of Western Australia
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In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Interdisciplinary Engineering | Simulation and Modelling | Engineering Practice | Infrastructure Engineering and Asset Management
Productivity (excl. Public Sector) | Mining Machinery and Equipment | Expanding Knowledge in Engineering |
Publisher: Elsevier BV
Date: 03-2014
Publisher: Informa UK Limited
Date: 20-03-2019
Publisher: AIP
Date: 2012
DOI: 10.1063/1.3703638
Publisher: Revista Brasileira de Biometria
Date: 25-03-2019
Abstract: Devido à relevância do uso de técnicas de revisão sistemática e metanálise na aquisição de informações consistentes e fidedignas nas ersas áreas do conhecimento, este artigo apresenta a versão preliminar 1.0.0 do software Calculadora Metanalítica, desenvolvido nas linguagens R e C#, com interface gráfica amigável, que realiza uma metanálise bayesiana de proporções. O software possibilita que o usuário entre com os pesos dos estudos, caso desejar. Além do gráfico resultante da metanálise, também pode ser salvo um arquivo texto que possibilita a realização de análises complementares. Os passos para instalação e utilização do programa são aqui descritos. Para aplicação do software é apresentado um exemplo de metanálise para a prevalência de sintomas depressivos em idosos brasileiros hospitalizados em unidades de saúde do Brasil. Ao final, são apresentadas algumas considerações da utilização da Calculadora Metanalítica.
Publisher: Wiley
Date: 10-05-2016
Publisher: AIP
Date: 2009
DOI: 10.1063/1.3275613
Publisher: AIP
Date: 2012
DOI: 10.1063/1.4759611
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2018
Publisher: Elsevier BV
Date: 11-2018
DOI: 10.1016/J.CHEMOSPHERE.2018.08.019
Abstract: Aquatic ecosystems are composed by a myriad of dissolved organic materials that can be assimilated by microalgae, while they can perform photosynthesis, this is refereed as mixotrophy. However, ecotoxicological tests usually consider only the photoautotrophic metabolism. This research investigated the ecotoxicological differences between photoautotrophy and mixotrophy in Chlorella sorokiniana exposed to cadmium (Cd). Chlorophyll a, photosynthetic efficiency (Fv/Fm), cell viability, biochemical composition and pH were used to monitor possible toxic effects at 72 h cultures. Glucose (1 g.L
Publisher: Springer International Publishing
Date: 2018
Publisher: MDPI AG
Date: 23-04-2014
Publisher: Hindawi Limited
Date: 2012
DOI: 10.1155/2012/457054
Abstract: This study aimed to investigate cytological abnormalities indicative of chromosome damage (micronuclei) and apoptosis (karyorrhexis, pyknosis, and condensed chromatin) in exfoliated cells from the buccal mucosa of patients with oral cancer and control subjects. The s le included twenty in iduals with oral cancer and forty in iduals with normal buccal mucosa. Material was collected from the cheek epithelium in areas with lesions and areas without abnormalities. A minimum of one thousand cells was analyzed. Micronuclei were found significantly more frequently in cells collected from lesions than in cells from normal areas, independent of the presence/absence of cancer ( P 0.0001 ). They were also significantly more frequent in smokers and in mouthwash users ( P 0.0001 ). Apoptosis occurred significantly less frequently in in iduals with oral cancer ( P 0.0001 ). These results show that oral cancer is associated with higher frequency of chromosomal damage and suggest that apoptosis is compromised in the buccal cells of in iduals with this kind of neoplasia.
Publisher: Begell House
Date: 2012
Publisher: Sociedade Brasileira de Computação - SBC
Date: 15-10-2019
Abstract: A predição de PIWI-Interacting RNAs (piRNAs) é um tópico de interesse relacionado a pequenos RNAs não-codificantes, fornecendo pistas para a compreensão do mecanismo de geração de gametas. Várias abordagens de aprendizado de máquina foram propostas para a predição de piRNAs, mas ainda busca-se melhorias. Devido à grande variedade de RNAs não-codificantes, a escolha de quais deles serão utilizados como exemplos negativos pode ser uma tarefa trabalhosa. Em tais cenários, classificadores de uma classe podem ser uma opção. Assim, este trabalho investiga o poder de predição de classificadores de uma única classe em comparação aos classificadores binários para predição de piRNAs.
Publisher: Springer New York
Date: 2013
Publisher: Springer International Publishing
Date: 2018
Publisher: Public Library of Science (PLoS)
Date: 02-08-2018
Publisher: MDPI AG
Date: 07-03-2018
DOI: 10.3390/E20030176
Publisher: Springer International Publishing
Date: 2015
Publisher: AIP
Date: 2008
DOI: 10.1063/1.3039002
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2009
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2013
Publisher: MDPI AG
Date: 20-12-2020
DOI: 10.3390/E22121438
Abstract: With the increase in data processing and storage capacity, a large amount of data is available [...]
Publisher: Informa UK Limited
Date: 09-2016
Publisher: IEEE
Date: 07-2009
Publisher: Wiley
Date: 26-09-2012
Publisher: AIP
Date: 2012
DOI: 10.1063/1.4759589
Publisher: Public Library of Science (PLoS)
Date: 06-05-2016
Publisher: MDPI AG
Date: 04-12-2019
DOI: 10.3390/CELLS8121566
Abstract: Breast cancer stromal compartment, may influence responsiveness to chemotherapy. Our aim was to detect a stromal cell signature (using a direct approach of microdissected stromal cells) associated with response to neoadjuvant chemotherapy (neoCT) in locally advanced breast cancer (LABC). The tumor s les were collected from 44 patients with LABC (29 estrogen receptor (ER) positive and 15 ER negative) before the start of any treatment. Neoadjuvant chemotherapy consisted of doxorubicin and cyclophosphamide, followed by paclitaxel. Response was defined as downstaging to maximum ypT1a-b/ypN0. The stromal cells, mainly composed of fibroblast and immune cells, were microdissected from fresh frozen tumor s les and gene expression profile was determined using Agilent SurePrint G3 Human Gene Expression microarrays. Expression levels were compared using MeV (MultiExperiment Viewer) software, applying SAM (significance analysis of microarrays). To classify s les according to tumor response, the order of median based on confidence statements (MedOr) was used, and to identify gene sets correlated with the phenotype downstaging, gene set enrichment analysis (GSEA). Nine patients presented disease downstaging. Eleven sequences (FDR 17) were differentially expressed, all of which (except H2AFJ) more expressed in responsive tumors, including PTCHD1 and genes involved in abnormal cytotoxic T cell physiology, TOX, LY75, and SH2D1A. The following four pairs of markers could correctly classify all tumor s les according to response: PTCHD1/PDXDC2P, LOC100506731/NEURL4, SH2D1A/ENST00000478672, and TOX/H2AFJ. Gene sets correlated with tumor downstaging (FDR 0.01) were mainly involved in immune response or lymphocyte activation, including CD47, LCK, NCK1, CD24, CD3E, ZAP70, FOXP3, and CD74, among others. In locally advanced breast cancer, stromal cells may present specific features of immune response that may be associated with chemotherapy response.
Publisher: IWA Publishing
Date: 04-03-2016
DOI: 10.2166/WST.2016.111
Abstract: Cylindrospermopsis raciborskii is a potentially toxic cyanobacterium that excretes organic materials which act as ligands for metals. Metal ligands may be characterized for their strength of association, e.g., stability constants, which can be either thermodynamic (K) or conditional (K’). In this research we examined K and K’ for Cu and Cd complexes with three molecular weight fractions (& kDa 30–10 kDa 10–3 kDa) of the cyanobacteria EOM. Complexation capacities of the excreted organic materials (EOM) for metals were determined at several ionic strengths (1.0 × 10−2, 5.0 × 10−2, 1.0 × 10−1, and 5.0 × 10−1 mol L−1) at pH 6.6 ± 0.1, with ligands for which no data for their acidity constants are available these constants are thus conditional for this specific pH. Bayesian statistics showed that with a probability of 95–100% the EOM have two different ligands for Cu but only one for Cd, that ligands for Cu were stronger than for Cd (94–100% probability), and that the smallest EOM fraction had the highest strength of association for Cu (logKCuL 13.5). The lowest affinity was obtained for Cd (logKCdL 8.6) complexed to any molecular weight fraction. The present findings have important ecological implications, since the metal–ligand association is dynamic, and together with a ersity of ligands it can act as an environmental metal buffer. As a result, higher metal loads may be necessary for the detection of toxicity.
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2019
Publisher: Scientific Research Publishing, Inc.
Date: 2020
Publisher: Springer International Publishing
Date: 08-11-2013
Publisher: Universidade de Sao Paulo, Agencia USP de Gestao da Informacao Academica (AGUIA)
Date: 24-05-2011
DOI: 10.4237/GTP.V6I1.118
Publisher: Elsevier BV
Date: 12-2011
Publisher: Scientific Research Publishing, Inc.
Date: 2014
Publisher: MDPI AG
Date: 08-10-2016
DOI: 10.3390/E18100357
Publisher: Springer International Publishing
Date: 2018
Publisher: MDPI AG
Date: 11-09-2018
DOI: 10.3390/E20090694
Abstract: The 37th edition of MaxEnt was held in Brazil, hosting several distinguished researchers and students. The workshop offered four tutorials, nine invited talks, twenty four oral presentations and twenty seven poster presentations. All submissions received their first choice between oral and poster presentations. The event held a celebration to Julio Stern’s 60th anniversary and awarded two prizes to young researchers. As customary, the workshop had one free afternoon, in which participants visited the city’s surroundings and experienced Brazilian food and traditions.
Publisher: Springer International Publishing
Date: 2015
Publisher: Wiley
Date: 11-01-2019
DOI: 10.1002/ETC.4332
Abstract: Copper (Cu) nanomaterials have been increasingly researched and produced for many different consumer products. They have high reactivity and bactericidal properties, making them important in antifouling paints, which are thus directly introduced into aquatic ecosystems. However, studies are scarce on the behavior of Cu nanoparticles (Cu-NPs) in natural aquatic systems and their interactions with primary producers such as microalgae. We investigated the effects of NPs on some physiological responses of the freshwater phytoplankton Chlorella sorokiniana. The cells were exposed to nominal concentrations ranging from 2.50 to 635.00 μg L
Start Date: 02-2019
End Date: 02-2025
Amount: $3,925,357.00
Funder: Australian Research Council
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