ORCID Profile
0000-0002-4502-1441
Current Organisation
Badan Riset dan Inovasi Nasional Republik Indonesia
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Publisher: Springer Science and Business Media LLC
Date: 04-11-2020
DOI: 10.1038/S41564-019-0597-0
Abstract: Staphylococcus aureus small colony variants (SCVs) are frequently associated with chronic infection, yet they lack expression of many virulence determinants associated with the pathogenicity of wild-type strains. We found that both wild-type S. aureus and a ΔhemB SCV prototype potently activate glycolysis in host cells. Glycolysis and the generation of mitochondrial reactive oxygen species were sufficient to induce necroptosis, a caspase-independent mechanism of host cell death that failed to eradicate S. aureus and instead promoted ΔhemB SCV pathogenicity. To support ongoing glycolytic activity, the ΔhemB SCV induced over a 100-fold increase in the expression of fumC, which encodes an enzyme that catalyses the degradatin of fumarate, an inhibitor of glycolysis. Consistent with fumC-dependent depletion of local fumarate, the ΔhemB SCV failed to elicit trained immunity and protection from a secondary infectious challenge in the skin. The reliance of the S. aureus SCV population on glycolysis accounts for much of its role in the pathogenesis of S. aureus skin infection.
Publisher: IOP Publishing
Date: 05-2021
DOI: 10.1088/1755-1315/743/1/012066
Abstract: The cotton development program in Indonesia is prioritized to support the national textile industry. Program on Cotton Intensification for Smallholders (IKR) began in 1978/1979 with cotton planted area 15-22 ha and using introduced cotton varieties. The fiber quality of these introduced varieties was appropriate for the raw materials of the textile industry. However, the introduced varieties were not following the Indonesian agroecosystem, especially their resistance to the main cotton pest, namely cotton planthopper, Amrasca biguttulla Ishida. The purpose of this review is to study the development of Indonesian cotton varieties and their use as raw materials in the textile industry. The development of Indonesian cotton varieties began in 1985 oriented to the varieties with characters on high productivity and resistance to cotton planthopper. In the development of the Indonesian National Cotton (Kanesia) variety, there was an increase in production potential and fiber quality, so that it affected its use in the textile industry. From 1990 to 1998, cotton varieties Kanesia 1 - Kanesia 7 were released with high productivity character orientation, namely 350-902.4 kg fiber/ha and relatively resistant to cotton planthopper with a fiber length of 27.78-31.75 mm (fiber category: medium-long). In 2003 Kanesia 8 and Kanesia 9 were released by improving the character of production and fiber content, id., 650.8-962.2 kg fiber/ha, with fiber lengths of 29.2-30.3 mm (fiber category: medium-long). In 2007 6 new superior varieties were released, namely Kanesia 10 - Kanesia 15 with improved character production potential (586,5-1,178.8 kg fiber/ha), as well as drought-resistant characters for Kanesia 14 and Kanesia 15, fiber length 26,92-29.97 mm (fiber category: medium-long). In 2014, 5 varieties Kanesia 16 - Agri Kanesia 20 were released with improvements to the character of production potential, namely 478.4-1,616.3 kg fiber/ha, and also improvement in fiber quality for the character of strength, elasticity, and smoothness of fiber, with fiber length, 28.7-29.6 mm (medium fiber category). Kanesia 21 - Kanesia 23 were released in 2017 with improvements to the character of production potential, namely 726.1-1,420.3 kg of fiber/ha and improvement in the character of fiber elasticity. Fiber quality is the main character for determining the use of cotton fiber to be processed into yarn (yarn) and the subsequent process to become textile.
Publisher: IOP Publishing
Date: 2020
DOI: 10.1088/1755-1315/418/1/012073
Abstract: There are four color groups of cotton fiber, namely white, brown, green and blue. The most cultivated colored-cottons are brown and green cotton fiber. The program for assembling colored-cotton varieties, especially brown color in Indonesia began in 2006. Crossing activities used three Indonesian National Cotton superior varieties, namely Kanesia 7, Kanesia 8 and Kanesia 9 as female founder and three cotton accessions with brown fiber cotton characters 73814, Multiple Dominant and RLBL as male founder. From crosses followed by selection based on desired character, tests of selected lines and multi-location tests of expected lines, we obtained 3 brown-cotton-fiber varieties with 3 color gradations: Bronesia 1 (light brown), Bronesia 2 (light brown), and Bronesia 3 (dark brown). The potential production of the three varieties are 909 kg, 859 kg, 1,010 kg fiber/ha, respectively. The quality of Bronesian cotton fiber is generally lower compared to the new superior varieties of white fiber cotton (Kanesia 16-Kanesia 23) for fiber length and strength. Cotton fibers of Bronesian varieties are classified as short fibers (23.2-25.7 mm), so that manual and conventional spinning techniques will produce yarn suitable for traditional weaving, especially for woven fabrics with brown based colors.
Publisher: AIP Publishing
Date: 2022
DOI: 10.1063/5.0075716
Location: Indonesia
No related grants have been discovered for Taufiq Hidayat Rahman Side.