ORCID Profile
0000-0001-7653-5392
Current Organisation
James Cook University
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Publisher: Informa UK Limited
Date: 09-09-2020
Publisher: Elsevier BV
Date: 04-2012
DOI: 10.1016/J.PSYCHRES.2011.12.027
Abstract: We contrasted demographic and clinical characteristics in transethnic schizophrenia populations from Australia (n=821), India (n=520) and Sarawak, Malaysia (n=298) and proposed cultural explanations for identified site differences. From these we aimed to identify candidate variables free from significant cultural confounding that are hence suitable for inclusion in genetic analyses. We observed five phenomena: (1) more in iduals were living alone in Australia than India or Sarawak (2) drug use was lower in India than Australia or Sarawak (3) duration of untreated psychosis (DUP) was longer in India than Australia or Sarawak (4) the rate of schizoaffective disorder was lower in India than Australia or Sarawak and (5) age at psychosis onset (AAO) was older in Sarawak than Australia or India. We suggest that site differences for living arrangements, drug use and DUP are culturally confounded. The schizoaffective site difference likely results from measurement bias. The AAO site difference, however, has no obvious cultural or measurement bias explanation. Therefore, this may be an ideal candidate for use in genetic studies, given that genetic variants affecting AAO have already been proposed.
Publisher: Public Library of Science (PLoS)
Date: 31-01-2011
Publisher: Springer Science and Business Media LLC
Date: 07-2014
Publisher: Cambridge University Press (CUP)
Date: 21-01-2005
DOI: 10.1017/S0033291704002880
Abstract: Background. We present results of a study of treated rates of schizophrenia among the Iban of Sarawak, Malaysia. Most Iban live in longhouses, each comprising a kindred group of up to 300 in iduals. Cultural practices such as minimal intermarriage with members of adjacent ethnic groups and in-depth genealogical knowledge make them a population suitable for genetic investigation. Iban culture is conducive to a focus on symptoms and illness, and to patterns of treatment-seeking behaviour that are enthusiastic and persistent. Method. We identified all known cases of psychotic disorder within a defined catchment area based on an exhaustive survey of available medical records. From corresponding Malaysian census data (91056 persons), we report rates of treated schizophrenia in the Iban population, using three diagnostic systems, as well as the demographic and clinical characteristics of these in iduals. Results. The most frequent presenting complaints were insomnia and aggression. We found higher treated rates for narrowly defined schizophrenia among males, but no significant gender difference for age of onset. Estimates of treated rates to age 55 years (per 10000) for narrow schizophrenia were 41·9 (ICD-10), 56·5 (DSM-IV), and 83 (RDC), while the rates for broad schizophrenia were 105·5, 103·2, and 107·5 respectively. Conclusions. Treated rates of schizophrenia were higher than the reported prevalence for many populations at risk, including many small-scale societies, although different methodological approaches may partly explain these findings. Given the cultural patterns of Iban treatment-seeking behaviour, treated rates of schizophrenia reported here may closely approximate the population prevalence of this disorder.
Publisher: Wiley
Date: 22-08-2013
DOI: 10.1111/APPY.12093
Publisher: Elsevier BV
Date: 12-2014
No related grants have been discovered for Peter Loa.