ORCID Profile
0000-0002-7140-2184
Current Organisation
Zhejiang University of Technology
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Elsevier BV
Date: 11-2016
Publisher: Elsevier BV
Date: 11-2017
Publisher: Elsevier BV
Date: 10-2017
Publisher: Informa UK Limited
Date: 10-03-2020
Publisher: Elsevier BV
Date: 02-2017
Publisher: Elsevier BV
Date: 2022
Publisher: Elsevier BV
Date: 08-2021
Publisher: Elsevier BV
Date: 07-2022
Publisher: Elsevier BV
Date: 02-2017
Publisher: World Scientific Pub Co Pte Lt
Date: 31-08-2015
DOI: 10.1142/S0219455415400118
Abstract: This paper investigates the free vibration and elastic buckling of sandwich beams with a stiff core and functionally graded carbon nanotube reinforced composite (FG-CNTRC) face sheets within the framework of Timoshenko beam theory. The material properties of FG-CNTRCs are assumed to vary in the thickness direction, and are estimated through a micromechanical model. The governing equations and boundary conditions are derived by using Hamilton's principle and discretized by employing the differential quadrature (DQ) method to obtain the natural frequency and critical buckling load of the sandwich beam. A detailed parametric study is conducted to study the effects of carbon nanotube volume fraction, core-to-face sheet thickness ratio, slenderness ratio, and end supports on the free vibration characteristics and buckling behavior of sandwich beams with FG-CNTRC face sheets. The vibration behavior of the sandwich beam under an initial axial force is also discussed. Numerical results for sandwich beams with uniformly distributed carbon nanotube-reinforced composite (UD-CNTRC) face sheets are also provided for comparison.
Publisher: Elsevier BV
Date: 04-2016
Publisher: Elsevier BV
Date: 07-2020
Publisher: IOP Publishing
Date: 09-08-2016
Publisher: Elsevier BV
Date: 06-2014
Publisher: IOP Publishing
Date: 09-12-2020
Abstract: Bionic soft grippers that can gently conform to the objects of any profiles and softly hold them with uniform pressure have been receiving considerable attention. To realize rapid and non-contact driving, a novel magneto-active soft gripper is developed in this paper. The gripper is embedded with magneto-active elastomer (MAE) actuators that are made from a mixture of a soft material substrate and hard magnetic fillers. Firstly, the MAE actuators doped with different contents of magnetic fillers are manufactured and magnetized by applying an external magnetic field. An experiment is designed to measure the magnetically induced deformation of MAE actuators under different external magnetic fields. On basis of the experimental study of MAE actuators, the magneto-active soft gripper is then designed and successfully fabricated. The gripping function and efficiency of the magneto-active soft gripper is demonstrated through an experimental study. Meanwhile, the maximum gripping force of grippers is measured and the effects of applied magnetic field and mass faction of magnetic fillers are examined. It is found that the gripping force increases as either magnetic field strength or magnetic fillers’ concentration increases but tends to be stable when the magnetic field is greater than 80 mT. When executing a gripping motion, the magneto-active soft gripper has a significantly short response time than the existing ones with other driving methods.
Publisher: Informa UK Limited
Date: 12-03-2018
Publisher: Mary Ann Liebert Inc
Date: 02-2022
Publisher: IOP Publishing
Date: 04-2021
Abstract: Adhesion of T cells to antigen presenting cells is mediated by the TCR–MHCp and LFA1–ICAM1 protein complexes. These intercellular protein complexes segregate and form characteristic special patterns in the cell contact zone. Previous studies have attempted to explain the mechanisms of formation of these patterns. While emphasis has been put on membrane elasticity and active cytoskeletal transport, it remains unclear whether and how the pattern formation process is related to lipid rafts, which are nanoscale molecular clusters enriched in cholesterol and saturated phospholipids in cell membranes. Using Monte Carlo simulations of a statistical mechanical model for T-cell adhesion, we find that lipid rafts can lead to the formation of intermediate pattern with a ring of LFA1–ICAM1 complexes around a central domain of TCR–MHCp complexes even in the absence of active transport of T-cell receptor (TCR) molecules toward the center of the contact zone. In the presence of active TCR transport, lipid rafts can accelerate the formation of this monocentric pattern. We also find that lipid rafts have a strong stabilizing effect on the monocentric pattern after removal of the active TCR transport. Our results not only help to explain recent experimental observations, but also demonstrate that lipid rafts can cooperate with active cytoskeletal transport during the immunological synapse formation.
Publisher: Elsevier BV
Date: 04-2023
Publisher: World Scientific Pub Co Pte Lt
Date: 02-07-2013
DOI: 10.1142/S0219455413500296
Abstract: The bistable characteristics of the irregular anti-symmetric cylindrical shell (IACS), such as [+α 1 / -α 2 / +α 2 / -α 1 ] lay-up, are presented using theoretical methodology and finite element (FE) analysis. A novel approach named two points loading method is used to induce a snap-through of the shell in FE analysis. Unlike regular [+α/ -α/ +α/ -α] lay-up anti-symmetric cylindrical shells, two or more different ply angles are included in the irregular anti-symmetric lay-up. Besides ply angles, the bistable characteristics of composite cylindrical shells with irregular anti-symmetric lay-ups are also affected by the sequence of lay-ups. Both analytical and FE results show that IACS with different bistable behaviors can be obtained by changing the ply angles or sequence of the lay-ups. It is very useful for the design and manufacture of the bistable structure. There is a reasonable agreement between analytical and FE predictions possible reasons of differences between analytical and FE results are given.
Publisher: Elsevier BV
Date: 12-2020
Publisher: MDPI AG
Date: 26-04-2020
Abstract: The bistability of anti-symmetric thin shallow cylindrical polymer composite shells, made of carbon fiber/epoxy resin, has already been investigated based on the uniform curvature and inextensible deformation assumptions by researchers in detail. In this paper, a non-uniform curvature model that considers the extensible deformations is proposed. Furthermore, a parametric modeling and automatic postprocessing plug-in component for the bistability analysis of polymer composite cylindrical shells is established by means of ABAQUS-software, by which the equilibrium configurations and the load-displacement curves during the snap process can be easily obtained. The presented analytical model is validated by the numerical simulation and literature models, while the factors affecting the bistability of anti-symmetric cylindrical shells are revisited. In addition, the planform effects of anti-symmetric cylindrical shells with rectangular, elliptical and trapezoidal planform are discussed. The results show that the presented analytical model improves the accuracy of the prediction of the principal curvature of second equilibrium configuration and agree well with the numerical results.
Publisher: Trans Tech Publications, Ltd.
Date: 08-2012
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMR.562-564.439
Abstract: Based on the discussion of the current research methods about the bi-stable composite shell, a novel experimental method named four points bending loading is presented to provide driving moments to snap an anti-symmetric bi-stable composite shell from one stable state to another. Then, the feasibility of this new method was confirmed using the finite element analysis software ABAQUS. Finally, the future work, which is to construct an experimental platform according the four points bending loading method, is pointed out.
Publisher: Frontiers Media SA
Date: 17-02-2023
DOI: 10.3389/FMOLB.2023.1154074
Abstract: Gaining insight into the two-dimensional receptor-ligand interactions, which play a significant role in various pivotal biological processes such as immune response and cancer metastasis, will deepen our understanding of numerous physiological and pathological mechanisms and contribute to biomedical applications and drug design. A central issue involved is how to measure the in situ receptor-ligand binding kinetics. Here, we review several representative mechanical-based and fluorescence-based methods, and briefly discuss the strengths and weaknesses for each method. In addition, we emphasize the great importance of the combination of experimental and computational methods in studying the receptor-ligand interactions, and further studies should focus on the synergistic development of experimental and computational methods.
Publisher: Elsevier BV
Date: 06-2015
Publisher: Elsevier BV
Date: 2018
Publisher: Elsevier BV
Date: 09-2019
Publisher: Elsevier BV
Date: 2017
Publisher: Elsevier BV
Date: 09-2020
Publisher: World Scientific Pub Co Pte Lt
Date: 22-10-2018
DOI: 10.1142/S0219455418501420
Abstract: This paper proposes a novel functionally graded (FG) concrete slab and investigates its thermal buckling and postbuckling performance using the finite-element (FE) method. The concrete slab consists of three homogeneous thick layers — a fiber-reinforced concrete layer, a geopolymer concrete layer, and a plain Portland cement (PPC) layer — with a thin FG layer between the thick layers. The mechanical properties of the thin FG layers are exponentially graded across the thickness direction. The effects of initial imperfection, the self-weight of the slab, and the friction between the slab and rigid foundation are considered in the analysis. The FE model is validated against the results reported in the literature. A comprehensive parametric study is conducted to examine the effects of the thickness and volume fraction index of the FG layer, initial imperfection, self-weight, friction, and slab slenderness ratio on the thermal buckling and postbuckling behaviors of the concrete slab. The numerical results demonstrate that the proposed FG slab exhibits remarkably better buckling and postbuckling resistance than a conventional PPC concrete slab and that the influences of both self-weight and friction are important and cannot be neglected.
Publisher: Frontiers Media SA
Date: 12-04-2021
DOI: 10.3389/FMOLB.2021.655662
Abstract: Cell-cell adhesion and the adhesion of cells to extracellular matrix are mediated by the specific binding of receptors on the cell membrane to their cognate ligands on the opposing surface. The adhesion receptors can exhibit affinity for nanoscale lipid clusters that form in the cell membrane. Experimental studies of such adhesion systems often involve a cell adhering either to a solid surface with immobile ligands or a supported lipid bilayer with mobile ligands. A central question in these cell-substrate adhesions is how the mobility of the ligands physically affects their binding to the adhesion receptors and thereby the behavior of the nanoscale lipid clusters associated with the receptors. Using a statistical mechanical model and Monte Carlo simulations for the adhesion of cells to substrates with ligands, we find that, for mobile ligands, binding to adhesion receptors can promote the formation of mesoscale lipid domains, which in turn enhances the receptor-ligand binding. However, in the case of immobile ligands, the receptor-ligand binding and the tendency for the nanoscale lipid clusters to further coalesce depend on the distribution of the ligands on the substrate. Our findings help to explain why different adhesion experiments for identifying the interplay between receptor-ligand binding and heterogeneities in cell membranes led to contradictory results.
Publisher: World Scientific Pub Co Pte Ltd
Date: 23-11-2020
DOI: 10.1142/S0219455420410151
Abstract: Functionally graded porous structures (FGPSs), characterized by a continuous spatial gradient in both porosity and material properties, have been considered as the new generation lightweight structures. Research activities on FGPSs have grown rapidly in recent years. This paper is devoted to review the existing research works on FGPSs and to highlight the important advances in this emerging area. It consists of: (i) a brief introduction of porous materials and Functionally graded porous materials (FGPMs) (ii) an elaboration of the key factor and micromechanical models related to material properties of FGPMs (iii) a comprehensive review of mechanical analysis of FGPSs (iv) a detailed discussion of the main challenges and future research directions (v) a conclusion.
Publisher: Elsevier BV
Date: 10-2022
Publisher: Elsevier BV
Date: 05-2020
Publisher: Elsevier BV
Date: 2018
Publisher: Elsevier BV
Date: 06-2016
Publisher: SAGE Publications
Date: 22-03-2018
Abstract: This paper investigates the effect of moisture on bistable characteristics of antisymmetric composite cylindrical by using experimental and finite element method. The bistable characteristics are characterized by the curvatures of antisymmetric composite cylindrical shells in different stable states and snap processes between the two stable states which are indicated by the load–displacement curve and snap load. The manufactured specimens after dried in the oven are immersed in distilled water to full saturation and the saturated salt solutions (MgCl 2 ) to full saturation. The specimen achieves different moisture that is immersed in distilled water at the different period until full saturation and in the saturated salt solution (MgCl 2 ) with the same period of saturation in distilled water. Specimens with different moisture are then mechanically loaded on a testing machine to transform between two stable states. Load–displacement curves are recorded in the computer, from which the snap loads can be found. After the test, the principal and twisting curvatures are captured by a digital image processing. The results are contrasted with hygroscopic influence on another kind of bistable composite structure (asymmetric cross-ply laminates) in this paper. The results show that the shapes and snap loads of antisymmetric composite cylindrical shells are influenced by the moisture increasing.
Publisher: Elsevier BV
Date: 10-2018
Publisher: Elsevier BV
Date: 12-2022
Publisher: Elsevier BV
Date: 04-2013
Publisher: Elsevier BV
Date: 02-2017
Publisher: Elsevier BV
Date: 12-2022
No related grants have been discovered for Helong Wu.