ORCID Profile
0000-0001-8526-8900
Current Organisation
University of Colorado Anschutz Medical Campus
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Publisher: European Association of Geochemistry
Date: 11-2017
Publisher: Informa UK Limited
Date: 19-04-2023
Publisher: Informa UK Limited
Date: 02-08-2022
Publisher: Elsevier BV
Date: 08-2018
Publisher: European Association of Geochemistry
Date: 10-2020
Publisher: Informa UK Limited
Date: 09-08-2022
DOI: 10.1080/14992027.2021.1957160
Abstract: To determine the attitudes of audiologists towards telehealth and use of telehealth for the delivery of ear and hearing services pre-, during- and post- the COVID-19 pandemic, and to identify the perceived effects of telehealth on services and barriers to telehealth. An online survey distributed through the International Society of Audiology and member societies. A total of 337 audiologists completing the survey between 23 June and 13 August 2020. There was a significant increase in the perceived importance of telehealth from before (44.3%) to during COVID-19 (87.1%), and the use of telehealth previous (41.3%), current (61.9%) and expected use of telehealth (80.4%). Telehealth was considered adequate for many audiology services, although hearing assessment and device fitting by telehealth received least support. Matters related to timeliness of services and reduction of travel were reported as the main advantages, but relationships between practitioners and clients may suffer with telehealth. Important barriers were technologies related to the client or remote site clinic-related items were moderate barriers, although more clinician training was a common theme provided through open-ended responses. The COVID-19 pandemic has resulted in audiologists having a more positive attitude towards and greater use of telehealth, but with some reservations.
Publisher: American Speech Language Hearing Association
Date: 02-06-2022
DOI: 10.1044/2021_AJA-21-00172
Abstract: Online reviews have become increasingly common for consumers to share their experiences about products and to assist potential consumers with decision making. The current study was aimed to understand the hearing aid user experience from online consumer reviews using qualitative analysis. The study used a qualitative thematic analysis to analyze open text responses from consumers leaving hearing aid reviews on the www.HearingTracker.com website. One thousand three hundred seventy-eight online consumer hearing aid reviews (open-text responses) were extracted and analyzed. Three domains emerged within the data set, containing 11 themes and 136 subthemes. Domain one (Clinical Processes) contained two themes: Hearing Assessment and Hearing Aid Acquisition. Domain two (The Device) contained five themes: Function, Performance, Physical, Device Management, and Maintenance. Domain three (The Person) contained four themes: Satisfaction, Quality of Life, Personal Adjustment, and Knowledge. The themes gave an understanding that there were a contribution of factors that formed part of a consumers hearing aid user experience. Hearing aid users described a range of positive, negative, and neutral descriptions online about their hearing aid user experience and gave advice to fellow hearing aid users helping clinicians improve their hearing aid fitting skills in practice. These findings have implications to future product development as well as service delivery model in terms of developing strategies for fostering patient-centered audiological practice.
Publisher: Elsevier BV
Date: 10-2012
Publisher: Society of Economic Geologists
Date: 23-11-2012
Publisher: Wiley
Date: 16-04-2015
Publisher: Wiley
Date: 03-01-2022
DOI: 10.1002/WRNA.1707
Abstract: The high‐throughput sequencing of cellular RNAs has underscored a broad effect of isoform ersification through alternative splicing on the transcriptome. Moreover, the differential production of transcript isoforms from gene loci has been recognized as a critical mechanism in cell differentiation, organismal development, and disease. Yet, the extent of the impact of alternative splicing on protein production and cellular function remains a matter of debate. Multiple experimental and computational approaches have been developed in recent years to address this question. These studies have unveiled how molecular changes at different steps in the RNA processing pathway can lead to differences in protein production and have functional effects. New and emerging experimental technologies open exciting new opportunities to develop new methods to fully establish the connection between messenger RNA expression and protein production and to further investigate how RNA variation impacts the proteome and cell function. This article is categorized under: RNA Processing Splicing Regulation/Alternative Splicing Translation Regulation RNA Evolution and Genomics Computational Analyses of RNA
Publisher: Springer Science and Business Media LLC
Date: 02-08-2013
Publisher: Informa UK Limited
Date: 17-06-2022
DOI: 10.1080/14992027.2021.1937348
Abstract: This study surveyed the effects of the COVID-19 pandemic on the audiology workplace. The study used a cross-sectional survey design for audiologists across the globe ( Participants represented varied work settings and audiology services. Only a third (31.5%) provided psychosocial support, which may be important during the pandemic, as part of their services. Almost all (97%) audiologists reported changes to their workplace, with 76.4% reporting reduced caseloads during the COVID-19 pandemic. When rating their current and anticipated work conditions, 38.7% reported reduced working hours although only 13.8% anticipated reduced working hours in 6-months' time. Audiologists ranked services such as access to hearing assessment, hearing device adjustment and maintenance, and general audiological support as being more important during the pandemic than services such as psychosocial, emotional and tinnitus support. The COVID-19 pandemic has resulted in significant disruptions to audiological practice that highlights the need to adapt and incorporate new audiological practices including telehealth, to ensure patients have continued access to care and clinics remain sustainable during the ongoing COVID-19 pandemic and recovery phase.
Publisher: Informa UK Limited
Date: 13-06-2021
DOI: 10.1080/14992027.2021.1931487
Abstract: To explore the publicised opinions of consumers actively participating in online hearing aid reviews. A retrospective design examining data generated from an online consumer review website (www.HearingTracker.com). Qualitative data (open text responses) were analysed using the open source automated topic modelling software IRaMuTeQ (www.iramuteq.org/) to identify themes. Outputs were compared with quantitative data from the consumer reviews (short response questions exploring hearing aid performance and benefit, and some meta-data such as hearing aid brand and years of hearing aid ownership). 1378 online consumer hearing aid reviews. Six clusters within two domains were identified. The domain Device Acquisition included three clusters: Although online hearing aid consumers indicate positive performance on multiple-choice questions relating to hearing aid performance and benefit, their online reviews describe a number of barriers limiting their success. Hearing healthcare clinicians must employ a personalised approach to audiological rehabilitation to ensure in idual clients' needs are met.
Publisher: American Speech Language Hearing Association
Date: 10-09-2021
DOI: 10.1044/2021_AJA-20-00223
Abstract: The study examined psychologically meaningful language dimensions (i.e., social and emotional dimensions, health dimensions, and personal concerns) within online consumer reviews on hearing health care services using an automated textual analysis approach. Nine thousand six hundred twenty-two consumer reviews of hearing health care services, including an open-ended question (i.e., free text response to the prompt “share details of your own experience at this place”) and an overall rating (on a 5-point scale ranging from “very good” to “very poor”) were extracted from Google.com from 40 different cities across the United States. In addition, some metadata about the cities (i.e., region, population size, median age, percentage of older adults) were also recorded. Text responses were analyzed using the automated Linguistic Inquiry and Word Count software for selected language dimensions. The language dimensions of online hearing health care reviews were descriptively compared with language dimensions observed in the natural language of typical bloggers. Language dimensions from free text responses were correlated with quantitative overall experience ratings. Automated linguistic analysis showed that consumer reviews on hearing health care services had higher social processes, positive emotions, hearing, health, money, and work, and lower negative emotions and time-awareness when compared to typical bloggers. Examining the association between overall experience rating and the language dimensions revealed two broad findings. First, higher engagement of consumers in terms of social processes, positive emotions, hearing, and work dimensions was related to higher experience ratings. Second, higher engagement of consumers in terms of negative emotions, time awareness, and money was related to lower experience ratings. Online reviews contain information about various dimensions (i.e., social and emotional dimensions as well as personal concerns) that have bearing toward the way in that they rate their health care experiences. Automated linguistic analysis of consumer reviews appears helpful in identifying gaps in service delivery that may influence consumer experience.
Publisher: American Association for the Advancement of Science (AAAS)
Date: 08-01-2021
Abstract: Carbonaceous chondritic meteorites are thought to be fragments broken off parent bodies that orbit in the outer Solar System, largely unaltered since their formation. These meteorites contain evidence of reactions with liquid water that was thought to have been lost or completely frozen billions of years ago. Turner et al. examined uranium and thorium isotopes in several carbonaceous chondrites, finding nonequilibrium distributions that imply that uranium ions were transported by fluid flow. Because this signature disappears after several half-lives of the radioactive isotopes, the meteorites must have been exposed to liquid within the past million years. The authors suggest that ice may have melted during the impacts that ejected the meteorites from their parent bodies. Science , this issue p. 164
Publisher: Springer Science and Business Media LLC
Date: 15-08-2019
DOI: 10.1038/S41598-019-47790-5
Abstract: Alzheimer’s disease is associated with the production of Cu rich aβ fibrils. Because monitoring the changes in Cu level of organs has been proposed to follow the evolution of the disease, we analyzed the copper isotopic composition of serum and brain of APPswe/PSEN1dE9 transgenic mice, a model of Alzheimer’s disease, and wild-type (WT) controls. Serum composition of 3, 6, 9 and 12-month-old mice, as well as the composition of 9 brains of 12-month-old mice are reported. In WT mice, brains were ~1‰ isotopically heavier than serum, and the Cu isotopic composition of the serum was isotopically different between males and females. We propose that this effect of sex on the Cu isotopic budget of the serum may be related to a difference of Cu speciation and relative abundance of Cu carriers. Brains of APPswe/PSEN1dE9 mice were slightly lighter than brains of WT mice, while not statistically significant. This trend may reflect an increase of Cu(I) associated with the formation of Aβ fibrils. The Cu isotopic composition of the brains and serum were correlated, implying copper transport between these two reservoirs, in particular a transfer of Cu(I) from the brain to the serum. Altogether, these data suggest that Cu stable isotopic composition of body fluid may have the potential to be used as detection tools for the formation of Aβ fibrils in the brain, but further work has to be done.
Publisher: Elsevier BV
Date: 05-2017
Publisher: Elsevier BV
Date: 12-2019
Publisher: Elsevier BV
Date: 10-2021
Publisher: American Geophysical Union (AGU)
Date: 10-2021
DOI: 10.1029/2021JB022026
Abstract: Earth's accretion history for volatile elements, and the origin of their depletions with respect to the Sun and primitive meteorites, continue to be debated. Two end‐member scenarios propose either that volatile elements were delivered during the main phases of accretion and differentiation, or that the Earth accreted from materials largely devoid of volatiles with late addition of volatile‐rich materials. Experiments evaluating the effect of metal–silicate equilibrium on elemental and isotopic distribution of volatile and siderophile elements such as Sn can help to distinguish between these scenarios. In this study, we have systematically investigated the relative influence of temperature, pressure, oxygen fugacity, and metal and silicate composition on the metal–silicate partioning behavior of Sn, from 2 to 20 GPa and 1,700 to 2,573 K, indicating that Sn siderophility noticeably decreases with temperature and S content of the metal but increases dramatically with pressure. A resolvable isotopic fractionation factor between metal and silicate suggests that core–mantle equilibrium temperatures (∼3,000 K) could potentially generate a Sn isotopic composition of the mantle lighter than the core by 150–200 ppm/amu. Core formation modeling shows that the volatiles were added during the last 10% of the accretion history. A final core containing 2.5 to 3.5 wt.% S is required. Furthermore, modeling of the BSE isotopic composition argues for a late Sn delivery on Earth with carbonaceous chondrite‐like material as the most likely source of volatiles. Therefore, both elemental and isotopic approaches converge toward an identical volatile accretion scenario, involving a late volatile delivery.
Publisher: Elsevier BV
Date: 2014
Publisher: American Speech Language Hearing Association
Date: 10-09-2021
DOI: 10.1044/2021_AJA-21-00041
Abstract: The aim of this study was to examine experiences of hearing health care services as described in online consumer reviews. This study used a cross-sectional design. Online consumer reviews about hearing health care services generated from Google.com to an open-ended question “Share details of your own experience at this place” and perceived overall experience (indicated on a 5-point rating scale: “very good” to “very poor”) were extracted from 40 different cities across the United States. The open text contributed a text corpus of 9,622 unique consumer reviews. These responses were analyzed with the cluster analysis approach using an open-source automated text analysis software program, IRaMuTeQ, to identify key themes. Association between clusters and consumer experience ratings as well as consumer metadata (percentage of older adults in the city, region) were examined using the chi-square analysis. The majority of consumers appeared satisfied with their hearing health care services, with nearly 95% of consumers reporting “very good” and “good” on the global experience scale. The analysis of text responses resulted in seven clusters within two domains. Domain 1 (Clinical Processes) included the three clusters: administration processes, perceived benefits, and device acquisition. Domain 2 (Staff and Service Interactions) included the four clusters: clinician communications, staff professionalism , customer service, and provider satisfaction . Content relating to administration processes was associated with overall rating regarding the hearing health care service experience. Consumer's reviews relating to administration processes mostly described negative experiences, and these participants were more inclined to provide poorer overall experience ratings. In addition, city characteristics (i.e., percentage of older adults, region) had bearing toward what elements of hearing health care services are highlighted more in the consumer reviews. Consumers comment on a variety of elements when describing their experiences with hearing health care services. Experiences reported in most clusters were generally positive, although some concerns in the “clinical process” are associated with lower satisfaction. Employing patient-centered strategies and ensuring patients have good experiences in the areas of concern may help improve both patient experience and their satisfaction. 0.23641/asha.16455924
Publisher: Elsevier BV
Date: 11-2017
Publisher: American Speech Language Hearing Association
Date: 10-09-2021
DOI: 10.1044/2021_AJA-21-00061
Abstract: Online reviews have been used by hearing aid owners to share their experiences and to provide suggestions to potential hearing aid buyers, although they have not been systematically examined. The study was aimed at examining the hearing aid consumer reviews using automated linguistic analysis, and how the linguistic variables relate to self-reported hearing aid benefit and satisfaction ratings. The study used a cross-sectional design. One thousand three hundred seventy-eight consumer hearing aid reviews (i.e., text response to open-ended question), self-reported benefit and satisfaction ratings on hearing aids in a 5-point scale with meta-data (e.g., hearing aid brand, technology level) extracted from the Hearing Tracker website were analyzed using automated text analysis method known as the Linguistic Inquiry and Word Count. Self-reported hearing aid benefit and satisfaction ratings were high (i.e., mean rating of 4.04 in a 5-point scale). Examining the association between overall rating and the key linguistic variables point to two broad findings. First, the more people were personally, socially, and emotionally engaged with the hearing device experience, the higher they rated their hearing device(s). Second, a minimal occurrence of clinic-visit language dimensions points to factors that likely affect benefit and satisfaction ratings. For ex le, if people mention paying too much money (money), their overall ratings are generally lower. Conversely, if people write about their health or home, the ratings were higher. There was no significant difference in linguistic analysis across different hearing aid brands and technology levels. Hearing aid consumers are generally satisfied with their hearing device(s), and their online reviews contain information about social/emotional dimensions as well as clinic-visit related aspects that have bearing toward hearing aid benefit and satisfaction ratings. These results suggest that the natural language used by consumers provide insights on their perceived benefit/satisfaction from their hearing device.
Publisher: Elsevier BV
Date: 04-2019
Publisher: Elsevier BV
Date: 11-2010
Publisher: Geological Society of America
Date: 02-2009
DOI: 10.1130/G25200A.1
Publisher: Royal Society of Chemistry (RSC)
Date: 2013
DOI: 10.1039/C3JA50022E
Publisher: American Astronomical Society
Date: 21-09-2011
Publisher: Elsevier BV
Date: 11-2020
Publisher: Wiley
Date: 24-01-2020
DOI: 10.1111/GGR.12310
Abstract: Recent developments in lifier hardware enable low‐noise measurements of exceedingly small ion beams in isotope ratio analysis, yielding higher precision from smaller s les than ever before. To date, these lifiers have largely been employed in thermal ionisation instruments, with few applications using plasma‐source (i.e., MC‐ICP‐MS) instruments. Here, we demonstrate the utility of these new generation 10 13 Ω lifiers in MC‐ICP‐MS, employing Pt isotopes as a case study, a system that could greatly benefit from the promised advances. The data demonstrate that for s les with low Pt abundance, for a modest increase in uncertainties, the amount of s le required can be reduced by a factor of 50–100. This technique thereby opens up new possibilities for analysis of s les that have low Pt mass fractions or were otherwise impossible to obtain in sufficient quantities.
Publisher: Elsevier BV
Date: 04-2019
Location: Sweden
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: Denmark
Location: United States of America
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for John B. Creech.